Brain Metastases from Primary Tumors Volume 1

Brain Metastases from Primary Tumors Volume 1 PDF Author: M. A. Hayat
Publisher: Academic Press
ISBN: 0128010959
Category : Medical
Languages : en
Pages : 275

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Book Description
With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. Brain Metastases from Primary Tumors Volume 1 fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types – lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age and gender related trends are also discussed, as is the use of biomarkers for early detection. - The only comprehensive reference detailing the link between primary cancers and brain metastases - Aids the target audience in determining the incidence of brain metastases in patients with a primary cancer - Provided education about the potential use of biomarkers for early detection, diagnosis and prevention of the spread of primary cancer to the brain - Documents temporal and gender-related trends in brain metastases from other cancers - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Brain Metastases from Primary Tumors Volume 1

Brain Metastases from Primary Tumors Volume 1 PDF Author: M. A. Hayat
Publisher: Academic Press
ISBN: 0128010959
Category : Medical
Languages : en
Pages : 275

Get Book Here

Book Description
With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. Brain Metastases from Primary Tumors Volume 1 fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types – lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age and gender related trends are also discussed, as is the use of biomarkers for early detection. - The only comprehensive reference detailing the link between primary cancers and brain metastases - Aids the target audience in determining the incidence of brain metastases in patients with a primary cancer - Provided education about the potential use of biomarkers for early detection, diagnosis and prevention of the spread of primary cancer to the brain - Documents temporal and gender-related trends in brain metastases from other cancers - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Brain Metastases from Primary Tumors, Volume 3

Brain Metastases from Primary Tumors, Volume 3 PDF Author: M. A. Hayat
Publisher: Academic Press
ISBN: 0128035595
Category : Medical
Languages : en
Pages : 385

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Book Description
Brain Metastases from Primary Tumors Volume Three: Epidemiology, Biology, and Therapy of Melanoma and Other Cancers provides a comprehensive overview of the metastasis of cancer, the main cause of approximately 90% of cancer associated deaths, yet the mechanisms governing this clinically important process remain poorly understood. Melanoma is the third most common diagnosis among patients with brain metastases, after lung and breast cancer. Approximately 75% of patients with metastatic melanoma develop brain metastases during the course of their disease. Although tumorigenesis of melanoma remains poorly understood, recent advances in gene expression profiling have revealed molecular mechanisms of this deadly disease. In addition, high-throughput gene expression has many advantages over techniques in cancer transcriptomic studies and has led to the discovery of numerous diagnostic, prognostic, and therapeutic targets, which are also detailed in this book. The book discusses the link between primary tumors and brain metastasis of melanoma, including molecular mechanisms, treatment options, prognosis, and general applications. Comprehensive chapters discuss systemic therapy, integrin inhibitors, stereotaxic radiosurgery, and more, making this book a great resource for neurooncologists, neurosurgeons, neurologists, and cancer researchers. - Presents the only comprehensive reference detailing the link between primary cancers and brain metastases in melanoma - Aids the target audience in discussing various treatment options for patients with brain metastases from melanoma - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Brain Metastases

Brain Metastases PDF Author: Jeffrey Raizer
Publisher: Springer Science & Business Media
ISBN: 0387692215
Category : Medical
Languages : en
Pages : 240

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Book Description
Brain metastases are the most dreaded complication of systemic cancer, affecting some 170,000 people a year, a far greater incidence than primary brain tumors. This book presents current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neurosurgeons, radiation oncologists, medical oncologists, and neuron-oncologists, and as an overview for physicians in training.

Central Nervous System Metastases

Central Nervous System Metastases PDF Author: Manmeet Ahluwalia
Publisher: Springer Nature
ISBN: 3030234177
Category : Medical
Languages : en
Pages : 411

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Book Description
This book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives. Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach. Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.

Central Nervous System Metastases

Central Nervous System Metastases PDF Author: Rohan Ramakrishna
Publisher: Springer Nature
ISBN: 303042958X
Category : Medical
Languages : en
Pages : 725

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Book Description
This is a multi-specialty book on the diagnosis, evaluation, and treatment of CNS metastases of the brain and spine. Written by renowned experts in their fields, the book covers essential contemporary topics in CNS metastases care. The book is divided into seven parts that begin with chapters that cover the fundamental biology of disease so that subsequent chapters on imaging, diagnosis, treatment, and palliation can be properly contextualized. This text also provides a framework for understanding the biology of radiation therapy so that radiation treatment options of the brain and spine can be more fully understood. New medications and technologies are reviewed from the perspective of maximizing efficacy and minimizing toxicity, independently and as combinatorial therapy. Central Nervous System Metastases: Diagnosis and Treatment serves as a practical reference for health care providers and trainees. It provides the comprehensive, detailed perspective required to provide holistic care to patients with metastatic disease to the brain and spine.

Epilepsy and Brain Tumors

Epilepsy and Brain Tumors PDF Author: Herbert B. Newton
Publisher: Elsevier
ISBN: 0124171265
Category : Medical
Languages : en
Pages : 292

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Book Description
Patients with brain tumor-related epilepsy (BTRE) suffer from two serious pathologies simultaneously – a brain tumor and a secondary form of epilepsy. Although there has been remarkable progress in BTRE research in recent years, it remains an on-going challenge for clinicians and continues to stimulate much debate in the scientific community. This volume is the first to be completely dedicated to BTRE, and in doing so it explores issues faced by the health care team as well as some of the novel and promising directions that future research may take. Epilepsy and Brain Tumors is not only a complete reference on BTRE but also a practical guide based on clinical experiences, with a comprehensive collection of presentations from international experts who share some of the latest discoveries and their approaches to tackling a wide range of difficult and complex issues. - Includes coverage of epidemiology, pathology and treatment of both primary and metastatic brain tumors - Offers additional insight into supportive care, incidence in children, focal epileptogenesis, clinical evaluation, antiepileptic drugs, surgical treatment, cognitive rehabilitation, and more - Chapters authored and edited by leaders in the field around the globe – the broadest, most expert coverage available

Metastatic Disease of the Nervous System

Metastatic Disease of the Nervous System PDF Author: David Schiff
Publisher: Elsevier
ISBN: 0444638792
Category : Medical
Languages : en
Pages : 304

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Book Description
Metastatic Disease of the Nervous System, Volume 149, begins with an overview of the impact and range of direct neoplastic involvement of the central and peripheral nervous system, comprehensively reviewing all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy in their management, and the complications of these interventions. The clinical manifestations, diagnosis and treatment of leptomeningeal, dural, spinal epidural and plexus metastases are also covered in detail. - Covers all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy - Presents a multidisciplinary review of the evidence regarding accuracy of diagnostic testing and evidence-based reviews of therapies - Addresses metastatic diseases of the nervous system for residents, fellows and clinicians in neurology and oncology

Neurologic Complications of Cancer

Neurologic Complications of Cancer PDF Author: Lisa M. DeAngelis
Publisher: OUP USA
ISBN: 0195366743
Category : Medical
Languages : en
Pages : 652

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Book Description
Patients with cancer can suffer from a bewildering variety of neurologic signs and symptoms. The neurologic symptoms are often more disabling than the primary cancer. Symptoms including confusion, seizures, pain and paralysis may be a result of either metastases to the nervous system or one of several nonmetastatic complications of cancer. The physician who promptly recognizes neurologic symptoms occurring in a patient with cancer and makes an early diagnosis may prevent the symptoms from becoming permanently disabling or sometimes lethal. This monograph, an update of the first edition published in 1995, is divided into 3 sections. The first classifies the wide variety of disorders that can cause neurologic symptoms the patient with cancer, discusses the pathophysiology of nervous system metastases, the pathophysiology and treatment of brain edema and the approach to supportive care of common neurologic symptoms such as seizures, pain, and side effects of commonly used supportive care agents. The second section is devoted to nervous system metastases, addressing in turn, brain, spinal cord, meningeal and cranial and peripheral nerve metastases, describing clinical symptoms, approach to diagnosis and current treatment. The third section addresses several nonmetastatic complications of cancer and includes sections on vascular disease, infections, metabolic and nutritional disorders, side chemotherapy, radiation and other diagnostic and therapeutic procedures. The final chapter addresses paraneoplastic syndromes.The book is intended for practicing oncologists, neurologists, neurosurgeons and radiation oncologists as well as internists who treated patients with cancer. Our attempt was to write a book that would assist oncologists in understanding neurologic problems and neurologists in understanding oncologic problems. The book is also intended for physicians training to specialize in any of the above areas. It includes a practical approach to the diagnosis and management of patients with neurologic disease who are with known to have cancer or in whom cancer is suspected.

Evidence based practice in Neuro-oncology

Evidence based practice in Neuro-oncology PDF Author: Supriya Mallick
Publisher: Springer
ISBN: 9789811626616
Category : Medical
Languages : en
Pages : 0

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Book Description
This book provides evidence-based management in neuro-oncology covering all aspects such as pathology, radiology, surgery, radiation, and chemotherapy.The field of neuro-oncology is rapidly evolving and new evidence is coming out every day towards the optimal management of brain tumors. This necessitates a requirement of a complete guide that shall provide an evidence-based and personalized approach towards dealing with patients. This book also covers recent advances in personalized treatment formed through the relevant basis of anatomy, imaging, radiology, surgical, radiation and systemic treatment of brain and spinal tumors. In addition it also covers the , practical aspects of the planning of the Gamma knife and other radio surgical aspects. The book shall provide valuable assistance to practicing neuro-oncologists to practice better evidence-based personalized medicine.

Neuro-Oncology

Neuro-Oncology PDF Author: Jeremy Rees
Publisher: Elsevier Health Sciences
ISBN: 145570377X
Category : Medical
Languages : en
Pages : 481

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Book Description
Neuro-Oncology—a new title in the Blue Books of Practical Neurology series—is a concise and clinically applicable guide to this dynamic subspecialty. Jeremy Rees, PhD, MRCP and Patrick Y. Wen, MD present the most current information on the treatment and management of primary CNS tumors, secondary brain tumors, and the neurological complications of other cancers and their therapies in a format and scope appealing to both the general neurologist and the subspecialist. Access comprehensive coverage of treatment for adult and pediatric conditions—including tumors of the spinal cord as well as the brain. Find coverage of recent advances easily thanks to the emphasis on the latest clinical and laboratory findings and their implications for clinical management and treatment. Apply the possibilities and outcomes of neuro-oncologic surgery within the context of neurologic practice. Address the neurologic complications of cancer and its treatment as well as of primary and secondary tumors. Tap into the global perspectives of experts from all around the world for a multi-disciplinary approach to practice.