Bone Regulatory Factors

Bone Regulatory Factors PDF Author: Antonio Pecile
Publisher: Springer Science & Business Media
ISBN: 1475715080
Category : Medical
Languages : en
Pages : 295

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Book Description
Includes all lectures presented at the NATO ASI Course on title] held in Erice, Sicily, May 1989. Covers morphological, chemical, biochemical, physiological and pathophysiological aspects of bone formation and resorption, focusing on regulatory factors and indicating the new directions that are ope

Principles of Bone Regeneration

Principles of Bone Regeneration PDF Author: Jona J. Sela
Publisher: Springer Science & Business Media
ISBN: 146142058X
Category : Technology & Engineering
Languages : en
Pages : 161

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Book Description
Principles of Bone Regeneration is a timely publication that addresses the modern aspects of bone healing and repair. This exciting new volume details the convergence of the different experimental and clinical approaches designed for the study and treatment of bone healing in its diverse forms and under varying conditions. Bone healing is affected by a multitude of genetic, environmental, mechanical, cellular and endocrine variables which eventually lead to changes in gene expression that enhance the guided action of osteoblasts (and chondroblasts) to lay down bone that restores, or even improves, the skeletal load bearing capacity. Recent breakthroughs in understanding the regulatory aspects of bone formation and resorption, in both research and clinical arenas offer new modalities to induce, enhances and guide repair processes in bone for the benefit of millions of patients with conditions such as nonunion fractures, critical size defects, orthodontic tooth movement, periodontal bone loss, intraosseous implants and deformed bones.

Bone Regulatory Factors

Bone Regulatory Factors PDF Author: Antonio Pecile
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 312

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Book Description
Includes all lectures presented at the NATO ASI Course on [title] held in Erice, Sicily, May 1989. Covers morphological, chemical, biochemical, physiological and pathophysiological aspects of bone formation and resorption, focusing on regulatory factors and indicating the new directions that are ope

Bone Health and Osteoporosis

Bone Health and Osteoporosis PDF Author: United States Public Health Service
Publisher:
ISBN: 9781410219275
Category : Health & Fitness
Languages : en
Pages : 0

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Book Description
This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.

Bone Formation

Bone Formation PDF Author: Felix Bronner
Publisher: Springer Science & Business Media
ISBN: 9781852337179
Category : Medical
Languages : en
Pages : 184

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Book Description
Bone research in recent years has generated much new knowledge, in large measure because of the broad public health implications of osteoporosis and related bone disorders. Bone Formation, the first in a series entitled Topics in Bone Biology, evaluates this new information and formulates novel insights and hypotheses within the broad framework of current knowledge. An easy-to handle and to read work, with concise reviews that are extensively referenced, the chapters in this book are written by internationally known authorities. Particular emphasis is on osteoporosis and related disorders of diminished bone formation. Among the general topics treated is a chapter on biomechanical aspects of bone formation, not often considered in relation to diseases of bone formation. The book constitutes essential reading for those entering the field of bone biology and those who wish to become familiar with up-to-date information in a particular area of bone research.

Bone Regulators and Osteoporosis Therapy

Bone Regulators and Osteoporosis Therapy PDF Author: Paula H. Stern
Publisher: Springer Nature
ISBN: 3030573788
Category : Medical
Languages : en
Pages : 518

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Book Description
This volume is designed to provide an understanding of current and potential therapies for osteoporosis. The opening chapter introduces the cells of bone and their interactions. Several following chapters describe factors affecting bone including systemic hormones with significant effects on bone, and local mediators including growth factors, prostaglandins, cytokines and chemokines. Topics that have commanded particular attention recently are calcium, FGF-23, nervous system bone interactions. Drugs that cause bone loss provide important information on mechanism as well as therapeutic considerations. An overview of the genetics of bone disorders and a discussion of the pathophysiology of osteoporosis establish the clinical context. The final chapters discuss current and potential osteoporosis treatments.

Bone Regulatory Factors

Bone Regulatory Factors PDF Author: Antonio Pecile
Publisher:
ISBN: 9781475715095
Category :
Languages : en
Pages : 304

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Book Description


The Regulation of Bone Remodeling by TGF-[beta]

The Regulation of Bone Remodeling by TGF-[beta] PDF Author: Adrian Erlebacher
Publisher:
ISBN:
Category : Bone remodeling
Languages : en
Pages : 538

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Book Description


Bone Resorption

Bone Resorption PDF Author: Felix Bronner
Publisher: Springer Science & Business Media
ISBN: 9781852338121
Category : Medical
Languages : en
Pages : 216

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Book Description
This book reflects the meteoric increase in knowledge regarding bone remodeling including molecular understanding of osteoclast development, regulatory molecules such as cytokines, pathophysiology and pharmaceutical development to treat osteoclast function. Rapid publication of an up-to-date volume addressing these issues by experts in the field, an asset to any library of clinical endocrinologists and rheumatologists, is a valuable read for those entering the scientific arena of bone remodeling research. It integrates recent technological advances with foundation data to provide a comprehensive view of bone resorption, and also links information gained from the genetic and molecular to the physiological and clinical levels. It is addressed to clinical practitioners, nutrition scientists, researchers and students, who seek a fundamental understanding of this important subject. An invaluable publication for the community of medical specialists- internists, endocrinologists, nephrologists, orthopaedists- as well as dental, paramedical and nursing practitioners.

Engineered Bone

Engineered Bone PDF Author: Herve Petite
Publisher: CRC Press
ISBN: 149871353X
Category : Science
Languages : en
Pages : 225

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Book Description
This book addresses relevant issues that tissue-engineering researchers must consider when planning new strategies, especially in the bone and cartilage field. It describes transcription factors that are essential in bone development, and deals with bone healing.

Multiscale Mechanobiology of Bone Remodeling and Adaptation

Multiscale Mechanobiology of Bone Remodeling and Adaptation PDF Author: Peter Pivonka
Publisher: Springer
ISBN: 3319588451
Category : Science
Languages : en
Pages : 295

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Book Description
The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.