Author: Sushil K. Sarna
Publisher: Biota Publishing
ISBN: 1615041516
Category : Medical
Languages : en
Pages : 159
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Book Description
Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.
Author: Joseph Anderson, MD
Publisher: Springer Science & Business Media
ISBN: 1607613980
Category : Medical
Languages : en
Pages : 210
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Book Description
Colorectal Cancer Screening provides a complete overview of colorectal cancer screening, from epidemiology and molecular abnormalities, to the latest screening techniques such as stool DNA and FIT, Computerized Tomography (CT) Colonography, High Definition Colonoscopes and Narrow Band Imaging. As the text is devoted entirely to CRC screening, it features many facts, principles, guidelines and figures related to screening in an easy access format. This volume provides a complete guide to colorectal cancer screening which will be informative to the subspecialist as well as the primary care practitioner. It represents the only text that provides this up to date information about a subject that is continually changing. For the primary practitioner, information on the guidelines for screening as well as increasing patient participation is presentedd. For the subspecialist, information regarding the latest imaging techniques as well as flat adenomas and chromoendoscopy are covered. The section on the molecular changes in CRC will appeal to both groups. The text includes up to date information about colorectal screening that encompasses the entire spectrum of the topic and features photographs of polyps as well as diagrams of the morphology of polyps as well as photographs of CT colonography images. Algorithms are presented for all the suggested guidelines. Chapters are devoted to patient participation in screening and risk factors as well as new imaging technology. This useful volume explains the rationale behind screening for CRC. In addition, it covers the different screening options as well as the performance characteristics, when available in the literature, for each test. This volume will be used by the sub specialists who perform screening tests as well as primary care practitioners who refer patients to be screened for colorectal cancer.
Author: J. Gordon Betts
Publisher:
ISBN: 9781947172807
Category :
Languages : en
Pages : 0
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Book Description
Author: Andrew Motion
Publisher:
ISBN: 9780571228041
Category : Poets, English
Languages : en
Pages : 326
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Book Description
A portrait of the bond between a mother and her son, and the capturing of a moment in time before the loss of childhood innocence.
Author: Jerome J. DeCosse
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 280
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Book Description
Author: William Harvey
Publisher: Courier Corporation
ISBN: 0486688275
Category : Science
Languages : en
Pages : 241
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Book Description
Classic of science reports how Harvey's theory of the circulation of the blood came into being. Reproduces the English translation made during Harvey's lifetime.
Author: American Bar Association. House of Delegates
Publisher: American Bar Association
ISBN: 9781590318737
Category : Law
Languages : en
Pages : 216
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Book Description
The Model Rules of Professional Conduct provides an up-to-date resource for information on legal ethics. Federal, state and local courts in all jurisdictions look to the Rules for guidance in solving lawyer malpractice cases, disciplinary actions, disqualification issues, sanctions questions and much more. In this volume, black-letter Rules of Professional Conduct are followed by numbered Comments that explain each Rule's purpose and provide suggestions for its practical application. The Rules will help you identify proper conduct in a variety of given situations, review those instances where discretionary action is possible, and define the nature of the relationship between you and your clients, colleagues and the courts.
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241548371
Category : Business & Economics
Languages : en
Pages : 442
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Book Description
The Pocket Book is for use by doctors nurses and other health workers who are responsible for the care of young children at the first level referral hospitals. This second edition is based on evidence from several WHO updated and published clinical guidelines. It is for use in both inpatient and outpatient care in small hospitals with basic laboratory facilities and essential medicines. In some settings these guidelines can be used in any facilities where sick children are admitted for inpatient care. The Pocket Book is one of a series of documents and tools that support the Integrated Managem.
Author: Mark B. Salter
Publisher: U of Minnesota Press
ISBN: 1452944512
Category : Political Science
Languages : en
Pages : 537
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Book Description
Building on recent debates in critical social theory and international relations, Making Things International I: Circuits and Motion presents twenty-five essays that engage the global, the local, and the international through the lens of objects. It represents the first substantial new materialist intervention in global politics and international relations, offering a diverse and provocative set of reflections on how different objects create, sustain, complicate, and trouble the international. Problematizing the stuff of global life, Making Things International focuses on contemporary materialist scholarship on the international realm. The first of two volumes, these original contributions by both new and established scholars examine how war, diplomacy, trade, communication, and mobile populations are made by things: weapons, vehicles, shipping containers, commodities, passports, and more. The authors demonstrate how mundane, everyday objects—not normally understood as international—are in fact deeply implicated in how we think of the world: blood, garbage, viruses, traffic lights, clocks, memes, and ships’ ballast. Contributors: Michele Acuto, U College London; Peter Adey, Royal Holloway U of London; Rune Saugmann Andersen, U of Helsinki; Jessica Auchter, U of Tennessee at Chattanooga; Mike Bourne, Queen’s U Belfast; Kathleen P. J. Brennan; Elizabeth Cobbett, U of East Anglia; Stefanie Fishel, Hobart and William Smith Colleges; Emily Gilbert, U of Toronto; Jairus Grove, U of Hawai‘i at Manoa; Charlie Hailey, U of Florida; John Law, Open U; Wen-yuan Lin, National Tsing-hua U; Oded Löwenheim, Hebrew U of Jerusalem; Chris Methmann; Benjamin J. Muller, U of Western Ontario; Can E. Mutlu, Bilkent U; Geneviève Piché; Joseph Pugliese, Macquarie U; Katherine Reese; Michael J. Shapiro, U of Hawai‘i at Manoa; Benjamin Stephan; Daniel Vanderlip; William Walters, Carleton U; Melissa Autumn White, U of British Columbia; Lauren Wilcox, U of Cambridge; Yvgeny Yanovsky.
Author: Centers for Disease Control and Prevention CDC
Publisher: Oxford University Press
ISBN: 0190628634
Category : Medical
Languages : en
Pages : 705
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Book Description
THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.
