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Author: Walter H. Seegers
Publisher: Academic Press
ISBN: 1483225453
Category : Medical
Languages : en
Pages : 641
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Book Description
Blood Clotting Enzymology covers the mechanisms of blood clotting and their role in thrombosis, hemostasis, and many associated ramifications. This book is composed of 12 chapters that consider the integration of knowledge on blood clotting enzymology with hemostasis physiology. The opening chapter deals with the enzymology of the sol-gel transformation was studied in terms of proteins, fats, carbohydrates, surface physics, immunology, biophysical mechanisms, structural architecture, vitamin K and its antagonists, and the rheology of the blood. The subsequent chapters review the biophysical properties and composition of active substance in blood coagulation, as well as the concepts of prothrombin activation. These topics are followed by discussions on the chemical and physicochemical properties of fibrinogen and fibrin; the application of immulogical methods to delineate important properties of plasma constituents; and the mechanisms of antithrombin activity. Other chapters tackle the importance of hirudin and cobra venom for certain experimental laboratory work in the study of the physiology of blood coagulation. The final chapters survey the role of platelets in hemostasis, bleeding disorders, and the chemistry and function of vitamin K in blood coagulation. This book will prove useful to hematologists, enzyme scientist, immunologists, and research workers who are interested in blood coagulation mechanisms.
Author: Walter H. Seegers
Publisher: Academic Press
ISBN: 1483225453
Category : Medical
Languages : en
Pages : 641
Get Book Here
Book Description
Blood Clotting Enzymology covers the mechanisms of blood clotting and their role in thrombosis, hemostasis, and many associated ramifications. This book is composed of 12 chapters that consider the integration of knowledge on blood clotting enzymology with hemostasis physiology. The opening chapter deals with the enzymology of the sol-gel transformation was studied in terms of proteins, fats, carbohydrates, surface physics, immunology, biophysical mechanisms, structural architecture, vitamin K and its antagonists, and the rheology of the blood. The subsequent chapters review the biophysical properties and composition of active substance in blood coagulation, as well as the concepts of prothrombin activation. These topics are followed by discussions on the chemical and physicochemical properties of fibrinogen and fibrin; the application of immulogical methods to delineate important properties of plasma constituents; and the mechanisms of antithrombin activity. Other chapters tackle the importance of hirudin and cobra venom for certain experimental laboratory work in the study of the physiology of blood coagulation. The final chapters survey the role of platelets in hemostasis, bleeding disorders, and the chemistry and function of vitamin K in blood coagulation. This book will prove useful to hematologists, enzyme scientist, immunologists, and research workers who are interested in blood coagulation mechanisms.
Author: Walter Henry Seegers
Publisher:
ISBN:
Category : Blood
Languages : en
Pages : 628
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Book Description
Author: R.F.A. Zwaal
Publisher: Elsevier
ISBN: 0080860729
Category : Science
Languages : en
Pages : 335
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Book Description
This is the first book to give complete insight into the biochemistry of blood coagulation, and demonstrates how this field provides important contributions to fundamental biochemistry, such as enzyme kinetics, lipid-protein interactions, oxidative carboxylation, and cell receptors. The book will be of interest both to biochemists and molecular biologists who want to gain insight into the process of blood coagulation, as well as to those already working in the field of blood coagulation who desire to broaden their insight into its molecular aspects.
Author: Kurt Nikolai Kaulla
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 362
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Book Description
Author: Jarrell D. Bairrington
Publisher:
ISBN:
Category : Blood
Languages : en
Pages : 40
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Book Description
The review cites leading articles which deal directly with the formation of theories of coagulation as they exist today. Many of the papers cited were written because of a search for the cause and cure of hemophilia; therefore, this subject is dealt with in some length. (Author).
Author: Essam Kotb
Publisher: Springer Science & Business Media
ISBN: 3642249809
Category : Medical
Languages : en
Pages : 85
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Book Description
Stress, high blood pressure, smoking, pollution, fast foods, overweight, excessive travelling, surgery, less movement are common features in our modern life. These features are risky for blood clotting disorders. According to WHO, over 29% of the total mortalities worldwide are due to thrombosis. By the year, 2020 cardiovascular diseases (CVDs) may cause an estimated 25 million deaths per year, thus antithrombotic therapy is of great interest. The available thrombolytic agents such as urokinase are highly expensive, antigenic, quite unspecific, pyretogenic and hemorrhagenic. Therefore, the production of fibrinolysing enzymes, which rapidly dissolute thrombi within the vascular tree, without the detriments by microorganisms, as described in this book, is the desirable aim of today’s research.
Author: Holger Schmid-Schönbein
Publisher: Springer Science & Business Media
ISBN: 9780898387049
Category : Medical
Languages : en
Pages : 254
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Book Description
Proceedings of an interdisciplinary meeting, sponsored by the Commission of the European Communities, as advised by the Committee on Medical and Public Health Research
Author: Gertrude E. Perlmann
Publisher: Gulf Professional Publishing
ISBN: 9780121819453
Category : Blood coagulation
Languages : en
Pages : 968
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Book Description
The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.
Author: Nils U. Bang
Publisher: Academic Press
ISBN: 148326128X
Category : Health & Fitness
Languages : en
Pages : 571
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Book Description
Thrombosis and Bleeding Disorders compiles the laboratory and research aspects of thrombosis and hemorrhagic disorders in humans. This book presents reviews of the underlying theory, physiology, and biochemistry of hemostasis and thrombosis, including the enzymology of blood coagulation and fibrinolysis. This compilation is divided into three levels of specific purposes. First is to provide the most reliable and widely accepted laboratory assays of undisputed diagnostic clinical value, which provides newcomers in the field and experienced workers in the coagulation laboratory with a reference manual to everyday work in a clinically-oriented environment. Second is to review and sketch in outline the theoretical sections focusing on mechanisms. Finally, this text aims to include a systematic review of the most successful purification techniques for individual coagulation factors and moieties of the fibrinolytic enzyme system. This publication is beneficial to medical students and clinicians concerned with human blood coagulation.
Author: Torben Halkier
Publisher: Cambridge University Press
ISBN: 9780521381871
Category : Medical
Languages : en
Pages : 488
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Book Description
This book provides a comprehensive account of the proteins involved in blood coagulation, fibrinolysis and the complement system. A major section of the book is devoted to each of these three systems, with separate chapters dealing in detail with structural aspects and different functional processes. Topics covered in the blood coagulation section include the activation of factors IX and X and prothrombin, and the formation and stabilisation of fibrin. The fibrinolysis section includes the activation of plasminogen, the degradation of fibrin and the regulation of fibrinolysis. The complement system itself is covered in chapters dealing with classical activation, alternative activation, the lytic complex and the regulatory processes involved. In addition, one section deals with special topics, including the kinin system, signal peptides, haemostasis, and the evolution of protein structure. This volume will be of use to researchers and advanced students in the fields of haematology, immunology and clinical chemistry.
