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Author: Great Britain. Parliament. House of Commons. Innovation, Universities, Science and Skills Committee
Publisher: The Stationery Office
ISBN: 9780215521248
Category : Science
Languages : en
Pages : 68
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Book Description
Possessing the high containment laboratories necessary to tackle existing and emergent infectious diseases of both humans and animals is of the utmost importance to the UK. A leak of Foot and Mouth disease from such a laboratory at Pirbright in 2007 is the most recent demonstration of how devastating infectious disease can be. It is critical that such an incident does not happen again. This Report outlines a number of shortcomings in the way capacity for high containment research is provided and highlights where the Government should take action. Primarily, the Committee concludes that there is a striking lack of co-ordination between organisations who sponsor and run high containment laboratories. No one organisation or Minister has the remit to maintain a strategic overview of capacity and to co-ordinate these laboratories. There is significant potential for collaboration at a more formal level to assess what facilities are available and make best use of them, identifying any gaps. There is also room for more co-ordination and standardisation of the vetting and training of staff working in this area. The report identifies shortcomings in the funding of high containment facilities, particularly for the significant cost of ongoing maintenance. A number of high containment laboratories have been neglected and the funding situation is uncertain. The Government must ensure that dependable funding is provided to maintain such facilities safely. The new regulatory framework to be introduced in the wake of the Pirbright outbreak is a positive step and should provide a framework in which those operating high containment facilities, given sufficient resources, should be able to continue their work to protect the UK from the threat of infectious disease.
Author: Great Britain. Parliament. House of Commons. Innovation, Universities, Science and Skills Committee
Publisher: The Stationery Office
ISBN: 9780215521248
Category : Science
Languages : en
Pages : 68
Get Book Here
Book Description
Possessing the high containment laboratories necessary to tackle existing and emergent infectious diseases of both humans and animals is of the utmost importance to the UK. A leak of Foot and Mouth disease from such a laboratory at Pirbright in 2007 is the most recent demonstration of how devastating infectious disease can be. It is critical that such an incident does not happen again. This Report outlines a number of shortcomings in the way capacity for high containment research is provided and highlights where the Government should take action. Primarily, the Committee concludes that there is a striking lack of co-ordination between organisations who sponsor and run high containment laboratories. No one organisation or Minister has the remit to maintain a strategic overview of capacity and to co-ordinate these laboratories. There is significant potential for collaboration at a more formal level to assess what facilities are available and make best use of them, identifying any gaps. There is also room for more co-ordination and standardisation of the vetting and training of staff working in this area. The report identifies shortcomings in the funding of high containment facilities, particularly for the significant cost of ongoing maintenance. A number of high containment laboratories have been neglected and the funding situation is uncertain. The Government must ensure that dependable funding is provided to maintain such facilities safely. The new regulatory framework to be introduced in the wake of the Pirbright outbreak is a positive step and should provide a framework in which those operating high containment facilities, given sufficient resources, should be able to continue their work to protect the UK from the threat of infectious disease.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309225752
Category : Political Science
Languages : en
Pages : 216
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Book Description
During July 10-13, 2011, 68 participants from 32 countries gathered in Istanbul, Turkey for a workshop organized by the United States National Research Council on Anticipating Biosecurity Challenges of the Global Expansion of High-containment Biological Laboratories. The United States Department of State's Biosecurity Engagement Program sponsored the workshop, which was held in partnership with the Turkish Academy of Sciences. The international workshop examined biosafety and biosecurity issues related to the design, construction, maintenance, and operation of high-containment biological laboratories- equivalent to United States Centers for Disease Control and Prevention biological safety level 3 or 4 labs. Although these laboratories are needed to characterize highly dangerous human and animal pathogens, assist in disease surveillance, and produce vaccines, they are complex systems with inherent risks. Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories summarizes the workshop discussion, which included the following topics: Technological options to meet diagnostic, research, and other goals; Laboratory construction and commissioning; Operational maintenance to provide sustainable capabilities, safety, and security; and Measures for encouraging a culture of responsible conduct. Workshop attendees described the history and current challenges they face in their individual laboratories. Speakers recounted steps they were taking to improve safety and security, from running training programs to implementing a variety of personnel reliability measures. Many also spoke about physical security, access controls, and monitoring pathogen inventories. Workshop participants also identified tensions in the field and suggested possible areas for action.
Author: Reynolds M. Salerno
Publisher: CRC Press
ISBN: 9780367658823
Category : Biosecurity
Languages : en
Pages : 264
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Book Description
Over the past two decades bioscience facilities worldwide have experienced multiple safety and security incidents, including many notable incidents at so-called sophisticated facilities in North America and Western Europe. This demonstrates that a system based solely on biosafety levels and security regulations may not be sufficient. Setting the stage for a substantively different approach for managing the risks of working with biological agents in laboratories, Laboratory Biorisk Management: Biosafety and Biosecurity introduces the concept of biorisk management--a new paradigm that encompasses both laboratory biosafety and biosecurity. The book also provides laboratory managers and directors with the information and technical tools needed for its implementation. The basis for this new paradigm is a three-pronged, multi-disciplinary model of assessment, mitigation, and performance (the AMP model). The application of the methodologies, criteria, and guidance outlined in the book helps to reduce the risk of laboratories becoming the sources of infectious disease outbreaks. This is a valuable resource for those seeking to embrace and implement biorisk management systems in their facilities and operations, including the biological research, clinical diagnostic, and production/manufacturing communities.
Author: Manfred Weidmann
Publisher: John Wiley & Sons
ISBN: 9783527334674
Category : Science
Languages : en
Pages : 0
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Book Description
The first training manual for new staff working in BSL3/4 labs. This guide is based on a course developed in 2007 by the EU COST action group 28b which serves as a standard for many courses BSL3/4 training courses worldwide. The four-day course consists of lectures and practical training with the lecturers covering all the different possibilities of organising a BSL-3/4 lab including the adaptation to the local requirements of biosafety, safety at work, and social regulations. This book covers bio-containment, hazard criteria and categorisation of microbes, technical specifications of BSL-3 laboratories and ABSL-3 laboratories, personal protective gear, shipping BSL-3 and BSL-4 organisms according to UN and IATA regulations, efficacy of inactivation procedures, fumigation, learning from a history of lab accidents, handling samples that arrive for diagnostic testing and bridging the gap between the requirements of bio-containment and diagnostics. Course participants can not only use the book for their actual training event but it will remain a useful reference throughout their career in BSL3/4 labs.
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9789241546508
Category : Medical
Languages : en
Pages : 196
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Book Description
This is the third edition of this manual which contains updated practical guidance on biosafety techniques in laboratories at all levels. It is organised into nine sections and issues covered include: microbiological risk assessment; lab design and facilities; biosecurity concepts; safety equipment; contingency planning; disinfection and sterilisation; the transport of infectious substances; biosafety and the safe use of recombinant DNA technology; chemical, fire and electrical safety aspects; safety organisation and training programmes; and the safety checklist.
Author: Frank Gottron
Publisher: DIANE Publishing
ISBN: 1437919375
Category : Science
Languages : en
Pages : 33
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Book Description
The fed. gov¿t. responded to the 9/11 terrorist attacks and the subsequent anthrax attacks with increased focus on and funding for biodefense. High-containment labs. (HCL) play a critical role in the biodefense effort, offering the hope of better responses to an attack and a better understanding of the threat posed by bioterrorism. However, they also could increase the risk of a biological attack by serving as a potential source of materials or training. Policymakers have become increasingly interested in the oversight of these facilities following reports of accidents, regulatory noncompliance, and community resistance. A key task for policymakers is to define their goals for enhancing oversight of HCL. Illustrations
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309458889
Category : Science
Languages : en
Pages : 115
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Book Description
The potential misuse of advances in life sciences research is raising concerns about national security threats. Dual Use Research of Concern in the Life Sciences: Current Issues and Controversies examines the U.S. strategy for reducing biosecurity risks in life sciences research and considers mechanisms that would allow researchers to manage the dissemination of the results of research while mitigating the potential for harm to national security.
Author: National Research Council
Publisher: National Academies Press
ISBN: 030914535X
Category : Political Science
Languages : en
Pages : 188
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Book Description
The effort to understand and combat infectious diseases has, during the centuries, produced many key advances in science and medicine-including the development of vaccines, drugs, and other treatments. A subset of this research is conducted with agents that, like anthrax, not only pose a severe threat to the health of humans, plants, and animals but can also be used for ill-intended purposes. Such agents have been listed by the government as biological select agents and toxins. The 2001 anthrax letter attacks prompted the creation of new regulations aimed at increasing security for research with dangerous pathogens. The outcome of the anthrax letter investigation has raised concern about whether these measures are adequate. Responsible Research with Biological Select Agents and Toxins evaluates both the physical security of select agent laboratories and personnel reliability measures designed to ensure the trustworthiness of those with access to biological select agents and toxins. The book offers a set of guiding principles and recommended changes to minimize security risk and facilitate the productivity of research. The book recommends fostering a culture of trust and responsibility in the laboratory, engaging the community in oversight of the Select Agent Program, and enhancing the operation of the Select Agent Program.
Author: World Health Organization
Publisher:
ISBN:
Category : Accidents
Languages : en
Pages : 132
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Book Description
Author: Sam F. Halabi
Publisher: Cambridge University Press
ISBN: 1108484727
Category : Law
Languages : en
Pages : 237
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Book Description
Sharing biological resources-critical for new medicines and vaccines-has declined as countries and scientists dispute rights over research.
