Author: M. R. Ponizovskiy
Publisher:
ISBN: 9781527507111
Category :
Languages : en
Pages : 0
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Book Description
This book advances the knowledge of the mechanism development of a lived organism during its lifetime through the normal stationary state and quasi-stationary pathologic state from the viewpoints of biochemistry, biophysics, and thermodynamics. It explores the possibility of estimating experimental results from the three points of view, giving a broad perspective on the interaction between an organism and its environment. The book also describes the biophysical and biochemical mechanisms' maintenance stability of internal energy according to the First and Second Law of Thermodynamics.
Author: M. R. Ponizovskiy
Publisher: Cambridge Scholars Publishing
ISBN: 1527507122
Category : Medical
Languages : en
Pages : 549
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Book Description
This book advances the knowledge of the mechanism development of a lived organism during its lifetime through the normal stationary state and quasi-stationary pathologic state from the viewpoints of biochemistry, biophysics, and thermodynamics. It explores the possibility of estimating experimental results from the three points of view, giving a broad perspective on the interaction between an organism and its environment. The book also describes the biophysical and biochemical mechanisms’ maintenance stability of internal energy according to the First and Second Law of Thermodynamics.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1424
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Book Description
Author: National Institutes of Health (U.S.). Division of Research Grants
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1212
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Book Description
Author: William Bialek
Publisher: Princeton University Press
ISBN: 1400845572
Category : Science
Languages : en
Pages : 640
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Book Description
Interactions between the fields of physics and biology reach back over a century, and some of the most significant developments in biology--from the discovery of DNA's structure to imaging of the human brain--have involved collaboration across this disciplinary boundary. For a new generation of physicists, the phenomena of life pose exciting challenges to physics itself, and biophysics has emerged as an important subfield of this discipline. Here, William Bialek provides the first graduate-level introduction to biophysics aimed at physics students. Bialek begins by exploring how photon counting in vision offers important lessons about the opportunities for quantitative, physics-style experiments on diverse biological phenomena. He draws from these lessons three general physical principles--the importance of noise, the need to understand the extraordinary performance of living systems without appealing to finely tuned parameters, and the critical role of the representation and flow of information in the business of life. Bialek then applies these principles to a broad range of phenomena, including the control of gene expression, perception and memory, protein folding, the mechanics of the inner ear, the dynamics of biochemical reactions, and pattern formation in developing embryos. Featuring numerous problems and exercises throughout, Biophysics emphasizes the unifying power of abstract physical principles to motivate new and novel experiments on biological systems. Covers a range of biological phenomena from the physicist's perspective Features 200 problems Draws on statistical mechanics, quantum mechanics, and related mathematical concepts Includes an annotated bibliography and detailed appendixes Instructor's manual (available only to teachers)
Author: G. Jean Harry
Publisher: CRC Press
ISBN: 1420054880
Category : Medical
Languages : en
Pages : 334
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Book Description
This new edition presents an integrated approach to neurotoxicology, the study of organisms’ responses to changes in their environment and how interruption of the flow of information by chemical exposure causes a wide range of effects – from learning deficits, sensory disturbances in the extremities, and muscle weakness to seizures and signs similar to neurodegenerative disorders such as Parkinson’s or Alzheimer’s disease. It is an essential resource for understanding the sites and mechanisms of neurotoxicity, for formulating testable hypotheses about the effects of neurotoxicants, and for improving the risk assessment process.
Author: Fritz-Albert Popp
Publisher: Springer Science & Business Media
ISBN: 9401703736
Category : Science
Languages : en
Pages : 499
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Book Description
Most of the specialists working in this interdisciplinary field of physics, biology, biophysics and medicine are associated with "The International Institute of Biophysics" (IIB), in Neuss, Germany, where basic research and possibilities for applications are coordinated. The growth in this field is indicated by the increase in financial support, interest from the scientific community and frequency of publications. Audience: The scientists of IIB have presented the most essential background and applications of biophotonics in these lecture notes in biophysics, based on the summer school lectures by this group. This book is devoted to questions of elementary biophysics, as well as current developments and applications. It will be of interest to graduate and postgraduate students, life scientists, and the responsible officials of industries and governments looking for non-invasive methods of investigating biological tissues.
Author: Jorg Tatzelt
Publisher:
ISBN: 9780954333522
Category : Prions
Languages : en
Pages : 80
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Book Description
A conformational transition of the cellular prion protein (PrPC) into an aberrantly folded isoform designated scrapie prion protein (PrPSc) is the hallmark of a variety of neurodegenerative disorders collectively called prion diseases. They include Creutzfeldt-Jakob disease and Gerstmann-Stäussler-Scheinker syndrome in humans, scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle and chronic wasting disease (CWD) in free-ranging deer. In contrast to the deadly properties of misfolded PrP, PrPC seems to possess a neuroprotective activity. More-over, animal models indicated that the stress-protective activity of PrPC and the neurotoxic effects of PrPSc are somehow interconnected. In this timely book, leading scientists in the field have come together to highlight the apparently incongruous activities of different PrP conformers. The articles outline current research on celluar pathways implicated in the formation and signaling of neurotoxic and physiological PrP isoforms and delineate future research direction. Topics covered include the physiologcial activity of PrPC and its possible role as a neurotrophic factor, the finding that aberrant PrP conformers can cause neurodegeneration in the absence of infectious prion propagation, the requirement of the GPI anchor of PrPC for the neurotoxic effects of scrapie prions, the pathways implicated in the formation and neurotoxic properties of cytosolically localized PrP, the impact of metal ions on the processing of PrP, and the role of autophagy in the propagation and clearance of PrPSc. The book is fully illustrated and chapters include comprehensive reference sections. Essential reading for scientists involved in prion research.
Author:
Publisher:
ISBN:
Category : Toxicology
Languages : en
Pages : 1058
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Book Description
Author: Current Cancer Research Project Analysis Center (U.S.)
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 346
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Book Description
1350 references to research projects being conducted in the United States and elsewhere. Entries arranged under 7 topics, e.g., Control of cell division, Other tumor pathology, and Host response to tumors. Entries include title, researcher, address, contract number, summary, and supporting agency. Indexes by subjects, investigators, contractors, supporting agencies, and contractor numbers.
