Biomolecular Thermodynamics PDF Download
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Author: Douglas Barrick
Publisher: CRC Press
ISBN: 131536302X
Category : Medical
Languages : en
Pages : 553
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Book Description
"an impressive text that addresses a glaring gap in the teaching of physical chemistry, being specifically focused on biologically-relevant systems along with a practical focus.... the ample problems and tutorials throughout are much appreciated." –Tobin R. Sosnick, Professor and Chair of Biochemistry and Molecular Biology, University of Chicago "Presents both the concepts and equations associated with statistical thermodynamics in a unique way that is at visual, intuitive, and rigorous. This approach will greatly benefit students at all levels." –Vijay S. Pande, Henry Dreyfus Professor of Chemistry, Stanford University "a masterful tour de force.... Barrick's rigor and scholarship come through in every chapter." –Rohit V. Pappu, Edwin H. Murty Professor of Engineering, Washington University in St. Louis This book provides a comprehensive, contemporary introduction to developing a quantitative understanding of how biological macromolecules behave using classical and statistical thermodynamics. The author focuses on practical skills needed to apply the underlying equations in real life examples. The text develops mechanistic models, showing how they connect to thermodynamic observables, presenting simulations of thermodynamic behavior, and analyzing experimental data. The reader is presented with plenty of exercises and problems to facilitate hands-on learning through mathematical simulation. Douglas E. Barrick is a professor in the Department of Biophysics at Johns Hopkins University. He earned his Ph.D. in biochemistry from Stanford University, and a Ph.D. in biophysics and structural biology from the University of Oregon.
Author: Douglas Barrick
Publisher: CRC Press
ISBN: 131536302X
Category : Medical
Languages : en
Pages : 553
Get Book Here
Book Description
"an impressive text that addresses a glaring gap in the teaching of physical chemistry, being specifically focused on biologically-relevant systems along with a practical focus.... the ample problems and tutorials throughout are much appreciated." –Tobin R. Sosnick, Professor and Chair of Biochemistry and Molecular Biology, University of Chicago "Presents both the concepts and equations associated with statistical thermodynamics in a unique way that is at visual, intuitive, and rigorous. This approach will greatly benefit students at all levels." –Vijay S. Pande, Henry Dreyfus Professor of Chemistry, Stanford University "a masterful tour de force.... Barrick's rigor and scholarship come through in every chapter." –Rohit V. Pappu, Edwin H. Murty Professor of Engineering, Washington University in St. Louis This book provides a comprehensive, contemporary introduction to developing a quantitative understanding of how biological macromolecules behave using classical and statistical thermodynamics. The author focuses on practical skills needed to apply the underlying equations in real life examples. The text develops mechanistic models, showing how they connect to thermodynamic observables, presenting simulations of thermodynamic behavior, and analyzing experimental data. The reader is presented with plenty of exercises and problems to facilitate hands-on learning through mathematical simulation. Douglas E. Barrick is a professor in the Department of Biophysics at Johns Hopkins University. He earned his Ph.D. in biochemistry from Stanford University, and a Ph.D. in biophysics and structural biology from the University of Oregon.
Author: Urs von Stockar
Publisher: CRC Press
ISBN: 1466582162
Category : Science
Languages : en
Pages : 632
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Book Description
This book covers the fundamentals of the rapidly growing field of biothermodynamics, showing how thermodynamics can best be applied to applications and processes in biochemical engineering. It describes the rigorous application of thermodynamics in biochemical engineering to rationalize bioprocess development and obviate a substantial fraction of this need for tedious experimental work. As such, this book will appeal to a diverse group of readers, ranging from students and professors in biochemical engineering, to scientists and engineers, for whom it will be a valuable reference.
Author: Costas Demetzos
Publisher: Springer
ISBN: 9811309892
Category : Technology & Engineering
Languages : en
Pages : 480
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Book Description
This book highlights the recent advances of thermodynamics and biophysics in drug delivery nanosystems and in biomedical nanodevices. The up-to-date book provides an in-depth knowledge of bio-inspired nanotechnological systems for pharmaceutical applications. Biophysics and thermodynamics, supported by mathematics, are the locomotive by which the drug transportation and the targeting processes will be achieved under the light of the modern pharmacotherapy. They are considered as scientific tools that promote the understanding of physicochemical and thermotropic functionality and behavior of artificial cell membranes and structures like nanoparticulate systems. Therefore, this book focusses on new aspects of biophysics and thermodynamics as important elements for evaluating biomedical nanosystems, and it correlates their physicochemical, biophysical and thermodynamical behaviour with those of a living organism. In 2018, Prof. Demetzos was honored with an award by the Order of Sciences of the Academy of Athens for his scientific contribution in Pharmaceutical Nanotechnology.
Author: Bhavik R. Bakshi
Publisher: Cambridge University Press
ISBN: 113949693X
Category : Technology & Engineering
Languages : en
Pages : 523
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Book Description
This book is a unique, multidisciplinary effort to apply rigorous thermodynamics fundamentals, a disciplined scholarly approach, to problems of sustainability, energy, and resource uses. Applying thermodynamic thinking to problems of sustainable behavior is a significant advantage in bringing order to ill-defined questions with a great variety of proposed solutions, some of which are more destructive than the original problem. The articles are pitched at a level accessible to advanced undergraduates and graduate students in courses on sustainability, sustainable engineering, industrial ecology, sustainable manufacturing, and green engineering. The timeliness of the topic, and the urgent need for solutions make this book attractive to general readers and specialist researchers as well. Top international figures from many disciplines, including engineers, ecologists, economists, physicists, chemists, policy experts and industrial ecologists among others make up the impressive list of contributors.
Author: Luisa Di Paola
Publisher: Springer Nature
ISBN: 3031420225
Category :
Languages : en
Pages : 274
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Book Description
Author: Juan S. Jiménez
Publisher: Cambridge Scholars Publishing
ISBN: 1527556859
Category : Science
Languages : en
Pages : 337
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Book Description
This book is dedicated to studying the thermodynamic bases of the structure-function relationship of proteins. It moves from the elementary principles of physical chemistry to the most current topics of biochemistry, including those that may be subject to some controversy. It considers thermodynamic properties related to the stability and function of proteins from the point of view of physics in a language that, without sacrificing conceptual rigor, is easy to read. Detailing the thermodynamics of protein-ligand interactions, protein naturation, allostery, oxidative phosphorylation and protein phosphorylation, the book will be of interest to students and teachers of chemistry, physics, biochemistry and biotechnology.
Author: Donald Templeton Haynie
Publisher:
ISBN: 9780511649639
Category : SCIENCE
Languages : en
Pages : 440
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Book Description
Emphasising basic concepts and the development of problem-solving skills, this is an introduction to the study of energy transformations for students of the biological sciences. Mathematical complexity is kept to a minimum.
Author: Charles P. Woodbury
Publisher: CRC Press
ISBN: 1420052993
Category : Science
Languages : en
Pages : 272
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Book Description
Macromolecules in the body form noncovalent associations, such as DNA-protein or protein-protein complexes, that control and regulate numerous cellular functions. Understanding how changes in the concentration and conformation of these macromolecules can trigger physiological responses is essential for researchers developing drug therapies to treat
Author: Urs von Stockar
Publisher: CRC Press
ISBN: 1466582170
Category : Science
Languages : en
Pages : 628
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Book Description
This book covers the fundamentals of the rapidly growing field of biothermodynamics, showing how thermodynamics can best be applied to applications and processes in biochemical engineering. It describes the rigorous application of thermodynamics in biochemical engineering to rationalize bioprocess development and obviate a substantial fraction of t
Author: Arieh Y. Ben-Naim
Publisher: Springer Science & Business Media
ISBN: 1475715986
Category : Science
Languages : en
Pages : 700
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Book Description
This book was planned and written with one central goal in mind: to demonstrate that statistical thermodynamics can be used successfully by a broad group of scientists, ranging from chemists through biochemists to biologists, who are not and do not intend to become specialists in statistical thermodynamics. The book is addressed mainly to gradu ate students and research scientists interested in designing experiments the results of which may be interpreted at the molecular level, or in interpreting such experimental results. It is not addressed to those who intend to practice statistical thermodynamics per se. With this goal in mind, I have expended a great deal of effort to make the book clear, readable, and, I hope, enjoyable. This does not necessarily mean that the book as a whole is easy to read. The first four chapters are very detailed. The last four become progressively more difficult to read, for several reasons. First, presuming that the reader has already acquired familiarity with the methods and arguments presented in the first part, I felt that similar arguments could be skipped later on, leaving the details to be filled in by the reader. Second, the systems themselves become progressively more com plicated as we proceed toward the last chapter.
