Biomimetic Radical Chemistry and Applications

Biomimetic Radical Chemistry and Applications PDF Author: Chryssostomos Chatgilialoglu
Publisher: MDPI
ISBN: 3039283928
Category : Technology & Engineering
Languages : en
Pages : 300

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Book Description
The enormous importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted a strong interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment that is suitably designed to be in strict connection with cellular conditions. This Special Issue gives the reader a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to also be used as traces for the discovery of some relevant biological processes. Several subjects are presented, with 12 articles and 6 reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications, and bioinspired synthesis, having “free radicals” as a common denominator.

Biomimetic Radical Chemistry and Applications

Biomimetic Radical Chemistry and Applications PDF Author: Chryssostomos Chatgilialoglu
Publisher: MDPI
ISBN: 3039283928
Category : Technology & Engineering
Languages : en
Pages : 300

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Book Description
The enormous importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted a strong interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment that is suitably designed to be in strict connection with cellular conditions. This Special Issue gives the reader a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to also be used as traces for the discovery of some relevant biological processes. Several subjects are presented, with 12 articles and 6 reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications, and bioinspired synthesis, having “free radicals” as a common denominator.

Membrane Lipidomics for Personalized Health

Membrane Lipidomics for Personalized Health PDF Author: Carla Ferreri
Publisher: John Wiley & Sons
ISBN: 1118540417
Category : Science
Languages : en
Pages : 204

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Book Description
Lipidomics is an important aspect of personalized medicine in relation to nutrition and metabolism. This approach has become important due to the substantial presence of nutraceuticals in the market, since it gives personalized criteria on how to choose the right nutraceutical strategy for both prevention and for quality of life. This multi-disciplinary textbook uses a simple and practical approach to provide a comprehensive overview of lipidomics and their connection with health and nutrition. The text is divided into two parts: - Part 1 outlines the basics of lipidomics and focuses on the biochemical and nutritional aspects with descriptions of the analytical methods employed for the examination of cell membrane fatty acid composition. - Part 2 familiarizes the reader with the use of membrane lipidomic diagnostics in practical health care, using health conditions as examples to introduce the concept of lipidomic profiles in different physiological and pathological situations including prevention. Through the various properties of membrane lipidomics, readers will be able to combine the molecular status of the cell membrane with the evaluation of the subject for personalized nutritional and nutraceutical strategies. Membrane Lipidomics for Personalized Health will be beneficial to biologists, biochemists and medical researchers, as well as health care professionals, pharmacists, and nutritionists seeking in-depth information on the topic.

Organosilanes in Radical Chemistry

Organosilanes in Radical Chemistry PDF Author: Chryssostomos Chatgilialoglu
Publisher: John Wiley & Sons
ISBN: 0470094257
Category : Science
Languages : en
Pages : 240

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Book Description
In recent years silicon-centered radicals have played an important role in organic synthesis, polymer chemistry and material sciences. The aim of this book is to offer for the first time a description of silyl radicals within an interdisciplinary context, connecting structural characteristics and chemical properties to their application in different areas of chemistry. The first time different aspects of silyl radicals have been brought together Excellent reference tool for experienced practitioners of radical and/or silicon chemistry Presents various aspects of these intermediates in an original, comprehensive fashion This book is essential for anyone working in free radical and/or silicon chemistry as well as for those who want to approach these fields for the first time.

Non-covalent Interactions in the Synthesis and Design of New Compounds

Non-covalent Interactions in the Synthesis and Design of New Compounds PDF Author: Abel M. Maharramov
Publisher: John Wiley & Sons
ISBN: 1119113857
Category : Science
Languages : en
Pages : 481

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Book Description
This book aims to overview the role of non-covalent interactions, such as hydrogen and halogen bonding, π-π, π-anion and electrostatic interactions, hydrophobic effects and van der Waals forces in the synthesis of organic and inorganic compounds, as well as in design of new crystals and function materials. The proposed book should allow to combine, in a systematic way, recent advances on the application of non-covalent interactions in synthesis and design of new compounds and functional materials with significance in Inorganic, Organic, Coordination, Organometallic, Pharmaceutical, Biological and Material Chemistries. Therefore, it should present a multi- and interdisciplinary character assuring a rather broad scope. We believe it will be of interest to a wide range of academic and research staff concerning the synthesis of new compounds, catalysis and materials. Each chapter will be written by authors who are well known experts in their respective fields.

Robotics—Advances in Research and Application: 2013 Edition

Robotics—Advances in Research and Application: 2013 Edition PDF Author:
Publisher: ScholarlyEditions
ISBN: 1481692186
Category : Technology & Engineering
Languages : en
Pages : 552

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Book Description
Robotics—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Autonomous Robotics. The editors have built Robotics—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Autonomous Robotics in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Robotics—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Biomimetics

Biomimetics PDF Author: Ziyad S. Haidar
Publisher:
ISBN: 9781803568980
Category : Biomimetics
Languages : en
Pages : 0

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Book Description


Stereoselective Synthesis of Drugs and Natural Products

Stereoselective Synthesis of Drugs and Natural Products PDF Author: Vasyl Andrushko
Publisher: John Wiley & Sons
ISBN: 1118628330
Category : Science
Languages : en
Pages : 1836

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Book Description
Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.

Bioadhesion and Biomimetics

Bioadhesion and Biomimetics PDF Author: Havazelet Bianco-Peled
Publisher: CRC Press
ISBN: 981446399X
Category : Medical
Languages : en
Pages : 310

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Book Description
Bioadhesion is often defined as the state in which two materials, at least one of which is biological in nature, are held together for extended periods of time by interfacial forces. It is an area of active multidisciplinary research, where engineers, scientists-including chemists, physicists, biologists, and medical experts-materials' producers, a

Streamlining Free Radical Green Chemistry

Streamlining Free Radical Green Chemistry PDF Author: V. Tamara Perchyonok
Publisher: Royal Society of Chemistry
ISBN: 1849733325
Category : Science
Languages : en
Pages : 804

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Book Description
This practical, concise guide showcases the sustainable methods offered by green free radical chemistry and summarizes the fundamental science involved.

Advances in Biomimetics

Advances in Biomimetics PDF Author: Anne George
Publisher: BoD – Books on Demand
ISBN: 9533071915
Category : Medical
Languages : en
Pages : 536

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Book Description
The interaction between cells, tissues and biomaterial surfaces are the highlights of the book "Advances in Biomimetics". In this regard the effect of nanostructures and nanotopographies and their effect on the development of a new generation of biomaterials including advanced multifunctional scaffolds for tissue engineering are discussed. The 2 volumes contain articles that cover a wide spectrum of subject matter such as different aspects of the development of scaffolds and coatings with enhanced performance and bioactivity, including investigations of material surface-cell interactions.