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Author: S. Andersson
Publisher: Elsevier
ISBN: 0080528074
Category : Mathematics
Languages : en
Pages : 535
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Book Description
This book presents new mathematics for the description of structure and dynamics in molecular and cellular biology. On an exponential scale it is possible to combine functions describing inner organisation, including finite periodicity, with functions for outside morphology into a complete definition of structure. This mathematics is particularly fruitful to apply at molecular and atomic distances. The structure descriptions can then be related to atomic and molecular forces and provide information on structural mechanisms. The calculations have been focussed on lipid membranes forming the surface layers of cell organelles. Calculated surfaces represent the mid-surface of the lipid bilayer. Membrane dynamics such as vesicle transport are described in this new language. Periodic membrane assemblies exhibit conformations based on the standing wave oscillations of the bilayer, considered to reflect the true dynamic nature of periodic membrane structures. As an illustration the structure of an endoplasmatic reticulum has been calculated. The transformation of such cell membrane assemblies into cubosomes seems to reflect a transition into vegetative states. The organisation of the lipid bilayer of nerve cells is analyzed, taking into account an earlier observed lipid bilayer phase transition associated with the depolarisation of the membrane. Evidence is given for a new structure of the alveolar surface, relating the mathematical surface defining the bilayer organisation to new experimental data. The surface layer is proposed to consist of a coherent phase, consisting of a lipid-protein bilayer curved according to a classical surface - the CLP surface. Without employing this new mathematics it would not be possible to give an analytical description of this structure and its deformation during the respiration cycle. In more general terms this mathematics is applied to the description of the structure and dynamic properties of motor proteins, cytoskeleton proteins, and RNA/DNA. On a macroscopic scale the motions of cilia, sperm and flagella are modelled. This mathematical description of biological structure and dynamics, biomathematics, also provides significant new information in order to understand the mechanisms governing shape of living organisms.
Author: S. Andersson
Publisher: Elsevier
ISBN: 0080528074
Category : Mathematics
Languages : en
Pages : 535
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Book Description
This book presents new mathematics for the description of structure and dynamics in molecular and cellular biology. On an exponential scale it is possible to combine functions describing inner organisation, including finite periodicity, with functions for outside morphology into a complete definition of structure. This mathematics is particularly fruitful to apply at molecular and atomic distances. The structure descriptions can then be related to atomic and molecular forces and provide information on structural mechanisms. The calculations have been focussed on lipid membranes forming the surface layers of cell organelles. Calculated surfaces represent the mid-surface of the lipid bilayer. Membrane dynamics such as vesicle transport are described in this new language. Periodic membrane assemblies exhibit conformations based on the standing wave oscillations of the bilayer, considered to reflect the true dynamic nature of periodic membrane structures. As an illustration the structure of an endoplasmatic reticulum has been calculated. The transformation of such cell membrane assemblies into cubosomes seems to reflect a transition into vegetative states. The organisation of the lipid bilayer of nerve cells is analyzed, taking into account an earlier observed lipid bilayer phase transition associated with the depolarisation of the membrane. Evidence is given for a new structure of the alveolar surface, relating the mathematical surface defining the bilayer organisation to new experimental data. The surface layer is proposed to consist of a coherent phase, consisting of a lipid-protein bilayer curved according to a classical surface - the CLP surface. Without employing this new mathematics it would not be possible to give an analytical description of this structure and its deformation during the respiration cycle. In more general terms this mathematics is applied to the description of the structure and dynamic properties of motor proteins, cytoskeleton proteins, and RNA/DNA. On a macroscopic scale the motions of cilia, sperm and flagella are modelled. This mathematical description of biological structure and dynamics, biomathematics, also provides significant new information in order to understand the mechanisms governing shape of living organisms.
Author:
Publisher: Krishna Prakashan Media
ISBN: 9788182830257
Category :
Languages : en
Pages : 252
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Book Description
Author: Raina Robeva
Publisher: Academic Press
ISBN: 0080550991
Category : Mathematics
Languages : en
Pages : 466
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Book Description
Essential for all biology and biomathematics courses, this textbook provides students with a fresh perspective of quantitative techniques in biology in a field where virtually any advance in the life sciences requires a sophisticated mathematical approach. An Invitation to Biomathematics, expertly written by a team of experienced educators, offers students a solid understanding of solving biological problems with mathematical applications. This text succeeds in enabling students to truly experience advancements made in biology through mathematical models by containing computer-based hands-on laboratory projects with emphasis on model development, model validation, and model refinement. The supplementary work, Laboratory Manual of Biomathematics is available separately ISBN 0123740223, or as a set ISBN: 0123740290) - Provides a complete guide for development of quantification skills crucial for applying mathematical methods to biological problems - Includes well-known examples from across disciplines in the life sciences including modern biomedical research - Explains how to use data sets or dynamical processes to build mathematical models - Offers extensive illustrative materials - Written in clear and easy-to-follow language without assuming a background in math or biology - A laboratory manual is available for hands-on, computer-assisted projects based on material covered in the text
Author: L.M. Ricciardi
Publisher: Springer Science & Business Media
ISBN: 9400929757
Category : Mathematics
Languages : en
Pages : 719
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Book Description
Biomathematics emerged and rapidly grew as an independent discipline in the late sixties as scientists with various backgrounds in the mathematical, biological and physical sciences gathered together to form Departments and Institutes centered around this discipline that many at that time felt should fall between the cracks of legitimate science. For various reasons some of these new institutions vanished in the mid-seventies, particularly in the U. S. , the main reason for their demise being economic. Nevertheless, good biomathematical so that the range research has been ceaselessly carried on by numerous workers worldwide of this activity appears now as truly impressive: from useful and effective mathematical statements about problems that are firmly rooted in the 'wet' reality of biology to deep theoretical investigations on outstanding basic questions. It is also interesting to take note that some ideas and theories set forth by 'paleo-biomathematicians' almost a quarter of century ago are now becoming highly appreciated also by scientists engaged in quite different research fields. For instance, neural nets is the hot topic in computer science these days! Well aware of the growing interest in this relatively new field, years back I organized a small workshop on Biomathematics: Current Status and Future Perspectives which was held at the University of Salerno during the middle of April, 1980.
Author:
Publisher: Elsevier
ISBN: 0080871690
Category : Mathematics
Languages : en
Pages : 313
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Book Description
Biomathematics in 1980
Author: Laécio Carvalho de Barros
Publisher: Springer
ISBN: 3662533243
Category : Technology & Engineering
Languages : en
Pages : 304
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Book Description
This book provides an essential introduction to the field of dynamical models. Starting from classical theories such as set theory and probability, it allows readers to draw near to the fuzzy case. On one hand, the book equips readers with a fundamental understanding of the theoretical underpinnings of fuzzy sets and fuzzy dynamical systems. On the other, it demonstrates how these theories are used to solve modeling problems in biomathematics, and presents existing derivatives and integrals applied to the context of fuzzy functions. Each of the major topics is accompanied by examples, worked-out exercises, and exercises to be completed. Moreover, many applications to real problems are presented. The book has been developed on the basis of the authors’ lectures to university students and is accordingly primarily intended as a textbook for both upper-level undergraduates and graduates in applied mathematics, statistics, and engineering. It also offers a valuable resource for practitioners such as mathematical consultants and modelers, and for researchers alike, as it may provide both groups with new ideas and inspirations for projects in the fields of fuzzy logic and biomathematics.
Author: István Bán
Publisher: Elsevier Publishing Company
ISBN:
Category : Mathematics
Languages : en
Pages : 212
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Book Description
Author: Simon A. Levin
Publisher: Springer Science & Business Media
ISBN: 3642501249
Category : Mathematics
Languages : en
Pages : 637
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Book Description
From a mathematical point of view, physiologically structured population models are an underdeveloped branch of the theory of infinite dimensional dynamical systems. We have called attention to four aspects: (i) A choice has to be made about the kind of equations one extracts from the predominantly verbal arguments about the basic assumptions, and subsequently uses as a starting point for a rigorous mathematical analysis. Though differential equations are easy to formulate (different mechanisms don't interact in infinites imal time intervals and so end up as separate terms in the equations) they may be hard to interpret rigorously as infinitesimal generators. Integral equations constitute an attractive alternative. (ii) The ability of physiologically structured population models to increase our un derstanding of the relation between mechanisms at the i-level and phenomena at the p-level will depend strongly on the development of dynamical systems lab facilities which are applicable to this class of models. (iii) Physiologically structured population models are ideally suited for the for mulation of evolutionary questions. Apart from the special case of age (see Charlesworth 1980, Yodzis 1989, Caswell 1989, and the references given there) hardly any theory exists at the moment. This will, hopefully, change rapidly in the coming years. Again the development of appropriate software may turn out to be crucial.
Author: Mostafa Bachar
Publisher: Springer
ISBN: 3642321577
Category : Mathematics
Languages : en
Pages : 216
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Book Description
Stochastic biomathematical models are becoming increasingly important as new light is shed on the role of noise in living systems. In certain biological systems, stochastic effects may even enhance a signal, thus providing a biological motivation for the noise observed in living systems. Recent advances in stochastic analysis and increasing computing power facilitate the analysis of more biophysically realistic models, and this book provides researchers in computational neuroscience and stochastic systems with an overview of recent developments. Key concepts are developed in chapters written by experts in their respective fields. Topics include: one-dimensional homogeneous diffusions and their boundary behavior, large deviation theory and its application in stochastic neurobiological models, a review of mathematical methods for stochastic neuronal integrate-and-fire models, stochastic partial differential equation models in neurobiology, and stochastic modeling of spreading cortical depression.
Author: J. C. Misra
Publisher: World Scientific
ISBN: 9812774858
Category : Science
Languages : en
Pages : 525
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Book Description
This book on modelling and simulation in biomathematics will be invaluable to researchers who are interested in the emerging areas of the field. Graduate students in related areas as well as lecturers will also find it beneficial. Some of the chapters have been written by distinguished experts in the field. Sample Chapter(s). Chapter 1: Detecting Mosaic Structures in DNA Sequence Alignments (1,349 KB). Contents: Detecting Mosaic Structures in DNA Sequence Alignments (D Husmeier); Application of Statistical Methodology and Model Design to Socio-Behaviour of HIV Transmission (J Oluwoye); A Stochastic Model Incorporating HIV Treatments for a Heterosexual Population: Impact on Threshold Conditions (R J Gallop et al.); Modeling and Identification of the Dynamics of the MF-Influenced Free-Radical Transformations in Lipid-Modeling Substances and Lipids (J Bentsman et al.); Computer Simulation of Self-Reorganization in Biological Cells (D Greenspan); Modelling Biological Gel Contraction by Cells: Consequences of Cell Traction Forces Distribution and Initial Stress (S Ramtani); Peristaltic Transport of Physiological Fluids (J C Misra & S K Pandey); Mathematical Modelling of DNA Knots and Links (J C Misra & S Mukherjee); Using Monodomain Computer Models for the Simulation of Electric Fields During Excitation Spread in Cardiac Tissue (G Plank); Flow in Tubes with Complicated Geometries with Special Application to Blood Flow in Large Arteries (G Jayaraman); Mathematical Modeling in Reproductive Biomedicine (S Sharma & S K Guha); Image Theory and Applications in Bioelectromagnetics (P D Einziger et al.); Dynamics of Humanoid Robots: Geometrical and Topological Duality (V G Ivancevic); The Effects of Body Composition on Energy Expenditure and Weight Dynamics During Hypophagia: A Setpoint Analysis (F P Kozusko); Mathematical Models in Population Dynamics and Ecology (R Diluo); Modelling in Bone Biomechanics (J C Misra & S Samanta). Readership: Graduate students, academic and researchers in biomathematics, mathematical biology, mathematical modeling, biotechnology, biocomputing, biophysics, bioengineering and mechanics."
