Biomarkers in Leishmaniasis PDF Download
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Author: Javier Moreno
Publisher: Frontiers Media SA
ISBN: 288963339X
Category :
Languages : en
Pages : 232
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Book Description
Author: Javier Moreno
Publisher: Frontiers Media SA
ISBN: 288963339X
Category :
Languages : en
Pages : 232
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Book Description
Author: Mukesh Samant
Publisher: Academic Press
ISBN: 0128227982
Category : Medical
Languages : en
Pages : 281
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Book Description
Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis. - Provides an overview Leishmania and leishmanisis which include its history, transmission, clinical picture, and treatment - Discusses novel approaches to study parasite infection and treatment - Explores recent advances in the development of diagnostic kits, drug development and various vaccination strategies
Author: Ghousia Begum
Publisher: BoD – Books on Demand
ISBN: 1789236665
Category : Medical
Languages : en
Pages : 250
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Book Description
This book investigates the emerging use of biomarkers as a diagnostic tool for the identification of patients with an abnormal condition or as a tool for staging the extent of disease, as an indicator of disease prognosis. Chapters in Part I focus on biomarkers for cancer, including breast cancer and pancreatic cancer, as well as circulating microRNA profiling in cancer biomarker discovery. Chapters in Part II focus on biomarkers of other diagnoses/diseases, including sepsis, childhood renal diseases, pulmonary diseases, Alzheimer's, leishmaniasis, and heart failure. This book investigates the emerging use of biomarkers as a diagnostic tool for the identification of patients with an abnormal condition or as a tool for staging the extent of disease, as an indicator of diseases prognosis. The book is of considerable importance for a broad range of people including researchers, clinicians, and university students.
Author: Stefan Offermanns
Publisher: Springer Science & Business Media
ISBN: 3540389164
Category : Medical
Languages : en
Pages : 1515
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Book Description
An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.
Author: Alicia Ponte-Sucre
Publisher: Springer Science & Business Media
ISBN: 3709111250
Category : Medical
Languages : en
Pages : 458
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Book Description
One of the main problems concerning therapeutic tools for the treatment of parasitic diseases, including leishmaniasis, is that some field parasites are naturally resistant to the classical drugs; additionally, current therapies may select parasites prone to be resistant to the applied drugs. These features are (at least partially) responsible for the disappointing persistence of the disease and resultant deaths worldwide. This book provides a comprehensive view of the pathology of the disease itself, and of parasitic drug resistance, its molecular basis, consequences and possible treatments. Scientists both from academic fields and from the industry involved in biomedical research and drug design, will find in this book a valuable and fundamental guide that conveys the knowledge needed to understand and to improve the success in combating this disease worldwide.
Author: Clara Saldarriaga
Publisher: Academic Press
ISBN: 0323911234
Category : Science
Languages : en
Pages : 290
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Book Description
Neglected Tropical Diseases and other Infectious Diseases Affecting the Heart provides a comprehensive and systematic review on the literature surrounding Neglected Tropical Diseases and infectious diseases and how they affect the heart. Written by Emerging Leaders of the Interamerican Society of Cardiology (SIAC), the book includes the latest research findings, covering the cardiac involvement of a range of viral, bacterial and parasitic diseases, including COVID19, HIV, Zika, Lyme Disease, and more. Chapters cover epidemiology, the physiopathology of cardiovascular involvement, symptoms, diagnosis, and treatment options for each disease, making the book suitable to researchers, scientists, clinicians and physicians in the field. - Covers the cardiac involvement of a range of viral, bacterial and parasitic diseases, including COVID19, HIV, Influenza, Lyme Disease, and more - Explains the diagnosis and management of cardiovascular ailments in neglected tropical diseases - Written in an easy to read manner with figures, illustrations and tables to aid understanding - Contains chapter formatted with an Introduction, Epidemiology, Physiopathology of Cardiovascular (CV) involvement, Symptoms, Diagnosis, Treatment, Discussion and Conclusions
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309091594
Category : Social Science
Languages : en
Pages : 469
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Book Description
The U.S. military's concerns about the individual combat service member's ability to avoid performance degradation, in conjunction with the need to maintain both mental and physical capabilities in highly stressful situations, have led to and interest in developing methods by which commanders can monitor the status of the combat service members in the field. This report examines appropriate biological markers, monitoring technologies currently available and in need of development, and appropriate algorithms to interpret the data obtained in order to provide information for command decisions relative to the physiological "readiness" of each combat service member. More specifically, this report also provides responses to questions posed by the military relative to monitoring the metabolic regulation during prolonged, exhaustive efforts, where nutrition/hydration and repair mechanisms may be mismatched to intakes and rest, or where specific metabolic derangements are present.
Author: Gauri Misra
Publisher: Academic Press
ISBN: 0128213973
Category : Science
Languages : en
Pages : 156
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Book Description
Molecular Advancements in Tropical Diseases Drug Discovery presents in-depth knowledge relating to the detection of infection, epidemiology, drugs against various tropical diseases, new target sites for drug discovery and multidrug resistance issues using bioinformatics tools and approaches. The book's chapters are written by experts in their respective fields so that each disease is covered in a rational manner and with a solid foundation on existing facts and prospective research ideas. - Updates knowledge about tropical diseases with recent advancements in the field - Presents an overview of new research covering detection, infection, epidemiology and risk factors of the most common tropical diseases using bioinformatics tools - Encompasses a detailed description of developments in drug discovery, new drugs and their molecular mechanisms of action
Author: Fernando Cobo
Publisher: Elsevier
ISBN: 1908818735
Category : Medical
Languages : en
Pages : 299
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Book Description
The increase of immigrant population in developed countries (mainly in Europe and North America) together with an important increase of international travel worldwide are the two most important causes that have contributed to the introduction and diagnosis of imported/tropical infectious diseases in these countries. These factors have had an important impact in developed countries in both social and economic aspects. Imported Infectious Diseases focuses not only on describing the infections, but also in evaluating the current epidemiology, the economic and social impact and the possibility to apply immunization measures and vaccines. The main purpose of this book is to give an overview of the current most important and frequent imported infectious diseases in developed countries. The first chapter informs about the medical services that are being offered to the immigrants in the main developed countries depending on the legal situation. Following chapters describe the main surveillance systems for these kinds of diseases, mainly in Europe and North America. Finally, remaining chapters contain sections on epidemiology, pathogenesis, clinical features, diagnosis, treatment and prevention.
Author: Farhat Afrin
Publisher: BoD – Books on Demand
ISBN: 1789841011
Category : Medical
Languages : en
Pages : 234
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Book Description
Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furthermore, to strengthen the leishmaniasis elimination drive, particular emphasis has to be laid on identification of new targets and vaccination strategies. This book gives a brief glimpse of the epidemiology of leishmaniasis, immune evasion, vaccination, and therapeutic modalities that may work by untangling the immunological cross-wires of pathogenic cross-talk. The Conventional treatment and its drawbacks, the prospects of phytotherapy and nanomedicines, are also discussed. The identification of drug targets with the aim of designing inhibitors is also exemplified.
