The Biology of the Autistic Syndromes

The Biology of the Autistic Syndromes PDF Author: Christopher Gillberg
Publisher: Cambridge University Press
ISBN: 9781898683223
Category : Medical
Languages : en
Pages : 348

Get Book Here

Book Description
Autism is not a single disease but a syndrome of different diseases. In this completely reworked and updated third edition, two world authorities, Christopher Gillberg and Mary Coleman, address the difficulties this presents for clinical diagnosis with diagnostic aids and clear guidelines for medical evaluation. Epidemiology, neuropsychological studies and behavior complexes, such as self-injury, are reviewed in detail, and the authors give a detailed explanation of what is known about the molecular biology and genetics of autism. Epilepsy and electrophysiological studies are also covered, as well as biochemistry, endocrinology, immunology, brain imaging and neuropathology. The available medical therapies are reviewed, along with an update on what is known about other interventions, such as psychoeducational and behavioral modification procedures. The book concludes with an integration of current knowledge from diverse fields. This is an essential text for clinicians and will also be of interest to parents of autistic children.

The Biology of the Autistic Syndromes

The Biology of the Autistic Syndromes PDF Author: Christopher Gillberg
Publisher: Cambridge University Press
ISBN: 9781898683223
Category : Medical
Languages : en
Pages : 348

Get Book Here

Book Description
Autism is not a single disease but a syndrome of different diseases. In this completely reworked and updated third edition, two world authorities, Christopher Gillberg and Mary Coleman, address the difficulties this presents for clinical diagnosis with diagnostic aids and clear guidelines for medical evaluation. Epidemiology, neuropsychological studies and behavior complexes, such as self-injury, are reviewed in detail, and the authors give a detailed explanation of what is known about the molecular biology and genetics of autism. Epilepsy and electrophysiological studies are also covered, as well as biochemistry, endocrinology, immunology, brain imaging and neuropathology. The available medical therapies are reviewed, along with an update on what is known about other interventions, such as psychoeducational and behavioral modification procedures. The book concludes with an integration of current knowledge from diverse fields. This is an essential text for clinicians and will also be of interest to parents of autistic children.

Cellular and Molecular Biology of Autism Spectrum Disorders

Cellular and Molecular Biology of Autism Spectrum Disorders PDF Author: Anna Strunecká
Publisher: Bentham Science Publishers
ISBN: 160805196X
Category : Science
Languages : en
Pages : 232

Get Book Here

Book Description
"Over the past several decades the incidence of autism spectrum disorders (ASD) has increased dramatically. The etiology of ASD remains an unsolved puzzle to scientists, physicians, pediatricians, psychiatrists, and pharmacologists. Our E-book will address"

A Time for Metabolism and Hormones

A Time for Metabolism and Hormones PDF Author: Paolo Sassone-Corsi
Publisher: Springer
ISBN: 3319270699
Category : Medical
Languages : en
Pages : 141

Get Book Here

Book Description
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

Autism Spectrum Disorders

Autism Spectrum Disorders PDF Author: Andreas M. Grabrucker
Publisher:
ISBN:
Category :
Languages : en
Pages : 117

Get Book Here

Book Description
Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.

Autism Spectrum Disorders

Autism Spectrum Disorders PDF Author: Stephen Deutsch
Publisher: BoD – Books on Demand
ISBN: 9533074957
Category : Science
Languages : en
Pages : 214

Get Book Here

Book Description
Estimated prevalence rates of autism spectrum disorders (ASDs) have increased at an alarming rate over the past decade; current estimates stand as high as 1 in 110 persons in the population with a higher ratio of affected males to females. In addition to their emotional impact on the affected persons and their family members (in fact, the latter are often unrecognized unaffected “patients” themselves), the economic and social impacts of ASDs on society are staggering. Persons with ASDs will need interdisciplinary approaches to complex treatment and life planning, including, but not limited to, special education, speech and language therapy, vocational skills training and rehabilitation, social skills training and cognitive remediation, in addition to pharmacotherapy. The current book highlights some of the recent research on nosology, etiology, and pathophysiology. Additionally, the book touches on the implications of new research for treatment and genetic counseling. Importantly, because the field is advancing rapidly, no book can be considered the final word or finished product; thus, the availability of open access rapid publication is a mechanism that will help to assure that readers remain current and up-to-date.

Homeostatic Control of Brain Function

Homeostatic Control of Brain Function PDF Author: Detlev Boison
Publisher: Oxford University Press
ISBN: 0199322295
Category : Medical
Languages : en
Pages : 657

Get Book Here

Book Description
Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include · A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. · Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. · Incorporation of homeostatic therapies into existing basic and clinical research paradigms. · Extensive scientific basic and clinical research ranging from molecules to disorders. · Emerging practical information for improving homeostasis. · Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.

Autism and Asperger Syndrome

Autism and Asperger Syndrome PDF Author: Simon Baron-Cohen
Publisher: Oxford University Press
ISBN: 019850490X
Category : Family & Relationships
Languages : en
Pages : 170

Get Book Here

Book Description
"In this book Simon Baron-Cohen summarizes the current understanding of autism and Asperger Syndrome. He explains the process of diagnosis, as well as the options for education and intervention for those with these conditions. Taking a lifespan approach, Professor Baron-Cohen considers how the conditions affect very young children through to adulthood. He also outlines his new Empathizing-Systemizing (ES) theory, which aims to explain all of the psychological features of autistic-spectrum conditions." "This book is designed firstly for people with these conditions and their families. It will be useful to clinicians, teachers, and other professionals involved in the care and support of people on the autistic-spectrum. The book will also provide an introduction to the topic for students in the social and biological sciences."--BOOK JACKET.

Diagnostic and Statistical Manual of Mental Disorders (DSM-5)

Diagnostic and Statistical Manual of Mental Disorders (DSM-5) PDF Author: American Psychiatric Association
Publisher: American Psychiatric Publishing
ISBN: 9781955245180
Category :
Languages : en
Pages :

Get Book Here

Book Description


Mitochondrial Dysfunction

Mitochondrial Dysfunction PDF Author: Lawrence H. Lash
Publisher: Elsevier
ISBN: 1483218619
Category : Science
Languages : en
Pages : 527

Get Book Here

Book Description
Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

Defining Autism

Defining Autism PDF Author: Emily L. Casanova
Publisher: Jessica Kingsley Publishers
ISBN: 1784503495
Category : Psychology
Languages : en
Pages : 266

Get Book Here

Book Description
Offering a summary of the current state of knowledge in autism research, Defining Autism looks at the different genetic, neurological and environmental causes of, and contributory factors to autism. It takes a wide-ranging view of developmental and genetic factors, and considers autism's relationship with other conditions such as epilepsy. Shedding light on the vast number of autism-related syndromes which are all too often denied adequate attention, it shows how, whilst autism refers to a single syndrome, it can be understood as many different conditions, with the common factors being biological, rather than behavioral.