Mineral Fibers and Health

Mineral Fibers and Health PDF Author: F.D.K. Liddell
Publisher: CRC Press
ISBN: 9780849366468
Category : Science
Languages : en
Pages : 398

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Book Description
The part of this book covering pathogensis and modes of action begins with a chapter on the physicochemical properties of asbestos fibers and a chapter on the deposition and retention of fibers within the lung and their clearance. Some of the effects of asbestos can be reproduced in animal experiments, and the book includes a full review of the results from animal studies using various routes of administration of fibers. It is also generally accepted that the effects of fibers on pulmonary macrophages is central to all fiber-induced pathology, and the release of macrophage-associated inflammatory and immunological mediatros is dealt with in a further chapter. Examination of pathogenicity by cell culture is described, and areas covered include the role of free radicals and cellular mechanisms in producing genetic damage. The fiber-induced activation of some second messenger pathways is also described, with consideration of whether or not similar cellular mechanisms are responsible for all the clinical conditions associated with fiber exposure. Knowledge of the mechanisms involved should be valuable in the development of safe fibers and the prevention of human exposure to new materials that are dangerous as asbestos. The final chapters expound and resolve the conflicts in evidence, discuss the importance of fibers for human well-being and the possible health impact on nonmineral alternatives, and evaluate risks to the public

Mineral Fibers and Health

Mineral Fibers and Health PDF Author: F.D.K. Liddell
Publisher: CRC Press
ISBN: 9780849366468
Category : Science
Languages : en
Pages : 398

Get Book Here

Book Description
The part of this book covering pathogensis and modes of action begins with a chapter on the physicochemical properties of asbestos fibers and a chapter on the deposition and retention of fibers within the lung and their clearance. Some of the effects of asbestos can be reproduced in animal experiments, and the book includes a full review of the results from animal studies using various routes of administration of fibers. It is also generally accepted that the effects of fibers on pulmonary macrophages is central to all fiber-induced pathology, and the release of macrophage-associated inflammatory and immunological mediatros is dealt with in a further chapter. Examination of pathogenicity by cell culture is described, and areas covered include the role of free radicals and cellular mechanisms in producing genetic damage. The fiber-induced activation of some second messenger pathways is also described, with consideration of whether or not similar cellular mechanisms are responsible for all the clinical conditions associated with fiber exposure. Knowledge of the mechanisms involved should be valuable in the development of safe fibers and the prevention of human exposure to new materials that are dangerous as asbestos. The final chapters expound and resolve the conflicts in evidence, discuss the importance of fibers for human well-being and the possible health impact on nonmineral alternatives, and evaluate risks to the public

Man-made Vitreous Fibres

Man-made Vitreous Fibres PDF Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher: World Health Organization
ISBN: 9283212819
Category : Medical
Languages : en
Pages : 434

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Book Description
"This publication represents the views and expert opinions of an IARC working group on the evaluation of carcinogenic risks to humans, which met in Lyon, 9-16 October 2001."

Biological Effects of Man-made Mineral Fibres

Biological Effects of Man-made Mineral Fibres PDF Author:
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 168

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Book Description


Asbestiform Fibers

Asbestiform Fibers PDF Author: Committee on Nonoccupational Health Risks of Asbestiform Fibers
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 356

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Book Description
Much of the more than 30 million tons of asbestos used in the United States since 1900 is still present as insulation in offices and schools, as vinyl-asbestos flooring in homes, and in other common products. This volume presents a comprehensive evaluation of the relation of these fibers to specific diseases and the extent of nonoccupational risks associated with them. It covers sources of asbestiform fibers, properties of the fibers, and carcinogenic and fibrogenic risks they pose.

Environmental Toxicants

Environmental Toxicants PDF Author: Morton Lippmann
Publisher: John Wiley & Sons
ISBN: 0470442883
Category : Science
Languages : en
Pages : 1189

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Book Description
Provides the most current information and research available for performing risk assessments on exposed individuals and populations, giving guidance to public health authorities, primary care physicians, and industrial managers Reviews current knowledge on human exposure to selected chemical agents and physical factors in the ambient environment Updates and revises the previous edition, in light of current scientific literature and its significance to public health concerns Includes new chapters on: airline cabin exposures, arsenic, endocrine disruptors, and nanoparticles

Health Effects of Man-made Minerals, Asbestos, and Hazardous Chemicals

Health Effects of Man-made Minerals, Asbestos, and Hazardous Chemicals PDF Author: Nachman Brautbar
Publisher: Princeton Scientific Publishing
ISBN:
Category : Asbestos
Languages : en
Pages : 270

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Book Description


Biopersistence of Respirable Synthetic Fibers and Minerals

Biopersistence of Respirable Synthetic Fibers and Minerals PDF Author:
Publisher:
ISBN:
Category : Air
Languages : en
Pages : 314

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Environmental Health Perspectives

Environmental Health Perspectives PDF Author:
Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 1162

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Mechanisms in Fibre Carcinogenesis

Mechanisms in Fibre Carcinogenesis PDF Author: Robert C. Brown
Publisher: Springer Science & Business Media
ISBN: 1468413635
Category : Medical
Languages : en
Pages : 564

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Book Description
The Editors are sorry that the production of this volume was delayed by the ill health of one of them and we hope that this does not detract from the value of the con tents. For once this delay is not the fault of any of the authors only the editors are to blame. Many of the workers in the field of fibre toxicology became convinced by the middle 1980's that the worst of the furore over asbestos was over although we were left with an intriguing problem - how does asbestos cause disease? It was expected that the future impact of fibres on human health would be very small since asbestos exposure would be controlled and there was little chance that man-made fibres would prove haz ardous. These man-made fibres are much thicker than asbestos and, in most cases, they are less durable in the body. Both of these properties are believed to make them much less likely to cause disease. However many of us had fallen into the habit of calling these materials "asbestos substitutes" and thus they have acquired a little of the notoriety at tached to the natural fibrous minerals. Very few of these man-made fibres are actually used as replacements for asbestos. Asbestos was not suitable for the uses to which the insulation wools are usually put and the ceramic fibres are replacements for fire brick not asbestos which is destroyed at the temperatures at which these materials are used.

Reviews in Environmental Health, 1994

Reviews in Environmental Health, 1994 PDF Author:
Publisher:
ISBN:
Category : Developmental neurophysiology
Languages : en
Pages : 182

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Book Description