Responsible Research with Biological Select Agents and Toxins

Responsible Research with Biological Select Agents and Toxins PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309150299
Category : Political Science
Languages : en
Pages : 189

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Book Description
The effort to understand and combat infectious diseases has, during the centuries, produced many key advances in science and medicine-including the development of vaccines, drugs, and other treatments. A subset of this research is conducted with agents that, like anthrax, not only pose a severe threat to the health of humans, plants, and animals but can also be used for ill-intended purposes. Such agents have been listed by the government as biological select agents and toxins. The 2001 anthrax letter attacks prompted the creation of new regulations aimed at increasing security for research with dangerous pathogens. The outcome of the anthrax letter investigation has raised concern about whether these measures are adequate. Responsible Research with Biological Select Agents and Toxins evaluates both the physical security of select agent laboratories and personnel reliability measures designed to ensure the trustworthiness of those with access to biological select agents and toxins. The book offers a set of guiding principles and recommended changes to minimize security risk and facilitate the productivity of research. The book recommends fostering a culture of trust and responsibility in the laboratory, engaging the community in oversight of the Select Agent Program, and enhancing the operation of the Select Agent Program.

Responsible Research with Biological Select Agents and Toxins

Responsible Research with Biological Select Agents and Toxins PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309150299
Category : Political Science
Languages : en
Pages : 189

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Book Description
The effort to understand and combat infectious diseases has, during the centuries, produced many key advances in science and medicine-including the development of vaccines, drugs, and other treatments. A subset of this research is conducted with agents that, like anthrax, not only pose a severe threat to the health of humans, plants, and animals but can also be used for ill-intended purposes. Such agents have been listed by the government as biological select agents and toxins. The 2001 anthrax letter attacks prompted the creation of new regulations aimed at increasing security for research with dangerous pathogens. The outcome of the anthrax letter investigation has raised concern about whether these measures are adequate. Responsible Research with Biological Select Agents and Toxins evaluates both the physical security of select agent laboratories and personnel reliability measures designed to ensure the trustworthiness of those with access to biological select agents and toxins. The book offers a set of guiding principles and recommended changes to minimize security risk and facilitate the productivity of research. The book recommends fostering a culture of trust and responsibility in the laboratory, engaging the community in oversight of the Select Agent Program, and enhancing the operation of the Select Agent Program.

Chemical and Biological Terrorism

Chemical and Biological Terrorism PDF Author: Committee on R&D Needs for Improving Civilian Medical Response to Chemical and Biological Terrorism Incidents
Publisher: National Academies Press
ISBN: 0309523141
Category : History
Languages : en
Pages : 303

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Book Description
The threat of domestic terrorism today looms larger than ever. Bombings at the World Trade Center and Oklahoma City's Federal Building, as well as nerve gas attacks in Japan, have made it tragically obvious that American civilians must be ready for terrorist attacks. What do we need to know to help emergency and medical personnel prepare for these attacks? Chemical and Biological Terrorism identifies the R&D efforts needed to implement recommendations in key areas: pre-incident intelligence, detection and identification of chemical and biological agents, protective clothing and equipment, early recognition that a population has been covertly exposed to a pathogen, mass casualty decontamination and triage, use of vaccines and pharmaceuticals, and the psychological effects of terror. Specific objectives for computer software development are also identified. The book addresses the differences between a biological and chemical attack, the distinct challenges to the military and civilian medical communities, and other broader issues. This book will be of critical interest to anyone involved in civilian preparedness for terrorist attack: planners, administrators, responders, medical professionals, public health and emergency personnel, and technology designers and engineers.

Biological Agents

Biological Agents PDF Author: Shiv Kant Prasad
Publisher: Discovery Publishing House
ISBN: 9788183563819
Category : Biological agents
Languages : en
Pages : 294

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Book Description


Handbook on Biological Warfare Preparedness

Handbook on Biological Warfare Preparedness PDF Author: S.J.S. Flora
Publisher: Academic Press
ISBN: 012812055X
Category : Medical
Languages : en
Pages : 306

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Book Description
Handbook on Biological Warfare Preparedness provides detailed information on biological warfare agents and their mode of transmission and spread. In addition, it explains methods of detection and medical countermeasures, including vaccine and post-exposure therapeutics, with specific sections detailing diseases, their transmission, clinical signs and symptoms, diagnosis, treatment, vaccines, prevention and management. This book is useful reading for researchers and advanced students in toxicology, but it will also prove helpful for medical students, civil administration, medical doctors, first responders and security forces. As the highly unpredictable nature of any event involving biological warfare agents has given rise to the need for the rapid development of accurate detection systems, this book is a timely resource on the topic. Introduces different bacterial and viral agents, including Ebola and other emerging threats and toxins Discusses medical countermeasures, including vaccines and post-exposure therapeutics Includes a comprehensive review of current methods of detection

A Review of Human Carcinogens

A Review of Human Carcinogens PDF Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Conference
Publisher:
ISBN:
Category : Carcinogens
Languages : en
Pages :

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Book Description


Strategies to Protect the Health of Deployed U.S. Forces

Strategies to Protect the Health of Deployed U.S. Forces PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309068754
Category : Medical
Languages : en
Pages : 273

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Book Description
Since Operation Desert Shield/Desert Storm, Gulf War veterans have expressed concerns about health effects that could be associated with their deployment and service during the war. Although similar concerns were raised after other military operations, the Gulf War deployment focused national attention on the potential, but uncertain, relationship between the presence of chemical and biological (CB) agents and other harmful agents in theater and health symptoms reported by military personnel. Strategies to Protect the Health of Deployed U.S. Forces which is one of the four two-year studies, examines the detection and tracking of exposures of deployed personnel to multiple harmful agents.

Bioterrorism and Biocrimes

Bioterrorism and Biocrimes PDF Author: W. Seth Carus
Publisher: The Minerva Group, Inc.
ISBN: 9781410100238
Category : History
Languages : en
Pages : 224

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Book Description
The working paper is divided into two main parts. The first part is a descriptive analysis of the illicit use of biological agents by criminals and terrorists. It draws on a series of case studies documented in the second part. The case studies describe every instance identifiable in open source materials in which a perpetrator used, acquired, or threatened to use a biological agent. While the inventory of cases is clearly incomplete, it provides an empirical basis for addressing a number of important questions relating to both biocrimes and bioterrorism. This material should enable policymakers concerned with bioterrorism to make more informed decisions. In the course of this project, the author has researched over 270 alleged cases involving biological agents. This includes all incidents found in open sources that allegedly occurred during the 20th Century. While the list is certainly not complete, it provides the most comprehensive existing unclassified coverage of instances of illicit use of biological agents.

Biodefense in the Age of Synthetic Biology

Biodefense in the Age of Synthetic Biology PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309465184
Category : Technology & Engineering
Languages : en
Pages : 189

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Book Description
Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.

The Soviet Biological Weapons Program

The Soviet Biological Weapons Program PDF Author: Milton Leitenberg
Publisher: Harvard University Press
ISBN: 0674065263
Category : History
Languages : en
Pages : 956

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Book Description
This is the first attempt to understand the full scope of the USSR’s offensive biological weapons research, from inception in the 1920s. Gorbachev tried to end the program, but the U.S. and U.K. never obtained clear evidence that he succeeded, raising the question whether the means for waging biological warfare could be present in Russia today.

Chemical and Biological Warfare

Chemical and Biological Warfare PDF Author: Eric Croddy
Publisher: Springer Science & Business Media
ISBN: 1461300258
Category : Science
Languages : en
Pages : 316

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Book Description
The armaments of chemical and biological warfare (CBW) are now widely held not just by nation-states, but by terrorist and criminal enterprises. The weapons themselves are relatively inexpensive and very easy to hide, allowing organizations of just a few dozen people to deploy potentially devastating attacks. While in the twentieth century most arms-control efforts focused, rightly, on nuclear arsenals, in the twenty-first century CBW will almost certainly require just as much attention. This book defines the basics of CBW for the concerned citizen, including non-alarmist scientific descriptions of the weapons and their antidotes, methods of deployment and defensive response, and the likelihood in the current global political climate of additional proliferation.