Author: Stephen J. Lippard
Publisher: John Wiley & Sons
ISBN: 0470166967
Category : Science
Languages : en
Pages : 559
Book Description
This comprehensive series of volumes on inorganic chemistry provides inorganic chemists with a forum for critical, authoritative evaluations of advances in every area of the discipline. Every volume reports recent progress with a significant, up-to-date selection of papers by internationally recognized researchers, complemented by detailed discussions and complete documentation. Each volume features a complete subject index and the series includes a cumulative index as well.
Bioinorganic Chemistry, Volume 38
Author: Stephen J. Lippard
Publisher: John Wiley & Sons
ISBN: 0470166967
Category : Science
Languages : en
Pages : 559
Book Description
This comprehensive series of volumes on inorganic chemistry provides inorganic chemists with a forum for critical, authoritative evaluations of advances in every area of the discipline. Every volume reports recent progress with a significant, up-to-date selection of papers by internationally recognized researchers, complemented by detailed discussions and complete documentation. Each volume features a complete subject index and the series includes a cumulative index as well.
Publisher: John Wiley & Sons
ISBN: 0470166967
Category : Science
Languages : en
Pages : 559
Book Description
This comprehensive series of volumes on inorganic chemistry provides inorganic chemists with a forum for critical, authoritative evaluations of advances in every area of the discipline. Every volume reports recent progress with a significant, up-to-date selection of papers by internationally recognized researchers, complemented by detailed discussions and complete documentation. Each volume features a complete subject index and the series includes a cumulative index as well.
Research Frontiers in Magnetochemistry
Author: Charles J. O'Connor
Publisher: World Scientific
ISBN: 9789810212469
Category : Science
Languages : en
Pages : 428
Book Description
Over the past 25 years, there have been many advances in the understanding of magnetic phenomena in molecular systems. For example, a variety of low-dimensional materials, and many new ferromagnetic, antiferromagnetic, and ferrimagnetic systems have been synthesized and analyzed; metal cluster compounds that exhibit magnetic exchange have been examined; new orbital overlap theories have been proposed to explain magneto-structural correlations in exchange coupled systems; and efforts directed toward the preparation of an organic ferromagnetic material have produced new and interesting compounds. There have also been many advances in the use of magnetism as a probe of inorganic biomolecules.This volume brings together reviews of current research in magnetochemistry that are written by the world's leading researchers in the fields of chemistry, physics, materials science, and magnetism. It contains comprehensive and in-depth reviews that describe some of the current activities of these scientists and their research and lays the foundation for future research endeavors.
Publisher: World Scientific
ISBN: 9789810212469
Category : Science
Languages : en
Pages : 428
Book Description
Over the past 25 years, there have been many advances in the understanding of magnetic phenomena in molecular systems. For example, a variety of low-dimensional materials, and many new ferromagnetic, antiferromagnetic, and ferrimagnetic systems have been synthesized and analyzed; metal cluster compounds that exhibit magnetic exchange have been examined; new orbital overlap theories have been proposed to explain magneto-structural correlations in exchange coupled systems; and efforts directed toward the preparation of an organic ferromagnetic material have produced new and interesting compounds. There have also been many advances in the use of magnetism as a probe of inorganic biomolecules.This volume brings together reviews of current research in magnetochemistry that are written by the world's leading researchers in the fields of chemistry, physics, materials science, and magnetism. It contains comprehensive and in-depth reviews that describe some of the current activities of these scientists and their research and lays the foundation for future research endeavors.
Metal Compounds in Cancer Therapy
Author: S.P. Fricker
Publisher: Springer Science & Business Media
ISBN: 9401112525
Category : Medical
Languages : en
Pages : 269
Book Description
The discovery of the antitumour activity of cisplatin in 1965 and its subsequent introduction into clinical trials in 1971 was the catalyst for a major international research effort investigating the potential of metal compounds in cancer therapy. Cisplatin now occupies an important place in the armamentarium of the oncologist due to its effectiveness in the treatment of testicular cancer. A second generation analogue, carbo platin, offers reduced toxicity together with therapeutic activity, which gives it a place in the front-line therapy of genitourinary cancers. These and other successes have encouraged the search for novel metal-based drugs for cancer therapy. Research has shown that metal compounds have potential for activity not only as cytotoxic antitumour agents, but also in areas such as adjuvant therapy, diagnosis and immunotherapy. The aim of this book is to review and describe the major achievements and developments arising from this international research effort. The contributing authors come from labora tories throughout Europe and America and represent the many disci plines characteristic of this research, such as clinical research, pharmacology, tumour biology and inorganic medicinal chemistry.
Publisher: Springer Science & Business Media
ISBN: 9401112525
Category : Medical
Languages : en
Pages : 269
Book Description
The discovery of the antitumour activity of cisplatin in 1965 and its subsequent introduction into clinical trials in 1971 was the catalyst for a major international research effort investigating the potential of metal compounds in cancer therapy. Cisplatin now occupies an important place in the armamentarium of the oncologist due to its effectiveness in the treatment of testicular cancer. A second generation analogue, carbo platin, offers reduced toxicity together with therapeutic activity, which gives it a place in the front-line therapy of genitourinary cancers. These and other successes have encouraged the search for novel metal-based drugs for cancer therapy. Research has shown that metal compounds have potential for activity not only as cytotoxic antitumour agents, but also in areas such as adjuvant therapy, diagnosis and immunotherapy. The aim of this book is to review and describe the major achievements and developments arising from this international research effort. The contributing authors come from labora tories throughout Europe and America and represent the many disci plines characteristic of this research, such as clinical research, pharmacology, tumour biology and inorganic medicinal chemistry.
Inorganic Chemistry
Author: William W. Porterfield
Publisher: Academic Press
ISBN: 0323138942
Category : Science
Languages : en
Pages : 938
Book Description
This is one of the few books available that uses unifying theoretical concepts to present inorganic chemistry at the advanced undergraduate and graduate levels--most texts are organized around the periodic table, while this one is structured after bonding models, structure types, and reaction patterns. But the real strength of Porterfield's Second Edition is its clear presentation of ample background description, especially in recent areas of development such as cluster molecules, industrial catalysis, and bio-inorganic chemistry. This information will enable students to understand most current journals, empowering them to stay abreast of the latest advances in the field. Specific improvements of the Second Edition include new chapters on materials-science applications and bioinorganic chemistry, an extended discussion of transition-metal applications (including cuprate superconductors), and extended Tanabe-Sugano diagrams. - Extended treatment of inorganic materials science--ceramics, refractories, magnetic materials, superconductors--in the context of solid-state chemistry - Extended coverage of biological systems and their chemical and physiological consequences--02 metabolism, N2 fixation, muscle action, iron storage, cisplatin and nucleic acid structural probes, and photosynthesis - Unusual structures and species--silatranes, metallacarboranes, alkalides and electrides, vapor-deposition species, proton and hybrid sponges, massive transition-metal clusters, and agostic ligands - Thorough examination of industrial processes using organometallic catalysts and their mechanisms - Entropy-driven reactions - Complete discussion of inorganic photochemistry
Publisher: Academic Press
ISBN: 0323138942
Category : Science
Languages : en
Pages : 938
Book Description
This is one of the few books available that uses unifying theoretical concepts to present inorganic chemistry at the advanced undergraduate and graduate levels--most texts are organized around the periodic table, while this one is structured after bonding models, structure types, and reaction patterns. But the real strength of Porterfield's Second Edition is its clear presentation of ample background description, especially in recent areas of development such as cluster molecules, industrial catalysis, and bio-inorganic chemistry. This information will enable students to understand most current journals, empowering them to stay abreast of the latest advances in the field. Specific improvements of the Second Edition include new chapters on materials-science applications and bioinorganic chemistry, an extended discussion of transition-metal applications (including cuprate superconductors), and extended Tanabe-Sugano diagrams. - Extended treatment of inorganic materials science--ceramics, refractories, magnetic materials, superconductors--in the context of solid-state chemistry - Extended coverage of biological systems and their chemical and physiological consequences--02 metabolism, N2 fixation, muscle action, iron storage, cisplatin and nucleic acid structural probes, and photosynthesis - Unusual structures and species--silatranes, metallacarboranes, alkalides and electrides, vapor-deposition species, proton and hybrid sponges, massive transition-metal clusters, and agostic ligands - Thorough examination of industrial processes using organometallic catalysts and their mechanisms - Entropy-driven reactions - Complete discussion of inorganic photochemistry
Metal Ions in Biological Systems
Author: Astrid Sigel
Publisher: CRC Press
ISBN: 9780824702892
Category : Science
Languages : en
Pages : 756
Book Description
"Focuses on the vibrant area of probing enzymes or proteins by metal ions and small complexes. Offers a summary of the basic characteristics of the amide bond, emphasizing its proton and metal ion interactions, including a quantitative analysis of its hydrolysis and formation."
Publisher: CRC Press
ISBN: 9780824702892
Category : Science
Languages : en
Pages : 756
Book Description
"Focuses on the vibrant area of probing enzymes or proteins by metal ions and small complexes. Offers a summary of the basic characteristics of the amide bond, emphasizing its proton and metal ion interactions, including a quantitative analysis of its hydrolysis and formation."
Characterization, Properties and Applications
Author: Tracey Rouault
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110480433
Category : Science
Languages : en
Pages : 466
Book Description
This volume on iron-sulfur proteins includes chapters that describe the initial discovery of iron-sulfur proteins in the 1960s to elucidation of the roles of iron sulfur clusters as prosthetic groups of enzymes, such as the citric acid cycle enzyme, aconitase, and numerous other proteins, ranging from nitrogenase to DNA repair proteins. The capacity of iron sulfur clusters to accept and delocalize single electrons is explained by basic chemical principles, which illustrate why iron sulfur proteins are uniquely suitable for electron transport and other activities. Techniques used for detection and stabilization of iron-sulfur clusters, including EPR and Mossbauer spectroscopies, are discussed because they are important for characterizing unrecognized and elusive iron sulfur proteins. Recent insights into how nitrogenase works have arisen from multiple advances, described here, including studies of high-resolution crystal structures.
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110480433
Category : Science
Languages : en
Pages : 466
Book Description
This volume on iron-sulfur proteins includes chapters that describe the initial discovery of iron-sulfur proteins in the 1960s to elucidation of the roles of iron sulfur clusters as prosthetic groups of enzymes, such as the citric acid cycle enzyme, aconitase, and numerous other proteins, ranging from nitrogenase to DNA repair proteins. The capacity of iron sulfur clusters to accept and delocalize single electrons is explained by basic chemical principles, which illustrate why iron sulfur proteins are uniquely suitable for electron transport and other activities. Techniques used for detection and stabilization of iron-sulfur clusters, including EPR and Mossbauer spectroscopies, are discussed because they are important for characterizing unrecognized and elusive iron sulfur proteins. Recent insights into how nitrogenase works have arisen from multiple advances, described here, including studies of high-resolution crystal structures.
Environmental Impacts of Soil Component Interactions
Author: P. M. Huang
Publisher: CRC Press
ISBN: 9780873719148
Category : Technology & Engineering
Languages : en
Pages : 472
Book Description
This book addresses the interactions of soil minerals with organics and microbes and their impacts on the dynamics, transformations, and toxicity of metals, metalloids, other inorganics, and xenobiotics that affect land quality and ecosystem health. It is the result of the work group on "interactions of soil minerals with organic components and microorganisms" in the International Society of Soil Science.
Publisher: CRC Press
ISBN: 9780873719148
Category : Technology & Engineering
Languages : en
Pages : 472
Book Description
This book addresses the interactions of soil minerals with organics and microbes and their impacts on the dynamics, transformations, and toxicity of metals, metalloids, other inorganics, and xenobiotics that affect land quality and ecosystem health. It is the result of the work group on "interactions of soil minerals with organic components and microorganisms" in the International Society of Soil Science.
Current Trends in X-Ray Crystallography
Author: Annamalai Chandrasekaran
Publisher: BoD – Books on Demand
ISBN: 9533077549
Category : Science
Languages : en
Pages : 452
Book Description
This book on X-ray Crystallography is a compilation of current trends in the use of X-ray crystallography and related structural determination methods in various fields. The methods covered here include single crystal small-molecule X-ray crystallography, macromolecular (protein) single crystal X-ray crystallography, and scattering and spectroscopic complimentary methods. The fields range from simple organic compounds, metal complexes to proteins, and also cover the meta-analyses of the database for weak interactions.
Publisher: BoD – Books on Demand
ISBN: 9533077549
Category : Science
Languages : en
Pages : 452
Book Description
This book on X-ray Crystallography is a compilation of current trends in the use of X-ray crystallography and related structural determination methods in various fields. The methods covered here include single crystal small-molecule X-ray crystallography, macromolecular (protein) single crystal X-ray crystallography, and scattering and spectroscopic complimentary methods. The fields range from simple organic compounds, metal complexes to proteins, and also cover the meta-analyses of the database for weak interactions.
Reviews of Environmental Contamination and Toxicology
Author: George W. Ware
Publisher: Springer Science & Business Media
ISBN: 1461216842
Category : Science
Languages : en
Pages : 160
Book Description
Reviews of Environmental Contamination and Toxicology provides detailed review articles concerned with aspects of chemical contaminants, including pesticides, in the total environment with toxicological considerations and consequences. C.E. CASTRO: Environmental Dehalogenation-Chemistry and Mechanism M.J. KENNISH: Trace Metal-Sediment Dynamics in Estuaries: Pollution Assessment R.D. VINEBROOKE AND R. CULLIMORE: Natural Organic Matter and the Bound Water Concept in Aquatic Ecosystems
Publisher: Springer Science & Business Media
ISBN: 1461216842
Category : Science
Languages : en
Pages : 160
Book Description
Reviews of Environmental Contamination and Toxicology provides detailed review articles concerned with aspects of chemical contaminants, including pesticides, in the total environment with toxicological considerations and consequences. C.E. CASTRO: Environmental Dehalogenation-Chemistry and Mechanism M.J. KENNISH: Trace Metal-Sediment Dynamics in Estuaries: Pollution Assessment R.D. VINEBROOKE AND R. CULLIMORE: Natural Organic Matter and the Bound Water Concept in Aquatic Ecosystems
Artificial Nucleases
Author: Marina A. Zenkova
Publisher: Springer Science & Business Media
ISBN: 364218510X
Category : Science
Languages : en
Pages : 304
Book Description
The development of agents capable of cleaving RNA and DNA has attracted considerable attention from researchers in the last few years, because of the immediate and very important applications they can find in the emerging fields of biotechnology and pharmacology. There are essentially two classes of these agents - nucleases that occur naturally inside cells and synthetically produced artificial nucleases. The first class includes protein enzyme nucle ases and catalytic RNA structured ribozymes that perform cleavage of the phosphodiester bonds in nucleic acids according to a hydrolytic pathway in the course of different biochemical processes in the cell. A different pathway is used by some antibiotics which cleave DNA via redox-based mechanisms resulting in oxidative damage of nucleotide units and breakage of the DNA backbone. The above molecules are indispensable tools for manipulating nucleic acids and processing RNA; DNA-cleaving antibiotics and cytotoxic ribonucleases have demonstrated utility as chemotherapeutic agents. The second class, artificial nucleases, are rationally designed to imitate the active centers of natural enzymes by simple structures possessing minimal sets of the most important characteristics that are essential for catalysis. A dif ferent approach, in vitro selection, was also used to create artificial RNA and DNA enzymes capable of cleaving RNA. Being less efficient and specific as compared to the natural enzymes, the primitive mimics are smaller and robust and can function in a broad range of conditions.
Publisher: Springer Science & Business Media
ISBN: 364218510X
Category : Science
Languages : en
Pages : 304
Book Description
The development of agents capable of cleaving RNA and DNA has attracted considerable attention from researchers in the last few years, because of the immediate and very important applications they can find in the emerging fields of biotechnology and pharmacology. There are essentially two classes of these agents - nucleases that occur naturally inside cells and synthetically produced artificial nucleases. The first class includes protein enzyme nucle ases and catalytic RNA structured ribozymes that perform cleavage of the phosphodiester bonds in nucleic acids according to a hydrolytic pathway in the course of different biochemical processes in the cell. A different pathway is used by some antibiotics which cleave DNA via redox-based mechanisms resulting in oxidative damage of nucleotide units and breakage of the DNA backbone. The above molecules are indispensable tools for manipulating nucleic acids and processing RNA; DNA-cleaving antibiotics and cytotoxic ribonucleases have demonstrated utility as chemotherapeutic agents. The second class, artificial nucleases, are rationally designed to imitate the active centers of natural enzymes by simple structures possessing minimal sets of the most important characteristics that are essential for catalysis. A dif ferent approach, in vitro selection, was also used to create artificial RNA and DNA enzymes capable of cleaving RNA. Being less efficient and specific as compared to the natural enzymes, the primitive mimics are smaller and robust and can function in a broad range of conditions.