Quantitative Fundamentals of Molecular and Cellular Bioengineering PDF Download
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Author: K. Dane Wittrup
Publisher: MIT Press
ISBN: 0262042657
Category : Science
Languages : en
Pages : 593
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Book Description
A comprehensive presentation of essential topics for biological engineers, focusing on the development and application of dynamic models of biomolecular and cellular phenomena. This book describes the fundamental molecular and cellular events responsible for biological function, develops models to study biomolecular and cellular phenomena, and shows, with examples, how models are applied in the design and interpretation of experiments on biological systems. Integrating molecular cell biology with quantitative engineering analysis and design, it is the first textbook to offer a comprehensive presentation of these essential topics for chemical and biological engineering. The book systematically develops the concepts necessary to understand and study complex biological phenomena, moving from the simplest elements at the smallest scale and progressively adding complexity at the cellular organizational level, focusing on experimental testing of mechanistic hypotheses. After introducing the motivations for formulation of mathematical rate process models in biology, the text goes on to cover such topics as noncovalent binding interactions; quantitative descriptions of the transient, steady state, and equilibrium interactions of proteins and their ligands; enzyme kinetics; gene expression and protein trafficking; network dynamics; quantitative descriptions of growth dynamics; coupled transport and reaction; and discrete stochastic processes. The textbook is intended for advanced undergraduate and graduate courses in chemical engineering and bioengineering, and has been developed by the authors for classes they teach at MIT and the University of Minnesota.
Author: K. Dane Wittrup
Publisher: MIT Press
ISBN: 0262042657
Category : Science
Languages : en
Pages : 593
Get Book Here
Book Description
A comprehensive presentation of essential topics for biological engineers, focusing on the development and application of dynamic models of biomolecular and cellular phenomena. This book describes the fundamental molecular and cellular events responsible for biological function, develops models to study biomolecular and cellular phenomena, and shows, with examples, how models are applied in the design and interpretation of experiments on biological systems. Integrating molecular cell biology with quantitative engineering analysis and design, it is the first textbook to offer a comprehensive presentation of these essential topics for chemical and biological engineering. The book systematically develops the concepts necessary to understand and study complex biological phenomena, moving from the simplest elements at the smallest scale and progressively adding complexity at the cellular organizational level, focusing on experimental testing of mechanistic hypotheses. After introducing the motivations for formulation of mathematical rate process models in biology, the text goes on to cover such topics as noncovalent binding interactions; quantitative descriptions of the transient, steady state, and equilibrium interactions of proteins and their ligands; enzyme kinetics; gene expression and protein trafficking; network dynamics; quantitative descriptions of growth dynamics; coupled transport and reaction; and discrete stochastic processes. The textbook is intended for advanced undergraduate and graduate courses in chemical engineering and bioengineering, and has been developed by the authors for classes they teach at MIT and the University of Minnesota.
Author: Guruprasad Madhavan
Publisher: Springer Science & Business Media
ISBN: 038776495X
Category : Technology & Engineering
Languages : en
Pages : 524
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Book Description
This indispensable guide provides a roadmap to the broad and varied career development opportunities in bioengineering, biotechnology, and related fields. Eminent practitioners lay out career paths related to academia, industry, government and regulatory affairs, healthcare, law, marketing, entrepreneurship, and more. Lifetimes of experience and wisdom are shared, including "war stories," strategies for success, and discussions of the authors’ personal views and motivations.
Author: John Villadsen
Publisher: John Wiley & Sons
ISBN: 3527697462
Category : Science
Languages : en
Pages : 574
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Book Description
A thorough introduction to the basics of bioengineering, with a focus on applications in the emerging "white" biotechnology industry. As such, this latest volume in the "Advanced Biotechnology" series covers the principles for the design and analysis of industrial bioprocesses as well as the design of bioremediation systems, and several biomedical applications. No fewer than seven chapters introduce stoichiometry, kinetics, thermodynamics and the design of ideal and real bioreactors, illustrated by more than 50 practical examples. Further chapters deal with the tools that enable an understanding of the behavior of cell cultures and enzymatically catalyzed reactions, while others discuss the analysis of cultures at the level of the cell, as well as structural frameworks for the successful scale-up of bioreactions. In addition, a short survey of downstream processing options and the control of bioreactions is given. With contributions from leading experts in industry and academia, this is a comprehensive source of information peer-reviewed by experts in the field.
Author: Yuan-cheng Fung
Publisher: World Scientific
ISBN: 9789810243982
Category : Technology & Engineering
Languages : en
Pages : 318
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Book Description
Bioengineering is attracting many high quality students. This invaluable book has been written for beginning students of bioengineering, and is aimed at instilling a sense of engineering in them.Engineering is invention and designing things that do not exist in nature for the benefit of humanity. Invention can be taught by making inventive thinking a conscious part of our daily life. This is the approach taken by the authors of this book. Each author discusses an ongoing project, and gives a sample of a professional publication. Students are asked to work through a sequence of assignments and write a report. Almost everybody soon realizes that more scientific knowledge is needed, and a strong motivation for the study of science is generated. The teaching of inventive thinking is a new trend in engineering education. Bioengineering is a good field with which to begin this revolution in engineering education, because it is a youthful, developing interdisciplinary field.
Author: Mirjana Pavlovic
Publisher: Springer
ISBN: 3319107984
Category : Technology & Engineering
Languages : en
Pages : 315
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Book Description
This book explores critical principles and new concepts in bioengineering, integrating the biological, physical and chemical laws and principles that provide a foundation for the field. Both biological and engineering perspectives are included, with key topics such as the physical-chemical properties of cells, tissues and organs; principles of molecules; composition and interplay in physiological scenarios; and the complex physiological functions of heart, neuronal cells, muscle cells and tissues. Chapters evaluate the emerging fields of nanotechnology, drug delivery concepts, biomaterials, and regenerative therapy. The leading individuals and events are introduced along with their critical research. Bioengineering: A Conceptual Approach is a valuable resource for professionals or researchers interested in understanding the central elements of bioengineering. Advanced-level students in biomedical engineering and computer science will also find this book valuable as a secondary textbook or reference.
Author: Christian Larroche
Publisher: Elsevier
ISBN: 0444636749
Category : Science
Languages : en
Pages : 852
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Book Description
Current Developments in Biotechnology and Bioengineering: Bioprocesses, Bioreactors and Controls provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, reviewing industrial biotechnology and bioengineering practices that facilitate and enhance the transition of processes from lab to plant scale, which is becoming increasingly important as such transitions continue to grow in frequency. Focusing on industrial bioprocesses, bioreactors for bioprocesses, and controls for bioprocesses, this title reviews industrial practice to identify bottlenecks and propose solutions, highlighting that the optimal control of a bioprocess involves not only maximization of product yield, but also taking into account parameters such as quality assurance and environmental aspects. - Describes industrial bioprocesses based on the reaction media - Lists the type of bioreactors used for a specific bioprocess/application - Outlines the principles of control systems in various bioprocesses
Author: Guigen Zhang
Publisher: CRC Press
ISBN: 1466517565
Category : Medical
Languages : en
Pages : 480
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Book Description
Arguably the first book of its kind, Computational Bioengineering explores the power of multidisciplinary computer modeling in bioengineering. Written by experts, the book examines the interplay of multiple governing principles underlying common biomedical devices and problems, bolstered by case studies. It shows you how to take advantage of the la
Author: Giuseppe Orlando
Publisher: Academic Press
ISBN: 0128148349
Category : Science
Languages : en
Pages : 892
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Book Description
Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 1, sets a new standard in transplant and regenerative medicine. The book details the-state-of-the-art in modern whole pancreas and islet transplantation, including donor selection, immunosuppression, complications, allograft pathology, and more. As regenerative medicine is changing the premise of solid organ transplantation, this volume catalogs the technologies being developed and the methods being implemented to bioengineer or regenerate the endocrine pancreas in order to more effectively treat diabetes. Edited and authored by unparalleled leaders in the field, this new volume argues for a much needed synergy between organ transplantation and regenerative medicine. - Provides comprehensive and cutting-edge knowledge of whole pancreas and islet transplantation - Includes sections that address donor selection, immunosuppression, complications, allograft pathology, and more - Offers an update on the progress of regenerative medicine research aimed at beta cells replacement in the treatment of diabetes
Author: S. A. Berger
Publisher: OUP Oxford
ISBN: 9780198565154
Category : Medical
Languages : en
Pages : 540
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Book Description
Bioengineering is the application of physical sciences and mathematics to the study of living organisms and structures. This book introduces the student to the physical processes and engineering aspects of a systems performance both under normal and abnormal conditions, and helps them to design, develop and use diagnostic or artificial devices to measure, improve, safeguard or replace life functions.
Author: Ho Nam Chang
Publisher: John Wiley & Sons
ISBN: 3527803300
Category : Science
Languages : en
Pages : 720
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Book Description
With more than 40 contributions from expert authors, this is an extensive overview of all important research topics in the field of bioengineering, including metabolic engineering, biotransformations and biomedical applications. Alongside several chapters dealing with biotransformations and biocatalysis, a whole section is devoted to biofuels and the utilization of biomass. Current perspectives on synthetic biology and metabolic engineering approaches are presented, involving such example organisms as Escherichia coli and Corynebacterium glutamicum, while a further section covers topics in biomedical engineering including drug delivery systems and biopharmaceuticals. The book concludes with chapters on computer-aided bioprocess engineering and systems biology. This is a part of the Advanced Biotechnology book series, covering all pertinent aspects of the field with each volume prepared by eminent scientists who are experts on the topic in question. Invaluable reading for biotechnologists and bioengineers, as well as those working in the chemical and pharmaceutical industries. Advanced Biotechnology Biotechnology is a broad, interdisciplinary field of science, combining biological sciences and relevant engineering disciplines, that is becoming increasingly important as it benefits the environment and society as a whole. Recent years have seen substantial advances in all areas of biotechnology, resulting in the emergence of brand new fields. To reflect this progress, Sang-Yup Lee (KAIST, South Korea), Jens Nielsen (Chalmers University, Sweden), and Gregory Stephanopoulos (MIT, USA) have joined forces as the editors of a new Wiley-VCH book series. Advanced Biotechnology will cover all pertinent aspects of the field and each volume will be prepared by eminent scientists who are experts on the topic in question.
