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Author: Valdur A. Saks
Publisher: Springer Science & Business Media
ISBN: 1461556538
Category : Science
Languages : en
Pages : 444
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Book Description
This volume continues the discussion of the problems of in vivo and in vitro. The recently solved X-ray structure of the mitochondrial creatine kinase and its molecular biology cellular bioenergetics - the tradition we started in 1994 by publication of the focused issue of Molecular and Cellular are analyzed with respect to its molecular physiology and Biochemistry, volume 133/134 and a book 'Cellular Bio functional coupling to the adenine nucleotide translocase, as energetics: role of coupled creatine kinases' edited by V. Saks well as its participation, together with the adenylate kinase and R. Ventura-Clapier and published by Kluwer Publishers, system, in intracellular energy transfer. The results of the Dordrecht -Boston. In the present volume, use of quantitative studies of creatine kinase deficient transgenic mice are methods of studies of organized metabolic systems, such as summarized and analyzed by using mathematical models of mathematical modeling and Metabolic Control Analysis, for the compartmentalized energy transfer, thus combining two investigation of the problems of bioenergetics of the cell is powerful new methods of the research. All these results, described together with presentation of new experimental together with the physiological and NMR data on the cardiac results. The following central problems of the cellular bio metabolic and mitochondrial responses to work-load changes energetics are the focus of the discussions: the mechanisms concord to the concept of metabolic networks of energy of regulation of oxidative phosphorylation in the cells in vivo transfer and feedback regulation.
Author: Valdur A. Saks
Publisher: Springer Science & Business Media
ISBN: 1461556538
Category : Science
Languages : en
Pages : 444
Get Book Here
Book Description
This volume continues the discussion of the problems of in vivo and in vitro. The recently solved X-ray structure of the mitochondrial creatine kinase and its molecular biology cellular bioenergetics - the tradition we started in 1994 by publication of the focused issue of Molecular and Cellular are analyzed with respect to its molecular physiology and Biochemistry, volume 133/134 and a book 'Cellular Bio functional coupling to the adenine nucleotide translocase, as energetics: role of coupled creatine kinases' edited by V. Saks well as its participation, together with the adenylate kinase and R. Ventura-Clapier and published by Kluwer Publishers, system, in intracellular energy transfer. The results of the Dordrecht -Boston. In the present volume, use of quantitative studies of creatine kinase deficient transgenic mice are methods of studies of organized metabolic systems, such as summarized and analyzed by using mathematical models of mathematical modeling and Metabolic Control Analysis, for the compartmentalized energy transfer, thus combining two investigation of the problems of bioenergetics of the cell is powerful new methods of the research. All these results, described together with presentation of new experimental together with the physiological and NMR data on the cardiac results. The following central problems of the cellular bio metabolic and mitochondrial responses to work-load changes energetics are the focus of the discussions: the mechanisms concord to the concept of metabolic networks of energy of regulation of oxidative phosphorylation in the cells in vivo transfer and feedback regulation.
Author: Carlos M. Palmeira
Publisher: Humana
ISBN: 9781071642634
Category : Science
Languages : en
Pages : 0
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Book Description
Author: David G. Nicholls
Publisher: Gulf Professional Publishing
ISBN: 9780125181211
Category : Nature
Languages : en
Pages : 334
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Book Description
Revised and updated to include the many developments that have taken place in bioenergetics, this text covers the structures of key membrane proteins involved in bioenergetics and mitochondrial physiology.
Author: Elissavet Kardami
Publisher: Springer Science & Business Media
ISBN: 9781402072963
Category : Medical
Languages : en
Pages : 222
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Book Description
Cardiac cell biology has come of age. Recognition of activated or modified signaling molecules by specific antibodies, new selective inhibitors, and fluorescent fusion tags are but a few of the tools used to dissect signaling pathways and cross-talk mechanisms that may eventually allow rational drug design. Understanding the regulation of cardiac hypertrophy in all its complexity remains a fundamental goal of cardiac research. Since the advancement of adenovirally mediated gene transfer, transfection efficiency is no longer a limiting factor in the study of cardiomyocytes. A limiting factor in considering cell transplantion as a strategy to repair the damaged heart is cell availability at the right time. Cardiac gap junctions, intercellular communication channels that allow electrical and metabolic coupling and play an important role in arrhythmogenesis are now understood to be exquisite sensors of cardiac change. The reports in this volume incLude elegant studies that made use of cutting edge technological advances and many specialized reagents to address these issues.
Author: Kersti Tepp
Publisher:
ISBN: 9789949231553
Category :
Languages : en
Pages : 218
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Book Description
Author: Sergio Papa
Publisher: Springer Science & Business Media
ISBN:
Category : Medical
Languages : en
Pages : 976
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Book Description
The book covers major advances made in cellular bioenergetics, a central topic in biological and medical research. The chapters, contributed by authors representing major groups working in the field, extend from the latest advancements in X-ray crystallographic analysis of the atomic structure of energy transfer membrane proteins and analysis of their mechanism of action, to perspectives on the implication of their genetic and phenotypic defects in human diseases. The book, intended for researchers, clinicians and students, aims at providing an up-to-date appraisal of this rapidly developing biomedical field. The book consists of thirty-one chapters contributed by leading experts in the field of cellular bioenergetics. Three sections cover the X-ray crystallographic analysis, mutational analysis and mechanism of action of mitochondrial and prokaryotic respiratory enzymes, ATP synthase and mitochondrial carriers. One section deals with genetics and biogenesis of mitochondria. The fourth section covers genetic and phenotypic defects in mitochondrial energy transfer proteins associated with inborn and/or degenerative human diseases and aging.
Author: Val Vallyathan
Publisher: Springer Science & Business Media
ISBN: 1461510872
Category : Science
Languages : en
Pages : 393
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Book Description
A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases including Alzheimer's disease, atherosclerosis, diabetes, arthritis, and Parkinson's disease, as well as disorders of the eye, skin, cardiac, and pulmonary systems are discussed in this volume, along with scientific evidence supporting the value of dietary supplementation with antioxidants in the prevention of cellular damage leading to chronic disease. Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.
Author: Vladimir V. Ghukasyan
Publisher: CRC Press
ISBN: 1466509996
Category : Medical
Languages : en
Pages : 404
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Book Description
From the Lab to Clinical Settings-Advances in Quantitative, Noninvasive Optical DiagnosticsNoninvasive fluorescence imaging techniques, novel fluorescent labels, and natural biomarkers are revolutionizing our knowledge of cellular processes, signaling and metabolic pathways, the underlying mechanisms for health problems, and the identification of n
Author: Christian Vial
Publisher: Nova Publishers
ISBN: 9781594547157
Category : Medical
Languages : en
Pages : 296
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Book Description
Creatine kinases and arginine kinases are an historical model in enzymology. They belong to the large family of phosphagen kinases which transfer a phosphoryl group from ATP to a nitrogen atom within a guanidinium group to form that was called by the early muscle physiologists a 'phosphagen'. These compounds and the enzymes that catalyse their formation and use are present in cells with important and rapidly fluctuating energy requirements.
Author: Téa Kekelidze
Publisher: IOS Press
ISBN: 9781586032333
Category :
Languages : en
Pages : 204
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Book Description
