Medical Enzymology

Medical Enzymology PDF Author: Tarek H. El-Metwally
Publisher:
ISBN: 9781608769049
Category : Biocatalysis
Languages : en
Pages : 0

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Book Description
Understanding enzyme kinetics and structure-function relationship enables us to explain the metabolic regulation and integration. The information also helps us understanding action of specific toxins, drug metabolism and disease pathogenesis. This enables us to invent suitable interventions to circumvent unfavourable and invest the favourable effects on enzymes and to design more efficient biocatalysts for therapeutic and industrial uses. This book presents all of the fundamental knowledge of enzymology in a very simple way.

Medical Enzymology

Medical Enzymology PDF Author: Tarek H. El-Metwally
Publisher:
ISBN: 9781608769049
Category : Biocatalysis
Languages : en
Pages : 0

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Book Description
Understanding enzyme kinetics and structure-function relationship enables us to explain the metabolic regulation and integration. The information also helps us understanding action of specific toxins, drug metabolism and disease pathogenesis. This enables us to invent suitable interventions to circumvent unfavourable and invest the favourable effects on enzymes and to design more efficient biocatalysts for therapeutic and industrial uses. This book presents all of the fundamental knowledge of enzymology in a very simple way.

Bioactive Heterocycles

Bioactive Heterocycles PDF Author: K. L. Ameta
Publisher: Nova Science Publishers
ISBN: 9781622576364
Category : Bioactive compounds
Languages : en
Pages : 0

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Book Description
This book is a critical and lucid account of various synthetic methodologies and biological activities of different sized bioactive heterocyclic compounds. In effect, this book imparts a great deal of comprehensive reviews about the chemistry and biology of selected groups of heterocycles and natural products including important pharmaceuticals as well as agrochemical pesticides in one handy project. Besides, this compendious effort encompasses different methods of synthesis and biological evaluation of heterocyclic compounds. The main purpose of this book is to share the recent advances and scope of Bioactive Heterocycles for the future avenues in the field. It has specifically been designed by keeping in mind the wide interests of individuals engaged in the design and synthesis of biologically active heterocyclic compounds as well as research scientists in academia and industry. The authors expect this book to be a standard reference in Universities and industrial libraries.

Bioluminescence

Bioluminescence PDF Author: David J. Rodgerson
Publisher:
ISBN: 9781612097473
Category : Bioluminescence
Languages : en
Pages : 0

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Book Description
This book presents current research data in the study of the characteristics, adaptations and biotechnology of bioluminescence. Topics discussed include ATP-Driven bioluminescence; the coupling of luciferases to nanomaterials; the characteristics and adaptations of bioluminescent bacterial biosensors for acyl-HSL signal detection, quantification and tentative identification of acyl-HSLs; using bacterial biosensors to determine the toxicity of nanomaterials and other xenobiotics; and, the visual spectral mechanisms and bioluminescent optical signaling in beetles.

Oligosaccharides

Oligosaccharides PDF Author: Nicole S. Gordon
Publisher:
ISBN: 9781611221930
Category : Carbohydrates
Languages : en
Pages : 0

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Book Description
An oligosaccharide is a saccharide polymer containing a small number of component sugars, also known as simple sugars (monosaccharides). Oligosaccharides can have many functions; for example, they are commonly found on the plasma membrane of animal cells where they can play a role in cell-cell recognition. This book presents topical research data in the study of oligosaccharides, including the study of human and bovine milk oligosaccharides; the health benefits and commercial applications of prebiotic oligosaccharides; classification of oligosaccharides synthesised by enzymes; oligosaccharides from sucrose via glycansucrases; and the Mannan oligosaccharides in aquaculture.

Butyrate

Butyrate PDF Author: Cong-Jun Li
Publisher: Nova Science Pub Incorporated
ISBN: 9781631176579
Category : Science
Languages : en
Pages : 331

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Book Description
This is the first book specifically devoted to butyrate and its biological functions in the health of humans and animals. It is the result of the collective efforts of a group of international experts working on different aspects of butyrate. It has been recognised for a long time that the consumption of dietary fibres has positive metabolic health effects. These effects are directly associated with short-chain fatty acids (SCFAs), particularly butyrate, formed by the microbial degradation of dietary fibres in the digestive tract. Butyrate-induced biological effects provide examples of epigenomic regulation induced by nutrient elements and provide a basis for understanding the full range of the biological roles and molecular mechanisms that butyrate may play in cell growth, proliferation and energy metabolism. This book is a comprehensive collection of highly innovative research ideas, strategies, and crucial points related to butyrate and its biological functions. With a detailed introduction of recent advances in different but intriguing research fields, this book is a great reference for biochemists, molecular biologists, biomedical scientists and clinical researchers. This book is also a great reference for graduate students working in the related fields of biomedical sciences.

Phenolic Acids

Phenolic Acids PDF Author: Sergi Munné-Bosch
Publisher: Nova Biomedical
ISBN: 9781619420328
Category : Medical
Languages : en
Pages : 243

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Book Description
This book aims at introducing the non-specialist as well as the professionals in the fields of chemistry, biochemistry, biotechnology, food science and biomedical sciences into the biochemistry, applications and health benefits of an important group of natural products, phenolic acids. The book shows how phenolic acids display a potent antioxidant capacity and therefore health promoting effects and describe the phenolic acid composition in fruits and vegetables. The book also covers industrial applications related to phenolic acids. Furthermore, the book discusses the application of phenolic acids as food additives, since the preparation of foods with a high content of phenolic acids can lead to a reduction in the use of synthetic additives, resulting in healthier foods that can be included in the functional foods group. The book is of interest to specialists in the field but also to graduate or postgraduate students that are interested in this particular group of natural products.

Handbook on Protein Purification

Handbook on Protein Purification PDF Author: Nikolaos E. Labrou
Publisher:
ISBN: 9781536143652
Category : Science
Languages : en
Pages : 0

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Book Description
Proteins are important biomolecules that are vital for the cellular structure and function. They perform a vast array of functions within organisms, including the catalysis of metabolic reactions, DNA replication, response to stimuli, and transporting molecules from one location to another. The technological advances in the omics areas (e.g., genomics, transcriptomics, proteomics, metagenomics, etc.) have dramatically increased the rate of discovering new proteins. Some of them hold large opportunities for innovative research and the development of commercial products and applications. It is worth noting that the global protein ingredients market is poised to grow over the next decade to reach approximately 58.49 billion USD by 2022, with the protein therapeutics market valuing around USD 315.9 billion by 2025. Interestingly, about seventy monoclonal antibody products will be on the market by 2020 with a combined worldwide sales of about 125 billion USD.The most significant parameter for the successful commercial exploitation of proteins rely on the development of an efficient and effective isolation and purification technology, known as protein downstream processing. Downstream processing refers to the technology that involves the isolation and production of purified products from natural sources such as animal tissues, plant tissues, microorganisms or fermentation broth. The most important element of this technology is the high purification processes, most important of which is chromatography and in particular affinity chromatography.This book provides information on the resent developments of protein downstream processing and deals with the information gained over the last years from the application of protein purification technologies on different research areas. Each chapter gives key examples that cover a wide range of diverse scientific disciplines in order to provide the reader with a representative sample of the current status of the field. The present book would definitely be an ideal source of scientific information to the advanced students, junior researchers, and scientists involved in cellular and molecular biology, biochemistry, microbiology, biotechnology and other related areas.

Biochemistry and Biochemists: Who Were They and What Did They Discover?

Biochemistry and Biochemists: Who Were They and What Did They Discover? PDF Author: Manuel Varela
Publisher: Nova Science Publishers
ISBN: 9781536184938
Category : Biochemistry
Languages : en
Pages : 319

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Book Description
The book Biochemistry and Biochemists: Who Were They and What did they Discover is an series of twenty five reviews regarding the top twenty five biochemists of the last two hundred years. The book chronicles the work and discoveries of research scientists from various parts of the world (Severo Ochoa of Spain, John Earnest Walker of Great Britain, Luis Leloir of France, Jens Skou of Denmark as well Masayusa Nomura of Japan). Some of these biochemists did foundational work (Albert Szent-Gyorgy in the realm of vitamin C ) and others did exemplary work into some of the most important realms of their time ( such as Dorothy Hodgkin and her explorations into the structures of penicillin and insulin ). Enzyme kinetics was explored and researched by Maud Menten and Leonor Michaelis. The lives and explorations of these individuals as well as relevant anecdotes regarding their lives are explored in this book. For example, Jakub Karos Parnas, a well known scholar and researcher died in the famous Lyubyanka Prison in Moscow, although the exact cause of his death may never be known. Luis Leloir was born in the shadow of the Arc de Triomphe in Paris and went on to achieve greatness and crucial insights in sugar metabolism and glycogen biosynthesis. Some of these researchers investigated things as simple as water ( and their transporation into and out of cells ) and others offered such profound ideas such as Albert Kluyver and his comments that "all organisms do biochemistry". In a sense, all students of biochemistry as well as chemistry would do well to learn about these biochemists, their discoveries and a bit about their lives- as many led many challenging lives- such as escaping from the Germans in World War II. Each of the biochemists here in this text had something to offer the realm of science and many were rewarded with the highest honor imaginable- the Nobel Prize- and some of them succeeded in their chosen field of endeavor- even though they may have failed Anatomy and Physiology four times! Investigations into DNA, ATP and these realms also are highlighted in this book as these fundamental concepts are obviously of critical importance in the realm of biochemistry. This book is first a serious exploration into the discoveries of these biochemists while at the same time an interesting examination of the lives, and loves and trials and tribulations of these biochemists who literally changed the face of biochemistry over the years.

Xylose

Xylose PDF Author: Ping Xu
Publisher:
ISBN: 9781621007586
Category : Xylose
Languages : en
Pages : 0

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Book Description
Xylose is a sugar isolated from wood, and classified as a monosaccharide of the aldopentose type, which means that it contains five carbon atoms and includes an aldehyde functional group. It is the precursor to hemicellulose, one of the main constituents of biomass. Like most sugars, it can adopt several structures depending on conditions. This book presents topical research in the study of the production, consumption and health benefits of xylose including the manufacture, refining, and characterisation of oligosaccharides from lignocellulosic materials; xylose as a dietary sugar source; utilisation of xylose for producing bio-based fuels; use of D-Xylose in the green surfactant industry; xylitol production from xylose by a hyperacidophilic candida tropicalis using fed-batch fermentation strategy and enzymatic xylose release from wheat bran arabinoxylans.

Protein Hydrolysates

Protein Hydrolysates PDF Author: Sheri Sims
Publisher:
ISBN: 9781536148985
Category : Protein hydrolysates
Languages : en
Pages : 193

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Book Description
In this collection, the authors aim to provide information the preparation of marine protein hydrolysates and their main bioactive properties such as antioxidant, antimicrobial, antitumor and antihypertensive. Applications of these compounds in the area food technology and pharmaceuticals are also discussed.Protein Hydrolysates: Uses, Properties and Health Effects goes on to present some biological properties of fish peptides and their beneficial effects on health, emphasizing properties such as antidiabetic neuroprotective and anti-inflammatory, as a natural alternative to drugs and possible strategies to delay cognitive impairment.As confectionery manufacturers are trying to be innovative in producing suitable fat fillings for various applications. As such, the authors examine the functional, rheological and sensory properties of confectionery fat filling supplemented with different concentrations of bioactive whey protein hydrolysate powders, produced by enzymatic and microbial modification of whey proteins.Next, the bioactive potential of hydrolysate powders produced by enzymatic and microbial hydrolysis of whey proteins followed by spray drying is examined in order to determine which process allows for a highly bioactive production.A strain-substrate combination is introduced which allows for the production of dairy protein hydrolysates with high antioxidant activity and improved functional properties, which may be used as high-quality food supplements.The traditional methods for the production of functional peptides from biological sources are time-consuming and tedious. In the drug industry, it takes about five to ten years from the discovery of an industrial bioactive peptide to market delivery. To overcome the drawbacks of these traditional methods, the authors propose that a fast and versatile method is necessary.The concluding chapter presents an overview of the production and applications of bioactive peptides, demonstrating their potential use as helper agents of health processes. These peptides may aid in traditional health treatments since they can be used in high concentrations without associated toxic effects.