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Author: Azalea Ellis
Publisher: Seladore Publishing
ISBN:
Category : Fiction
Languages : en
Pages : 716
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Book Description
To study magic at the University, Siobhan sacrificed her name. She sacrificed her body, and her past. Magically disguised as a boy named Sebastien, she is learning wondrous secrets of the thaumaturgic sciences. As Sebastien, she mingles with the young nobles who will one day rule their country. But danger is closer than ever, and she cannot escape her past. The coppers investigating the theft of Siobhan's priceless transformation artifact have given her a new name. The Raven Queen. As Siobhan does favors for the gang that loaned her the University tuition, the Raven Queen's mystique only grows. And keeps growing... ...Snowballing out of control until Siobhan's other identity takes on a life of its own, a fear-inducing bogeyman well beyond the truth of her real capabilities. With the whole city out to get her and trouble hounding both sides of her double life, how will Siobhan ever survive to become the world's most powerful sorcerer?
Author: Azalea Ellis
Publisher: Seladore Publishing
ISBN:
Category : Fiction
Languages : en
Pages : 716
Get Book Here
Book Description
To study magic at the University, Siobhan sacrificed her name. She sacrificed her body, and her past. Magically disguised as a boy named Sebastien, she is learning wondrous secrets of the thaumaturgic sciences. As Sebastien, she mingles with the young nobles who will one day rule their country. But danger is closer than ever, and she cannot escape her past. The coppers investigating the theft of Siobhan's priceless transformation artifact have given her a new name. The Raven Queen. As Siobhan does favors for the gang that loaned her the University tuition, the Raven Queen's mystique only grows. And keeps growing... ...Snowballing out of control until Siobhan's other identity takes on a life of its own, a fear-inducing bogeyman well beyond the truth of her real capabilities. With the whole city out to get her and trouble hounding both sides of her double life, how will Siobhan ever survive to become the world's most powerful sorcerer?
Author: Ryan Cahill
Publisher:
ISBN: 9781838381806
Category :
Languages : en
Pages : 542
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Book Description
Of Blood and Fire is a classic Epic Fantasy adventure. It takes all the familiar fantasy tropes - elves, dwarves, giants, and dragons - and adds a fresh, contemporary twist.
Author: Roland N. Pittman
Publisher: Biota Publishing
ISBN: 1615047212
Category : Medical
Languages : en
Pages : 117
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Book Description
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Author: Linda S. Costanzo
Publisher: Elsevier Health Sciences
ISBN: 1455728136
Category : Medical
Languages : en
Pages : 517
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Book Description
Physiology is a comprehensive presentation of core physiologic concepts with a focus on mechanisms. Renowned physiology instructor Linda S. Costanzo covers important concepts in the field, both at the organ system and cellular levels. Easy to read and user-friendly, the revised fourth edition stresses essential and relevant content with absolute clarity and includes concise step-by-step explanations complemented by numerous tables and abundant illustrations. It provides information on the underlying principles of cellular physiology, the autonomic nervous system, and neurophysiology, as well as the cardiovascular, respiratory, renal, acid-base, gastrointestinal, endocrine, and reproductive organ systems. This book is ideal as both a textbook and as a review guide for the boards. Provides step-by-step explanations and easy-to-follow diagrams clearly depicting physiologic principles. Integrates equations and sample problems throughout the text. Presents chapter summaries for quick overviews of important points. Contains boxed Clinical Physiology Cases to provide you with more clinical examples and a more thorough understanding of application. Provides questions at the end of each chapter for an extensive review of the material and to reinforce your understanding and retention. Offers a full-color design and all full-color illustrations throughout. Features increased coverage of pathophysiology in the neurophysiology, gastrointestinal, renal, acid-base, and endocrine chapters to emphasize this important component of the USMLE exam. Incorporates further practice in solving physiology equations through the inclusion of additional problem-solving questions throughout the text.
Author: A. Wallace Hayes
Publisher: CRC Press
ISBN: 1842145363
Category : Medical
Languages : en
Pages : 2186
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Book Description
Hayes’ Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chapters that address the advances and developments since the fifth edition, the book presents everything toxicologists and students need to know to understand hazards and mechanisms of toxicity, enabling them to better assess risk. The book begins with the four basic principles of toxicology—dose matters, people differ, everything transforms, and timing is crucial. The contributors discuss various agents of toxicity, including foodborne, solvents, crop protection chemicals, radiation, and plant and animal toxins. They examine various methods for defining and measuring toxicity in a host of areas, including genetics, carcinogenicity, toxicity in major body systems, and the environment. This new edition contains an expanded glossary reflecting significant changes in the field. New topics in this edition include: The importance of dose–response Systems toxicology Food safety The humane use and care of animals Neurotoxicology The comprehensive coverage and clear writing style make this volume an invaluable text for students and a one-stop reference for professionals.
Author: Linda Costanzo
Publisher: Elsevier Health Sciences
ISBN: 0323511899
Category : Medical
Languages : en
Pages : 531
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Book Description
Renowned physiology instructor Dr. Linda Costanzo's friendly, logical, easy-to-follow writing style makes Physiology, 6th Edition ideal for coursework and USMLE preparation. Well-designed figures and tables provide handy visuals for procedures or physiologic equations, and step-by-step explanations clarify challenging concepts. This full-color, manageably-sized text offers a comprehensive and consistent overview of core physiologic concepts at the organ system and cellular levels, making complex principles easy to understand. - Information is presented in a short, simple, and focused manner – the perfect presentation for success in coursework and on exams. - Chapter summaries and "Challenge Yourself" questions at the end of each chapter provide an extensive review of the material and reinforce understanding and retention. - Equations and sample problems are integrated throughout the text. - NEW! More Clinical Physiology Case Boxes relate to pathophysiology for a clinical context. - Student Consult access includes high-yield student FAQs with thorough explanations, animations, and NEW video tutorials from Dr. Costanzo.
Author: Rodney Rhoades
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781768528
Category : Medical
Languages : en
Pages : 836
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Book Description
Now in its Third Edition, this text clearly and concisely presents the physiological principles that are essential to clinical medicine. Outstanding pedagogical features include Active Learning Objectives that emphasize problem-solving applications of basic principles; conceptual diagrams that help students visualize complex processes; case studies, Clinical Focus boxes, and From Bench to Bedside boxes; a comprehensive glossary; and online USMLE-style questions with answers and explanations. This edition features a new Immunology and Organ Function chapter and a completely rewritten and reorganized cardiovascular section. A companion Website will include the fully searchable text, an interactive question bank, case studies with practice questions, animations of complex processes, an image bank, and links for further study.
Author: Shayne Cox Gad
Publisher: John Wiley & Sons
ISBN: 0470249021
Category : Medical
Languages : en
Pages : 1352
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Book Description
A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for current methods and techniques. Each chapter is written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor has carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear. Among the key topics covered are: * Modeling and informatics in drug design * Bioanalytical chemistry * Absorption of drugs after oral administration * Transporter interactions in the ADME pathway of drugs * Metabolism kinetics * Mechanisms and consequences of drug-drug interactions Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage. This publication should be readily accessible to all pharmaceutical scientists involved in preclinical testing, enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin.
Author: David L. Nelson
Publisher: Macmillan
ISBN: 071677108X
Category : Science
Languages : en
Pages : 1303
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Book Description
Authors Dave Nelson and Mike Cox combine the best of the laboratory and best of the classroom, introducing exciting new developments while communicating basic principles of biochemistry.
Author: Donglu Zhang
Publisher: John Wiley & Sons
ISBN: 1118180763
Category : Science
Languages : en
Pages : 622
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Book Description
A comprehensive guide to cutting-edge tools in ADME research The last decade has seen tremendous progress in the development of analytical techniques such as mass spectrometry and molecular biology tools, resulting in important advances in drug discovery, particularly in the area of absorption, distribution, metabolism, and excretion (ADME). ADME-Enabling Technologies in Drug Design and Development focuses on the current state of the art in the field, presenting a comprehensive review of the latest tools for generating ADME data in drug discovery. It examines the broadest possible range of available technologies, giving readers the information they need to choose the right tool for a given application, a key requisite for obtaining favorable results in a timely fashion for regulatory filings. With over thirty contributed chapters by an international team of experts, the book provides: A thorough examination of current tools, covering both electronic/mechanical technologies and biologically based ones Coverage of applications for each technology, including key parameters, optimal conditions for intended results, protocols, and case studies Detailed discussion of emerging tools and techniques, from stem cells and genetically modified animal models to imaging technologies Numerous figures and diagrams throughout the text Scientists and researchers in drug metabolism, pharmacology, medicinal chemistry, pharmaceutics, toxicology, and bioanalytical science will find ADME-Enabling Technologies in Drug Design and Development an invaluable guide to the entire drug development process, from discovery to regulatory issues.
