Bayesian Thinking in Biostatistics

Bayesian Thinking in Biostatistics PDF Author: Gary L Rosner
Publisher: CRC Press
ISBN: 1000353001
Category : Mathematics
Languages : en
Pages : 564

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Book Description
Praise for Bayesian Thinking in Biostatistics: "This thoroughly modern Bayesian book ...is a 'must have' as a textbook or a reference volume. Rosner, Laud and Johnson make the case for Bayesian approaches by melding clear exposition on methodology with serious attention to a broad array of illuminating applications. These are activated by excellent coverage of computing methods and provision of code. Their content on model assessment, robustness, data-analytic approaches and predictive assessments...are essential to valid practice. The numerous exercises and professional advice make the book ideal as a text for an intermediate-level course..." -Thomas Louis, Johns Hopkins University "The book introduces all the important topics that one would usually cover in a beginning graduate level class on Bayesian biostatistics. The careful introduction of the Bayesian viewpoint and the mechanics of implementing Bayesian inference in the early chapters makes it a complete self- contained introduction to Bayesian inference for biomedical problems....Another great feature for using this book as a textbook is the inclusion of extensive problem sets, going well beyond construed and simple problems. Many exercises consider real data and studies, providing very useful examples in addition to serving as problems." - Peter Mueller, University of Texas With a focus on incorporating sensible prior distributions and discussions on many recent developments in Bayesian methodologies, Bayesian Thinking in Biostatistics considers statistical issues in biomedical research. The book emphasizes greater collaboration between biostatisticians and biomedical researchers. The text includes an overview of Bayesian statistics, a discussion of many of the methods biostatisticians frequently use, such as rates and proportions, regression models, clinical trial design, and methods for evaluating diagnostic tests. Key Features Applies a Bayesian perspective to applications in biomedical science Highlights advances in clinical trial design Goes beyond standard statistical models in the book by introducing Bayesian nonparametric methods and illustrating their uses in data analysis Emphasizes estimation of biomedically relevant quantities and assessment of the uncertainty in this estimation Provides programs in the BUGS language, with variants for JAGS and Stan, that one can use or adapt for one's own research The intended audience includes graduate students in biostatistics, epidemiology, and biomedical researchers, in general Authors Gary L. Rosner is the Eli Kennerly Marshall, Jr., Professor of Oncology at the Johns Hopkins School of Medicine and Professor of Biostatistics at the Johns Hopkins Bloomberg School of Public Health. Purushottam (Prakash) W. Laud is Professor in the Division of Biostatistics, and Director of the Biostatistics Shared Resource for the Cancer Center, at the Medical College of Wisconsin. Wesley O. Johnson is professor Emeritus in the Department of Statistics as the University of California, Irvine.

Bayesian Thinking in Biostatistics

Bayesian Thinking in Biostatistics PDF Author: Gary L Rosner
Publisher: CRC Press
ISBN: 1000353001
Category : Mathematics
Languages : en
Pages : 564

Get Book Here

Book Description
Praise for Bayesian Thinking in Biostatistics: "This thoroughly modern Bayesian book ...is a 'must have' as a textbook or a reference volume. Rosner, Laud and Johnson make the case for Bayesian approaches by melding clear exposition on methodology with serious attention to a broad array of illuminating applications. These are activated by excellent coverage of computing methods and provision of code. Their content on model assessment, robustness, data-analytic approaches and predictive assessments...are essential to valid practice. The numerous exercises and professional advice make the book ideal as a text for an intermediate-level course..." -Thomas Louis, Johns Hopkins University "The book introduces all the important topics that one would usually cover in a beginning graduate level class on Bayesian biostatistics. The careful introduction of the Bayesian viewpoint and the mechanics of implementing Bayesian inference in the early chapters makes it a complete self- contained introduction to Bayesian inference for biomedical problems....Another great feature for using this book as a textbook is the inclusion of extensive problem sets, going well beyond construed and simple problems. Many exercises consider real data and studies, providing very useful examples in addition to serving as problems." - Peter Mueller, University of Texas With a focus on incorporating sensible prior distributions and discussions on many recent developments in Bayesian methodologies, Bayesian Thinking in Biostatistics considers statistical issues in biomedical research. The book emphasizes greater collaboration between biostatisticians and biomedical researchers. The text includes an overview of Bayesian statistics, a discussion of many of the methods biostatisticians frequently use, such as rates and proportions, regression models, clinical trial design, and methods for evaluating diagnostic tests. Key Features Applies a Bayesian perspective to applications in biomedical science Highlights advances in clinical trial design Goes beyond standard statistical models in the book by introducing Bayesian nonparametric methods and illustrating their uses in data analysis Emphasizes estimation of biomedically relevant quantities and assessment of the uncertainty in this estimation Provides programs in the BUGS language, with variants for JAGS and Stan, that one can use or adapt for one's own research The intended audience includes graduate students in biostatistics, epidemiology, and biomedical researchers, in general Authors Gary L. Rosner is the Eli Kennerly Marshall, Jr., Professor of Oncology at the Johns Hopkins School of Medicine and Professor of Biostatistics at the Johns Hopkins Bloomberg School of Public Health. Purushottam (Prakash) W. Laud is Professor in the Division of Biostatistics, and Director of the Biostatistics Shared Resource for the Cancer Center, at the Medical College of Wisconsin. Wesley O. Johnson is professor Emeritus in the Department of Statistics as the University of California, Irvine.

Elementary Bayesian Biostatistics

Elementary Bayesian Biostatistics PDF Author: Lemuel A. Moye
Publisher: CRC Press
ISBN: 1584887257
Category : Mathematics
Languages : en
Pages : 400

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Book Description
Bayesian analyses have made important inroads in modern clinical research due, in part, to the incorporation of the traditional tools of noninformative priors as well as the modern innovations of adaptive randomization and predictive power. Presenting an introductory perspective to modern Bayesian procedures, Elementary Bayesian Biostatistics explo

Bayesian Data Analysis, Third Edition

Bayesian Data Analysis, Third Edition PDF Author: Andrew Gelman
Publisher: CRC Press
ISBN: 1439840954
Category : Mathematics
Languages : en
Pages : 677

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Book Description
Now in its third edition, this classic book is widely considered the leading text on Bayesian methods, lauded for its accessible, practical approach to analyzing data and solving research problems. Bayesian Data Analysis, Third Edition continues to take an applied approach to analysis using up-to-date Bayesian methods. The authors—all leaders in the statistics community—introduce basic concepts from a data-analytic perspective before presenting advanced methods. Throughout the text, numerous worked examples drawn from real applications and research emphasize the use of Bayesian inference in practice. New to the Third Edition Four new chapters on nonparametric modeling Coverage of weakly informative priors and boundary-avoiding priors Updated discussion of cross-validation and predictive information criteria Improved convergence monitoring and effective sample size calculations for iterative simulation Presentations of Hamiltonian Monte Carlo, variational Bayes, and expectation propagation New and revised software code The book can be used in three different ways. For undergraduate students, it introduces Bayesian inference starting from first principles. For graduate students, the text presents effective current approaches to Bayesian modeling and computation in statistics and related fields. For researchers, it provides an assortment of Bayesian methods in applied statistics. Additional materials, including data sets used in the examples, solutions to selected exercises, and software instructions, are available on the book’s web page.

Bayesian Methods in Epidemiology

Bayesian Methods in Epidemiology PDF Author: Lyle D. Broemeling
Publisher: CRC Press
ISBN: 1466564989
Category : Mathematics
Languages : en
Pages : 464

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Book Description
Written by a biostatistics expert with over 20 years of experience in the field, Bayesian Methods in Epidemiology presents statistical methods used in epidemiology from a Bayesian viewpoint. It employs the software package WinBUGS to carry out the analyses and offers the code in the text and for download online.The book examines study designs that

Bayesian Adaptive Methods for Clinical Trials

Bayesian Adaptive Methods for Clinical Trials PDF Author: Scott M. Berry
Publisher: CRC Press
ISBN: 1439825513
Category : Mathematics
Languages : en
Pages : 316

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Book Description
Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer's disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV. Written by leading pioneers of Bayesian clinical trial designs, Bayesian Adapti

A First Course in Bayesian Statistical Methods

A First Course in Bayesian Statistical Methods PDF Author: Peter D. Hoff
Publisher: Springer Science & Business Media
ISBN: 0387924078
Category : Mathematics
Languages : en
Pages : 270

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Book Description
A self-contained introduction to probability, exchangeability and Bayes’ rule provides a theoretical understanding of the applied material. Numerous examples with R-code that can be run "as-is" allow the reader to perform the data analyses themselves. The development of Monte Carlo and Markov chain Monte Carlo methods in the context of data analysis examples provides motivation for these computational methods.

Let the Evidence Speak

Let the Evidence Speak PDF Author: Alan Jessop
Publisher: Springer
ISBN: 3319713922
Category : Mathematics
Languages : en
Pages : 220

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Book Description
This book presents the most important ideas behind Bayes’ Rule in a form suitable for the general reader. It is written without formulae because they are not necessary; the ability to add and multiply is all that is needed. As well as showing in full the application of Bayes’ Rule to some quantitatively simple, though not trivial, examples, the book also convincingly demonstrates that some familiarity with Bayes’ Rule is helpful in thinking about how best to structure one’s thinking.

Bayesian Survival Analysis

Bayesian Survival Analysis PDF Author: Joseph G. Ibrahim
Publisher: Springer Science & Business Media
ISBN: 1475734476
Category : Medical
Languages : en
Pages : 494

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Book Description
Survival analysis arises in many fields of study including medicine, biology, engineering, public health, epidemiology, and economics. This book provides a comprehensive treatment of Bayesian survival analysis. It presents a balance between theory and applications, and for each class of models discussed, detailed examples and analyses from case studies are presented whenever possible. The applications are all from the health sciences, including cancer, AIDS, and the environment.

Bayes Rules!

Bayes Rules! PDF Author: Alicia A. Johnson
Publisher: CRC Press
ISBN: 1000529568
Category : Mathematics
Languages : en
Pages : 606

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Book Description
Praise for Bayes Rules!: An Introduction to Applied Bayesian Modeling “A thoughtful and entertaining book, and a great way to get started with Bayesian analysis.” Andrew Gelman, Columbia University “The examples are modern, and even many frequentist intro books ignore important topics (like the great p-value debate) that the authors address. The focus on simulation for understanding is excellent.” Amy Herring, Duke University “I sincerely believe that a generation of students will cite this book as inspiration for their use of – and love for – Bayesian statistics. The narrative holds the reader’s attention and flows naturally – almost conversationally. Put simply, this is perhaps the most engaging introductory statistics textbook I have ever read. [It] is a natural choice for an introductory undergraduate course in applied Bayesian statistics." Yue Jiang, Duke University “This is by far the best book I’ve seen on how to (and how to teach students to) do Bayesian modeling and understand the underlying mathematics and computation. The authors build intuition and scaffold ideas expertly, using interesting real case studies, insightful graphics, and clear explanations. The scope of this book is vast – from basic building blocks to hierarchical modeling, but the authors’ thoughtful organization allows the reader to navigate this journey smoothly. And impressively, by the end of the book, one can run sophisticated Bayesian models and actually understand the whys, whats, and hows.” Paul Roback, St. Olaf College “The authors provide a compelling, integrated, accessible, and non-religious introduction to statistical modeling using a Bayesian approach. They outline a principled approach that features computational implementations and model assessment with ethical implications interwoven throughout. Students and instructors will find the conceptual and computational exercises to be fresh and engaging.” Nicholas Horton, Amherst College An engaging, sophisticated, and fun introduction to the field of Bayesian statistics, Bayes Rules!: An Introduction to Applied Bayesian Modeling brings the power of modern Bayesian thinking, modeling, and computing to a broad audience. In particular, the book is an ideal resource for advanced undergraduate statistics students and practitioners with comparable experience. Bayes Rules! empowers readers to weave Bayesian approaches into their everyday practice. Discussions and applications are data driven. A natural progression from fundamental to multivariable, hierarchical models emphasizes a practical and generalizable model building process. The evaluation of these Bayesian models reflects the fact that a data analysis does not exist in a vacuum. Features • Utilizes data-driven examples and exercises. • Emphasizes the iterative model building and evaluation process. • Surveys an interconnected range of multivariable regression and classification models. • Presents fundamental Markov chain Monte Carlo simulation. • Integrates R code, including RStan modeling tools and the bayesrules package. • Encourages readers to tap into their intuition and learn by doing. • Provides a friendly and inclusive introduction to technical Bayesian concepts. • Supports Bayesian applications with foundational Bayesian theory.

Regression Modeling Strategies

Regression Modeling Strategies PDF Author: Frank E. Harrell
Publisher: Springer Science & Business Media
ISBN: 147573462X
Category : Mathematics
Languages : en
Pages : 583

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Book Description
Many texts are excellent sources of knowledge about individual statistical tools, but the art of data analysis is about choosing and using multiple tools. Instead of presenting isolated techniques, this text emphasizes problem solving strategies that address the many issues arising when developing multivariable models using real data and not standard textbook examples. It includes imputation methods for dealing with missing data effectively, methods for dealing with nonlinear relationships and for making the estimation of transformations a formal part of the modeling process, methods for dealing with "too many variables to analyze and not enough observations," and powerful model validation techniques based on the bootstrap. This text realistically deals with model uncertainty and its effects on inference to achieve "safe data mining".