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Author: Gianluca Baio
Publisher: Springer
ISBN: 3319557181
Category : Medical
Languages : en
Pages : 181
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Book Description
The book provides a description of the process of health economic evaluation and modelling for cost-effectiveness analysis, particularly from the perspective of a Bayesian statistical approach. Some relevant theory and introductory concepts are presented using practical examples and two running case studies. The book also describes in detail how to perform health economic evaluations using the R package BCEA (Bayesian Cost-Effectiveness Analysis). BCEA can be used to post-process the results of a Bayesian cost-effectiveness model and perform advanced analyses producing standardised and highly customisable outputs. It presents all the features of the package, including its many functions and their practical application, as well as its user-friendly web interface. The book is a valuable resource for statisticians and practitioners working in the field of health economics wanting to simplify and standardise their workflow, for example in the preparation of dossiers in support of marketing authorisation, or academic and scientific publications.
Author: Gianluca Baio
Publisher: Springer
ISBN: 3319557181
Category : Medical
Languages : en
Pages : 181
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Book Description
The book provides a description of the process of health economic evaluation and modelling for cost-effectiveness analysis, particularly from the perspective of a Bayesian statistical approach. Some relevant theory and introductory concepts are presented using practical examples and two running case studies. The book also describes in detail how to perform health economic evaluations using the R package BCEA (Bayesian Cost-Effectiveness Analysis). BCEA can be used to post-process the results of a Bayesian cost-effectiveness model and perform advanced analyses producing standardised and highly customisable outputs. It presents all the features of the package, including its many functions and their practical application, as well as its user-friendly web interface. The book is a valuable resource for statisticians and practitioners working in the field of health economics wanting to simplify and standardise their workflow, for example in the preparation of dossiers in support of marketing authorisation, or academic and scientific publications.
Author: Gianluca Baio
Publisher: CRC Press
ISBN: 1439895562
Category : Mathematics
Languages : en
Pages : 242
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Book Description
Health economics is concerned with the study of the cost-effectiveness of health care interventions. This book provides an overview of Bayesian methods for the analysis of health economic data. After an introduction to the basic economic concepts and methods of evaluation, it presents Bayesian statistics using accessible mathematics. The next chapters describe the theory and practice of cost-effectiveness analysis from a statistical viewpoint, and Bayesian computation, notably MCMC. The final chapter presents three detailed case studies covering cost-effectiveness analyses using individual data from clinical trials, evidence synthesis and hierarchical models and Markov models. The text uses WinBUGS and JAGS with datasets and code available online.
Author: Jean-Michel Marin
Publisher: Springer Science & Business Media
ISBN: 1461486874
Category : Computers
Languages : en
Pages : 305
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Book Description
This Bayesian modeling book provides a self-contained entry to computational Bayesian statistics. Focusing on the most standard statistical models and backed up by real datasets and an all-inclusive R (CRAN) package called bayess, the book provides an operational methodology for conducting Bayesian inference, rather than focusing on its theoretical and philosophical justifications. Readers are empowered to participate in the real-life data analysis situations depicted here from the beginning. Special attention is paid to the derivation of prior distributions in each case and specific reference solutions are given for each of the models. Similarly, computational details are worked out to lead the reader towards an effective programming of the methods given in the book. In particular, all R codes are discussed with enough detail to make them readily understandable and expandable. Bayesian Essentials with R can be used as a textbook at both undergraduate and graduate levels. It is particularly useful with students in professional degree programs and scientists to analyze data the Bayesian way. The text will also enhance introductory courses on Bayesian statistics. Prerequisites for the book are an undergraduate background in probability and statistics, if not in Bayesian statistics.
Author: Parteek Bhatia
Publisher: Cambridge University Press
ISBN: 110858585X
Category : Computers
Languages : en
Pages : 514
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Book Description
Written in lucid language, this valuable textbook brings together fundamental concepts of data mining and data warehousing in a single volume. Important topics including information theory, decision tree, Naïve Bayes classifier, distance metrics, partitioning clustering, associate mining, data marts and operational data store are discussed comprehensively. The textbook is written to cater to the needs of undergraduate students of computer science, engineering and information technology for a course on data mining and data warehousing. The text simplifies the understanding of the concepts through exercises and practical examples. Chapters such as classification, associate mining and cluster analysis are discussed in detail with their practical implementation using Weka and R language data mining tools. Advanced topics including big data analytics, relational data models and NoSQL are discussed in detail. Pedagogical features including unsolved problems and multiple-choice questions are interspersed throughout the book for better understanding.
Author: Andrea Klonschinski
Publisher: Routledge
ISBN: 1317291816
Category : Business & Economics
Languages : en
Pages : 293
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Book Description
The question of how to allocate scarce medical resources has become an important public policy issue in recent decades. Cost-utility analysis is the most commonly used method for determining the allocation of these resources, but this book counters the argument that overcoming its inherent imbalances is simply a question of implementing methodological changes. The Economics of Resource Allocation in Health Care represents the first comprehensive analysis of equity weighting in health care resource allocation that offers a fundamental critique of its basic framework. It offers a critique of health economics, putting the discourse on economic evaluation into its broader socio-political context. Such an approach broadens the debate on fairness in health economics and ties it in with deeper-rooted problems in moral philosophy. Ultimately, this interdisciplinary study calls for the adoption of a fundamentally different paradigm to address the distribution of scarce medical resources. This book will be of interest to policy makers, health care professionals, and post-graduate students looking to broaden their understanding of the economics of the health care system.
Author: Richard Cookson
Publisher:
ISBN: 0198838190
Category : Business & Economics
Languages : en
Pages : 385
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Book Description
Distributional cost-effectiveness analysis aims to help healthcare and public health organizations make fairer decisions with better outcomes. It can provide information about equity in the distribution of costs and effects - who gains, who loses, and by how much - and the trade-offs that sometimes occur between equity and efficiency. This is a practical guide to methods for quantifying the equity impacts of health programmes in high, middle, and low-income countries. The methods can be tailored to analyse different equity concerns in different decision making contexts. The handbook provides both hands-on training for postgraduate students and analysts and an accessible guide for academics, practitioners, managers, policymakers, and stakeholders. Part I is an introduction and overview for research commissioners, users, and producers. Parts II and III provide step-by-step guidance on how to simulate and evaluate distributions, with accompanying spreadsheet training exercises. Part IV concludes with discussions about how to handle uncertainty about facts and disagreement about values, and the future challenges facing this growing field. Book jacket.
Author: Zhong-Lin Lu
Publisher: MIT Press
ISBN: 0262019450
Category : Science
Languages : en
Pages : 473
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Book Description
A comprehensive treatment of the skills and techniques needed for visual psychophysics, from basic tools to sophisticated data analysis. Vision is one of the most active areas in biomedical research, and visual psychophysical techniques are a foundational methodology for this research enterprise. Visual psychophysics, which studies the relationship between the physical world and human behavior, is a classical field of study that has widespread applications in modern vision science. Bridging the gap between theory and practice, this textbook provides a comprehensive treatment of visual psychophysics, teaching not only basic techniques but also sophisticated data analysis methodologies and theoretical approaches. It begins with practical information about setting up a vision lab and goes on to discuss the creation, manipulation, and display of visual images; timing and integration of displays with measurements of brain activities and other relevant techniques; experimental designs; estimation of behavioral functions; and examples of psychophysics in applied and clinical settings. The book's treatment of experimental designs presents the most commonly used psychophysical paradigms, theory-driven psychophysical experiments, and the analysis of these procedures in a signal-detection theory framework. The book discusses the theoretical underpinnings of data analysis and scientific interpretation, presenting data analysis techniques that include model fitting, model comparison, and a general framework for optimized adaptive testing methods. It includes many sample programs in Matlab with functions from Psychtoolbox, a free toolbox for real-time experimental control. Once students and researchers have mastered the material in this book, they will have the skills to apply visual psychophysics to cutting-edge vision science.
Author: Andrew Briggs
Publisher: OUP Oxford
ISBN: 0191004952
Category : Medical
Languages : en
Pages : 269
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Book Description
In financially constrained health systems across the world, increasing emphasis is being placed on the ability to demonstrate that health care interventions are not only effective, but also cost-effective. This book deals with decision modelling techniques that can be used to estimate the value for money of various interventions including medical devices, surgical procedures, diagnostic technologies, and pharmaceuticals. Particular emphasis is placed on the importance of the appropriate representation of uncertainty in the evaluative process and the implication this uncertainty has for decision making and the need for future research. This highly practical guide takes the reader through the key principles and approaches of modelling techniques. It begins with the basics of constructing different forms of the model, the population of the model with input parameter estimates, analysis of the results, and progression to the holistic view of models as a valuable tool for informing future research exercises. Case studies and exercises are supported with online templates and solutions. This book will help analysts understand the contribution of decision-analytic modelling to the evaluation of health care programmes. ABOUT THE SERIES: Economic evaluation of health interventions is a growing specialist field, and this series of practical handbooks will tackle, in-depth, topics superficially addressed in more general health economics books. Each volume will include illustrative material, case histories and worked examples to encourage the reader to apply the methods discussed, with supporting material provided online. This series is aimed at health economists in academia, the pharmaceutical industry and the health sector, those on advanced health economics courses, and health researchers in associated fields.
Author: Elias Moreno
Publisher: CRC Press
ISBN: 1351744372
Category : Medical
Languages : en
Pages : 301
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Book Description
Cost-effectiveness analysis is becoming an increasingly important tool for decision making in the health systems. Cost-Effectiveness of Medical Treatments formulates the cost-effectiveness analysis as a statistical decision problem, identifies the sources of uncertainty of the problem, and gives an overview of the frequentist and Bayesian statistical approaches for decision making. Basic notions on decision theory such as space of decisions, space of nature, utility function of a decision and optimal decisions, are explained in detail using easy to read mathematics. Features Focuses on cost-effectiveness analysis as a statistical decision problem and applies the well-established optimal statistical decision methodology. Discusses utility functions for cost-effectiveness analysis. Enlarges the class of models typically used in cost-effectiveness analysis with the incorporation of linear models to account for covariates of the patients. This permits the formulation of the group (or subgroup) theory. Provides Bayesian procedures to account for model uncertainty in variable selection for linear models and in clustering for models for heterogeneous data. Model uncertainty in cost-effectiveness analysis has not been considered in the literature. Illustrates examples with real data. In order to facilitate the practical implementation of real datasets, provides the codes in Mathematica for the proposed methodology. The motivation for the book is to make the achievements in cost-effectiveness analysis accessible to health providers, who need to make optimal decisions, to the practitioners and to the students of health sciences. Elías Moreno is Professor of Statistics and Operational Research at the University of Granada, Spain, Corresponding Member of the Royal Academy of Sciences of Spain, and elect member of ISI. Francisco José Vázquez-Polo is Professor of Mathematics and Bayesian Methods at the University of Las Palmas de Gran Canaria, and Head of the Department of Quantitative Methods. Miguel Ángel Negrín is Senior Lecturer in the Department of Quantitative Methods at the ULPGC. His main research topics are Bayesian methods applied to Health Economics, economic evaluation and cost-effectiveness analysis, meta-analysis and equity in the provision of healthcare services.
Author: Anna Heath
Publisher: CRC Press
ISBN: 1003825583
Category : Mathematics
Languages : en
Pages : 280
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Book Description
Value of Information for Healthcare Decision-Making introduces the concept of Value of Information (VOI) use in health policy decision-making to determine the sensitivity of decisions to assumptions, and to prioritise and design future research. These methods, and their use in cost-effectiveness analysis, are increasingly acknowledged by health technology assessment authorities as vital. Key Features: Provides a comprehensive overview of VOI Simplifies VOI Showcases state-of-the-art techniques for computing VOI Includes R statistical software package Provides results when using VOI methods Uses realistic decision model to illustrate key concepts The primary audience for this book is health economic modellers and researchers, in industry, government, or academia, who wish to perform VOI analysis in health economic evaluations. It is relevant for postgraduate researchers and students in health economics or medical statistics who are required to learn the principles of VOI or undertake VOI analyses in their projects. The overall goal is to improve the understanding of these methods and make them easier to use.
