Basic Science of Spinal Diseases PDF Download
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Author: Alok D Sharan
Publisher: JP Medical Ltd
ISBN: 9350904691
Category : Medical
Languages : en
Pages : 310
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Book Description
This book is a comprehensive guide to the basic science of spinal diseases for trainees and clinicians. Divided into four sections, the authors begin with detailed discussion on the anatomy, physiology and pathophysiology of the intervertebral disc. The following sections examine the science of spinal instrumentation and spinal interventions. Clinical chapters are structured in a uniform format, beginning with the presentation of a clinical case, followed by detailed discussion and supporting evidence. Each case ends with challenging questions to direct further investigation. This book is a highly useful compilation of research work from recognised surgeons from the USA and The Netherlands, specialising in the fields of physiology, biology, biomechanics and mechanobiology. Key points Comprehensive guide to the basic science of spinal diseases Based on research work of specialists in physiology, biology, biomechanics and mechanobiology US and Dutch author and editor team Includes nearly 240 full colour images and illustrations
Author: Norbert Boos
Publisher: Springer Science & Business Media
ISBN: 3540690913
Category : Medical
Languages : en
Pages : 1162
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Book Description
Spinal disorders are among the most common medical conditions with significant impact on health related quality of life, use of health care resources and socio-economic costs. This is an easily readable teaching tool focusing on fundamentals and basic principles and provides a homogeneous syllabus with a consistent didactic strategy. The chosen didactic concept highlights and repeats core messages throughout the chapters. This textbook, with its appealing layout, will inspire and stimulate the reader for the study of spinal disorders.
Author: J. D. Bartleson
Publisher: Cambridge University Press
ISBN: 0521889413
Category : Medical
Languages : en
Pages : 303
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Book Description
An essential information source for all healthcare providers treating patients with cervical, thoracic and lumbar spine disease.
Author: Luigi Ambrosio
Publisher: Elsevier
ISBN: 0857096192
Category : Medical
Languages : en
Pages : 645
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Book Description
There have been important developments in materials and therapies for the treatment of spinal conditions. Biomaterials for spinal surgery summarises this research and how it is being applied for the benefit of patients.After an introduction to the subject, part one reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery. Part two discusses the use of bone substitutes and artificial intervertebral discs whilst part three covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty as well as scoliosis implants. The final part of the book summarises developments in regenerative therapies such as the use of stem cells for intervertebral disc regeneration.With its distinguished editors and international team of contributors, Biomaterials for spinal surgery is a standard reference for both those developing new biomaterials and therapies for spinal surgery and those using them in clinical practice. - Summarises recent developments in materials and therapies for the treatment of spinal conditions and examines how it is being applied for the benefit of patients - Reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery - Discusses the use of bone substitutes and artificial intervertebral discs and covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty
Author: Mark H. Tuszynski
Publisher: Elsevier
ISBN: 0080529216
Category : Science
Languages : en
Pages : 713
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Book Description
CNS Regeneration focuses on some of the leading current neurological disease models and methods for promoting central nervous system regeneration. Editors and authors are experts in the field, with experience in basic as well as applied neuroscience. In a comprehensive, logical manner, the book unites important basic science advances in neuroscience with novel medical strategies. - The first comprehensive, authoritative volume on the topic of CNS regeneration - Reviews current therapeutic approaches - Editors and authors are experts in the field - Appeals to those interested in basic science as well as those concerned with its medical application
Author: Charlotte J Sumner
Publisher: Academic Press
ISBN: 0128036869
Category : Medical
Languages : en
Pages : 508
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Book Description
Spinal Muscular Atrophy: Disease Mechanisms and Therapy provides the latest information on a condition that is characterized by motoneuron loss and muscle atrophy, and is the leading genetic cause of infant mortality. Since the identification of the gene responsible for SMA in 1995, there have been important advances in the basic understanding of disease mechanisms, and in therapeutic development. This book provides a comprehensive accounting of recent advances in basic and clinical research that covers SMA clinical features and standards of care, multifaceted aspects of SMN protein functions and SMA disease pathology, various animal models, and biomarkers, as well as current therapeutic development. This title is ideal for graduate students/postdocs and principal investigators who are already in the SMA field and need to keep updated on recent findings and approaches, and for those who are new to, or would like to join, the field. Likewise, users will find an excellent source of reading for biotech/pharma scientists, clinical researchers, and practitioners, regulators, and patients and their advocacy organizations. Furthermore, this book is a handy reference for researchers and clinicians who may want to apply the research strategies and therapeutic approaches in SMA to other rare diseases. - Provides comprehensive, up-to-date reviews by leading investigators on diverse topics of SMA, including clinical features and patient care, SMN genetics and protein functions, animal models, disease pathology and mechanisms, biomarkers, current therapeutic development, and the role of non-profit organizations in therapeutic development - Written to bridge multiple disciplines and promote better communications among basic scientists, clinical researchers, and health care providers on the latest developments in SMA - Includes outstanding questions and perspectives for future investigations and key references for additional detailed study
Author: Harry B. Skinner
Publisher:
ISBN: 9780071104517
Category : Orthopedic surgery
Languages : en
Pages : 756
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Book Description
Offers fingertip access to the diagnostic tools necessary for the definitive diagnosis and treatment of the most common musculo-skeletal disorders found in adults and children.
Author: Emmanuel Pierrot-Deseilligny
Publisher: Cambridge University Press
ISBN: 9781139445641
Category : Medical
Languages : en
Pages : 676
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Book Description
Studies of human movement have proliferated in recent years, and there have been many studies of spinal pathways in humans, their role in movement, and their dysfunction in neurological disorders. This comprehensive reference surveys the literature related to the control of spinal cord circuits in human subjects, showing how they can be studied, their role in normal movement, and how they malfunction in disease states. Chapters are highly illustrated and consistently organised, reviewing, for each pathway, the experimental background, methodology, organisation and control, role during motor tasks, and changes in patients with CNS lesions. Each chapter concludes with a helpful resume that can be used independently of the main text to provide practical guidance for clinical studies. This will be essential reading for research workers and clinicians involved in the study, treatment and rehabilitation of movement disorders.
Author: Susan J. Harkema
Publisher:
ISBN: 0195342089
Category : Medical
Languages : en
Pages : 200
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Book Description
Physical rehabilitation for walking recovery after spinal cord injury is undergoing a paradigm shift. Therapy historically has focused on compensation for sensorimotor deficits after SCI using wheelchairs and bracing to achieve mobility. With locomotor training, the aim is to promote recovery via activation of the neuromuscular system below the level of the lesion. What basic scientists have shown us as the potential of the nervous system for plasticity, to learn, even after injury is being translated into a rehabilitation strategy by taking advantage of the intrinsic biology of the central nervous system. While spinal cord injury from basic and clinical perspectives was the gateway for developing locomotor training, its application has been extended to other populations with neurologic dysfunction resulting in loss of walking or walking disability.
Author: Harald Sontheimer
Publisher: Academic Press
ISBN: 0128004037
Category : Medical
Languages : en
Pages : 533
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Book Description
The study of the brain continues to expand at a rapid pace providing fascinating insights into the basic mechanisms underlying nervous system illnesses. New tools, ranging from genome sequencing to non-invasive imaging, and research fueled by public and private investment in biomedical research has been transformative in our understanding of nervous system diseases and has led to an explosion of published primary research articles. Diseases of the Nervous System summarizes the current state of basic and clinical knowledge for the most common neurological and neuropsychiatric conditions. In a systematic progression, each chapter covers either a single disease or a group of related disorders ranging from static insults to primary and secondary progressive neurodegenerative diseases, neurodevelopmental illnesses, illnesses resulting from nervous system infection and neuropsychiatric conditions. Chapters follow a common format and are stand-alone units, each covering disease history, clinical presentation, disease mechanisms and treatment protocols. Dr. Sontheimer also includes two chapters which discuss common concepts shared among the disorders and how new findings are being translated from the bench to the bedside. In a final chapter, he explains the most commonly used neuroscience jargon. The chapters address controversial issues in current day neuroscience research including translational research, drug discovery, ethical issues, and the promises of personalized medicine. This book provides an introduction for course adoption and an introductory tutorial for students, scholars, researchers and medical professionals interested in learning the state of the art concerning our understanding and treatment of diseases of the nervous system. - 2016 PROSE Award winner of the Best Textbook Award in Biological & Life Sciences - Provides a focused tutorial introduction to the core diseases of the nervous system - Includes comprehensive introductions to Stroke, Epilepsy, Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, ALS, Head and Spinal Cord Trauma, Multiple Sclerosis, Brain Tumors, Depression, Schizophrenia and many other diseases of the nervous system - Covers more than 40 diseases from the foundational science to the best treatment protocols - Includes discussions of translational research, drug discovery, personalized medicine, ethics, and neuroscience
Author: Fabio Galbusera
Publisher: Academic Press
ISBN: 0128128526
Category : Technology & Engineering
Languages : en
Pages : 458
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Book Description
Biomechanics of the Spine encompasses the basics of spine biomechanics, spinal tissues, spinal disorders and treatment methods. Organized into four parts, the first chapters explore the functional anatomy of the spine, with special emphasis on aspects which are biomechanically relevant and quite often neglected in clinical literature. The second part describes the mechanics of the individual spinal tissues, along with commonly used testing set-ups and the constitutive models used to represent them in mathematical studies. The third part covers in detail the current methods which are used in spine research: experimental testing, numerical simulation and in vivo studies (imaging and motion analysis). The last part covers the biomechanical aspects of spinal pathologies and their surgical treatment. This valuable reference is ideal for bioengineers who are involved in spine biomechanics, and spinal surgeons who are looking to broaden their biomechanical knowledge base. The contributors to this book are from the leading institutions in the world that are researching spine biomechanics. - Includes broad coverage of spine disorders and surgery with a biomechanical focus - Summarizes state-of-the-art and cutting-edge research in the field of spine biomechanics - Discusses a variety of methods, including In vivo and In vitro testing, and finite element and musculoskeletal modeling
