Basic and Clinical Aspects of Cardiac Dynamics PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Basic and Clinical Aspects of Cardiac Dynamics PDF full book. Access full book title Basic and Clinical Aspects of Cardiac Dynamics by Jan Baan. Download full books in PDF and EPUB format.
Author: Jan Baan
Publisher: Elsevier Science & Technology
ISBN:
Category : Cardiovascular system
Languages : en
Pages : 66
Get Book Here
Book Description
Author: Jan Baan
Publisher: Elsevier Science & Technology
ISBN:
Category : Cardiovascular system
Languages : en
Pages : 66
Get Book Here
Book Description
Author: Jan Baan
Publisher:
ISBN:
Category :
Languages : en
Pages :
Get Book Here
Book Description
Author:
Publisher:
ISBN: 9780444900371
Category : Cardiovascular system
Languages : en
Pages : 54
Get Book Here
Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 54
Get Book Here
Book Description
Author: Jan Baan
Publisher:
ISBN:
Category :
Languages : en
Pages : 54
Get Book Here
Book Description
Author: Herbert J. Levine
Publisher: Springer
ISBN: 9781461296287
Category : Medical
Languages : en
Pages : 345
Get Book Here
Book Description
Cardiac anatomy had already been a subject of and its control in health and disease has been great interest for centuries when Harvey de published. Studies of hypertrophy, heart failure, scribed the dynamic nature of blood flow, but ischemia, and infarction have been vigorously the concept of defining ventricular function was pursued in experimental animals and in human first introduced with the measurement of a subjects, and as a result new areas for study have emerged. These include the process of hypertro mare's blood pressure by Steven Hales in 1733. Amidst the important contributions of a number phy as an adaptive mechanism, the coronary vas of European physiologists, the primal relation cular reserve in hypertrophy, the role of the ship between the mechanical energy of the heart microvasculature in myocardial failure, active and the length of a myocardial fiber was enun relaxation and other diastolic mechanisms that contribute to the syndrome of congestive heart ciated by E. H. Starling in 1912; this became known as the "law of the heart. " Perhaps the failure, ventricular interaction and the role of the normal pericardium, ischemic-stunned first major refinement of this law was suggested by Sarnoff and co-workers, who introduced the reperfused myocardium, and vasoactive drugs in concept of homeometric autoregulation to ex the treatment of heart failure.
Author: J. Baan
Publisher: Springer Science & Business Media
ISBN: 940098796X
Category : Medical
Languages : en
Pages : 539
Get Book Here
Book Description
Cardiac Dynamics is the name of a relatively young field of study, born from the fruitful interaction between branches of two different disciplines: medicine and physics. "Dynamics" is the branch of physics which deals with the action of forces on bodies or particles in motion or at rest. "Cardiac" relates to the clinical field of cardiology but also to cardiophysiology, both of which are specialized branches of medicine. Narrower than the well established field of Hemodynamics, Cardiac Dynamics is restricted to dynamic phenomena occurring in and around the heart. The mathematical treatment of such phenomena, however, is vastly more complex because of the intricate nature of the mechanisms involved in the cardiac action. Thus, whereas hemodynamics is concerned with predominantly passive (visco-) elastic structures - vessels - containing time-variant flow of viscous flui- blood -, the mechanical study of the heart requires additional con siderations such as: active elastic components representing the contractile mechanism of cardiac muscle, complex geometry and fiber structure in the myocardial wall, autoregulatory mechanisms, and intricate flow patterns associated with valve motion. Viewed in this light it is not surprising that attempts to describe ventricular pump function and to quantify contractile performance have not reached the level of sophistication which is common in e. g. arterial hemodynamics. For the same reason, many of the often simplified approaches to describe ventricular mechanics failed to stand up to more rigorous theoretical, experimental or clinical testing.
Author: R. John Solaro
Publisher: Biota Publishing
ISBN: 1615041753
Category : Medical
Languages : en
Pages : 46
Get Book Here
Book Description
Contractility describes the relative ability of the heart to eject a stroke volume (SV) at a given prevailing afterload (arterial pressure) and preload (end-diastolic volume; EDV). Various measures of contractility are related to the fraction as the SV/EDV or the ejection fraction, and the dynamics of ejection as determined from maximum pressure rise in the ventricles or arteries or from aortic flow velocities determined by echocardiography. At the cellular level, the ultimate determinant of contractility is the relative tension generation and shortening capability of the molecular motors (myosin cross-bridges) of the sarcomeres as determined by the rates and extent of Ca activation, the turnover kinetics of the cross-bridges, and the relative Ca responsiveness of the sarcomeres. Engagement of the regulatory signaling cascades controlling contractility occurs with occupancy and signal transduction by receptors for neurohumors of the autonomic nervous system as well as growth and stress signaling pathways. Contractility is also determined by the prevailing conditions of pH, temperature, and redox state. Short-term control of contractility is fully expressed during exercise. In long-term responses to stresses on the heart, contractility is modified by cellular remodeling and altered signaling that may compensate for a time but which ultimately may fail, leading to disorders.
Author: Michitoshi Inoue
Publisher: Springer Science & Business Media
ISBN: 4431683674
Category : Medical
Languages : en
Pages : 330
Get Book Here
Book Description
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
