Bacteria-cytokine Interactions in Health and Disease

Bacteria-cytokine Interactions in Health and Disease PDF Author: Brian Henderson
Publisher: Ashgate Publishing
ISBN:
Category : Medical
Languages : en
Pages : 408

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Book Description
This volume brings together the current literature on bacterial virulence and on cytokines to produce a synthesis that attempts to explain how infectious and commensal bacteria interact with man. An explanation is provided for this failure to respond to normal microflora.

Bacteria-cytokine Interactions in Health and Disease

Bacteria-cytokine Interactions in Health and Disease PDF Author: Brian Henderson
Publisher: Ashgate Publishing
ISBN:
Category : Medical
Languages : en
Pages : 408

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Book Description
This volume brings together the current literature on bacterial virulence and on cytokines to produce a synthesis that attempts to explain how infectious and commensal bacteria interact with man. An explanation is provided for this failure to respond to normal microflora.

Janeway's Immunobiology

Janeway's Immunobiology PDF Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :

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Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Cytokines and the Brain

Cytokines and the Brain PDF Author:
Publisher: Elsevier
ISBN: 0080559352
Category : Science
Languages : en
Pages : 609

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Book Description
This book opens a new page of neuro-immunobiology providing substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. The volume is a collection of complex, new data drawn from multiple areas of investigation in the field. The contents summarize current understanding on the presence and function of CNS cytokines and their receptors in a variety of CNS cells during health and disease. The chapters are a collection of complex, new data demonstrating the presence and synthesis of cytokines in brain cells, as well as their receptors on cell membranes in health and disease. The strength of the volume are the descriptions of the authors own investigations, together with those of others in the field pertaining to a large number of cytokines in brain function, as well as mechanisms involved in the development of CNS disorders, including multiple sclerosis and Alzheimer's disease. Also included are novel approaches to the treatment of CNS disorders based on new experimental data. The contributors to this volume are internationally known scientists and clinical researchers in their respective fields of investigation and treatment.*Opens a new page of neuro-immunobiology and provides substantive evidence for the promise of this field in the treatment of disease*Summarizes current understanding on the presence and function of central nervous system (CNS) cytokines and their receptors in a variety of CNS cells during health and disease*Includes novel approaches to the treatment of CNS disorders based on new experimental data*Offers new insight into triggers for the development of autoimmune diseases in the brain and the possibilities for treatment

Microbiomes of the Built Environment

Microbiomes of the Built Environment PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309449839
Category : Science
Languages : en
Pages : 318

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Book Description
People's desire to understand the environments in which they live is a natural one. People spend most of their time in spaces and structures designed, built, and managed by humans, and it is estimated that people in developed countries now spend 90 percent of their lives indoors. As people move from homes to workplaces, traveling in cars and on transit systems, microorganisms are continually with and around them. The human-associated microbes that are shed, along with the human behaviors that affect their transport and removal, make significant contributions to the diversity of the indoor microbiome. The characteristics of "healthy" indoor environments cannot yet be defined, nor do microbial, clinical, and building researchers yet understand how to modify features of indoor environmentsâ€"such as building ventilation systems and the chemistry of building materialsâ€"in ways that would have predictable impacts on microbial communities to promote health and prevent disease. The factors that affect the environments within buildings, the ways in which building characteristics influence the composition and function of indoor microbial communities, and the ways in which these microbial communities relate to human health and well-being are extraordinarily complex and can be explored only as a dynamic, interconnected ecosystem by engaging the fields of microbial biology and ecology, chemistry, building science, and human physiology. This report reviews what is known about the intersection of these disciplines, and how new tools may facilitate advances in understanding the ecosystem of built environments, indoor microbiomes, and effects on human health and well-being. It offers a research agenda to generate the information needed so that stakeholders with an interest in understanding the impacts of built environments will be able to make more informed decisions.

Bacterial Disease Mechanisms

Bacterial Disease Mechanisms PDF Author: Michael Wilson
Publisher: Cambridge University Press
ISBN: 9780521796897
Category : Medical
Languages : en
Pages : 698

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Book Description
Introductory textbook describing the ways in which bacteria cause disease at the molecular and cellular level.

Vascular Responses to Pathogens

Vascular Responses to Pathogens PDF Author: Felicity N.E. Gavins
Publisher: Academic Press
ISBN: 0128013257
Category : Medical
Languages : en
Pages : 254

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Book Description
Vascular Responses to Pathogens focuses on the growing research from leaders in the field for both the short and long-term impact of pathogens on the vasculature. It discusses various organisms, including bacteria, parasites, and viruses, and their role in key events leading to vascular disease. Formatted to discuss the topic of the interaction of pathogens with the vascular rather than individual diseases described separately, this reference demonstrates that common mechanisms are at play in many different diseases because they have a similar context, their vasculature. This all-inclusive reference book is a must-have tool for researchers and practicing clinicians in the areas of vascular biology, microvasculature, cardiology, and infectious disease. - Covers a wide spectrum of organisms and provides analysis of pathogens and current therapeutic strategies in the context of their vasculature - Provides detailed perspectives on key components contributing to vascular pathogens from leaders in the field - Interfaces between both vascular biology and microbiology by encompassing information on how pathogens affect both macro and microvasculature - Includes coverage of the clinical aspects of sepsis and current therapeutic strategies and anti-sepsis drugs

Immunology of Fungal Infections

Immunology of Fungal Infections PDF Author: Gordon D. Brown
Publisher: Springer Science & Business Media
ISBN: 1402054920
Category : Medical
Languages : en
Pages : 495

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Book Description
This text covers all aspects of the immunology of fungal infection. Beyond the basics, coverage includes recent developments in innate and adaptive immunological mechanisms involved in the host response to fungal infection. The volume’s topical sections provide an immunological perspective on the cells, soluble factors and receptors involved in recognising and combating fungal infections. Discussion includes descriptions of immunity to specific pathogens, immune-escape mechanisms used by fungi, and therapeutic strategies.

The Neutrophil

The Neutrophil PDF Author: Jon S. Abramson
Publisher: Oxford University Press, USA
ISBN:
Category : Art
Languages : en
Pages : 348

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Book Description
The third book in the group devoted to the "natural" immune system, this volume provides the ideal detailed, up-to-date overview of neutrophil function. Distilling new information alongside observations of the past, the book focuses on some of the most critical developments in currentneutrophil research. Specific examples of diseases resulting from neutrophil dysfunction and deficiency are brought to life by clinical case studies. An essential source of current research into this exciting field, this volume will be invaluable for advanced students and researchers in immunology,cell biology, and medicine.

Novel Cytokine Inhibitors

Novel Cytokine Inhibitors PDF Author: Gerry A. Higgs
Publisher: Springer
ISBN: 3034884508
Category : Medical
Languages : en
Pages : 284

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Book Description
Cytokines have become established as key mediators of the signs and symptoms of inflammatory diseases such as arthritis, dermatitis, asthma and multiple sclerosis. Furthermore, they are involved in the cascade of events leading to cardiovascular shock and are major regulators of the function of immune cells. This book reviews recent advances in the development of new anti-inflammatory drugs. It addresses different therapeutic intervention possibilities for new drugs, such as the cellular source of cytokines, specific receptors which induce cytokine synthesis, intracellular regulators of cytokine gene induction and expression, secretion and activation of cytokines, cytokine receptors and signalling pathways from these receptors. Accordingly, experts were drawn from different backgrounds including academic research institutes, the pharmaceutical industry and clinical pharmacology. In each area, the opportunities for drug development are highlighted and, where possible, clinical data is reviewed.

Polymicrobial Diseases

Polymicrobial Diseases PDF Author: Kim A. Brogden
Publisher:
ISBN:
Category : Bacteria
Languages : en
Pages : 460

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Book Description
Polymicrobial diseases, those involving more than one etiologic agent, are more common than is generally realized and include respiratory diseases, gastroenteritis, conjunctivitis, keratitis, hepatitis, periodontal diseases, multiple sclerosis, genital infections, intra -- abdominal infections, and pertussis.