The Cheating Cell

The Cheating Cell PDF Author: Athena Aktipis
Publisher: Princeton University Press
ISBN: 0691163847
Category : Medical
Languages : en
Pages : 256

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Book Description
A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked because the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments. Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of control, giving rise to cancer. Aktipis illustrates how evolution has paved the way for cancer’s ubiquity, and why it will exist as long as multicellular life does. Even so, she argues, this doesn’t mean we should give up on treating cancer—in fact, evolutionary approaches offer new and promising options for the disease’s prevention and treatments that aim at long-term management rather than simple eradication. Looking across species—from sponges and cacti to dogs and elephants—we are discovering new mechanisms of tumor suppression and the many ways that multicellular life-forms have evolved to keep cancer under control. By accepting that cancer is a part of our biological past, present, and future—and that we cannot win a war against evolution—treatments can become smarter, more strategic, and more humane. Unifying the latest research from biology, ecology, medicine, and social science, The Cheating Cell challenges us to rethink cancer’s fundamental nature and our relationship to it.

The Cheating Cell

The Cheating Cell PDF Author: Athena Aktipis
Publisher: Princeton University Press
ISBN: 0691163847
Category : Medical
Languages : en
Pages : 256

Get Book Here

Book Description
A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked because the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments. Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of control, giving rise to cancer. Aktipis illustrates how evolution has paved the way for cancer’s ubiquity, and why it will exist as long as multicellular life does. Even so, she argues, this doesn’t mean we should give up on treating cancer—in fact, evolutionary approaches offer new and promising options for the disease’s prevention and treatments that aim at long-term management rather than simple eradication. Looking across species—from sponges and cacti to dogs and elephants—we are discovering new mechanisms of tumor suppression and the many ways that multicellular life-forms have evolved to keep cancer under control. By accepting that cancer is a part of our biological past, present, and future—and that we cannot win a war against evolution—treatments can become smarter, more strategic, and more humane. Unifying the latest research from biology, ecology, medicine, and social science, The Cheating Cell challenges us to rethink cancer’s fundamental nature and our relationship to it.

The Soul of an Octopus

The Soul of an Octopus PDF Author: Sy Montgomery
Publisher: Simon and Schuster
ISBN: 1501161148
Category : Nature
Languages : en
Pages : 272

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Book Description
Finalist for the National Book Award for Nonfiction * New York Times Bestseller * A Huffington Post Notable Nonfiction Book of the Year * One of the Best Books of the Month on Goodreads * Library Journal Best Sci-Tech Book of the Year * An American Library Association Notable Book of the Year “Sy Montgomery’s The Soul of an Octopus does for the creature what Helen Macdonald’s H Is for Hawk did for raptors.” —New Statesman, UK “One of the best science books of the year.” —Science Friday, NPR Another New York Times bestseller from the author of The Good Good Pig, this “fascinating…touching…informative…entertaining” (The Daily Beast) book explores the emotional and physical world of the octopus—a surprisingly complex, intelligent, and spirited creature—and the remarkable connections it makes with humans. In pursuit of the wild, solitary, predatory octopus, popular naturalist Sy Montgomery has practiced true immersion journalism. From New England aquarium tanks to the reefs of French Polynesia and the Gulf of Mexico, she has befriended octopuses with strikingly different personalities—gentle Athena, assertive Octavia, curious Kali, and joyful Karma. Each creature shows her cleverness in myriad ways: escaping enclosures like an orangutan; jetting water to bounce balls; and endlessly tricking companions with multiple “sleights of hand” to get food. Scientists have only recently accepted the intelligence of dogs, birds, and chimpanzees but now are watching octopuses solve problems and are trying to decipher the meaning of the animal’s color-changing techniques. With her “joyful passion for these intelligent and fascinating creatures” (Library Journal Editors’ Spring Pick), Montgomery chronicles the growing appreciation of this mollusk as she tells a unique love story. By turns funny, entertaining, touching, and profound, The Soul of an Octopus reveals what octopuses can teach us about the meeting of two very different minds.

Athena the Proud

Athena the Proud PDF Author: Joan Holub
Publisher: Simon and Schuster
ISBN: 1442488220
Category : Juvenile Fiction
Languages : en
Pages : 108

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Book Description
Athena wants to upgrade a labyrinth for King Minos, but her approach causes problems in this Goddess Girls adventure. Athena’s arrogance gets the best of her when her attempts to improve King Minos’s labyrinth have unexpected—and disastrous—results!

Athena Always Knows Best

Athena Always Knows Best PDF Author: Athena Publishing
Publisher:
ISBN:
Category :
Languages : en
Pages : 120

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Book Description
This 120-page Athena Journal features: 120 wide-ruled lined pages 6 x 9 inches in size - big enough for your daily writings and also small enough to take with you smooth white-color paper, perfect for ink, gel pens, pencils or even colored pencils a black matte-finish cover for an elegant, professional look and feel This (Athena Always Knows Best) journal can be used for writing poetry, jotting down your brilliant ideas, recording your accomplishments and much more. Use it as a diary or gratitude journal, a travel journal or to record your food intake or progress toward your fitness and life goals. The simple lined pages allow you to use it however you wish. Our journals to write in offer a wide variety of journals, so keep one by your bedside as a dream journal, one in your car to record mileage and expenses, one by your computer for login names and passwords, and one in your purse or backpack to jot down random thoughts and inspirations throughout the day. Paper journals never need to be charged and of course no batteries are required! You only need your thoughts and dreams and something to write with. This Athena journal makes a wonderful present, so put a smile on someone's face today!

The Director's Cut

The Director's Cut PDF Author: Janice Thompson
Publisher: Baker Books
ISBN: 0800733479
Category : Fiction
Languages : en
Pages : 304

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Book Description
Sitcom director Tia Morales is used to calling the shots and having everything securely in her control--that is, until a handsome cameraman turns both her heart and her life upside-down.

Journey Unknown

Journey Unknown PDF Author: Travis G. Campbell
Publisher: FriesenPress
ISBN: 1525541102
Category : Fiction
Languages : en
Pages : 227

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Book Description
On the beautiful island of Mykonos, in the days of Ancient Greece, Teraditus, now an old man, lives a life of peace and simplicity. However, great mystery lies behind his eyes, with untold stories and thrilling adventures. As his family members gather for a reunion, a curious daughter-in-law begins to dig into Teraditus’s past, prompted by the appearance of an enigmatic woman—an old friend of Teraditus’s—who seems to emanate a power beyond this world. Little does everybody know that Teraditus’s own gathering mirrors one happening within the Council of the Gods, and that the beings involved—humans, gods, and those in-between—are all divinely linked. When Teraditus is convinced to share his story, he begins in his home land of Libu (modern-day Libya), where, as a ten-year-old boy, he lived a life of relative tranquility, spending his days fishing with his father and their odd crew, learning survival skills from his big-brother figure, and going on nighttime expeditions with his cousin, Gershom. When one of these expeditions leads them into the claws of faceless men—a darkness the children could never have fathomed—everything Teraditus knows and loves is ripped from his grasp in a single night. When he awakens from this nightmare, pulled back from the brink of death by soldiers in bronze armors and crimson cloaks, he finds himself bound for a future overseas in the Greek city-state of Sparta, where he will become either a soldier or a slave. Having lost everything, his fate now lies in the hands of the gods. Journey Unknown, the first volume in Travis Campbell’s compelling The Children of Sparta series, is a historical fantasy where readers will embark on a journey that spans from the realms of the gods down to the bloody reality of life as a lost child in a world without a place to call home. With tragedies, victories, and struggles around every corner, readers will not only get a fascinating glimpse into what life was like in the ancient days before the Battle of Thermopylae, but they will be endlessly curious to know of the great destiny—which has come at a great cost—that awaits the young protagonist and his cousin.

The Eleventh Trade

The Eleventh Trade PDF Author: Alyssa Hollingsworth
Publisher: Roaring Brook Press
ISBN: 1250155770
Category : Juvenile Fiction
Languages : en
Pages : 288

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Book Description
From debut author Alyssa Hollingsworth comes a story about living with fear, being a friend, and finding a new place to call home. They say you can't get something for nothing, but nothing is all Sami has. When his grandfather’s most-prized possession—a traditional Afghan instrument called a rebab—is stolen, Sami resolves to get it back. He finds it at a music store, but it costs $700, and Sami doesn’t have even one penny. What he does have is a keychain that has caught the eye of his classmate. If he trades the keychain for something more valuable, could he keep trading until he has $700? Sami is about to find out. The Eleventh Trade is both a classic middle school story and a story about being a refugee. Alyssa Hollingsworth tackles a big issue with a light touch. 2020 UKLA Award Winner

Athena the Wise

Athena the Wise PDF Author: Joan Holub
Publisher: Simon and Schuster
ISBN: 1442420987
Category : Juvenile Fiction
Languages : en
Pages : 260

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Book Description
These classic myths from the Greek pantheon are given a modern twist that contemporary tweens can relate to, from dealing with bullies like Medusa to a first crush on an unlikely boy. Goddess Girls follows four goddesses-in-training – Athena, Persephone, Aphrodite, and Artemis – as they navigate the ins and outs of divine social life at Mount Olympus Academy, where the most priviledged gods and goddesses of the Greek pantheon hone their mythical skills. In book 5, Principal Zeus asks Athena to help Heracles (aka Hercules in the Roman pantheon) complete his twelve labors. But when Heracles starts borrowing Athena's friends things without asking, will she be able to help him set things straight?

Serverless Analytics with Amazon Athena

Serverless Analytics with Amazon Athena PDF Author: Anthony Virtuoso
Publisher: Packt Publishing Ltd
ISBN: 1800567863
Category : Computers
Languages : en
Pages : 438

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Book Description
Get more from your data with Amazon Athena's ease-of-use, interactive performance, and pay-per-query pricing Key FeaturesExplore the promising capabilities of Amazon Athena and Athena's Query Federation SDKUse Athena to prepare data for common machine learning activitiesCover best practices for setting up connectivity between your application and Athena and security considerationsBook Description Amazon Athena is an interactive query service that makes it easy to analyze data in Amazon S3 using SQL, without needing to manage any infrastructure. This book begins with an overview of the serverless analytics experience offered by Athena and teaches you how to build and tune an S3 Data Lake using Athena, including how to structure your tables using open-source file formats like Parquet. You'll learn how to build, secure, and connect to a data lake with Athena and Lake Formation. Next, you'll cover key tasks such as ad hoc data analysis, working with ETL pipelines, monitoring and alerting KPI breaches using CloudWatch Metrics, running customizable connectors with AWS Lambda, and more. Moving on, you'll work through easy integrations, troubleshooting and tuning common Athena issues, and the most common reasons for query failure. You will also review tips to help diagnose and correct failing queries in your pursuit of operational excellence. Finally, you'll explore advanced concepts such as Athena Query Federation and Athena ML to generate powerful insights without needing to touch a single server. By the end of this book, you'll be able to build and use a data lake with Amazon Athena to add data-driven features to your app and perform the kind of ad hoc data analysis that often precedes many of today's ML modeling exercises. What you will learnSecure and manage the cost of querying your dataUse Athena ML and User Defined Functions (UDFs) to add advanced features to your reportsWrite your own Athena Connector to integrate with a custom data sourceDiscover your datasets on S3 using AWS Glue CrawlersIntegrate Amazon Athena into your applicationsSetup Identity and Access Management (IAM) policies to limit access to tables and databases in Glue Data CatalogAdd an Amazon SageMaker Notebook to your Athena queriesGet to grips with using Athena for ETL pipelinesWho this book is for Business intelligence (BI) analysts, application developers, and system administrators who are looking to generate insights from an ever-growing sea of data while controlling costs and limiting operational burden, will find this book helpful. Basic SQL knowledge is expected to make the most out of this book.

Ancient Greek Religion

Ancient Greek Religion PDF Author: Emily Kearns
Publisher: John Wiley & Sons
ISBN: 1405149280
Category : Religion
Languages : en
Pages : 386

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Book Description
Ancient Greek Religion: Historical Sources in Translation presents a wide range of documents relating to the religious world of the ancient Greeks from the earliest surviving literature to around the end of the fourth century BCE. Presents a wide range of documents relating to the religious world of the ancient Greeks, from the earliest surviving literature to around the end of the fourth century BCE Provides extensive background information for readers with no previous knowledge of classical studies Brings together new and rare passages for comparison – with occasional new interpretations – to appeal to professionals Offers a variety of less frequently examined material and looks at familiar texts in new ways Includes the use of extensive cross-referencing to indicate the interconnectedness of different aspects of religious practice and thought Includes the most comprehensive commentary and updated passages available in a single volume