Author: Leon Shargel
Publisher: McGraw-Hill/Appleton & Lange
ISBN: 9780838502396
Category : Biopharmaceutics
Languages : en
Pages : 625
Book Description
Applied Biopharmaceutics and Pharmacokinetics
Author: Leon Shargel
Publisher: McGraw-Hill/Appleton & Lange
ISBN: 9780838502396
Category : Biopharmaceutics
Languages : en
Pages : 625
Book Description
Publisher: McGraw-Hill/Appleton & Lange
ISBN: 9780838502396
Category : Biopharmaceutics
Languages : en
Pages : 625
Book Description
Vander's Renal Physiology, 7th Edition
Author: Douglas C. Eaton
Publisher: McGraw Hill Professional
ISBN: 0071613048
Category : Medical
Languages : en
Pages : 231
Book Description
The structure, function, and pathologies of the human kidney -- simplified and explained A Doody's Core Title for 2011! 4 STAR DOODY'S REVIEW! "This seventh edition of a concise, well written book on renal physiology continues the legacy of the book as a major contributor in the field....This well written book is an excellent review of renal function and is one of the best concise reviews of the topic."--Doody's Review Service Written in a concise, conversational style, this trusted text reviews the fundamental principles of renal physiology that are essential for an understanding of clinical medicine. Combining the latest research with a fully integrated teaching approach, Vander's Renal Physiology explains how the kidneys affect other body systems and how they in turn are affected by these systems. Filled with the learning tools you need to truly learn key concepts rather than merely memorize facts, Vander's will prove valuable to you at every stage of your studies or practice. Features: New Global case studies New An online physiology learning center that offers additional exam questions, artwork, and graphs Offers the best review of renal physiology available for the USMLE Step 1 Begins with the basics and works up to advanced principles Distills the essence of renal processes and their regulation in a concise, integrated manner that focuses on the logic of renal processes Features learning aids such as flow charts, diagrams, key concepts, clinical examples, learning objectives, and review questions with answers and explanations Explains the relationship between blood pressure and renal function Presents the normal functions of the kidney with clinical correlations to disease states Includes the most current research on the molecular and genetic principles underlying renal physiology
Publisher: McGraw Hill Professional
ISBN: 0071613048
Category : Medical
Languages : en
Pages : 231
Book Description
The structure, function, and pathologies of the human kidney -- simplified and explained A Doody's Core Title for 2011! 4 STAR DOODY'S REVIEW! "This seventh edition of a concise, well written book on renal physiology continues the legacy of the book as a major contributor in the field....This well written book is an excellent review of renal function and is one of the best concise reviews of the topic."--Doody's Review Service Written in a concise, conversational style, this trusted text reviews the fundamental principles of renal physiology that are essential for an understanding of clinical medicine. Combining the latest research with a fully integrated teaching approach, Vander's Renal Physiology explains how the kidneys affect other body systems and how they in turn are affected by these systems. Filled with the learning tools you need to truly learn key concepts rather than merely memorize facts, Vander's will prove valuable to you at every stage of your studies or practice. Features: New Global case studies New An online physiology learning center that offers additional exam questions, artwork, and graphs Offers the best review of renal physiology available for the USMLE Step 1 Begins with the basics and works up to advanced principles Distills the essence of renal processes and their regulation in a concise, integrated manner that focuses on the logic of renal processes Features learning aids such as flow charts, diagrams, key concepts, clinical examples, learning objectives, and review questions with answers and explanations Explains the relationship between blood pressure and renal function Presents the normal functions of the kidney with clinical correlations to disease states Includes the most current research on the molecular and genetic principles underlying renal physiology
Continuous Renal Replacement Therapy
Author: John A. Kellum
Publisher: Oxford University Press
ISBN: 019022553X
Category : Medical
Languages : en
Pages : 329
Book Description
Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.
Publisher: Oxford University Press
ISBN: 019022553X
Category : Medical
Languages : en
Pages : 329
Book Description
Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.
Application of the Concept of Exemption
Author: IAEA
Publisher: International Atomic Energy Agency
ISBN: 920132023X
Category : Technology & Engineering
Languages : en
Pages : 145
Book Description
Intended for use by government officials, and those working for regulatory bodies and operating organizations, this publication will assist in the application of IAEA Safety Standards Series No. GSR Part 3 in relation to the concept of exemption of practices or sources within practices from regulatory control. It addresses the application of a graded approach to the concept of exemption through the use of generic exemption and specific exemption. It explains the concept of exclusion and its relationship to exemption and clearance. The recommendations provided in this publication are applicable to all facilities and activities that use, manufacture, process, trade or store radioactive sources or material containing either natural or artificial radionuclides. The Safety Guide primarily addresses exemption from regulatory control in planned exposure situations. Although, the concept of exemption is only applicable to planned exposure situations, guidance on the application of a screening approach for decision making in managing certain existing exposure situations is also provided.
Publisher: International Atomic Energy Agency
ISBN: 920132023X
Category : Technology & Engineering
Languages : en
Pages : 145
Book Description
Intended for use by government officials, and those working for regulatory bodies and operating organizations, this publication will assist in the application of IAEA Safety Standards Series No. GSR Part 3 in relation to the concept of exemption of practices or sources within practices from regulatory control. It addresses the application of a graded approach to the concept of exemption through the use of generic exemption and specific exemption. It explains the concept of exclusion and its relationship to exemption and clearance. The recommendations provided in this publication are applicable to all facilities and activities that use, manufacture, process, trade or store radioactive sources or material containing either natural or artificial radionuclides. The Safety Guide primarily addresses exemption from regulatory control in planned exposure situations. Although, the concept of exemption is only applicable to planned exposure situations, guidance on the application of a screening approach for decision making in managing certain existing exposure situations is also provided.
Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Third Edition
Author: Johan Gabrielsson
Publisher: CRC Press
ISBN: 9789186274924
Category : Medical
Languages : en
Pages : 926
Book Description
This is a revised and very expanded version of the previous second edition of the book. "Pharmacokinetic and Pharmacodynamic Data Analysis" provides an introduction into pharmacokinetic and pharmacodynamic concepts using simple illustrations and reasoning. It describes ways in which pharmacodynamic and pharmacodynamic theory may be used to give insight into modeling questions and how these questions can in turn lead to new knowledge. This book differentiates itself from other texts in this area in that it bridges the gap between relevant theory and the actual application of the theory to real life situations. The book is divided into two parts; the first introduces fundamental principles of PK and PD concepts, and principles of mathematical modeling, while the second provides case studies obtained from drug industry and academia. Topics included in the first part include a discussion of the statistical principles of model fitting, including how to assess the adequacy of the fit of a model, as well as strategies for selection of time points to be included in the design of a study. The first part also introduces basic pharmacokinetic and pharmacodynamic concepts, including an excellent discussion of effect compartment (link) models as well as indirect response models. The second part of the text includes over 70 modeling case studies. These include a discussion of the selection of the model, derivation of initial parameter estimates and interpretation of the corresponding output. Finally, the authors discuss a number of pharmacodynamic modeling situations including receptor binding models, synergy, and tolerance models (feedback and precursor models). This book will be of interest to researchers, to graduate students and advanced undergraduate students in the PK/PD area who wish to learn how to analyze biological data and build models and to become familiar with new areas of application. In addition, the text will be of interest to toxicologists interested in learning about determinants of exposure and performing toxicokinetic modeling. The inclusion of the numerous exercises and models makes it an excellent primary or adjutant text for traditional PK courses taught in pharmacy and medical schools. A diskette is included with the text that includes all of the exercises and solutions using WinNonlin.
Publisher: CRC Press
ISBN: 9789186274924
Category : Medical
Languages : en
Pages : 926
Book Description
This is a revised and very expanded version of the previous second edition of the book. "Pharmacokinetic and Pharmacodynamic Data Analysis" provides an introduction into pharmacokinetic and pharmacodynamic concepts using simple illustrations and reasoning. It describes ways in which pharmacodynamic and pharmacodynamic theory may be used to give insight into modeling questions and how these questions can in turn lead to new knowledge. This book differentiates itself from other texts in this area in that it bridges the gap between relevant theory and the actual application of the theory to real life situations. The book is divided into two parts; the first introduces fundamental principles of PK and PD concepts, and principles of mathematical modeling, while the second provides case studies obtained from drug industry and academia. Topics included in the first part include a discussion of the statistical principles of model fitting, including how to assess the adequacy of the fit of a model, as well as strategies for selection of time points to be included in the design of a study. The first part also introduces basic pharmacokinetic and pharmacodynamic concepts, including an excellent discussion of effect compartment (link) models as well as indirect response models. The second part of the text includes over 70 modeling case studies. These include a discussion of the selection of the model, derivation of initial parameter estimates and interpretation of the corresponding output. Finally, the authors discuss a number of pharmacodynamic modeling situations including receptor binding models, synergy, and tolerance models (feedback and precursor models). This book will be of interest to researchers, to graduate students and advanced undergraduate students in the PK/PD area who wish to learn how to analyze biological data and build models and to become familiar with new areas of application. In addition, the text will be of interest to toxicologists interested in learning about determinants of exposure and performing toxicokinetic modeling. The inclusion of the numerous exercises and models makes it an excellent primary or adjutant text for traditional PK courses taught in pharmacy and medical schools. A diskette is included with the text that includes all of the exercises and solutions using WinNonlin.
Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications
Author: Hartmut Derendorf
Publisher: Lippincott Williams & Wilkins
ISBN: 1496385896
Category : Medical
Languages : en
Pages : 1334
Book Description
Updated with the latest clinical advances, Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition , explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.
Publisher: Lippincott Williams & Wilkins
ISBN: 1496385896
Category : Medical
Languages : en
Pages : 1334
Book Description
Updated with the latest clinical advances, Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition , explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.
Renal Physiology
Author: Carl W Gottschalk
Publisher: Springer
ISBN: 1461475457
Category : Medical
Languages : en
Pages : 515
Book Description
Each chapter in this authoritative volume is written by a well-known physiologist who has contributed to our current understanding of renal function. Together the authors offer a unique, inside perspective on the historical record of the discipline, from its roots in the ancient world to the most recent findings of modern times. Among the many topics discussed are renal blood flow and the dynamics of glomerular filtration; the clearance concept in renal physiology; micropuncture and microperfusion; transport of electrolytes across renal tubules; and diuretics and renal drug development.
Publisher: Springer
ISBN: 1461475457
Category : Medical
Languages : en
Pages : 515
Book Description
Each chapter in this authoritative volume is written by a well-known physiologist who has contributed to our current understanding of renal function. Together the authors offer a unique, inside perspective on the historical record of the discipline, from its roots in the ancient world to the most recent findings of modern times. Among the many topics discussed are renal blood flow and the dynamics of glomerular filtration; the clearance concept in renal physiology; micropuncture and microperfusion; transport of electrolytes across renal tubules; and diuretics and renal drug development.
Medical Management of Radiation Injuries
Author: IAEA
Publisher: International Atomic Energy Agency
ISBN: 9201066228
Category : Medical
Languages : en
Pages : 108
Book Description
This publication focuses on the medical management of individuals involved in radiation emergencies, especially those who have been exposed to high doses of ionizing radiation. Its primary objective is to provide practical information, to be used for treatment decisions by medical personnel during a radiation emergency. It also addresses general and specific measures for the medical management of individuals who have been internally contaminated with radionuclides. This publication is complementary to other publications developed by the IAEA in the medical area of radiation emergencies.
Publisher: International Atomic Energy Agency
ISBN: 9201066228
Category : Medical
Languages : en
Pages : 108
Book Description
This publication focuses on the medical management of individuals involved in radiation emergencies, especially those who have been exposed to high doses of ionizing radiation. Its primary objective is to provide practical information, to be used for treatment decisions by medical personnel during a radiation emergency. It also addresses general and specific measures for the medical management of individuals who have been internally contaminated with radionuclides. This publication is complementary to other publications developed by the IAEA in the medical area of radiation emergencies.
Human Dimension and Interior Space
Author: Julius Panero
Publisher: Watson-Guptill
ISBN: 0770434606
Category : Architecture
Languages : en
Pages : 322
Book Description
The study of human body measurements on a comparative basis is known as anthropometrics. Its applicability to the design process is seen in the physical fit, or interface, between the human body and the various components of interior space. Human Dimension and Interior Space is the first major anthropometrically based reference book of design standards for use by all those involved with the physical planning and detailing of interiors, including interior designers, architects, furniture designers, builders, industrial designers, and students of design. The use of anthropometric data, although no substitute for good design or sound professional judgment should be viewed as one of the many tools required in the design process. This comprehensive overview of anthropometrics consists of three parts. The first part deals with the theory and application of anthropometrics and includes a special section dealing with physically disabled and elderly people. It provides the designer with the fundamentals of anthropometrics and a basic understanding of how interior design standards are established. The second part contains easy-to-read, illustrated anthropometric tables, which provide the most current data available on human body size, organized by age and percentile groupings. Also included is data relative to the range of joint motion and body sizes of children. The third part contains hundreds of dimensioned drawings, illustrating in plan and section the proper anthropometrically based relationship between user and space. The types of spaces range from residential and commercial to recreational and institutional, and all dimensions include metric conversions. In the Epilogue, the authors challenge the interior design profession, the building industry, and the furniture manufacturer to seriously explore the problem of adjustability in design. They expose the fallacy of designing to accommodate the so-called average man, who, in fact, does not exist. Using government data, including studies prepared by Dr. Howard Stoudt, Dr. Albert Damon, and Dr. Ross McFarland, formerly of the Harvard School of Public Health, and Jean Roberts of the U.S. Public Health Service, Panero and Zelnik have devised a system of interior design reference standards, easily understood through a series of charts and situation drawings. With Human Dimension and Interior Space, these standards are now accessible to all designers of interior environments.
Publisher: Watson-Guptill
ISBN: 0770434606
Category : Architecture
Languages : en
Pages : 322
Book Description
The study of human body measurements on a comparative basis is known as anthropometrics. Its applicability to the design process is seen in the physical fit, or interface, between the human body and the various components of interior space. Human Dimension and Interior Space is the first major anthropometrically based reference book of design standards for use by all those involved with the physical planning and detailing of interiors, including interior designers, architects, furniture designers, builders, industrial designers, and students of design. The use of anthropometric data, although no substitute for good design or sound professional judgment should be viewed as one of the many tools required in the design process. This comprehensive overview of anthropometrics consists of three parts. The first part deals with the theory and application of anthropometrics and includes a special section dealing with physically disabled and elderly people. It provides the designer with the fundamentals of anthropometrics and a basic understanding of how interior design standards are established. The second part contains easy-to-read, illustrated anthropometric tables, which provide the most current data available on human body size, organized by age and percentile groupings. Also included is data relative to the range of joint motion and body sizes of children. The third part contains hundreds of dimensioned drawings, illustrating in plan and section the proper anthropometrically based relationship between user and space. The types of spaces range from residential and commercial to recreational and institutional, and all dimensions include metric conversions. In the Epilogue, the authors challenge the interior design profession, the building industry, and the furniture manufacturer to seriously explore the problem of adjustability in design. They expose the fallacy of designing to accommodate the so-called average man, who, in fact, does not exist. Using government data, including studies prepared by Dr. Howard Stoudt, Dr. Albert Damon, and Dr. Ross McFarland, formerly of the Harvard School of Public Health, and Jean Roberts of the U.S. Public Health Service, Panero and Zelnik have devised a system of interior design reference standards, easily understood through a series of charts and situation drawings. With Human Dimension and Interior Space, these standards are now accessible to all designers of interior environments.
Occupational Radiation Protection in the Uranium Mining and Processing Industry
Author: International Atomic Energy Agency
Publisher:
ISBN: 9789201069191
Category :
Languages : en
Pages : 217
Book Description
This Safety Report has been developed as part of the IAEA programme on occupational radiation protection to provide for the application of its safety standards in implementing a graded approach to the protection of workers against exposures associated with uranium mining and processing. The publication describes the methods of production associated with the uranium industry and provides practical information on the radiological risks to workers in the exploration, mining and processing of uranium. It is a compilation of detailed information on uranium mining and processing stages and techniques, general radiation protection considerations in the relevant industry, general methodology applicable for control, monitoring and dose assessment, exposure pathways, and radiation protection programs for the range of commonly used mining and processing techniques.
Publisher:
ISBN: 9789201069191
Category :
Languages : en
Pages : 217
Book Description
This Safety Report has been developed as part of the IAEA programme on occupational radiation protection to provide for the application of its safety standards in implementing a graded approach to the protection of workers against exposures associated with uranium mining and processing. The publication describes the methods of production associated with the uranium industry and provides practical information on the radiological risks to workers in the exploration, mining and processing of uranium. It is a compilation of detailed information on uranium mining and processing stages and techniques, general radiation protection considerations in the relevant industry, general methodology applicable for control, monitoring and dose assessment, exposure pathways, and radiation protection programs for the range of commonly used mining and processing techniques.