Author: S.C. Maheshwari
Publisher: Avichal Publishing Company
ISBN: 817739374X
Category :
Languages : en
Pages : 144
Book Description
The early schooling years in a child’s life are of extreme importance. These are the times when he focuses his eyes and mind on everything that is new and appealing. His mind is untrained and he has learned only the basics of communication. His vocabulary is limited but he is eager to learn.Whatever is presented to him, he absorbs like a sponge. His attention span is short and he requires constant reinforcement. What interests him most is things and events around him. This is the golden opportunity to inculcate in him a spirit of adventure and inquiry, to teach him to ask, to reason and to pick up healthy habits. With this in mind our publisher decided to bring out a science series for the junior classes.
APC New Discovery - Class 4
Author: S.C. Maheshwari
Publisher: Avichal Publishing Company
ISBN: 817739374X
Category :
Languages : en
Pages : 144
Book Description
The early schooling years in a child’s life are of extreme importance. These are the times when he focuses his eyes and mind on everything that is new and appealing. His mind is untrained and he has learned only the basics of communication. His vocabulary is limited but he is eager to learn.Whatever is presented to him, he absorbs like a sponge. His attention span is short and he requires constant reinforcement. What interests him most is things and events around him. This is the golden opportunity to inculcate in him a spirit of adventure and inquiry, to teach him to ask, to reason and to pick up healthy habits. With this in mind our publisher decided to bring out a science series for the junior classes.
Publisher: Avichal Publishing Company
ISBN: 817739374X
Category :
Languages : en
Pages : 144
Book Description
The early schooling years in a child’s life are of extreme importance. These are the times when he focuses his eyes and mind on everything that is new and appealing. His mind is untrained and he has learned only the basics of communication. His vocabulary is limited but he is eager to learn.Whatever is presented to him, he absorbs like a sponge. His attention span is short and he requires constant reinforcement. What interests him most is things and events around him. This is the golden opportunity to inculcate in him a spirit of adventure and inquiry, to teach him to ask, to reason and to pick up healthy habits. With this in mind our publisher decided to bring out a science series for the junior classes.
APC New Discovery - Class 2
Author: S.C. Maheshwari
Publisher: Avichal Publishing Company
ISBN: 8177394215
Category :
Languages : en
Pages : 120
Book Description
The early schooling years in a child’s life are of extreme importance. These are the times when he focuses his eyes and mind on everything that is new and appealing. His mind is untrained and he has learned only the basics of communication. His vocabulary is limited but he is eager to learn.Whatever is presented to him, he absorbs like a sponge. His attention span is short and he requires constant reinforcement. What interests him most is things and events around him. This is the golden opportunity to inculcate in him a spirit of adventure and inquiry, to teach him to ask, to reason and to pick up healthy habits. With this in mind our publisher decided to bring out a science series for the junior classes.
Publisher: Avichal Publishing Company
ISBN: 8177394215
Category :
Languages : en
Pages : 120
Book Description
The early schooling years in a child’s life are of extreme importance. These are the times when he focuses his eyes and mind on everything that is new and appealing. His mind is untrained and he has learned only the basics of communication. His vocabulary is limited but he is eager to learn.Whatever is presented to him, he absorbs like a sponge. His attention span is short and he requires constant reinforcement. What interests him most is things and events around him. This is the golden opportunity to inculcate in him a spirit of adventure and inquiry, to teach him to ask, to reason and to pick up healthy habits. With this in mind our publisher decided to bring out a science series for the junior classes.
Visual Knowledge Discovery and Machine Learning
Author: Boris Kovalerchuk
Publisher: Springer
ISBN: 3319730401
Category : Technology & Engineering
Languages : en
Pages : 332
Book Description
This book combines the advantages of high-dimensional data visualization and machine learning in the context of identifying complex n-D data patterns. It vastly expands the class of reversible lossless 2-D and 3-D visualization methods, which preserve the n-D information. This class of visual representations, called the General Lines Coordinates (GLCs), is accompanied by a set of algorithms for n-D data classification, clustering, dimension reduction, and Pareto optimization. The mathematical and theoretical analyses and methodology of GLC are included, and the usefulness of this new approach is demonstrated in multiple case studies. These include the Challenger disaster, world hunger data, health monitoring, image processing, text classification, market forecasts for a currency exchange rate, computer-aided medical diagnostics, and others. As such, the book offers a unique resource for students, researchers, and practitioners in the emerging field of Data Science.
Publisher: Springer
ISBN: 3319730401
Category : Technology & Engineering
Languages : en
Pages : 332
Book Description
This book combines the advantages of high-dimensional data visualization and machine learning in the context of identifying complex n-D data patterns. It vastly expands the class of reversible lossless 2-D and 3-D visualization methods, which preserve the n-D information. This class of visual representations, called the General Lines Coordinates (GLCs), is accompanied by a set of algorithms for n-D data classification, clustering, dimension reduction, and Pareto optimization. The mathematical and theoretical analyses and methodology of GLC are included, and the usefulness of this new approach is demonstrated in multiple case studies. These include the Challenger disaster, world hunger data, health monitoring, image processing, text classification, market forecasts for a currency exchange rate, computer-aided medical diagnostics, and others. As such, the book offers a unique resource for students, researchers, and practitioners in the emerging field of Data Science.
APC New Discovery - Class 5
Author: S.C. Maheshwari
Publisher: Avichal Publishing Company
ISBN: 8177393758
Category :
Languages : en
Pages : 152
Book Description
The early schooling years in a child’s life are of extreme importance. These are the times when he focuses his eyes and mind on everything that is new and appealing. His mind is untrained and he has learned only the basics of communication. His vocabulary is limited but he is eager to learn.Whatever is presented to him, he absorbs like a sponge. His attention span is short and he requires constant reinforcement. What interests him most is things and events around him. This is the golden opportunity to inculcate in him a spirit of adventure and inquiry, to teach him to ask, to reason and to pick up healthy habits. With this in mind our publisher decided to bring out a science series for the junior classes.
Publisher: Avichal Publishing Company
ISBN: 8177393758
Category :
Languages : en
Pages : 152
Book Description
The early schooling years in a child’s life are of extreme importance. These are the times when he focuses his eyes and mind on everything that is new and appealing. His mind is untrained and he has learned only the basics of communication. His vocabulary is limited but he is eager to learn.Whatever is presented to him, he absorbs like a sponge. His attention span is short and he requires constant reinforcement. What interests him most is things and events around him. This is the golden opportunity to inculcate in him a spirit of adventure and inquiry, to teach him to ask, to reason and to pick up healthy habits. With this in mind our publisher decided to bring out a science series for the junior classes.
Clinical Immunology,Principles and Practice (Expert Consult - Online and Print),4
Author: Thomas A. Fleisher
Publisher: Elsevier Health Sciences
ISBN: 0723436916
Category : Medical
Languages : en
Pages : 1325
Book Description
Written and edited by international leaders in the field, this book has, through two best-selling editions, been the place to turn for authoritative answers to your toughest challenges in clinical immunology. Now in full color and one single volume, the 3rd Edition brings you the very latest immunology knowledge - so you can offer your patients the best possible care. The user-friendly book and the fully searchable companion web site give you two ways to find the answers you need quickly...and regular online updates keep you absolutely current. Leading international experts equip you with peerless advice and global best practices to enhance your diagnosis and management of a full range of immunologic problems. A highly clinical focus and an extremely practical organization expedite access to the answers you need in your daily practice. Cutting-edge coverage of the human genome project, immune-modifier drugs, and many other vital updates keeps you at the forefront of your field. A new organization places scientific and clinical material side by side, to simplify your research and highlight the clinical relevance of the topics covered. A multimedia format allows you to find information conveniently, both inside the exceptionally user-friendly book and at the fully searchable companion web site. Regular updates online ensure that you'll always have the latest knowledge at your fingertips. Includes many new and improved illustrations and four color design. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.
Publisher: Elsevier Health Sciences
ISBN: 0723436916
Category : Medical
Languages : en
Pages : 1325
Book Description
Written and edited by international leaders in the field, this book has, through two best-selling editions, been the place to turn for authoritative answers to your toughest challenges in clinical immunology. Now in full color and one single volume, the 3rd Edition brings you the very latest immunology knowledge - so you can offer your patients the best possible care. The user-friendly book and the fully searchable companion web site give you two ways to find the answers you need quickly...and regular online updates keep you absolutely current. Leading international experts equip you with peerless advice and global best practices to enhance your diagnosis and management of a full range of immunologic problems. A highly clinical focus and an extremely practical organization expedite access to the answers you need in your daily practice. Cutting-edge coverage of the human genome project, immune-modifier drugs, and many other vital updates keeps you at the forefront of your field. A new organization places scientific and clinical material side by side, to simplify your research and highlight the clinical relevance of the topics covered. A multimedia format allows you to find information conveniently, both inside the exceptionally user-friendly book and at the fully searchable companion web site. Regular updates online ensure that you'll always have the latest knowledge at your fingertips. Includes many new and improved illustrations and four color design. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.
Harvard University Bulletin
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 388
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 388
Book Description
Harvard University Bulletin
Author: Harvard University
Publisher:
ISBN:
Category :
Languages : en
Pages : 820
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 820
Book Description
Bulletin of More Important Accessions with Bibliographical Contributions
Author: Justin Winsor
Publisher:
ISBN:
Category :
Languages : en
Pages : 392
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 392
Book Description
Host and Microbe Adaptations in the Evolution of Immunity
Author: Larry J. Dishaw
Publisher: Frontiers Media SA
ISBN: 2889630226
Category :
Languages : en
Pages : 254
Book Description
The evolution of metazoans has been accompanied by new interfaces with the microbial environment that include biological barriers and surveillance by specialized cell types. Increasingly complex organisms require increased capacities to confront pathogens, achieved by co-evolution of recognition mechanisms and regulatory pathways. Two distinct but interactive forms of immunity have evolved. Innate immunity, shared by all metazoans, is traditionally viewed as simple and non-specific. Adaptive immunity possesses the capacity to anticipate new infectious challenges and recall previous exposures; the most well-understood example of such a system, exhibited by lymphocytes of vertebrates, is based on somatic gene alterations that generate extraordinary specificity in discrimination of molecular structures. Our understanding of immune phylogeny over the past decades has tried to reconcile immunity from a vertebrate standpoint. While informative, such approaches cannot completely address the complex nature of selective pressures brought to bear by the complex microbiota (including pathogens) that co-exist with all metazoans. In recent years, comparative studies (and new technologies) have broadened our concepts of immunity from a systems-wide perspective. Unexpected findings, e.g., genetic expansions of innate receptors, high levels of polymorphism, RNA-based forms of generating diversity, adaptive evolution and functional divergence of gene families and the recognition of novel mediators of adaptive immunity, prompt us to reconsider the very nature of immunity. Even fundamental paradigms as to how the jawed vertebrate adaptive immune system should be structured for “optimal” recognition potential have been disrupted more than once (e.g., the discovery of the multicluster organization and germline joining of immunoglobulin genes in sharks, gene conversion as a mechanism of somatic diversification, absence of IgM or MHC II in certain teleost fishes). Mechanistically, concepts of innate immune memory, often referred to as “trained memory,” have been realized further, with the development of new discoveries in studies of epigenetic regulation of somatic lineages. Immune systems innovate and adapt in a taxon-specific manner, driven by the complexity of interactions with microbial symbionts (commensals, mutualists and pathogens). Immune systems are shaped by selective forces that reflect consequences of dynamic interactions with microbial environments as well as a capacity for rapid change that can be facilitated by genomic instabilities. We have learned that characterizing receptors and receptor interactions is not necessarily the most significant component in understanding the evolution of immunity. Rather, such a subject needs to be understood from a more global perspective and will necessitate re-consideration of the physical barriers that afford protection and the developmental processes that create them. By far, the most significant paradigm shifts in our understanding of immunity and the infection process has been that microbes no longer are considered to be an automatic cause or consequence of illness, but rather integral components of normal physiology and homeostasis. Immune phylogeny has been shaped not only by an arms race with pathogens but also perhaps by mutualistic interactions with resident microbes. This Research Topic updates and extends the previous eBook on Changing Views of the Evolution of Immunity and contains peer-reviewed submissions of original research, reviews and opinions.
Publisher: Frontiers Media SA
ISBN: 2889630226
Category :
Languages : en
Pages : 254
Book Description
The evolution of metazoans has been accompanied by new interfaces with the microbial environment that include biological barriers and surveillance by specialized cell types. Increasingly complex organisms require increased capacities to confront pathogens, achieved by co-evolution of recognition mechanisms and regulatory pathways. Two distinct but interactive forms of immunity have evolved. Innate immunity, shared by all metazoans, is traditionally viewed as simple and non-specific. Adaptive immunity possesses the capacity to anticipate new infectious challenges and recall previous exposures; the most well-understood example of such a system, exhibited by lymphocytes of vertebrates, is based on somatic gene alterations that generate extraordinary specificity in discrimination of molecular structures. Our understanding of immune phylogeny over the past decades has tried to reconcile immunity from a vertebrate standpoint. While informative, such approaches cannot completely address the complex nature of selective pressures brought to bear by the complex microbiota (including pathogens) that co-exist with all metazoans. In recent years, comparative studies (and new technologies) have broadened our concepts of immunity from a systems-wide perspective. Unexpected findings, e.g., genetic expansions of innate receptors, high levels of polymorphism, RNA-based forms of generating diversity, adaptive evolution and functional divergence of gene families and the recognition of novel mediators of adaptive immunity, prompt us to reconsider the very nature of immunity. Even fundamental paradigms as to how the jawed vertebrate adaptive immune system should be structured for “optimal” recognition potential have been disrupted more than once (e.g., the discovery of the multicluster organization and germline joining of immunoglobulin genes in sharks, gene conversion as a mechanism of somatic diversification, absence of IgM or MHC II in certain teleost fishes). Mechanistically, concepts of innate immune memory, often referred to as “trained memory,” have been realized further, with the development of new discoveries in studies of epigenetic regulation of somatic lineages. Immune systems innovate and adapt in a taxon-specific manner, driven by the complexity of interactions with microbial symbionts (commensals, mutualists and pathogens). Immune systems are shaped by selective forces that reflect consequences of dynamic interactions with microbial environments as well as a capacity for rapid change that can be facilitated by genomic instabilities. We have learned that characterizing receptors and receptor interactions is not necessarily the most significant component in understanding the evolution of immunity. Rather, such a subject needs to be understood from a more global perspective and will necessitate re-consideration of the physical barriers that afford protection and the developmental processes that create them. By far, the most significant paradigm shifts in our understanding of immunity and the infection process has been that microbes no longer are considered to be an automatic cause or consequence of illness, but rather integral components of normal physiology and homeostasis. Immune phylogeny has been shaped not only by an arms race with pathogens but also perhaps by mutualistic interactions with resident microbes. This Research Topic updates and extends the previous eBook on Changing Views of the Evolution of Immunity and contains peer-reviewed submissions of original research, reviews and opinions.
The New Medicines
Author: Bernice Z. Schacter
Publisher: Bloomsbury Publishing USA
ISBN: 0313083258
Category : Science
Languages : en
Pages : 281
Book Description
Today, most people use prescription medications. Every year, the multi-billion dollar pharmaceutical industry produces new medicines that treat everything from arthritis to AIDS, from high cholesterol to depression. But, despite recent controversies regarding the safety of drugs, consumers know little about the medications that they ingest and inject. How are these new medicines invented? How do consumers know that drugs are safe and effective? How are they tested? Who regulates their production - and who watches the regulators? How do drug companies produce the vast quantities needed for the marketplace, and why do they market their drugs as they do? The New Medicines leads the reader through the maze of the modern drug industry - from bench to bedside - and provides consumers with a step-by-step understanding of how new medicines are created, approved, marketed, and sold. In addition to explaining how drugs reach the medicine cabinet, the author - an experienced researcher and teacher - provides the scientific and business background for understanding the current controversial issues surrounding new medicines, such as: The rise and fall of the COX-2 inhibitors, Vioxx and Celebrex, and the process by which they were invented, approved, and re-evaluated. The saga of the cancer drug Erbitux and its creator, the company Imclone, made famous as the centerpiece of the Martha Stewart insider-trading scandal. The strengths and weaknesses of the approval process of the Food and Drug Administration. The controversial new marketing techniques of the pharmaceutical industry. A balanced work that provides readers with an unbiased look at the drug industry, The New Medicines will answer the questions of anyone who has ever looked at a bottle of their prescription pills and wondered, how did that get here?
Publisher: Bloomsbury Publishing USA
ISBN: 0313083258
Category : Science
Languages : en
Pages : 281
Book Description
Today, most people use prescription medications. Every year, the multi-billion dollar pharmaceutical industry produces new medicines that treat everything from arthritis to AIDS, from high cholesterol to depression. But, despite recent controversies regarding the safety of drugs, consumers know little about the medications that they ingest and inject. How are these new medicines invented? How do consumers know that drugs are safe and effective? How are they tested? Who regulates their production - and who watches the regulators? How do drug companies produce the vast quantities needed for the marketplace, and why do they market their drugs as they do? The New Medicines leads the reader through the maze of the modern drug industry - from bench to bedside - and provides consumers with a step-by-step understanding of how new medicines are created, approved, marketed, and sold. In addition to explaining how drugs reach the medicine cabinet, the author - an experienced researcher and teacher - provides the scientific and business background for understanding the current controversial issues surrounding new medicines, such as: The rise and fall of the COX-2 inhibitors, Vioxx and Celebrex, and the process by which they were invented, approved, and re-evaluated. The saga of the cancer drug Erbitux and its creator, the company Imclone, made famous as the centerpiece of the Martha Stewart insider-trading scandal. The strengths and weaknesses of the approval process of the Food and Drug Administration. The controversial new marketing techniques of the pharmaceutical industry. A balanced work that provides readers with an unbiased look at the drug industry, The New Medicines will answer the questions of anyone who has ever looked at a bottle of their prescription pills and wondered, how did that get here?