Antimicrobial Research and One Health in Africa

Antimicrobial Research and One Health in Africa PDF Author: Akebe Luther King Abia
Publisher: Springer Nature
ISBN: 303123796X
Category : Science
Languages : en
Pages : 359

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Book Description
Antimicrobial resistance is recognised among the world’s most challenging problems. Despite its global spread, Africa, specifically sub-Saharan Africa, is the most affected by this malaise. Poor living conditions and inadequate access to sanitation and potable water supplies are among contributing factors that have influenced a high disease burden on the continent, requiring extensive antimicrobials. Weak health systems and the absence of firm policies further aggravate the problem, as the use of antimicrobials is mostly unregulated. The increasing demand for animal protein to meet the starving populations’ demands has also influenced the use of these antimicrobials, including those banned on other continents, for food animal production. The ripple effect of indiscriminate use in humans and animals is the massive discharge of antimicrobials, their residues, antimicrobial-resistant microorganisms and their associated genes into the environment. This 14-chapter unique masterpiece presents the AMR problem in African, addressing the various compartments of the One Health – humans, animals, and the environment, to illustrate the need for concerted efforts in the fight against AMR, especially in Africa. Authors from the four cardinal points present diverse aspects of AMR in Africa, starting with behavioural and social drivers of AMR in Africa. Antimicrobial stewardship in an African context is also discussed. AMR in humans is presented through studies on antibiotic-resistant neonates and nontyphoidal Salmonella infections and the clinical relevance of the genetics of viral resistance. Topics on AMR in mastitis, biosecurity in animal farming and the linkage between disinfectants and AMR are discussed. The environmental dimension of AMR is discussed, notably in the aquatic environment, and its implication for aquaculture and irrigation and using nanomaterials to treat polluted waters from such environments are highlighted. Finally, Africa’s rich floral diversity is portrayed as an eco-friendly and cost-effective approach to combat AMR. Hopefully, the work presented will spur greater collaboration between scientists, environmental, animal and human health practitioners, the general population, and policymakers to assimilate and implement the One Health approach to combating AMR, rather than working in silos on their various sectors

Antimicrobial Research and One Health in Africa

Antimicrobial Research and One Health in Africa PDF Author: Akebe Luther King Abia
Publisher: Springer Nature
ISBN: 303123796X
Category : Science
Languages : en
Pages : 359

Get Book Here

Book Description
Antimicrobial resistance is recognised among the world’s most challenging problems. Despite its global spread, Africa, specifically sub-Saharan Africa, is the most affected by this malaise. Poor living conditions and inadequate access to sanitation and potable water supplies are among contributing factors that have influenced a high disease burden on the continent, requiring extensive antimicrobials. Weak health systems and the absence of firm policies further aggravate the problem, as the use of antimicrobials is mostly unregulated. The increasing demand for animal protein to meet the starving populations’ demands has also influenced the use of these antimicrobials, including those banned on other continents, for food animal production. The ripple effect of indiscriminate use in humans and animals is the massive discharge of antimicrobials, their residues, antimicrobial-resistant microorganisms and their associated genes into the environment. This 14-chapter unique masterpiece presents the AMR problem in African, addressing the various compartments of the One Health – humans, animals, and the environment, to illustrate the need for concerted efforts in the fight against AMR, especially in Africa. Authors from the four cardinal points present diverse aspects of AMR in Africa, starting with behavioural and social drivers of AMR in Africa. Antimicrobial stewardship in an African context is also discussed. AMR in humans is presented through studies on antibiotic-resistant neonates and nontyphoidal Salmonella infections and the clinical relevance of the genetics of viral resistance. Topics on AMR in mastitis, biosecurity in animal farming and the linkage between disinfectants and AMR are discussed. The environmental dimension of AMR is discussed, notably in the aquatic environment, and its implication for aquaculture and irrigation and using nanomaterials to treat polluted waters from such environments are highlighted. Finally, Africa’s rich floral diversity is portrayed as an eco-friendly and cost-effective approach to combat AMR. Hopefully, the work presented will spur greater collaboration between scientists, environmental, animal and human health practitioners, the general population, and policymakers to assimilate and implement the One Health approach to combating AMR, rather than working in silos on their various sectors

Antimicrobial Resistance

Antimicrobial Resistance PDF Author: Mihai Mares
Publisher: BoD – Books on Demand
ISBN: 1839624329
Category : Medical
Languages : en
Pages : 210

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Book Description
Tackling the realities of the antimicrobial resistance (AMR) situation today is no longer uncommon. Many battles have been fought in the past since the discovery of antibiotics between man and microbes. In the tussle of new antibiotic modifications, the transmission of resistant genes, both vertically and horizontally unveils yet another resistant attribute for the microbe, for it only to be faced with a more powerful, wide spectrum antibiotic; the cycle continues-and the winner is yet to be known. This book aims to provide some insight into various molecular mechanisms, agricultural mitigation methods, and the One Health applications to maybe, just maybe, tip the scales towards us.

One Health

One Health PDF Author: Kevin Bardosh
Publisher: Routledge
ISBN: 1317334965
Category : Business & Economics
Languages : en
Pages : 267

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Book Description
Zoonotic diseases – pathogens transmitted from animals to people – offer particularly challenging problems for global health institutions and actors, given the complex social-ecological dynamics at play. New forms of risk caused by unprecedented global connectivity and rapid social and environmental change demand new approaches. ‘One Health’ highlights the need for collaboration across sectors and disciplines to tackle zoonotic diseases. However, there has been little exploration of how social, political and economic contexts influence efforts to ‘do’ One Health. This book fills this gap by offering a much needed political economy analysis of zoonosis research and policy. Through ethnographic, qualitative and quantitative data, the book draws together a diverse number of case studies. These include chapters exploring global narratives about One Health operationalization and prevailing institutional bottlenecks; the evolution of research networks over time; and the histories and politics behind conflicting disease control approaches. The themes from these chapters are further contextualized and expanded upon through country-specific case studies – from Kenya, Zambia, Nigeria, Ghana and Sierra Leone – exploring the translation of One Health research and policy into the African context. This book is a valuable resource for academic researchers, students and policy practitioners in the areas of global health, agriculture and development.

A one health priority research agenda for antimicrobial resistance

A one health priority research agenda for antimicrobial resistance PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240075925
Category : Medical
Languages : en
Pages : 60

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Book Description


Global Antimicrobial Resistance Surveillance System

Global Antimicrobial Resistance Surveillance System PDF Author: World Health Organization
Publisher:
ISBN: 9789241549400
Category : Medical
Languages : en
Pages : 0

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Book Description
"In May 2015, the Sixty-eighth World Health Assembly adopted the Global action plan on antimicrobial resistance, which reflects the global consensus that AMR poses a profound threat to human health. One of the five strategic objectives of the Global action plan is to strengthen the evidence base through enhanced global surveillance and research. The Global Antimicrobial Resistance Surveillance System (GLASS) has been developed to facilitate and encourage a standardized approach to AMR surveillance globally and in turn support the implementation of the Global action plan on antimicrobial resistance. This manual addresses the early phase of implementation of GLASS, focussing on surveillance of resistance in common human bacterial pathogens. The intended readership of this publication is public health professionals and health authorities responsible for national AMR surveillance. It outlines the GLASS standards and describes the road map for implementation of the system between 2015 and 2019. Further development of GLASS will be based on the lessons learnt during this period"--Publisher's description.

WHO guidelines on use of medically important antimicrobials in food-producing animals

WHO guidelines on use of medically important antimicrobials in food-producing animals PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9789241550130
Category : Business & Economics
Languages : en
Pages : 0

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Book Description
WHO has launched new guidelines on use of medically important antimicrobials in food-producing animals, recommending that farmers and the food industry stop using antibiotics routinely to promote growth and prevent disease in healthy animals. These guidelines aim to help preserve the effectiveness of antibiotics that are important for human medicine by reducing their use in animals.

One Health

One Health PDF Author: Ronald M. Atlas
Publisher: John Wiley & Sons
ISBN: 1555818439
Category : Medical
Languages : en
Pages : 332

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Book Description
Emerging infectious diseases are often due to environmental disruption, which exposes microbes to a different niche that selects for new virulence traits and facilitates transmission between animals and humans. Thus, health of humans also depends upon health of animals and the environment – a concept called One Health. This book presents core concepts, compelling evidence, successful applications, and remaining challenges of One Health approaches to thwarting the threat of emerging infectious disease. Written by scientists working in the field, this book will provide a series of "stories" about how disruption of the environment and transmission from animal hosts is responsible for emerging human and animal diseases. Explains the concept of One Health and the history of the One Health paradigm shift. Traces the emergence of devastating new diseases in both animals and humans. Presents case histories of notable, new zoonoses, including West Nile virus, hantavirus, Lyme disease, SARS, and salmonella. Links several epidemic zoonoses with the environmental factors that promote them. Offers insight into the mechanisms of microbial evolution toward pathogenicity. Discusses the many causes behind the emergence of antibiotic resistance. Presents new technologies and approaches for public health disease surveillance. Offers political and bureaucratic strategies for promoting the global acceptance of One Health.

Taking a Multisectoral One Health Approach : A Tripartite Guide to Addressing Zoonotic Diseases in Countries

Taking a Multisectoral One Health Approach : A Tripartite Guide to Addressing Zoonotic Diseases in Countries PDF Author: Food and Agriculture Organization of the United Nations
Publisher: Food & Agriculture Org.
ISBN: 9251312362
Category : Medical
Languages : en
Pages : 166

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Book Description
The 2018 FAO-OIE-WHO (Tripartite) zoonoses guide, “Taking A Multisectoral, One Health Approach: A Tripartite Guide to Addressing Zoonotic Diseases in Countries” (2018 TZG) is being jointly developed to provide member countries with practical guidance on OH approaches to build national mechanisms for multisectoral coordination, communication, and collaboration to address zoonotic disease threats at the animal-human-environment interface. The 2018 TZG updates and expands on the guidance in the one previous jointly-developed, zoonoses-specific guidance document: the 2008 Tripartite “Zoonotic Diseases: A Guide to Establishing Collaboration between Animal and Human Health Sectors at the Country Level”, developed in WHO South-East Asia Region and Western Pacific Region. The 2018 TZG supports building by countries of the resilience and capacity to address emerging and endemic zoonotic diseases such as avian influenza, rabies, Ebola, and Rift Valley fever, as well as food-borne diseases and antimicrobial resistance, and to minimize their impacts on health, livelihoods, and economies. It additionally supports country efforts to implement WHO International Health Regulations (2005) and OIE international standards, to address gaps identified through external and internal health system evaluations, and to achieve targets of the Sustainable Development Goals. The 2018 TZG provides relevant country ministries and agencies with lessons learned and good practices identified from country-level experiences in taking OH approaches for preparedness, prevention, detection and response to zoonotic disease threats, and provides guidance on multisectoral communication, coordination, and collaboration. It informs on regional and country-level OH activities and relevant unisectoral and multisectoral tools available for countries to use.

One Health, 2nd Edition

One Health, 2nd Edition PDF Author: Jakob Zinsstag
Publisher: CABI
ISBN: 1789242576
Category : Medical
Languages : en
Pages : 459

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Book Description
One Health, the concept of combined veterinary and human health, has now expanded beyond emerging infectious diseases and zoonoses to incorporate a wider suite of health issues. Retaining its interdisciplinary focus which combines theory with practice, this new edition illustrates the contribution of One Health collaborations to real-world issues such as sanitation, economics, food security and vaccination programmes. It includes more non-infectious disease issues and climate change discussion alongside revised case studies and expanded methodology chapters to draw out implications for practice. Promoting an action-based, solutions-oriented approach, One Health: The Theory and Practice of Integrated Health Approaches highlights the lessons learned for both human and animal health professionals and students.

The Evolving Threat of Antimicrobial Resistance

The Evolving Threat of Antimicrobial Resistance PDF Author: World Health Organization
Publisher:
ISBN: 9789241503181
Category : Medical
Languages : en
Pages : 0

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Book Description
Antibiotic resistance development is a natural process of adaption leading to a limited lifespan of antibiotics. Unnecessary and inappropriate use of antibiotics favours the emergence and spread of resistant bacteria. A crisis has been building up over decades, so that today common and life-threatening infections are becoming difficult or even impossible to treat. It is time to take much stronger action worldwide to avert an ever increasing health and economic burden. A new WHO publication "The evolving threat of antimicrobial resistance--Options for action" describes examples of policy activities that have addressed AMR in different parts of the world. The aim is to raise awareness and to stimulate further coordinated efforts.