Author: Barry Werth
Publisher: Simon and Schuster
ISBN: 145165569X
Category : Business & Economics
Languages : en
Pages : 448
Book Description
In this timely and much praised book, Barry Werth draws upon inside reporting that spans more than two decades. He provides a groundbreaking close-up of the upstart pharmaceutical company Vertex and the ferocious but indispensable world of Big Pharma that it inhabits. In 1989, the charismatic Joshua Boger left Merck, then America’s most admired business, to found a drug company that would challenge industry giants and transform health care. Werth described the company’s tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex’s bold endurance and eventual success. The $325 billion-a-year pharmaceutical business is America’s toughest and one of its most profitable. It’s riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine even after a molecule clears all the hurdles to get to human testing; to the multibillion-dollar cost of ramping up a successful product; to operating in the world’s most regulated industry, matched only by nuclear power. Werth captures the full scope of Vertex’s twenty-five-year drive to deliver breakthrough medicines. At a time when America struggles to maintain its innovative edge, The Antidote is a powerful inside look at one of the most intriguing and important business stories of recent decades.
The Antidote
Author: Barry Werth
Publisher: Simon and Schuster
ISBN: 145165569X
Category : Business & Economics
Languages : en
Pages : 448
Book Description
In this timely and much praised book, Barry Werth draws upon inside reporting that spans more than two decades. He provides a groundbreaking close-up of the upstart pharmaceutical company Vertex and the ferocious but indispensable world of Big Pharma that it inhabits. In 1989, the charismatic Joshua Boger left Merck, then America’s most admired business, to found a drug company that would challenge industry giants and transform health care. Werth described the company’s tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex’s bold endurance and eventual success. The $325 billion-a-year pharmaceutical business is America’s toughest and one of its most profitable. It’s riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine even after a molecule clears all the hurdles to get to human testing; to the multibillion-dollar cost of ramping up a successful product; to operating in the world’s most regulated industry, matched only by nuclear power. Werth captures the full scope of Vertex’s twenty-five-year drive to deliver breakthrough medicines. At a time when America struggles to maintain its innovative edge, The Antidote is a powerful inside look at one of the most intriguing and important business stories of recent decades.
Publisher: Simon and Schuster
ISBN: 145165569X
Category : Business & Economics
Languages : en
Pages : 448
Book Description
In this timely and much praised book, Barry Werth draws upon inside reporting that spans more than two decades. He provides a groundbreaking close-up of the upstart pharmaceutical company Vertex and the ferocious but indispensable world of Big Pharma that it inhabits. In 1989, the charismatic Joshua Boger left Merck, then America’s most admired business, to found a drug company that would challenge industry giants and transform health care. Werth described the company’s tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex’s bold endurance and eventual success. The $325 billion-a-year pharmaceutical business is America’s toughest and one of its most profitable. It’s riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine even after a molecule clears all the hurdles to get to human testing; to the multibillion-dollar cost of ramping up a successful product; to operating in the world’s most regulated industry, matched only by nuclear power. Werth captures the full scope of Vertex’s twenty-five-year drive to deliver breakthrough medicines. At a time when America struggles to maintain its innovative edge, The Antidote is a powerful inside look at one of the most intriguing and important business stories of recent decades.
The Practitioner
Author:
Publisher:
ISBN:
Category : Family medicine
Languages : en
Pages : 1034
Book Description
Publisher:
ISBN:
Category : Family medicine
Languages : en
Pages : 1034
Book Description
A Creature of the Night
Author: Fergus Hume
Publisher: BoD – Books on Demand
ISBN: 3752352116
Category : Fiction
Languages : en
Pages : 122
Book Description
Reproduction of the original: A Creature of the Night by Fergus Hume
Publisher: BoD – Books on Demand
ISBN: 3752352116
Category : Fiction
Languages : en
Pages : 122
Book Description
Reproduction of the original: A Creature of the Night by Fergus Hume
GHETTOCLAUSTROPHOBIA
Author: Shanta Lee Gander
Publisher: Diode Editions
ISBN: 1939728401
Category : Poetry
Languages : en
Pages : 103
Book Description
What does it mean to move away from the shadow of one’s mother, parents, or family in order to come into being within this world? As collective memory within the Black diaspora has been ruptured, GHETTOCLAUSTROPHOBIA time travels by creating and recapturing memory from a fractured past to survive in the present and envision a future. In her first full-length collection GHETTOCLAUSTROPHOBIA: Dreamin of Mama While Trying to Speak Woman in Woke Tongues, Shanta Lee Gander navigates between formal and vernacular styles to introduce the reader to a myriad of subjects such as scientific facts that link butterflies to female sexuality and vulnerability; whispers of classical Greek myth; H.P. Lovecraft’s fantastical creature, Cthulhu; and the traces of African mythmaking and telling. Beneath the intensity, longing, seeking, wondering, and the ‘tell-it-like-it-is’ voice that sometimes tussles with sadness, there is a movement of sass and a will that refuses to say that it has been broken. Gander leaves a door ajar in this ongoing conversation of the Black female body that walks the spaces of the individual within a collective; the tensions between inherited and hidden narratives; and the present within a history and future that is still being imagined.
Publisher: Diode Editions
ISBN: 1939728401
Category : Poetry
Languages : en
Pages : 103
Book Description
What does it mean to move away from the shadow of one’s mother, parents, or family in order to come into being within this world? As collective memory within the Black diaspora has been ruptured, GHETTOCLAUSTROPHOBIA time travels by creating and recapturing memory from a fractured past to survive in the present and envision a future. In her first full-length collection GHETTOCLAUSTROPHOBIA: Dreamin of Mama While Trying to Speak Woman in Woke Tongues, Shanta Lee Gander navigates between formal and vernacular styles to introduce the reader to a myriad of subjects such as scientific facts that link butterflies to female sexuality and vulnerability; whispers of classical Greek myth; H.P. Lovecraft’s fantastical creature, Cthulhu; and the traces of African mythmaking and telling. Beneath the intensity, longing, seeking, wondering, and the ‘tell-it-like-it-is’ voice that sometimes tussles with sadness, there is a movement of sass and a will that refuses to say that it has been broken. Gander leaves a door ajar in this ongoing conversation of the Black female body that walks the spaces of the individual within a collective; the tensions between inherited and hidden narratives; and the present within a history and future that is still being imagined.
The Medical World
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 622
Book Description
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 622
Book Description
Defy the Night
Author: Brigid Kemmerer
Publisher: Bloomsbury Publishing USA
ISBN: 1547604670
Category : Young Adult Fiction
Languages : en
Pages : 483
Book Description
Instant New York Times Bestseller! From New York Times bestselling author Brigid Kemmerer comes an electrifying fantasy romance, perfect for fans of Holly Black and Victoria Aveyard. A desperate prince. A daring outlaw. A dangerous flirtation. In the Wilds of Kandala, apothecary apprentice Tessa Cade has been watching people suffer for too long. A mysterious sickness is ravaging the land and the cure, Moonflower Elixir, is only available for the wealthy. So every night, she defies the royal edicts and sneaks out, stealing Moonflower petals and leaving the elixir for those in need. In the palace of Kandala, Prince Corrick serves as the King's Justice, meting out vicious punishments and striking fear into the hearts of agitators and outlaws. Corrick knows he must play this role convincingly--with a shortage of elixir and threats of rebellion looming ever closer, the King's grip on power is tenuous at best, and Corrick knows his brother is the kingdom's best hope for survival. But when an act of unspeakable cruelty brings the royal and the outlaw face to face, the natural enemies are faced with an impossible choice--and a surprising spark. Will they follow their instincts to destroy each other? Or will they save the kingdom together . . . and let that spark ignite?
Publisher: Bloomsbury Publishing USA
ISBN: 1547604670
Category : Young Adult Fiction
Languages : en
Pages : 483
Book Description
Instant New York Times Bestseller! From New York Times bestselling author Brigid Kemmerer comes an electrifying fantasy romance, perfect for fans of Holly Black and Victoria Aveyard. A desperate prince. A daring outlaw. A dangerous flirtation. In the Wilds of Kandala, apothecary apprentice Tessa Cade has been watching people suffer for too long. A mysterious sickness is ravaging the land and the cure, Moonflower Elixir, is only available for the wealthy. So every night, she defies the royal edicts and sneaks out, stealing Moonflower petals and leaving the elixir for those in need. In the palace of Kandala, Prince Corrick serves as the King's Justice, meting out vicious punishments and striking fear into the hearts of agitators and outlaws. Corrick knows he must play this role convincingly--with a shortage of elixir and threats of rebellion looming ever closer, the King's grip on power is tenuous at best, and Corrick knows his brother is the kingdom's best hope for survival. But when an act of unspeakable cruelty brings the royal and the outlaw face to face, the natural enemies are faced with an impossible choice--and a surprising spark. Will they follow their instincts to destroy each other? Or will they save the kingdom together . . . and let that spark ignite?
Mechanics' and Engineers' Pocketbook of Tables, Rules, and Formulas Pertaining to Mechanics, Mathematics, and Physics ...
Author: Charles Haynes Haswell
Publisher:
ISBN:
Category : Engineering
Languages : en
Pages : 966
Book Description
Publisher:
ISBN:
Category : Engineering
Languages : en
Pages : 966
Book Description
Mechanics' and Engineers' Pocketbook of Tables
Author: Charles Haynes Haswell
Publisher:
ISBN:
Category : Engineering
Languages : en
Pages : 990
Book Description
Publisher:
ISBN:
Category : Engineering
Languages : en
Pages : 990
Book Description
Mechanics' and Engineers' Pocket-book of Tables, Rules, and Formulas Pertaining to Mechanics, Mathematics, and Physics ...
Author: Charles Haynes Haswell
Publisher:
ISBN:
Category : Engineering
Languages : en
Pages : 1092
Book Description
Publisher:
ISBN:
Category : Engineering
Languages : en
Pages : 1092
Book Description
A Creature of the Night: An Italian Enigma
Author: Fergus Hume
Publisher: Good Press
ISBN:
Category : Fiction
Languages : en
Pages : 139
Book Description
'A Creature of the Night: An Italian Enigma' is a mystery-supernatural novel by Fergus Hume. The story follows the narrator, a member of the Cranstons family, who travels to Italy with a few hundred pounds and a dream of pursuing an operatic career. He settles in Milan and takes singing lessons from Maestro Angello, who later goes to Verona for a change of scenery. The novel sets the scene for a gripping mystery with supernatural elements, as the narrator uncovers secrets about Angello's past and encounters a mysterious and possibly dangerous creature of the night.
Publisher: Good Press
ISBN:
Category : Fiction
Languages : en
Pages : 139
Book Description
'A Creature of the Night: An Italian Enigma' is a mystery-supernatural novel by Fergus Hume. The story follows the narrator, a member of the Cranstons family, who travels to Italy with a few hundred pounds and a dream of pursuing an operatic career. He settles in Milan and takes singing lessons from Maestro Angello, who later goes to Verona for a change of scenery. The novel sets the scene for a gripping mystery with supernatural elements, as the narrator uncovers secrets about Angello's past and encounters a mysterious and possibly dangerous creature of the night.