Author: Victor Lorian
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781749831
Category : Medical
Languages : en
Pages : 924
Book Description
Implement the most current science and practice in antimicrobial research. Now, find the newest approaches for evaluating the activity, mechanisms of action, and bacterial resistance to antibiotics with this completely updated, landmark reference. Turn to this comprehensive reference for groundbreaking evidence on the molecular link between chemical disinfectants, sterilants, and antibiotics. On the latest methods for detecting antibacterial resistance genes in the clinical laboratory, and antivirogram use to select the most active antiviral components against your patient's HIV.
Antibiotics in Laboratory Medicine
Antibiotics in Laboratory Medicine
Author: Daniel Amsterdam
Publisher: Lippincott Williams & Wilkins
ISBN: 1469883635
Category : Medical
Languages : en
Pages : 1196
Book Description
Antibiotics in Laboratory Medicine has been a mainstay resource for practitioners/providers, investigators, and pharmaceutical researchers of new anti-infective compounds for the past 30 years. This edition includes new chapters on the predictive value of in vitro laboratory testing and the improvement of patient care in the hospital environment through antimicrobial stewardship.
Publisher: Lippincott Williams & Wilkins
ISBN: 1469883635
Category : Medical
Languages : en
Pages : 1196
Book Description
Antibiotics in Laboratory Medicine has been a mainstay resource for practitioners/providers, investigators, and pharmaceutical researchers of new anti-infective compounds for the past 30 years. This edition includes new chapters on the predictive value of in vitro laboratory testing and the improvement of patient care in the hospital environment through antimicrobial stewardship.
Antibiotics in Laboratory Medicine
Author: Victor Lorian
Publisher:
ISBN:
Category : Microbial sensitivity tests
Languages : en
Pages : 737
Book Description
Publisher:
ISBN:
Category : Microbial sensitivity tests
Languages : en
Pages : 737
Book Description
Antibiotics in laboratory medicine. 5th ed
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Antibiotics
Author: Christopher Walsh
Publisher: John Wiley & Sons
ISBN: 1555819311
Category : Medical
Languages : en
Pages : 477
Book Description
A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets. This textbook details how classes of antibiotics interact with five known robust bacterial targets: cell wall assembly and maintenance, membrane integrity, protein synthesis, DNA and RNA information transfer, and the folate pathway to deoxythymidylate. It also addresses the universe of bacterial resistance, from the concept of the resistome to the three major mechanisms of resistance: antibiotic destruction, antibiotic active efflux, and alteration of antibiotic targets. Antibiotics also covers the biosynthetic machinery for the major classes of natural product antibiotics. Authors Christopher Walsh and Timothy Wencewicz provide compelling answers to these questions: What are antibiotics? Where do antibiotics come from? How do antibiotics work? Why do antibiotics stop working? How should our limited inventory of effective antibiotics be addressed? Antibiotics is a textbook for graduate courses in chemical biology, pharmacology, medicinal chemistry, and microbiology and biochemistry courses. It is also a valuable reference for microbiologists, biological and natural product chemists, pharmacologists, and research and development scientists.
Publisher: John Wiley & Sons
ISBN: 1555819311
Category : Medical
Languages : en
Pages : 477
Book Description
A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets. This textbook details how classes of antibiotics interact with five known robust bacterial targets: cell wall assembly and maintenance, membrane integrity, protein synthesis, DNA and RNA information transfer, and the folate pathway to deoxythymidylate. It also addresses the universe of bacterial resistance, from the concept of the resistome to the three major mechanisms of resistance: antibiotic destruction, antibiotic active efflux, and alteration of antibiotic targets. Antibiotics also covers the biosynthetic machinery for the major classes of natural product antibiotics. Authors Christopher Walsh and Timothy Wencewicz provide compelling answers to these questions: What are antibiotics? Where do antibiotics come from? How do antibiotics work? Why do antibiotics stop working? How should our limited inventory of effective antibiotics be addressed? Antibiotics is a textbook for graduate courses in chemical biology, pharmacology, medicinal chemistry, and microbiology and biochemistry courses. It is also a valuable reference for microbiologists, biological and natural product chemists, pharmacologists, and research and development scientists.
Beta-lactam Antibiotics in Laboratory Medicine
Author: Ika Ningsih
Publisher:
ISBN:
Category :
Languages : en
Pages : 84
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 84
Book Description
Antimicrobial Susceptibility Testing Protocols
Author: Richard Schwalbe
Publisher: CRC Press
ISBN: 1420014498
Category : Medical
Languages : fr
Pages : 430
Book Description
The clinical microbiology laboratory is often a sentinel for the detection of drug resistant strains of microorganisms. Standardized protocols require continual scrutiny to detect emerging phenotypic resistance patterns. The timely notification of clinicians with susceptibility results can initiate the alteration of antimicrobial chemotherapy and
Publisher: CRC Press
ISBN: 1420014498
Category : Medical
Languages : fr
Pages : 430
Book Description
The clinical microbiology laboratory is often a sentinel for the detection of drug resistant strains of microorganisms. Standardized protocols require continual scrutiny to detect emerging phenotypic resistance patterns. The timely notification of clinicians with susceptibility results can initiate the alteration of antimicrobial chemotherapy and
Polymyxin Antibiotics
Author: Jian Li (Pharmacologist)
Publisher:
ISBN: 9783030163723
Category : Antibiotics
Languages : en
Pages :
Book Description
It is our wish that readers discover the importance of polymyxin structure in relation to the mechanisms of activity, resistance and toxicity. We emphasized that reliable analytic methods for polymyxins are critical when investigating their pharmacokinetics (PK) and pharmacodynamics (PD). The complicated dose definitions and different pharmacopoeial standards have already compromised the safe use of polymyxins in patients. Therefore, informed by the latest pharmacological information, scientifically-based dosing recommendations have been proposed for intravenous polymyxins. Considering the PK/PD limitations and potential development of resistance, polymyxin combinations are encouraged; however, the current literature has not shown definite microbiological benefits, possibly because most clinical studies to date overlooked key PK/PD principles. Nephrotoxicity is the major dose-limiting factor and it is imperative to elucidate the mechanisms and develop novel approaches to minimize polymyxin-associated toxicities. In addition, the anti-endotoxin effect of polymyxins supports their clinical use to treat Gram-negative sepsis. Fortunately, the discovery of new-generation polymyxins with wider therapeutic windows has benefited from the latest achievements in polymyxin research.
Publisher:
ISBN: 9783030163723
Category : Antibiotics
Languages : en
Pages :
Book Description
It is our wish that readers discover the importance of polymyxin structure in relation to the mechanisms of activity, resistance and toxicity. We emphasized that reliable analytic methods for polymyxins are critical when investigating their pharmacokinetics (PK) and pharmacodynamics (PD). The complicated dose definitions and different pharmacopoeial standards have already compromised the safe use of polymyxins in patients. Therefore, informed by the latest pharmacological information, scientifically-based dosing recommendations have been proposed for intravenous polymyxins. Considering the PK/PD limitations and potential development of resistance, polymyxin combinations are encouraged; however, the current literature has not shown definite microbiological benefits, possibly because most clinical studies to date overlooked key PK/PD principles. Nephrotoxicity is the major dose-limiting factor and it is imperative to elucidate the mechanisms and develop novel approaches to minimize polymyxin-associated toxicities. In addition, the anti-endotoxin effect of polymyxins supports their clinical use to treat Gram-negative sepsis. Fortunately, the discovery of new-generation polymyxins with wider therapeutic windows has benefited from the latest achievements in polymyxin research.
An Introduction to Immunocytochemistry
Author: Julia M. Polak
Publisher: Oxford University Press, USA
ISBN:
Category : Architecture
Languages : en
Pages : 76
Book Description
This work gives a concise exposition of the different immunocytochemical methods for identifying tissue constituents. It discusses ways of preparing tissues according to the antigen to be localized, and most commonly used methods, sources of error and nonspecifity, and techniques for recording results photographically.
Publisher: Oxford University Press, USA
ISBN:
Category : Architecture
Languages : en
Pages : 76
Book Description
This work gives a concise exposition of the different immunocytochemical methods for identifying tissue constituents. It discusses ways of preparing tissues according to the antigen to be localized, and most commonly used methods, sources of error and nonspecifity, and techniques for recording results photographically.
Oxford Handbook of Infectious Diseases and Microbiology
Author: Estée Török
Publisher: Oxford University Press
ISBN: 019967132X
Category : Anti-infective agents
Languages : en
Pages : 914
Book Description
This handbook takes an integrated approach to both infectious disease and microbiology. Referenced to national frameworks and current legislation, it covers basic principles of bacteriology and virology, specific information on diseases and conditions, and material on 'hot topics' such as bioterrorism and preventative medicine.
Publisher: Oxford University Press
ISBN: 019967132X
Category : Anti-infective agents
Languages : en
Pages : 914
Book Description
This handbook takes an integrated approach to both infectious disease and microbiology. Referenced to national frameworks and current legislation, it covers basic principles of bacteriology and virology, specific information on diseases and conditions, and material on 'hot topics' such as bioterrorism and preventative medicine.