Annual Review of Physical Chemistry

Annual Review of Physical Chemistry PDF Author: B. S. Rabinovitch
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 664

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Book Description

Annual Review of Physical Chemistry

Annual Review of Physical Chemistry PDF Author: B. S. Rabinovitch
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 664

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Book Description


Drug Safety Evaluation

Drug Safety Evaluation PDF Author: Shayne Cox Gad
Publisher: John Wiley & Sons
ISBN: 1119097401
Category : Medical
Languages : en
Pages : 918

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Book Description
This practical guide presents a road map for safety assessment as an integral part of the development of new drugs and therapeutics. Helps readers solve scientific, technical, and regulatory issues in preclinical safety assessment and early clinical drug development Explains scientific and philosophical bases for evaluation of specific concerns – including local tissue tolerance, target organ toxicity and carcinogenicity, developmental toxicity, immunogenicity, and immunotoxicity Covers the development of new small and large molecules, generics, 505(b)(2) route NDAs, and biosimilars Revises material to reflect new drug products (small synthetic, large proteins and cells, and tissues), harmonized global and national regulations, and new technologies for safety evaluation Adds almost 20% new and thoroughly updates existing content from the last edition

Clarke's Analytical Forensic Toxicology

Clarke's Analytical Forensic Toxicology PDF Author: Gail Cooper
Publisher: Pharmaceutical Press
ISBN: 0857110543
Category : Law
Languages : en
Pages : 657

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Book Description
This invaluable textbook, written by international experts, covers all the main elements of forensic toxicology and analytical toxicology techniques as well as the important parts of pharmacokinetics, drug metabolism, and pharmacology in general, with a particular focus on drugs of abuse.

Principles of Safety Pharmacology

Principles of Safety Pharmacology PDF Author: Michael K. Pugsley
Publisher: Springer
ISBN: 366246943X
Category : Medical
Languages : en
Pages : 477

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Book Description
This book illustrates, in a comprehensive manner, the most current areas of importance to Safety Pharmacology, a burgeoning unique pharmacological discipline with important ties to academia, industry and regulatory authorities. It provides readers with a definitive collection of topics containing essential information on the latest industry guidelines and overviews current and breakthrough topics in both functional and molecular pharmacology. An additional novelty of the book is that it constitutes academic, pharmaceutical and biotechnology perspectives for Safety Pharmacology issues. Each chapter is written by an expert in the area and includes not only a fundamental background regarding the topic but also detailed descriptions of currently accepted, validated models and methods as well as innovative methodologies used in drug discovery.

The Review of Natural Products

The Review of Natural Products PDF Author: Ara DerMarderosian
Publisher:
ISBN: 9781574392258
Category : Materia medica
Languages : en
Pages : 0

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Book Description
The Review of Natural Products is the foremost source of current natural product information for health care professionals. More than 300 in-depth monographs are included, based on scientific research, not just anecdotal information. The Review of Natural Products provides detailed information about natural products, including their botany, history, chemistry, pharmacology, medicinal uses, toxicology, and patient information. It also includes significantly documented drug interactions.

Wall & Melzack's Textbook of Pain

Wall & Melzack's Textbook of Pain PDF Author: Stephen McMahon, FMedSci, FSB
Publisher: Elsevier Health Sciences
ISBN: 0702040592
Category : Medical
Languages : en
Pages : 1507

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Book Description
2014 BMA Medical Book Awards Highly Commended in Anaesthesia category! Apply the latest scientific and clinical advances with Wall & Melzack's Textbook of Pain, 6th Edition. Drs. Stephen McMahon, Martin Koltzenburg, Irene Tracey, and Dennis C. Turk, along with more than 125 other leading authorities, present all of the latest knowledge about the genetics, neurophysiology, psychology, and assessment of every type of pain syndrome. They also provide practical guidance on the full range of today's pharmacologic, interventional, electrostimulative, physiotherapeutic, and psychological management options. Benefit from the international, multidisciplinary knowledge and experience of a "who's who" of international authorities in pain medicine, neurology, neurosurgery, neuroscience, psychiatry, psychology, physical medicine and rehabilitation, palliative medicine, and other relevant fields. Access the complete contents online anytime, anywhere at www.expertconsult.com. Translate scientific findings into clinical practice with updates on the genetics of pain, new pharmacologic and treatment information, and much more. Easily visualize important scientific concepts with a high-quality illustration program, now in full color throughout. Choose the safest and most effective management methods with expanded coverage of anesthetic techniques. Stay abreast of the latest global developments regarding opioid induced hyperalgesia, addiction and substance abuse, neuromodulation and pain management, identification of specific targets for molecular pain, and other hot topics.

Pain Management and the Opioid Epidemic

Pain Management and the Opioid Epidemic PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309459575
Category : Medical
Languages : en
Pages : 483

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Book Description
Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Blood Sugar

Blood Sugar PDF Author: Anthony Ryan Hatch
Publisher: U of Minnesota Press
ISBN: 1452950075
Category : Social Science
Languages : en
Pages : 191

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Book Description
Why do African Americans have exceptionally high rates of hypertension, diabetes, and obesity? Is it their genes? Their disease-prone culture? Their poor diets? Such racist explanations for racial inequalities in metabolic health have circulated in medical journals for decades. Blood Sugar analyzes and challenges the ways in which “metabolic syndrome” has become a major biomedical category that medical researchers have created to better understand the risks high blood pressure, blood sugar, body fat, and cholesterol pose to people. An estimated sixty million Americans are well on the way to being diagnosed with it, many of them belonging to people of color. Anthony Ryan Hatch argues that the syndrome represents another, very real crisis and that its advent signals a new form of “colorblind scientific racism”—a repackaging of race within biomedical and genomic research. Examining the cultural discussions and scientific practices that target human metabolism of prescription drugs and sugar by African Americans, he reveals how medical researchers who use metabolic syndrome to address racial inequalities in health have in effect reconstructed race as a fixed, biological, genetic feature of bodies—without incorporating social and economic inequalities into the equation. And just as the causes of metabolic syndrome are framed in racial terms, so are potential drug treatments and nutritional health interventions. The first sustained social and political inquiry of metabolic syndrome, this provocative and timely book is a crucial contribution to the emerging literature on race and medicine. It will engage those who seek to understand how unjust power relations shape population health inequalities and the production of medical knowledge and biotechnologies.

Introduction to Basics of Pharmacology and Toxicology

Introduction to Basics of Pharmacology and Toxicology PDF Author: Gerard Marshall Raj
Publisher: Springer Nature
ISBN: 9813297794
Category : Medical
Languages : en
Pages : 410

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Book Description
This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases. Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.

Merck's Index

Merck's Index PDF Author:
Publisher:
ISBN:
Category : Biomolecules
Languages : en
Pages : 496

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Book Description