Analysis of the Structure and Function of Human DNA Polymerase Lambda PDF Download
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Category :
Languages : en
Pages : 412
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Author:
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ISBN:
Category :
Languages : en
Pages : 412
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Author: Francis Mwai Kariuki
Publisher:
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Category :
Languages : en
Pages : 166
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Author: Barry Jon Coull
Publisher:
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Category :
Languages : en
Pages : 412
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Author: Giovanni Maga
Publisher: World Scientific
ISBN: 9813226420
Category : Science
Languages : en
Pages : 398
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Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their tasks in vivo, DNA polymerases are the workhorses in numerous biotechnology applications such as the polymerase chain reaction (PCR), cDNA cloning, next generation sequencing, nucleic acids based diagnostics and in techniques to analyze ancient and otherwise damaged DNA (e.g. for forensic applications). Moreover, some diseases are related to DNA polymerase defects and chemotherapy through inhibition of DNA polymerases is used to fight HIV, Herpes and Hepatitis B and C infections. This book focuses on (i) biology of DNA polymerases, (ii) medical aspects of DNA polymerases and (iii) biotechnological applications of DNA polymerases. It is intended for a wide audience from basic scientists, to diagnostic laboratories, to companies and to clinicians, who seek a better understanding and the practical use of these fascinating enzymes.
![Structure-function Studies of DNA Polymerase [lambda] PDF](https://books.google.com/books/content/images/frontcover/aefjoAEACAAJ?fife=w80-h100)
Author: Amber Dianne Frick
Publisher:
ISBN:
Category : DNA polymerases
Languages : en
Pages : 68
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Author: Renee Ann Beardslee
Publisher:
ISBN:
Category :
Languages : en
Pages : 145
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Author: Ulrich Hübscher
Publisher: World Scientific
ISBN: 9814299170
Category : Medical
Languages : en
Pages : 338
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Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their tasks in vivo, DNA polymerases are the workhorses in numerous biotechnology applications such as the polymerase chain reaction (PCR), cDNA cloning, genome sequencing, nucleic acids-based diagnostics and in techniques to analyze ancient and otherwise damaged DNA. Moreover, some diseases are related to DNA polymerase defects, and chemotherapy through inhibition of DNA polymerases is used to fight HIV, Herpes and Hepatitis B and C infections. We have recently witnessed the discovery of an abundance of novel DNA polymerases in viruses, bacteria, archaea and eukaryotes with specialized properties whose physiological functions are only beginning to be understood. This book summarizes the current knowledge of these fascinating enzymes. It is intended for a wide audience from basic scientists, to diagnostic laboratories and to clinicians who seek a better understanding of these fascinating enzymes.
Author: Katsuhiko S. Murakami
Publisher: Springer Science & Business Media
ISBN: 3642397964
Category : Science
Languages : en
Pages : 342
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This book provides a review of the multitude of nucleic acid polymerases, including DNA and RNA polymerases from Archea, Bacteria and Eukaryota, mitochondrial and viral polymerases, and other specialized polymerases such as telomerase, template-independent terminal nucleotidyl transferase and RNA self-replication ribozyme. Although many books cover several different types of polymerases, no book so far has attempted to catalog all nucleic acid polymerases. The goal of this book is to be the top reference work for postgraduate students, postdocs, and principle investigators who study polymerases of all varieties. In other words, this book is for polymerase fans by polymerase fans. Nucleic acid polymerases play a fundamental role in genome replication, maintenance, gene expression and regulation. Throughout evolution these enzymes have been pivotal in transforming life towards RNA self-replicating systems as well as into more stable DNA genomes. These enzymes are generally extremely efficient and accurate in RNA transcription and DNA replication and share common kinetic and structural features. How catalysis can be so amazingly fast without loss of specificity is a question that has intrigued researchers for over 60 years. Certain specialized polymerases that play a critical role in cellular metabolism are used for diverse biotechnological applications and are therefore an essential tool for research.
![Structure-function Analysis of DNA Polymerase-[beta] Using Monoclonal Antibodies PDF](https://books.google.com/books/content/images/frontcover/genttwAACAAJ?fife=w80-h100)
Author: Anthony J. Recupero
Publisher:
ISBN:
Category :
Languages : en
Pages : 242
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ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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