Author: Sanghamitra Bandyopadhyay
Publisher: World Scientific
ISBN: 9814475122
Category : Computers
Languages : en
Pages : 353
Book Description
Bioinformatics, a field devoted to the interpretation and analysis of biological data using computational techniques, has evolved tremendously in recent years due to the explosive growth of biological information generated by the scientific community. Soft computing is a consortium of methodologies that work synergistically and provides, in one form or another, flexible information processing capabilities for handling real-life ambiguous situations. Several research articles dealing with the application of soft computing tools to bioinformatics have been published in the recent past; however, they are scattered in different journals, conference proceedings and technical reports, thus causing inconvenience to readers, students and researchers.This book, unique in its nature, is aimed at providing a treatise in a unified framework, with both theoretical and experimental results, describing the basic principles of soft computing and demonstrating the various ways in which they can be used for analyzing biological data in an efficient manner. Interesting research articles from eminent scientists around the world are brought together in a systematic way such that the reader will be able to understand the issues and challenges in this domain, the existing ways of tackling them, recent trends, and future directions. This book is the first of its kind to bring together two important research areas, soft computing and bioinformatics, in order to demonstrate how the tools and techniques in the former can be used for efficiently solving several problems in the latter.
Analysis Of Biological Data: A Soft Computing Approach
Author: Sanghamitra Bandyopadhyay
Publisher: World Scientific
ISBN: 9814475122
Category : Computers
Languages : en
Pages : 353
Book Description
Bioinformatics, a field devoted to the interpretation and analysis of biological data using computational techniques, has evolved tremendously in recent years due to the explosive growth of biological information generated by the scientific community. Soft computing is a consortium of methodologies that work synergistically and provides, in one form or another, flexible information processing capabilities for handling real-life ambiguous situations. Several research articles dealing with the application of soft computing tools to bioinformatics have been published in the recent past; however, they are scattered in different journals, conference proceedings and technical reports, thus causing inconvenience to readers, students and researchers.This book, unique in its nature, is aimed at providing a treatise in a unified framework, with both theoretical and experimental results, describing the basic principles of soft computing and demonstrating the various ways in which they can be used for analyzing biological data in an efficient manner. Interesting research articles from eminent scientists around the world are brought together in a systematic way such that the reader will be able to understand the issues and challenges in this domain, the existing ways of tackling them, recent trends, and future directions. This book is the first of its kind to bring together two important research areas, soft computing and bioinformatics, in order to demonstrate how the tools and techniques in the former can be used for efficiently solving several problems in the latter.
Publisher: World Scientific
ISBN: 9814475122
Category : Computers
Languages : en
Pages : 353
Book Description
Bioinformatics, a field devoted to the interpretation and analysis of biological data using computational techniques, has evolved tremendously in recent years due to the explosive growth of biological information generated by the scientific community. Soft computing is a consortium of methodologies that work synergistically and provides, in one form or another, flexible information processing capabilities for handling real-life ambiguous situations. Several research articles dealing with the application of soft computing tools to bioinformatics have been published in the recent past; however, they are scattered in different journals, conference proceedings and technical reports, thus causing inconvenience to readers, students and researchers.This book, unique in its nature, is aimed at providing a treatise in a unified framework, with both theoretical and experimental results, describing the basic principles of soft computing and demonstrating the various ways in which they can be used for analyzing biological data in an efficient manner. Interesting research articles from eminent scientists around the world are brought together in a systematic way such that the reader will be able to understand the issues and challenges in this domain, the existing ways of tackling them, recent trends, and future directions. This book is the first of its kind to bring together two important research areas, soft computing and bioinformatics, in order to demonstrate how the tools and techniques in the former can be used for efficiently solving several problems in the latter.
Soft Computing for Data Mining Applications
Author: K. R. Venugopal
Publisher: Springer
ISBN: 3642001939
Category : Computers
Languages : en
Pages : 354
Book Description
The authors have consolidated their research work in this volume titled Soft Computing for Data Mining Applications. The monograph gives an insight into the research in the ?elds of Data Mining in combination with Soft Computing methodologies. In these days, the data continues to grow - ponentially. Much of the data is implicitly or explicitly imprecise. Database discovery seeks to discover noteworthy, unrecognized associations between the data items in the existing database. The potential of discovery comes from the realization that alternate contexts may reveal additional valuable information. The rate at which the data is storedis growing at a phenomenal rate. Asaresult,traditionaladhocmixturesofstatisticaltechniquesanddata managementtools are no longer adequate for analyzing this vast collection of data. Severaldomainswherelargevolumesofdataarestoredincentralizedor distributeddatabasesincludesapplicationslikeinelectroniccommerce,bio- formatics, computer security, Web intelligence, intelligent learning database systems,?nance,marketing,healthcare,telecommunications,andother?elds. E?cient tools and algorithms for knowledge discovery in large data sets have been devised during the recent years. These methods exploit the ca- bility of computers to search huge amounts of data in a fast and e?ective manner. However,the data to be analyzed is imprecise and a?icted with - certainty. In the case of heterogeneous data sources such as text and video, the data might moreover be ambiguous and partly con?icting. Besides, p- terns and relationships of interest are usually approximate. Thus, in order to make the information mining process more robust it requires tolerance toward imprecision, uncertainty and exceptions.
Publisher: Springer
ISBN: 3642001939
Category : Computers
Languages : en
Pages : 354
Book Description
The authors have consolidated their research work in this volume titled Soft Computing for Data Mining Applications. The monograph gives an insight into the research in the ?elds of Data Mining in combination with Soft Computing methodologies. In these days, the data continues to grow - ponentially. Much of the data is implicitly or explicitly imprecise. Database discovery seeks to discover noteworthy, unrecognized associations between the data items in the existing database. The potential of discovery comes from the realization that alternate contexts may reveal additional valuable information. The rate at which the data is storedis growing at a phenomenal rate. Asaresult,traditionaladhocmixturesofstatisticaltechniquesanddata managementtools are no longer adequate for analyzing this vast collection of data. Severaldomainswherelargevolumesofdataarestoredincentralizedor distributeddatabasesincludesapplicationslikeinelectroniccommerce,bio- formatics, computer security, Web intelligence, intelligent learning database systems,?nance,marketing,healthcare,telecommunications,andother?elds. E?cient tools and algorithms for knowledge discovery in large data sets have been devised during the recent years. These methods exploit the ca- bility of computers to search huge amounts of data in a fast and e?ective manner. However,the data to be analyzed is imprecise and a?icted with - certainty. In the case of heterogeneous data sources such as text and video, the data might moreover be ambiguous and partly con?icting. Besides, p- terns and relationships of interest are usually approximate. Thus, in order to make the information mining process more robust it requires tolerance toward imprecision, uncertainty and exceptions.
Advanced Soft Computing Techniques in Data Science, IoT and Cloud Computing
Author: Sujata Dash
Publisher: Springer Nature
ISBN: 3030756572
Category : Technology & Engineering
Languages : en
Pages : 443
Book Description
This book plays a significant role in improvising human life to a great extent. The new applications of soft computing can be regarded as an emerging field in computer science, automatic control engineering, medicine, biology application, natural environmental engineering, and pattern recognition. Now, the exemplar model for soft computing is human brain. The use of various techniques of soft computing is nowadays successfully implemented in many domestic, commercial, and industrial applications due to the low-cost and very high-performance digital processors and also the decline price of the memory chips. This is the main reason behind the wider expansion of soft computing techniques and its application areas. These computing methods also play a significant role in the design and optimization in diverse engineering disciplines. With the influence and the development of the Internet of things (IoT) concept, the need for using soft computing techniques has become more significant than ever. In general, soft computing methods are closely similar to biological processes than traditional techniques, which are mostly based on formal logical systems, such as sentential logic and predicate logic, or rely heavily on computer-aided numerical analysis. Soft computing techniques are anticipated to complement each other. The aim of these techniques is to accept imprecision, uncertainties, and approximations to get a rapid solution. However, recent advancements in representation soft computing algorithms (fuzzy logic,evolutionary computation, machine learning, and probabilistic reasoning) generate a more intelligent and robust system providing a human interpretable, low-cost, approximate solution. Soft computing-based algorithms have demonstrated great performance to a variety of areas including multimedia retrieval, fault tolerance, system modelling, network architecture, Web semantics, big data analytics, time series, biomedical and health informatics, etc. Soft computing approaches such as genetic programming (GP), support vector machine–firefly algorithm (SVM-FFA), artificial neural network (ANN), and support vector machine–wavelet (SVM–Wavelet) have emerged as powerful computational models. These have also shown significant success in dealing with massive data analysis for large number of applications. All the researchers and practitioners will be highly benefited those who are working in field of computer engineering, medicine, biology application, signal processing, and mechanical engineering. This book is a good collection of state-of-the-art approaches for soft computing-based applications to various engineering fields. It is very beneficial for the new researchers and practitioners working in the field to quickly know the best performing methods. They would be able to compare different approaches and can carry forward their research in the most important area of research which has direct impact on betterment of the human life and health. This book is very useful because there is no book in the market which provides a good collection of state-of-the-art methods of soft computing-based models for multimedia retrieval, fault tolerance, system modelling, network architecture, Web semantics, big data analytics, time series, and biomedical and health informatics.
Publisher: Springer Nature
ISBN: 3030756572
Category : Technology & Engineering
Languages : en
Pages : 443
Book Description
This book plays a significant role in improvising human life to a great extent. The new applications of soft computing can be regarded as an emerging field in computer science, automatic control engineering, medicine, biology application, natural environmental engineering, and pattern recognition. Now, the exemplar model for soft computing is human brain. The use of various techniques of soft computing is nowadays successfully implemented in many domestic, commercial, and industrial applications due to the low-cost and very high-performance digital processors and also the decline price of the memory chips. This is the main reason behind the wider expansion of soft computing techniques and its application areas. These computing methods also play a significant role in the design and optimization in diverse engineering disciplines. With the influence and the development of the Internet of things (IoT) concept, the need for using soft computing techniques has become more significant than ever. In general, soft computing methods are closely similar to biological processes than traditional techniques, which are mostly based on formal logical systems, such as sentential logic and predicate logic, or rely heavily on computer-aided numerical analysis. Soft computing techniques are anticipated to complement each other. The aim of these techniques is to accept imprecision, uncertainties, and approximations to get a rapid solution. However, recent advancements in representation soft computing algorithms (fuzzy logic,evolutionary computation, machine learning, and probabilistic reasoning) generate a more intelligent and robust system providing a human interpretable, low-cost, approximate solution. Soft computing-based algorithms have demonstrated great performance to a variety of areas including multimedia retrieval, fault tolerance, system modelling, network architecture, Web semantics, big data analytics, time series, biomedical and health informatics, etc. Soft computing approaches such as genetic programming (GP), support vector machine–firefly algorithm (SVM-FFA), artificial neural network (ANN), and support vector machine–wavelet (SVM–Wavelet) have emerged as powerful computational models. These have also shown significant success in dealing with massive data analysis for large number of applications. All the researchers and practitioners will be highly benefited those who are working in field of computer engineering, medicine, biology application, signal processing, and mechanical engineering. This book is a good collection of state-of-the-art approaches for soft computing-based applications to various engineering fields. It is very beneficial for the new researchers and practitioners working in the field to quickly know the best performing methods. They would be able to compare different approaches and can carry forward their research in the most important area of research which has direct impact on betterment of the human life and health. This book is very useful because there is no book in the market which provides a good collection of state-of-the-art methods of soft computing-based models for multimedia retrieval, fault tolerance, system modelling, network architecture, Web semantics, big data analytics, time series, and biomedical and health informatics.
Proceedings of the Second International Conference on Soft Computing for Problem Solving (SocProS 2012), December 28-30, 2012
Author: B. V. Babu
Publisher: Springer
ISBN: 8132216024
Category : Technology & Engineering
Languages : en
Pages : 1529
Book Description
The present book is based on the research papers presented in the International Conference on Soft Computing for Problem Solving (SocProS 2012), held at JK Lakshmipat University, Jaipur, India. This book provides the latest developments in the area of soft computing and covers a variety of topics, including mathematical modeling, image processing, optimization, swarm intelligence, evolutionary algorithms, fuzzy logic, neural networks, forecasting, data mining, etc. The objective of the book is to familiarize the reader with the latest scientific developments that are taking place in various fields and the latest sophisticated problem solving tools that are being developed to deal with the complex and intricate problems that are otherwise difficult to solve by the usual and traditional methods. The book is directed to the researchers and scientists engaged in various fields of Science and Technology.
Publisher: Springer
ISBN: 8132216024
Category : Technology & Engineering
Languages : en
Pages : 1529
Book Description
The present book is based on the research papers presented in the International Conference on Soft Computing for Problem Solving (SocProS 2012), held at JK Lakshmipat University, Jaipur, India. This book provides the latest developments in the area of soft computing and covers a variety of topics, including mathematical modeling, image processing, optimization, swarm intelligence, evolutionary algorithms, fuzzy logic, neural networks, forecasting, data mining, etc. The objective of the book is to familiarize the reader with the latest scientific developments that are taking place in various fields and the latest sophisticated problem solving tools that are being developed to deal with the complex and intricate problems that are otherwise difficult to solve by the usual and traditional methods. The book is directed to the researchers and scientists engaged in various fields of Science and Technology.
Soft Computing Approach to Pattern Recognition and Image Processing
Author: Ashish Ghosh
Publisher: World Scientific
ISBN: 9789812776235
Category : Computers
Languages : en
Pages : 374
Book Description
This volume provides a collection of sixteen articles containing review and new material. In a unified way, they describe the recent development of theories and methodologies in pattern recognition, image processing and vision using fuzzy logic, artificial neural networks, genetic algorithms, rough sets and wavelets with significant real life applications. The book details the theory of granular computing and the role of a rough-neuro approach as a way of computing with words and designing intelligent recognition systems. It also demonstrates applications of the soft computing paradigm to case based reasoning, data mining and bio-informatics with a scope for future research. The contributors from around the world present a balanced mixture of current theory, algorithms and applications, making the book an extremely useful resource for students and researchers alike. Contents: Pattern Recognition: Multiple Classifier Systems; Building Decision Trees from the Fourier Spectrum of a Tree Ensemble; Clustering Large Data Sets; Multi-objective Variable String Genetic Classifier: Application to Remote Sensing Imagery; Image Processing and Vision: Dissimilarity Measures Between Fuzzy Sets or Fuzzy Structures; Early Vision: Concepts and Algorithms; Self-organizing Neural Network for Multi-level Image Segmentation; Geometric Transformation by Moment Method with Wavelet Matrix; New Computationally Efficient Algorithms for Video Coding; Soft Computing for Computational Media Aesthetics: Analyzing Video Content for Meaning; Granular Computing and Case Based Reasoning: Towards Granular Multi-agent Systems; Granular Computing and Pattern Recognition; Case Base Maintenance: A Soft Computing Perspective; Real Life Applications: Autoassociative Neural Network Models for Pattern Recognition Tasks in Speech and Image; Protein Structure Prediction Using Soft Computing; Pattern Classification for Biological Data Mining. Readership: Upper level undergraduates, graduates, researchers, academics and industrialists.
Publisher: World Scientific
ISBN: 9789812776235
Category : Computers
Languages : en
Pages : 374
Book Description
This volume provides a collection of sixteen articles containing review and new material. In a unified way, they describe the recent development of theories and methodologies in pattern recognition, image processing and vision using fuzzy logic, artificial neural networks, genetic algorithms, rough sets and wavelets with significant real life applications. The book details the theory of granular computing and the role of a rough-neuro approach as a way of computing with words and designing intelligent recognition systems. It also demonstrates applications of the soft computing paradigm to case based reasoning, data mining and bio-informatics with a scope for future research. The contributors from around the world present a balanced mixture of current theory, algorithms and applications, making the book an extremely useful resource for students and researchers alike. Contents: Pattern Recognition: Multiple Classifier Systems; Building Decision Trees from the Fourier Spectrum of a Tree Ensemble; Clustering Large Data Sets; Multi-objective Variable String Genetic Classifier: Application to Remote Sensing Imagery; Image Processing and Vision: Dissimilarity Measures Between Fuzzy Sets or Fuzzy Structures; Early Vision: Concepts and Algorithms; Self-organizing Neural Network for Multi-level Image Segmentation; Geometric Transformation by Moment Method with Wavelet Matrix; New Computationally Efficient Algorithms for Video Coding; Soft Computing for Computational Media Aesthetics: Analyzing Video Content for Meaning; Granular Computing and Case Based Reasoning: Towards Granular Multi-agent Systems; Granular Computing and Pattern Recognition; Case Base Maintenance: A Soft Computing Perspective; Real Life Applications: Autoassociative Neural Network Models for Pattern Recognition Tasks in Speech and Image; Protein Structure Prediction Using Soft Computing; Pattern Classification for Biological Data Mining. Readership: Upper level undergraduates, graduates, researchers, academics and industrialists.
Soft Computing Approach Pattern Recognition And Image Processing
Author: Ashish Ghosh
Publisher: World Scientific
ISBN: 981448685X
Category : Computers
Languages : en
Pages : 371
Book Description
This volume provides a collection of sixteen articles containing review and new material. In a unified way, they describe the recent development of theories and methodologies in pattern recognition, image processing and vision using fuzzy logic, artificial neural networks, genetic algorithms, rough sets and wavelets with significant real life applications.The book details the theory of granular computing and the role of a rough-neuro approach as a way of computing with words and designing intelligent recognition systems. It also demonstrates applications of the soft computing paradigm to case based reasoning, data mining and bio-informatics with a scope for future research.The contributors from around the world present a balanced mixture of current theory, algorithms and applications, making the book an extremely useful resource for students and researchers alike.
Publisher: World Scientific
ISBN: 981448685X
Category : Computers
Languages : en
Pages : 371
Book Description
This volume provides a collection of sixteen articles containing review and new material. In a unified way, they describe the recent development of theories and methodologies in pattern recognition, image processing and vision using fuzzy logic, artificial neural networks, genetic algorithms, rough sets and wavelets with significant real life applications.The book details the theory of granular computing and the role of a rough-neuro approach as a way of computing with words and designing intelligent recognition systems. It also demonstrates applications of the soft computing paradigm to case based reasoning, data mining and bio-informatics with a scope for future research.The contributors from around the world present a balanced mixture of current theory, algorithms and applications, making the book an extremely useful resource for students and researchers alike.
Proceedings of Seventh International Conference on Bio-Inspired Computing: Theories and Applications (BIC-TA 2012)
Author: Jagdish C. Bansal
Publisher: Springer Science & Business Media
ISBN: 8132210387
Category : Technology & Engineering
Languages : en
Pages : 559
Book Description
The book is a collection of high quality peer reviewed research papers presented in Seventh International Conference on Bio-Inspired Computing (BIC-TA 2012) held at ABV-IIITM Gwalior, India. These research papers provide the latest developments in the broad area of "Computational Intelligence". The book discusses wide variety of industrial, engineering and scientific applications of nature/bio-inspired computing and presents invited papers from the inventors/originators of novel computational techniques.
Publisher: Springer Science & Business Media
ISBN: 8132210387
Category : Technology & Engineering
Languages : en
Pages : 559
Book Description
The book is a collection of high quality peer reviewed research papers presented in Seventh International Conference on Bio-Inspired Computing (BIC-TA 2012) held at ABV-IIITM Gwalior, India. These research papers provide the latest developments in the broad area of "Computational Intelligence". The book discusses wide variety of industrial, engineering and scientific applications of nature/bio-inspired computing and presents invited papers from the inventors/originators of novel computational techniques.
Proceedings of the International Conference on Information Systems Design and Intelligent Applications 2012 (India 2012) held in Visakhapatnam, India, January 2012
Author: Suresh Chandra Satapathy
Publisher: Springer Science & Business Media
ISBN: 3642274439
Category : Technology & Engineering
Languages : en
Pages : 948
Book Description
This volume contains the papers presented at INDIA-2012: International conference on Information system Design and Intelligent Applications held on January 5-7, 2012 in Vishakhapatnam, India. This conference was organized by Computer Society of India (CSI), Vishakhapatnam chapter well supported by Vishakhapatnam Steel, RINL, Govt of India. It contains 108 papers contributed by authors from six different countries across four continents. These research papers mainly focused on intelligent applications and various system design issues. The papers cover a wide range of topics of computer science and information technology discipline ranging from image processing, data base application, data mining, grid and cloud computing, bioinformatics among many others. The various intelligent tools like swarm intelligence, artificial intelligence, evolutionary algorithms, bio-inspired algorithms have been applied in different papers for solving various challenging IT related problems.
Publisher: Springer Science & Business Media
ISBN: 3642274439
Category : Technology & Engineering
Languages : en
Pages : 948
Book Description
This volume contains the papers presented at INDIA-2012: International conference on Information system Design and Intelligent Applications held on January 5-7, 2012 in Vishakhapatnam, India. This conference was organized by Computer Society of India (CSI), Vishakhapatnam chapter well supported by Vishakhapatnam Steel, RINL, Govt of India. It contains 108 papers contributed by authors from six different countries across four continents. These research papers mainly focused on intelligent applications and various system design issues. The papers cover a wide range of topics of computer science and information technology discipline ranging from image processing, data base application, data mining, grid and cloud computing, bioinformatics among many others. The various intelligent tools like swarm intelligence, artificial intelligence, evolutionary algorithms, bio-inspired algorithms have been applied in different papers for solving various challenging IT related problems.
Biotechnology: Concepts, Methodologies, Tools, and Applications
Author: Management Association, Information Resources
Publisher: IGI Global
ISBN: 152258904X
Category : Science
Languages : en
Pages : 2220
Book Description
Biotechnology can be defined as the manipulation of biological process, systems, and organisms in the production of various products. With applications in a number of fields such as biomedical, chemical, mechanical, and civil engineering, research on the development of biologically inspired materials is essential to further advancement. Biotechnology: Concepts, Methodologies, Tools, and Applications is a vital reference source for the latest research findings on the application of biotechnology in medicine, engineering, agriculture, food production, and other areas. It also examines the economic impacts of biotechnology use. Highlighting a range of topics such as pharmacogenomics, biomedical engineering, and bioinformatics, this multi-volume book is ideally designed for engineers, pharmacists, medical professionals, practitioners, academicians, and researchers interested in the applications of biotechnology.
Publisher: IGI Global
ISBN: 152258904X
Category : Science
Languages : en
Pages : 2220
Book Description
Biotechnology can be defined as the manipulation of biological process, systems, and organisms in the production of various products. With applications in a number of fields such as biomedical, chemical, mechanical, and civil engineering, research on the development of biologically inspired materials is essential to further advancement. Biotechnology: Concepts, Methodologies, Tools, and Applications is a vital reference source for the latest research findings on the application of biotechnology in medicine, engineering, agriculture, food production, and other areas. It also examines the economic impacts of biotechnology use. Highlighting a range of topics such as pharmacogenomics, biomedical engineering, and bioinformatics, this multi-volume book is ideally designed for engineers, pharmacists, medical professionals, practitioners, academicians, and researchers interested in the applications of biotechnology.
Introduction to Protein Structure Prediction
Author: Huzefa Rangwala
Publisher: John Wiley & Sons
ISBN: 111809946X
Category : Science
Languages : en
Pages : 611
Book Description
A look at the methods and algorithms used to predict protein structure A thorough knowledge of the function and structure of proteins is critical for the advancement of biology and the life sciences as well as the development of better drugs, higher-yield crops, and even synthetic bio-fuels. To that end, this reference sheds light on the methods used for protein structure prediction and reveals the key applications of modeled structures. This indispensable book covers the applications of modeled protein structures and unravels the relationship between pure sequence information and three-dimensional structure, which continues to be one of the greatest challenges in molecular biology. With this resource, readers will find an all-encompassing examination of the problems, methods, tools, servers, databases, and applications of protein structure prediction and they will acquire unique insight into the future applications of the modeled protein structures. The book begins with a thorough introduction to the protein structure prediction problem and is divided into four themes: a background on structure prediction, the prediction of structural elements, tertiary structure prediction, and functional insights. Within those four sections, the following topics are covered: Databases and resources that are commonly used for protein structure prediction The structure prediction flagship assessment (CASP) and the protein structure initiative (PSI) Definitions of recurring substructures and the computational approaches used for solving sequence problems Difficulties with contact map prediction and how sophisticated machine learning methods can solve those problems Structure prediction methods that rely on homology modeling, threading, and fragment assembly Hybrid methods that achieve high-resolution protein structures Parts of the protein structure that may be conserved and used to interact with other biomolecules How the loop prediction problem can be used for refinement of the modeled structures The computational model that detects the differences between protein structure and its modeled mutant Whether working in the field of bioinformatics or molecular biology research or taking courses in protein modeling, readers will find the content in this book invaluable.
Publisher: John Wiley & Sons
ISBN: 111809946X
Category : Science
Languages : en
Pages : 611
Book Description
A look at the methods and algorithms used to predict protein structure A thorough knowledge of the function and structure of proteins is critical for the advancement of biology and the life sciences as well as the development of better drugs, higher-yield crops, and even synthetic bio-fuels. To that end, this reference sheds light on the methods used for protein structure prediction and reveals the key applications of modeled structures. This indispensable book covers the applications of modeled protein structures and unravels the relationship between pure sequence information and three-dimensional structure, which continues to be one of the greatest challenges in molecular biology. With this resource, readers will find an all-encompassing examination of the problems, methods, tools, servers, databases, and applications of protein structure prediction and they will acquire unique insight into the future applications of the modeled protein structures. The book begins with a thorough introduction to the protein structure prediction problem and is divided into four themes: a background on structure prediction, the prediction of structural elements, tertiary structure prediction, and functional insights. Within those four sections, the following topics are covered: Databases and resources that are commonly used for protein structure prediction The structure prediction flagship assessment (CASP) and the protein structure initiative (PSI) Definitions of recurring substructures and the computational approaches used for solving sequence problems Difficulties with contact map prediction and how sophisticated machine learning methods can solve those problems Structure prediction methods that rely on homology modeling, threading, and fragment assembly Hybrid methods that achieve high-resolution protein structures Parts of the protein structure that may be conserved and used to interact with other biomolecules How the loop prediction problem can be used for refinement of the modeled structures The computational model that detects the differences between protein structure and its modeled mutant Whether working in the field of bioinformatics or molecular biology research or taking courses in protein modeling, readers will find the content in this book invaluable.