Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 614
Book Description
Analysis of a Gene Amplification Event in Rat Cells
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 614
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 614
Book Description
Gene Amplification in Mammalian Cells
Author: Rodney E. Kellems
Publisher: CRC Press
ISBN: 1000148092
Category : Science
Languages : en
Pages : 584
Book Description
Serves as a comprehensive review to the substantial impact of gene amplification in molecular biology, genetic engineering and medical science. The book covers the mechanism of gene amplification, organization and structure of amplified genes.
Publisher: CRC Press
ISBN: 1000148092
Category : Science
Languages : en
Pages : 584
Book Description
Serves as a comprehensive review to the substantial impact of gene amplification in molecular biology, genetic engineering and medical science. The book covers the mechanism of gene amplification, organization and structure of amplified genes.
The Leydig Cell
Author: Anita H. Payne
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 882
Book Description
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 882
Book Description
Genomic Disorders
Author: James R. Lupski
Publisher: Springer Science & Business Media
ISBN: 1597450391
Category : Medical
Languages : en
Pages : 419
Book Description
A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated with disease. Technologies to assay for such structural variation of the human genome and to model genomic disorders in mice are also presented. Two appendices detail the genomic disorders, providing genomic features at the locus undergoing rearrangement, their clinical features, and frequency of detection.
Publisher: Springer Science & Business Media
ISBN: 1597450391
Category : Medical
Languages : en
Pages : 419
Book Description
A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated with disease. Technologies to assay for such structural variation of the human genome and to model genomic disorders in mice are also presented. Two appendices detail the genomic disorders, providing genomic features at the locus undergoing rearrangement, their clinical features, and frequency of detection.
Systems Biology of Cancer
Author: Sam Thiagalingam
Publisher: Cambridge University Press
ISBN: 0521493390
Category : Mathematics
Languages : en
Pages : 597
Book Description
An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.
Publisher: Cambridge University Press
ISBN: 0521493390
Category : Mathematics
Languages : en
Pages : 597
Book Description
An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.
Research Awards Index
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 776
Book Description
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 776
Book Description
Memorial Candles: Children of the Holocaust
Author: Dina Wardi
Publisher: Routledge
ISBN: 1317799550
Category : Psychology
Languages : en
Pages : 283
Book Description
As the children of the Holocaust reach adulthood, they often need professional help in establishing a new identity and self-esteem. During their childhood their parents have unconsciously transmitted to them much of their own trauma, investing them with all their memories and hopes, so that they become 'memorial candles' to those who did not survive. The book combines verbatim transcriptions of dialogues in individual and group psychotherapy sessions with analyses of dreams, fantasies and childhood memories. Diana Wardi traces the emotional history of her patients, accompanying them on a painful and moving journey into their inner world. She describes the children's infancy in the guilt-laden atmosphere of survivor families, through to their difficult separation from their parents in maturity. she also traces in detail the therapeutic process which culminates in the patients' separation from the role of 'memorial candle'.
Publisher: Routledge
ISBN: 1317799550
Category : Psychology
Languages : en
Pages : 283
Book Description
As the children of the Holocaust reach adulthood, they often need professional help in establishing a new identity and self-esteem. During their childhood their parents have unconsciously transmitted to them much of their own trauma, investing them with all their memories and hopes, so that they become 'memorial candles' to those who did not survive. The book combines verbatim transcriptions of dialogues in individual and group psychotherapy sessions with analyses of dreams, fantasies and childhood memories. Diana Wardi traces the emotional history of her patients, accompanying them on a painful and moving journey into their inner world. She describes the children's infancy in the guilt-laden atmosphere of survivor families, through to their difficult separation from their parents in maturity. she also traces in detail the therapeutic process which culminates in the patients' separation from the role of 'memorial candle'.
Gene Quantification
Author: Francois Ferre
Publisher: Springer Science & Business Media
ISBN: 1461241642
Category : Medical
Languages : en
Pages : 379
Book Description
Geneticists and molecular biologists have been interested in quantifying genes and their products for many years and for various reasons (Bishop, 1974). Early molecular methods were based on molecular hybridization, and were devised shortly after Marmur and Doty (1961) first showed that denaturation of the double helix could be reversed - that the process of molecular reassociation was exquisitely sequence dependent. Gillespie and Spiegelman (1965) developed a way of using the method to titrate the number of copies of a probe within a target sequence in which the target sequence was fixed to a membrane support prior to hybridization with the probe - typically a RNA. Thus, this was a precursor to many of the methods still in use, and indeed under development, today. Early examples of the application of these methods included the measurement of the copy numbers in gene families such as the ribosomal genes and the immunoglo bulin family. Amplification of genes in tumors and in response to drug treatment was discovered by this method. In the same period, methods were invented for estimating gene num bers based on the kinetics of the reassociation process - the so-called Cot analysis. This method, which exploits the dependence of the rate of reassociation on the concentration of the two strands, revealed the presence of repeated sequences in the DNA of higher eukaryotes (Britten and Kohne, 1968). An adaptation to RNA, Rot analysis (Melli and Bishop, 1969), was used to measure the abundance of RNAs in a mixed population.
Publisher: Springer Science & Business Media
ISBN: 1461241642
Category : Medical
Languages : en
Pages : 379
Book Description
Geneticists and molecular biologists have been interested in quantifying genes and their products for many years and for various reasons (Bishop, 1974). Early molecular methods were based on molecular hybridization, and were devised shortly after Marmur and Doty (1961) first showed that denaturation of the double helix could be reversed - that the process of molecular reassociation was exquisitely sequence dependent. Gillespie and Spiegelman (1965) developed a way of using the method to titrate the number of copies of a probe within a target sequence in which the target sequence was fixed to a membrane support prior to hybridization with the probe - typically a RNA. Thus, this was a precursor to many of the methods still in use, and indeed under development, today. Early examples of the application of these methods included the measurement of the copy numbers in gene families such as the ribosomal genes and the immunoglo bulin family. Amplification of genes in tumors and in response to drug treatment was discovered by this method. In the same period, methods were invented for estimating gene num bers based on the kinetics of the reassociation process - the so-called Cot analysis. This method, which exploits the dependence of the rate of reassociation on the concentration of the two strands, revealed the presence of repeated sequences in the DNA of higher eukaryotes (Britten and Kohne, 1968). An adaptation to RNA, Rot analysis (Melli and Bishop, 1969), was used to measure the abundance of RNAs in a mixed population.
Biomedical Index to PHS-supported Research
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1060
Book Description
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1060
Book Description
Subject Index of Current Extramural Research Administered by the National Cancer Institute
Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 714
Book Description
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 714
Book Description