An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2

An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2 PDF Author: Joachim Jose
Publisher: MDPI
ISBN: 3038424129
Category : Medical
Languages : en
Pages : 321

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Book Description
This book is a printed edition of the Special Issue "An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2" that was published in Pharmaceuticals

An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2

An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2 PDF Author: Joachim Jose
Publisher: MDPI
ISBN: 3038424129
Category : Medical
Languages : en
Pages : 321

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Book Description
This book is a printed edition of the Special Issue "An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2" that was published in Pharmaceuticals

An Updated View on an Emerging Target

An Updated View on an Emerging Target PDF Author:
Publisher:
ISBN: 9783038424130
Category : Electronic book
Languages : en
Pages :

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Book Description


Overcoming Data Scarcity in Earth Science

Overcoming Data Scarcity in Earth Science PDF Author: Angela Gorgoglione
Publisher: MDPI
ISBN: 3039282107
Category : Science
Languages : en
Pages : 94

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Book Description
heavily Environmental mathematical models represent one of the key aids for scientists to forecast, create, and evaluate complex scenarios. These models rely on the data collected by direct field observations. However, assembly of a functional and comprehensive dataset for any environmental variable is difficult, mainly because of i) the high cost of the monitoring campaigns and ii) the low reliability of measurements (e.g., due to occurrences of equipment malfunctions and/or issues related to equipment location). The lack of a sufficient amount of Earth science data may induce an inadequate representation of the response’s complexity in any environmental system to any type of input/change, both natural and human-induced. In such a case, before undertaking expensive studies to gather and analyze additional data, it is reasonable to first understand what enhancement in estimates of system performance would result if all the available data could be well exploited. Missing data imputation is an important task in cases where it is crucial to use all available data and not discard records with missing values. Different approaches are available to deal with missing data. Traditional statistical data completion methods are used in different domains to deal with single and multiple imputation problems. More recently, machine learning techniques, such as clustering and classification, have been proposed to complete missing data. This book showcases the body of knowledge that is aimed at improving the capacity to exploit the available data to better represent, understand, predict, and manage the behavior of environmental systems at all practical scales.

The Epithelial-to-Mesenchymal Transition (EMT) in Cancer

The Epithelial-to-Mesenchymal Transition (EMT) in Cancer PDF Author: Joëlle Roche
Publisher: MDPI
ISBN: 3038427934
Category : Science
Languages : en
Pages : 261

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Book Description
This book is a printed edition of the Special Issue "The Epithelial-to-Mesenchymal Transition (EMT) in Cancer" that was published in Cancers

Concepts and Principles of Pharmacology

Concepts and Principles of Pharmacology PDF Author: James E. Barrett
Publisher: Springer Nature
ISBN: 3030353621
Category : Medical
Languages : en
Pages : 466

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Book Description
Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.

Protein Phosphorylation in Human Health

Protein Phosphorylation in Human Health PDF Author: Cai Huang
Publisher: BoD – Books on Demand
ISBN: 9535107372
Category : Medical
Languages : en
Pages : 482

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Book Description
15 chapters on protein phosphorylation and human health written by expert scientists. Covers most important research hot points, such as Akt, AMPK and mTOR. Bridges the basic protein phosphorylation pathways with human health and diseases. Detailed and comprehensive text with excellent figure illustration.

World Malaria Report 2019

World Malaria Report 2019 PDF Author: World Health Organization
Publisher:
ISBN: 9789241565721
Category :
Languages : en
Pages : 224

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Book Description
The World Malaria Report 2019 provides a comprehensive update on global and regional malaria data and trends. The report tracks investments in malaria programs and research as well as progress across all intervention areas: prevention, diagnosis, treatment, elimination, and surveillance. It also includes dedicated chapters on the consequences of malaria on maternal infant and child health the "High Burden to High Impact" approach as well as biological threats to the fight against malaria. The 2019 report is based on information received from more than 80 countries and areas with ongoing malaria transmission. This information is supplemented by data from national household surveys and databases held by other organizations.

Advances in Nutrition and Cancer 2

Advances in Nutrition and Cancer 2 PDF Author: Vincenzo Zappia
Publisher: Springer Science & Business Media
ISBN: 1475732309
Category : Medical
Languages : en
Pages : 313

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Book Description
This volume includes contributions presented at the Second International Sym posium on Nutrition and Cancer, held in Naples, Italy, in October 1998 at the National Tumor Institute "Fondazione Pascale." During the Conference, experts from different disciplines discussed pivotal and timely subjects on the interactions between human nutrition and the development of malignancies. Comparing the themes of this Meeting with those discussed at the First Sympo sium in 1992, the major scientific advancements certainly derive from the extensive use of molecular approaches to perform research in nutrition. Moreover, the fundamental observation of R. Doll and R. Peto (1981), which suggested that at least 35% of all cancers (with large differences among different tumors) might be prevented by dietary regimens, has been definitively confirmed by epidemiological studies. On the other hand, the relationships between diet and cancer are quite intricate and complex; it is difficult, and at the same time not methodologically correct, to reduce them to simple terms. Metabolic and hormonal factors, contaminants and biological agents, and deficiency of specific protective nutrients are all pieces of the same puzzle.

The Impact of Tumor Biology on Cancer Treatment and Multidisciplinary Strategies

The Impact of Tumor Biology on Cancer Treatment and Multidisciplinary Strategies PDF Author: Michael Molls
Publisher: Springer Science & Business Media
ISBN: 3540743863
Category : Medical
Languages : en
Pages : 363

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Book Description
Te rapidly changing concepts in radiation oncology with the development of more precise - strumentation for delivery of radiation therapy and a greater emphasis on hypofractionation technologies require a very intimate knowledge of tumor biology and the infuence of various biologic factors on dose distribution within the tumor in terms of homogeneity as well as prev- tion of any late efects on normal tissue surrounding the tumor itself. Not only are these major factors in clinical practice but also the known factors of inhomogeneity of cancer cells, the impact of microenvironment in terms of radiation efect, and host factors make it mandatory to design therapeutic strategies to improve the outcome and to diminish any potential short-term or lo- term risks from the radiation therapy. Te authors have developed an outstanding text that deals with these strategies and how they would impact on established and emerging new technologies and treatment. Te context of the presentations within a multidisciplinary combined modality therapy program is incredibly - portant. In this volume, various topics are reviewed including tumor genesis, cell proliferation, - giogenesis, the physiologic characteristics of malignant tissues, invasion and adhesion, the route and role pursued in the development of metastasis, and the role of the human immune system in cancer prevention and development.

Antioxidants in Health and Disease

Antioxidants in Health and Disease PDF Author: Antonis Zampelas
Publisher: CRC Press
ISBN: 1466580119
Category : Medical
Languages : en
Pages : 340

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Book Description
Antioxidant use in health promotion and disease prevention either through dietary intake or supplementation is controversial. This book reviews the latest evidence-based research in the area, principally through prospective cohort studies and randomized controlled trials. It assesses major dietary antioxidants and discusses their use in diseases such as cancer, diabetes, stroke, coronary heart disease, HIV/AIDS, and neurodegenerative and immune diseases. The use of antioxidants in health is also discussed along with common adverse effects associated with antioxidant use.