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Author: Arthur K. Cho
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 536
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Book Description
Much of recent amphetamine research has focused on action mechanisms which may represent a liability for abuse. The research further points to apparent psychopathological disorders induced or precipitated by such abuse. Understanding action mechanisms may aid investigations into the pathophysiology and treatment of these disorders. The overviews contained in this book, which cover myriad aspects of the chemistry, pharmacology, behavior, and toxicology of amphetamineand its analogs, can assist researchers by summarizing past findings and indicating new directions of study. Key Features * Presents advances in action mechanisms, toxicity, and psychopharmacology of amphetamine and its analogs * Examines amphetamine abuse in the United States and Japan * Reviews literature from the mid-1970s to the present
Author: Arthur K. Cho
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 536
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Book Description
Much of recent amphetamine research has focused on action mechanisms which may represent a liability for abuse. The research further points to apparent psychopathological disorders induced or precipitated by such abuse. Understanding action mechanisms may aid investigations into the pathophysiology and treatment of these disorders. The overviews contained in this book, which cover myriad aspects of the chemistry, pharmacology, behavior, and toxicology of amphetamineand its analogs, can assist researchers by summarizing past findings and indicating new directions of study. Key Features * Presents advances in action mechanisms, toxicity, and psychopharmacology of amphetamine and its analogs * Examines amphetamine abuse in the United States and Japan * Reviews literature from the mid-1970s to the present
Author: Andreas Büttner
Publisher: Springer Nature
ISBN: 3030605310
Category : Medical
Languages : en
Pages : 116
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Book Description
This book provides a comprehensive overview of the current state of knowledge concerning neuropathologies resulting from drug abuse. The first chapters offer readers detailed information on the neurobiological basics of drug abuse and the results of neuroimaging studies in drug abusers. The focus of the book is on neuropathological findings in drug abusers for the predominant substances, which include cannabis, opiates, cocaine, amphetamine, methamphetamine and a broad spectrum of designer drugs. These findings are supported by histological illustrations and discussed in connection with recent scientific publications. A chapter specifically addressing clinicians is also included, and highlights the implications for further therapy. The book is essential reading for neuropathologists, neurologists, neuroradiologists and psychiatrists, as well as other health professionals and scientists interested and engaged in the problem of drug abuse. Although a great deal of data has been derived from animal models and from human neuroimaging studies, little is known about the morphological effects of drug abuse on the human brain. In recent years, fundamental drug-induced effects on the cellular elements of the brain have been detected. These alterations might not only be the substrate of the neuroimaging data but might also have implications for clinical research and therapy. In addition, drug abuse may induce premature neurodegeneration.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 503
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Book Description
Author: Mary V. Solanto
Publisher: Oxford University Press, USA
ISBN: 9780195133714
Category : Medical
Languages : en
Pages : 434
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Book Description
Stimulant drugs are widely used in the treatment of ADHD in children and adults. Hundreds of studies over the past 60 years have demonstrated their effectiveness in improving attention span, increasing impulse control, and reducing hyperactivity and restlessness. Despite widespread interest in these compounds, however, their mechanisms of action in the central nervous system have remained poorly understood. Recent advances in the basic and clinical neurosciences now afford the possibility of elucidating these mechanisms. The current volume is the first to bring this expanding knowledge to bear on the central question of why and how stimulants exert their therapeutic effects. The result is a careful, comprehensive, and insightful integration of material by well-known scientists that significantly advances our understanding of stimulant effects and charts a course for future research. Part I presents a comprehensive description of the clinical features of ADHD and the clinical response to stimulants. Part II details the cortical and subcortical neuroanatomy and functional neurophysiology of dopamine and norepinephrine systems with respect to the regulation of attention, arousal, activity, and impulse control and the effects of stimulants on these systems. Part III is devoted to clinical research, including recent studies of neuroimaging, genetics, pharmacodynamic and pharmacokinetic properties of stimulants, effects on cognitive functions, neurophysiological effects in humans with and without ADHD and in non-human primates, and comparison of stimulants and non-stimulants in the treatment of ADHD. Part IV is a masterful synthesis that presents alternative models of stimulant drug action and generates key hypotheses for continued research. The volume will be of keen interest to researchers and clinicians in psychiatry, psychology, and neurology, neuroscientists studying stimulants, and those pursuing development of new drugs to treat ADHD.
Author: Leslie Iversen
Publisher: Springer Science & Business Media
ISBN: 1475705107
Category : Psychology
Languages : en
Pages : 484
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Book Description
Underlying the design of the Handbook of Psychopharmacology is a prejudice that the study of drug influences on the mind has advanced to a stage where basic research and clinical application truly mesh. These later volumes of the Handbook are structured according to this conception. In certain volumes, groups of drugs are treated as classes with chapters ranging from basic chemistry to clinical application. Other volumes are assembled around topic areas such as anxiety or affective disorders. Thus, besides chapters on individual drug classes, we have included essays addressing broad areas such as "The Limbic-Hypothalamic-Pituitary-Adrenal System and Human Be havior" and "Peptides and the Central Nervous System. " Surveying these diverse contributions, one comes away with a sentiment that, far from being an "applied" science borrowing from fundamental brain chemistry and physiology, psychopharmacology has instead provided basic researchers with the tools and conceptual approaches which now are advancing neurobiology to a central role in modern biology. Especially gratifying is the sense that, while contributing to an understanding of how the brain functions, psychopharmacology is a discipline whose fruits offer genuine help to the mentally ill with promises of escalating benefits in the future. L. L. 1. S. D. I. S. H. S. VII CONTENTS CHAPTER 1 Amphetamines: Structure-Activity Relationships J. H. BIEL and B. A. Bopp 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2: Effects of Biogenic Amines . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2. 1. Norepinephrine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2. 2. Dopamine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2. 3. Serotonin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 3. Central Stimulatory Effects . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 3. 1. Phenethylamine Derivatives. . . . . . . . . . . . . . . . . . . . . .
Author: HOBSON
Publisher: Birkhäuser
ISBN: 1489967710
Category : Science
Languages : en
Pages : 141
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Book Description
Author: Owen Bowden-Jones
Publisher: Cambridge University Press
ISBN: 1911623095
Category : Medical
Languages : en
Pages : 141
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Book Description
Emerging illicit drugs pose a significant clinical challenge. This handbook offers an engaging, concise guide to managing these challenges.
Author: Eric Wagner
Publisher: Elsevier
ISBN: 0080508774
Category : Psychology
Languages : en
Pages : 407
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Book Description
Innovations in Adolescent Substance Abuse Interventions focuses on developmentally appropriate approaches to the assessment, prevention, or treatment of substance use problems among adolescents. Organized into 16 chapters, this book begins with an assessment of adolescent substance use; theory, methods, and effectiveness of a drug abuse prevention approach; and problem behavior prevention programming for schools and community groups. Some chapters follow on the community-, family- and school-based interventions for adolescents with substance use problems. Other chapters explain psychopharmacological therapy; the assertive aftercare protocol for adolescent substance abusers; and twelve-step-based interventions for adolescents.
Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781719520
Category : Medical
Languages : en
Pages : 848
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Book Description
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Author: Carla Marienfeld
Publisher: Springer Nature
ISBN: 303033404X
Category : Medical
Languages : en
Pages : 376
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Book Description
This book serves as a tool for general psychiatrists, medical students, residents, and fellows looking for a clinically relevant and high-yield overview of addiction psychiatry in preparation for their board exams – or for everyday clinical practice. Written by expert educators in addiction psychiatry, the text is organized by substances misused and populations affected. This book serves as both a primary learning tool for those new to the field, as well as a reference for those working in addiction treatment. Each chapter begins with summaries of high yield clinical pearls, followed by general information including treatment, and then ends with accompanying board-style review questions. The scope includes understanding substances of misuse and substance use disorders (SUDs), how to evaluate, diagnose, and monitor SUDs, how to treat SUDs both pharmacologically and behaviorally, and critical information for specific populations of patients. Absolute Addiction Psychiatry for Clinical Practice and Review is an excellent resource for all medical students, residents, fellows, and professionals taking certification exams in addiction, including those in psychiatry, addiction medicine, emergency medicine, internal medicine, pain medicine, and others. The chapter "Laboratory Testing for Substance Use Disorders" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
