Advances in The Immunology of Host Defense Peptide: Mechanisms and Applications of Antimicrobial Functions and Beyond PDF Download
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Author: Mark Hulett
Publisher: Frontiers Media SA
ISBN: 2889666670
Category : Medical
Languages : en
Pages : 399
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Book Description
Author: Mark Hulett
Publisher: Frontiers Media SA
ISBN: 2889666670
Category : Medical
Languages : en
Pages : 399
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Book Description
Author: Deirdre A. Devine
Publisher: Cambridge University Press
ISBN: 9780521822206
Category : Medical
Languages : en
Pages : 416
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Book Description
Cationic antimicrobial peptides are multifunctional peptides of the innate immune system, which not only act directly against microorganisms, but also signal between early and late immune responses and modulate inflammatory reposnes. The significance of these host defence peptides in combating infection and in host-microbe homeostasis has become increasingly clear, through advances made by microbiologists, biochemists, biophysicists, immunologists, molecular biologists, and a range of medical and pharmaceutical researchers. This book, drawing together contributions from leading scientists, reviews significant recent advances in our knowledge of mammalian antimicrobial peptides. In addition to providing up-to-date overviews of their structure, expression and biology, their multiple activities and interactions with microbial populations as well as their potential application as novel therapeutic agents are summarized. Chapters describing developments using animal models and investigations of the roles of these host defence peptides in microbial infections are complemented by chapters addressing their mechanisms of action and of microbial resistance.
Author: Shymaa Enany
Publisher: BoD – Books on Demand
ISBN: 183969713X
Category : Medical
Languages : en
Pages : 168
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Book Description
Modern medicine is impossible without antibiotics, but global antibiotic usage has led to the development of increasing numbers of multi-drug resistant (MDR) bacteria. Thus, we still have problems with infectious disease treatment despite an arsenal of antibiotics. This has forced researchers to develop new drugs that will be effective against resistant bacteria. Some of these prospective molecules are antimicrobial peptides (AMPs), which are an important component of the innate immune system of various organisms in nature. Currently, more than 3,000 AMPs have been reported with different activities against different bacterial species including resistant phenotype bacteria. AMPs display remarkable structural and functional diversity that is not completely understood. As such, this book presents a comprehensive overview of AMPs and their mechanism of action against MDR bacteria.
Author: Jorge L. Alió Del Barrio
Publisher: Frontiers Media SA
ISBN: 2832505570
Category : Medical
Languages : en
Pages : 143
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Book Description
Author: Dan Hultmark
Publisher:
ISBN:
Category :
Languages : en
Pages : 100
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Book Description
Author: Andrew F. Rowley
Publisher: Oxford University Press
ISBN: 0198853750
Category : Medical
Languages : en
Pages : 657
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Book Description
This book assembles an international team of the leading specialists in the field to review the main diseases and pathologic manifestations of all the major invertebrate groups, whilst describing their emergence in contexts such as climate change and global food security.
Author: Neil M. O’Brien-Simpson
Publisher: Frontiers Media SA
ISBN: 2889454703
Category :
Languages : en
Pages : 137
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Book Description
In 2014, the World Health Organization (WHO) listed cancer as the second leading cause of death and highlighted antimicrobial resistance as “a key global health challenge” that may, in a worst case scenario, lead to an annual death toll of 10 million by 2050, which would exceed predicted cancer deaths by 20%. Novel promising therapeutic options to reduce morbidity and mortality of both infectious microbial diseases and cancer are being developed based on antimicrobial peptides (AMPs), i.e., evolutionary proven antibiotics that also possess anti-cancer activities. Intriguingly, AMPs and anti-cancer peptides (ACPs) rely typically on novel mechanisms and cellular targets not used by current antibiotics or chemotherapeutics. Initiated by presentations at the International Meeting of Antimicrobial Peptides in 2016 (IMAP 2016), hosted at Leipzig University, Germany, this book compiles the most recent strategies and promising lead compounds for treating multi- and pan-resistant microbes and chemo-resistant cancer cells in fourteen different chapters representing leading research groups from five different continents. In this respect, the book shall stimulate new avenues of thinking and strategies in tackling forthcoming antimicrobial and cancer resistance health threats with the hope that the scenarios recently reported by the WHO will never eventuate.
Author: Sotirios Koutsopoulos
Publisher: Woodhead Publishing
ISBN: 0081007426
Category : Technology & Engineering
Languages : en
Pages : 655
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Book Description
Peptide Applications in Biomedicine, Biotechnology and Bioengineering summarizes the current knowledge on peptide applications in biomedicine, biotechnology and bioengineering. After a general introduction to peptides, the book addresses the many applications of peptides in biomedicine and medical technology. Next, the text focuses on peptide applications in biotechnology and bioengineering and reviews of peptide applications in nanotechnology. This book is a valuable resource for biomaterial scientists, polymer scientists, bioengineers, mechanical engineers, synthetic chemists, medical doctors and biologists. - Presents a self-contained work for the field of biomedical peptides - Summarizes the current knowledge on peptides in biomedicine, biotechnology and bioengineering - Covers current and potential applications of biomedical peptides
Author: Muthupandian Saravanan
Publisher: Elsevier
ISBN: 0323998100
Category : Technology & Engineering
Languages : en
Pages : 790
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Book Description
Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance focuses on recent and emerging trends surrounding nanomaterials and nano-drug delivery approaches to combat antimicrobial resistance. The relationship between nanomaterials and antimicrobial activity needs to be deeply explored to meet the challenges of combating antimicrobial resistance. The content of this book is divided into three main topic areas, including (i) how to overcome the existing traditional approaches to combat antimicrobial resistance, (ii) applying multiple drug delivery mechanisms to target multi-drug resistant microbes, and (iii) how nanomaterials can be used as drug carriers. This is an important reference source for those looking to understand how nanotechnology plays an important role in combatting disease and infection. As antimicrobial resistance threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses, and fungi, this is a timely resource. - Outlines how to overcome existing traditional approaches to combatting antimicrobial resistance - Explains how to apply multiple drug delivery mechanisms (MDR) to the target area in order to better combat antimicrobial resistance - Shows how nanomaterials are used as drug carriers in this context
Author: Hongye Yang
Publisher: Frontiers Media SA
ISBN: 2832555349
Category : Technology & Engineering
Languages : en
Pages : 258
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Book Description
Teeth and bones are typical hard tissues in vertebrates. Due to hierarchical structural characteristics and excellent mechanical properties, hard tissues play important roles in the human body, such as health protection, movement support, and food mastication. Once hard tissue defect occurs, our living quality will be seriously affected. In general, hard tissues lack the ability to self-repair, except for the regeneration ability of bone for small-scale defects. As a result, the past few decades have witnessed great progress in the field of biomaterials for hard tissue repair. Actually, both teeth and bone are masterpieces of biomineralization in nature, the repair and regeneration of hard tissues should be performed in a biomimetic way, either by using a biomimetic mineralization strategy or biomimetic materials.
