Advances in methods and tools for multi-omics data analysis

Advances in methods and tools for multi-omics data analysis PDF Author: Ornella Cominetti
Publisher: Frontiers Media SA
ISBN: 2832523420
Category : Science
Languages : en
Pages : 184

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Book Description

Advances in methods and tools for multi-omics data analysis

Advances in methods and tools for multi-omics data analysis PDF Author: Ornella Cominetti
Publisher: Frontiers Media SA
ISBN: 2832523420
Category : Science
Languages : en
Pages : 184

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Book Description


Advanced Methods and Tools for ECG Data Analysis

Advanced Methods and Tools for ECG Data Analysis PDF Author: Gari D. Clifford
Publisher: Artech House Publishers
ISBN:
Category : Computers
Languages : en
Pages : 412

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Book Description
This practical book is the first one-stop resource to offer a thorough, up-to-date treatment of the techniques and methods used in electrocardiogram (ECG) data analysis, from fundamental principles to the latest tools in the field. The book places emphasis on the selection, modeling, classification, and interpretation of data based on advanced signal processing and artificial intelligence techniques.

Machine Learning Advanced Dynamic Omics Data Analysis for Precision Medicine

Machine Learning Advanced Dynamic Omics Data Analysis for Precision Medicine PDF Author: Tao Zeng
Publisher: Frontiers Media SA
ISBN: 2889635546
Category :
Languages : en
Pages : 393

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Book Description


Random Walks and Electric Networks

Random Walks and Electric Networks PDF Author: Peter G. Doyle
Publisher: American Mathematical Soc.
ISBN: 1614440220
Category : Electric network topology
Languages : en
Pages : 174

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Book Description
Probability theory, like much of mathematics, is indebted to physics as a source of problems and intuition for solving these problems. Unfortunately, the level of abstraction of current mathematics often makes it difficult for anyone but an expert to appreciate this fact. Random Walks and electric networks looks at the interplay of physics and mathematics in terms of an example—the relation between elementary electric network theory and random walks —where the mathematics involved is at the college level.

Learning to Classify Text Using Support Vector Machines

Learning to Classify Text Using Support Vector Machines PDF Author: Thorsten Joachims
Publisher: Springer Science & Business Media
ISBN: 1461509076
Category : Computers
Languages : en
Pages : 218

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Book Description
Based on ideas from Support Vector Machines (SVMs), Learning To Classify Text Using Support Vector Machines presents a new approach to generating text classifiers from examples. The approach combines high performance and efficiency with theoretical understanding and improved robustness. In particular, it is highly effective without greedy heuristic components. The SVM approach is computationally efficient in training and classification, and it comes with a learning theory that can guide real-world applications. Learning To Classify Text Using Support Vector Machines gives a complete and detailed description of the SVM approach to learning text classifiers, including training algorithms, transductive text classification, efficient performance estimation, and a statistical learning model of text classification. In addition, it includes an overview of the field of text classification, making it self-contained even for newcomers to the field. This book gives a concise introduction to SVMs for pattern recognition, and it includes a detailed description of how to formulate text-classification tasks for machine learning.

Big Data in Omics and Imaging

Big Data in Omics and Imaging PDF Author: Momiao Xiong
Publisher: CRC Press
ISBN: 1498725805
Category : Mathematics
Languages : en
Pages : 701

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Book Description
Big Data in Omics and Imaging: Association Analysis addresses the recent development of association analysis and machine learning for both population and family genomic data in sequencing era. It is unique in that it presents both hypothesis testing and a data mining approach to holistically dissecting the genetic structure of complex traits and to designing efficient strategies for precision medicine. The general frameworks for association analysis and machine learning, developed in the text, can be applied to genomic, epigenomic and imaging data. FEATURES Bridges the gap between the traditional statistical methods and computational tools for small genetic and epigenetic data analysis and the modern advanced statistical methods for big data Provides tools for high dimensional data reduction Discusses searching algorithms for model and variable selection including randomization algorithms, Proximal methods and matrix subset selection Provides real-world examples and case studies Will have an accompanying website with R code The book is designed for graduate students and researchers in genomics, bioinformatics, and data science. It represents the paradigm shift of genetic studies of complex diseases– from shallow to deep genomic analysis, from low-dimensional to high dimensional, multivariate to functional data analysis with next-generation sequencing (NGS) data, and from homogeneous populations to heterogeneous population and pedigree data analysis. Topics covered are: advanced matrix theory, convex optimization algorithms, generalized low rank models, functional data analysis techniques, deep learning principle and machine learning methods for modern association, interaction, pathway and network analysis of rare and common variants, biomarker identification, disease risk and drug response prediction.

Data Analysis for Omic Sciences: Methods and Applications

Data Analysis for Omic Sciences: Methods and Applications PDF Author:
Publisher: Elsevier
ISBN: 0444640452
Category : Science
Languages : en
Pages : 732

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Book Description
Data Analysis for Omic Sciences: Methods and Applications, Volume 82, shows how these types of challenging datasets can be analyzed. Examples of applications in real environmental, clinical and food analysis cases help readers disseminate these approaches. Chapters of note include an Introduction to Data Analysis Relevance in the Omics Era, Omics Experimental Design and Data Acquisition, Microarrays Data, Analysis of High-Throughput RNA Sequencing Data, Analysis of High-Throughput DNA Bisulfite Sequencing Data, Data Quality Assessment in Untargeted LC-MS Metabolomic, Data Normalization and Scaling, Metabolomics Data Preprocessing, and more. - Presents the best reference book for omics data analysis - Provides a review of the latest trends in transcriptomics and metabolomics data analysis tools - Includes examples of applications in research fields, such as environmental, biomedical and food analysis

Multivariate Data Integration Using R

Multivariate Data Integration Using R PDF Author: Kim-Anh Lê Cao
Publisher: CRC Press
ISBN: 1000472191
Category : Mathematics
Languages : en
Pages : 331

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Book Description
Large biological data, which are often noisy and high-dimensional, have become increasingly prevalent in biology and medicine. There is a real need for good training in statistics, from data exploration through to analysis and interpretation. This book provides an overview of statistical and dimension reduction methods for high-throughput biological data, with a specific focus on data integration. It starts with some biological background, key concepts underlying the multivariate methods, and then covers an array of methods implemented using the mixOmics package in R. Features: Provides a broad and accessible overview of methods for multi-omics data integration Covers a wide range of multivariate methods, each designed to answer specific biological questions Includes comprehensive visualisation techniques to aid in data interpretation Includes many worked examples and case studies using real data Includes reproducible R code for each multivariate method, using the mixOmics package The book is suitable for researchers from a wide range of scientific disciplines wishing to apply these methods to obtain new and deeper insights into biological mechanisms and biomedical problems. The suite of tools introduced in this book will enable students and scientists to work at the interface between, and provide critical collaborative expertise to, biologists, bioinformaticians, statisticians and clinicians.

Advances in Bioinformatics

Advances in Bioinformatics PDF Author: Vijai Singh
Publisher: Springer Nature
ISBN: 9819984017
Category :
Languages : en
Pages : 365

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Book Description


Cytogenomics

Cytogenomics PDF Author: Thomas Liehr
Publisher: Academic Press
ISBN: 0128235802
Category : Science
Languages : en
Pages : 430

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Book Description
Cytogenomics demonstrates that chromosomes are crucial in understanding the human genome and that new high-throughput approaches are central to advancing cytogenetics in the 21st century. After an introduction to (molecular) cytogenetics, being the basic of all cytogenomic research, this book highlights the strengths and newfound advantages of cytogenomic research methods and technologies, enabling researchers to jump-start their own projects and more effectively gather and interpret chromosomal data. Methods discussed include banding and molecular cytogenetics, molecular combing, molecular karyotyping, next-generation sequencing, epigenetic study approaches, optical mapping/karyomapping, and CRISPR-cas9 applications for cytogenomics. The book's second half demonstrates recent applications of cytogenomic techniques, such as characterizing 3D chromosome structure across different tissue types and insights into multilayer organization of chromosomes, role of repetitive elements and noncoding RNAs in human genome, studies in topologically associated domains, interchromosomal interactions, and chromoanagenesis. This book is an important reference source for researchers, students, basic and translational scientists, and clinicians in the areas of human genetics, genomics, reproductive medicine, gynecology, obstetrics, internal medicine, oncology, bioinformatics, medical genetics, and prenatal testing, as well as genetic counselors, clinical laboratory geneticists, bioethicists, and fertility specialists. - Offers applied approaches empowering a new generation of cytogenomic research using a balanced combination of classical and advanced technologies - Provides a framework for interpreting chromosome structure and how this affects the functioning of the genome in health and disease - Features chapter contributions from international leaders in the field