Advances in Drug Therapy of Gastroesophageal Reflux Disease

Advances in Drug Therapy of Gastroesophageal Reflux Disease PDF Author: C. Scarpignato
Publisher: S. Karger AG (Switzerland)
ISBN: 9783805553605
Category : Medical
Languages : en
Pages : 371

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Book Description


Diagnosis and Treatment of Gastroesophageal Reflux Disease

Diagnosis and Treatment of Gastroesophageal Reflux Disease PDF Author: Michael F. Vaezi
Publisher: Springer
ISBN: 3319195247
Category : Medical
Languages : en
Pages : 165

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Book Description
This volume presents the most recent developments in diagnosis and treatment of patients with gastroesophageal reflux disease (GERD) and those who continue to be refractory to conventional GERD therapies. The book delineates the role of newly developed endoscopic therapies in GERD and outlines the best candidates for surgical fundoplication. Topics as the risks associated with GERD, lifestyle modification in GERD and the role of H2RA and proton pump inhibitor therapy in treating reflux disease are also explored. Written by authorities in the field, Diagnosis and Treatment of Gastroesophageal Reflux Disease is a concise yet comprehensive resource that is useful for primary care providers, gastroenterologists, pulmonologists, surgeons and ENT specialists.

Multidisciplinary Management of Gastroesophageal Reflux Disease

Multidisciplinary Management of Gastroesophageal Reflux Disease PDF Author: Sebastian F. Schoppmann
Publisher: Springer Nature
ISBN: 303053751X
Category : Medical
Languages : en
Pages : 217

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Book Description
This book presents a new, multi- and interdisciplinary approach to gastroesophageal reflux disease (GERD) and Barrett’s esophagus that reflects the latest advances in understanding of the disease. The role of each of the available diagnostic techniques, including endoscopy, histopathology, esophageal manometry, reflux monitoring, and EndoFLIP assessment, is carefully explained. The use of endoscopy for the purposes of mucosal ablation (radiofrequency ablation, cryoablation) and mucosal resection is described, and all aspects of anti-reflux surgery are covered, with detailed explanation of indications and techniques for standard fundoplication, endoscopic fundoplication, and surgical procedures using the LINX system and the EndoStim device. To assist the reader further, a novel interdisciplinary algorithm is presented for GERD diagnosis and treatment. In addition, the latest diagnostic and therapeutic approaches (including endoscopic and surgical resection and chemoradiation) are also presented for esophageal cancer and cancer palliation. A key feature of the book is its recognition of the contribution of different specialties in the management of GERD, and it will accordingly appeal to a wide range of practitioners.

Gastroesophageal Reflux Disease, An issue of Gastroenterology Clinics of North America

Gastroesophageal Reflux Disease, An issue of Gastroenterology Clinics of North America PDF Author: Joel E Richter
Publisher: Elsevier Health Sciences
ISBN: 0323290299
Category : Medical
Languages : en
Pages : 201

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Book Description
Gastroesophageal reflux disease and its complications effect 40 % of the US population. It is the most common reason for outpatient GI visits with treatment costs amounting to nearly $10 billion a year. Thisissue updates interested physicians on the new advance in GERD pathogenesis, diagnosis and medical/surgical treatment , especially over the last 5 years. Lots of advancements have been made in this time period and this will be a excellent reference book for the busy academic and community physician interested in GERD.

The Esophagus

The Esophagus PDF Author: Joel E. Richter
Publisher: John Wiley & Sons
ISBN: 1119599601
Category : Medical
Languages : en
Pages : 73

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Book Description
THE ESOPHAGUS The Esophagus investigates the anatomy, physiology, and pathology of the esophagus. This sixth edition, revised and updated throughout, also explores the diagnosis and treatment of various esophageal conditions. It includes treatment guidelines approved by the two largest gastroenterology societies, the ACG and AGA, as befits a work co-edited by two former presidents of those organizations. Advancements in diagnostics are presented, as are developments in the surgical and drug therapies. Presented in full colour, and boasting an unrivalled team of editors and contributing authors, The Esophagus Sixth Edition will find a home wherever the anatomy, physiology, and pathology of the esophagus are studied and taught. This book is accompanied by a website containing all the figures from the book in PowerPoint format. www.wiley.com/go/richter/esophagus6e Praise for the Fifth Edition: “There is absolutely no doubt that this edition of the textbook will maintain its status as the go-to reference for esophageal conditions, and will remain a highly utilized and clinically useful resource for novice and experienced physicians and surgeons alike.” (Gastroenterology, 1 July 2013)

Comparative Effectiveness of Management Strategies for Gastroesophageal Reflux Disease: Update

Comparative Effectiveness of Management Strategies for Gastroesophageal Reflux Disease: Update PDF Author: U. S. Department of Health and Human Services
Publisher: CreateSpace
ISBN: 9781484054802
Category : Medical
Languages : en
Pages : 244

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Book Description
Gastroesophageal reflux disease (GERD) is one of the most common health conditions affecting Americans. A study of an employed population in the U.S. estimated that more than 11,000 of 267,000 employees (4 %) suffered from GERD, contributing an average incremental cost to the employer of $3,355 per employee during a 3-year observation period—approximately 65 % related to prescription drugs. At the same time, it is well recognized that some drugs used to treat GERD (such as proton pump inhibitors) are overprescribed. A number of patients have frequent severe symptoms requiring long-term regular use of antireflux medications. For these individuals with chronic GERD, most authorities consider the goals of therapy to be an improvement in symptoms and quality of life, healing and maintenance of healed erosive esophagitis, and prevention of complications. However, there remains considerable uncertainty regarding how these objectives should be achieved. Among patients treated medically, several approaches are used, depending in part on the severity of symptoms and clinical response. These include intermittent, periodic, or continuous use of prescription or over-the-counter medications, especially histamine type 2 receptor antagonists (H2RAs) and proton pump inhibitors (PPIs). The availability of surgery and, more recently, endoscopic treatments has further complicated the choice among management strategies. The first Comparative Effectiveness Review (CER) published by the AHRQ focused on GERD. Key Questions addressed in that report concerned the comparative effectiveness of medical, surgical, and endoscopic treatments for improving objective and subjective outcomes in patients with this disease. The report also examined the relative efficacy of these interventions in specific patient subgroups as well as adverse event profiles. A number of developments since the publication of the 2005 review have necessitated an update. Among them are the publication of approx. 3,000 new studies; the introduction of novel drugs; the recognition of new drug safety considerations; and the withdrawal of previously approved endoscopic interventions and introduction of new endoscopic interventions. Also notable was the publication of a new consensus definition of GERD in 2006. The current report addresses developments in the treatment of GERD in adults and additionally includes sections on treatment of extraesophageal syndromes, including chronic cough, laryngitis, and asthma, which an expert panel considered to be of particular clinical importance. Key Questions in this review include: KQ1. What is the evidence of the comparative effectiveness of medical, surgical, and other newer forms of treatments for improving objective and subjective outcomes in patients with chronic GERD? Is there evidence that effectiveness varies by specific technique, procedure, or medication? Objective outcomes addressed include esophagitis healing, ambulatory pH, other indicators of reflux, need for medication, health care utilization, and incidence of esophageal stricture, Barrett's esophagus, or esophageal adenocarcinoma. Subjective outcomes include symptom frequency and severity, sleep/productivity, and overall quality of life. KQ2. Is there evidence that effectiveness of medical, surgical, and newer forms of treatments varies for specific patient subgroups? What are the characteristics of patients who have undergone these therapies, including the nature of previous medical therapy, severity of symptoms, age, sex, weight, and other demographic and medical factors? What are the provider characteristics for procedures, including provider volume and setting (e.g., academic vs. community)? KQ3. What are the short-term and long-term adverse events associated with specific medical, surgical, and other newer forms of therapies for GERD? Does the incidence of adverse events vary with duration of followup, specific surgical intervention, or patient characteristics?

Advances in Drug Therapy of Gastrointestinal Ulceration

Advances in Drug Therapy of Gastrointestinal Ulceration PDF Author: Andrew Garner
Publisher: John Wiley & Sons
ISBN:
Category : Medical
Languages : en
Pages : 332

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Book Description
This volume is based on the proceedings of the 38th annual Biological Council Symposium on Drug Action, held at the Royal Institution, London, in April 1988. The conference was addressed by 20 international experts on gastrointestinal ulcers.

Management of Gastroesophageal Reflux Disease

Management of Gastroesophageal Reflux Disease PDF Author: Santiago Horgan
Publisher: Springer Nature
ISBN: 3030480097
Category : Medical
Languages : en
Pages : 212

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Book Description
This book provides a comprehensive state-of-the-art overview on the established knowledge in the field of gastroesophageal reflux disease (GERD) as well as a current insight into new algorithms involving new diagnostic tools and new endoscopic and surgical techniques. The integration of these new findings in updated therapeutic decision making is demonstrated. The book reviews the latest literature on new diagnostic findings to better discriminate between different benign disorders of the esophagus and stomach. It describes the decision making to establish indications for the variety of established and new therapeutic options in the management of the disease. It also describes in detail new therapeutic techniques, which provides excellent back-up information for every clinician in daily practice. Management of Gastroesophageal Reflux Disease is a valuable resource for clinicians, surgeons, nurses, technicians, students and researchers with an interest in esophageal and upper GI- disease.

Laryngopharyngeal and Gastroesophageal Reflux

Laryngopharyngeal and Gastroesophageal Reflux PDF Author: Craig H. Zalvan
Publisher: Springer Nature
ISBN: 303048890X
Category : Medical
Languages : en
Pages : 487

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Book Description
This text comprehensively reviews the current state of the art in Laryngopharyngeal Reflux (LPR) together with a comprehensive explanation and description of the known gastroesophageal reflux (GERD) literature. With chapters written by experts from around the world, this text aims to deliver what is current in reflux recognition, diagnosis, reflux related complications, and the various treatment modalities. This is the first textbook to combine the most up to date knowledge of both LPR and GERD meant for both specialties and the general medicine population. Completely unique to the reflux literature is a section detailing the substantial benefits of a mostly plant based, Mediterranean style diet in the treatment of reflux disease. Encouraging patients to read and learn about diet and health is likely the most important step in improving their disease. The text provides direction to the caregiver on how to transition to a mostly plant-based diet. Review of myths, effects of diet in the setting of other disease states, and dietary consequences are explained. Guidelines on how to transition diet, dining out while maintaining a plant-based diet, and how to wean off medication, such as PPI, are also provided. Laryngopharyngeal and Gastroesophageal Reflux: A Comprehensive Guide to Diagnosis Treatment, and Diet-Based Approaches will provide the medical community with a resource to understand, teach, and provide the latest in LPR and GERD information to the caregiver and subsequently the patient.

Extraesophageal Manifestations of GERD

Extraesophageal Manifestations of GERD PDF Author: Anthony J. DiMarino, Jr.
Publisher: CRC Press
ISBN: 1040136362
Category : Medical
Languages : en
Pages : 192

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Book Description
In the past 30 years, gastroesophageal and reflux disease (GERD) has become an important area of clinical medicine. GERD has gradually become associated with other common but unexplained disorders. These conditions have been designated as the extraesophageal manifestations of GERD. Dr. Anthony J. DiMarino, Jr. and Dr. Sidney Cohen and their contributors have written Extraesophageal Manifestations of GERD with the purpose to identify associations with conditions like hoarseness, laryngeal cancer, sleep disorders, and dental caries, and to explore possible causation and mechanisms of disease or possible noncausal relationships. The extraesophageal disorders have become widely accepted in clinical practice. The evidence supporting the pathogenesis of these conditions falls into three major categories: guilt by association, observed mechanistic studies, and therapeutic response to treatment. Inside the pages of Extraesophageal Manifestations of GERD the reader will find recognition and balance in treating patients with common symptom-based disorders. Final resolution of some of the controversies inherent in these associations may require advanced diagnostic tools and advanced pharmacological therapies. With chapters written by experts in the fields of medicine, pediatrics, otolaryngology, and dentistry, Extraesophageal Manifestations of GERD will be a must have for gastroenterologists, internal medicine residents, surgeons, otolaryngologists, and pediatricians.