Author: Phil Beauchamp
Publisher:
ISBN: 9781537473482
Category :
Languages : en
Pages : 374
Get Book Here
Book Description
The goal of this book is to show beginning organic students how to interpret modern organic spectra to solve challenging organic structures, using IR, MS, 1H, 13C, DEPT and several 2D variations of NMR (COSY, HSQC/HETCOR and HMBC). Theory and instrumentation are not emphasized, but are sufficiently explained so that students have a basic idea about how each method works. Simulated spectra are used to remove real-life complexities that make structures too difficult for beginners to solve.It is exciting for beginning students to learn how to correctly generate an organic structure from a hodgepodge of lines and numbers. This book will show how to do that. A very specific plan of attack is presented to approach every problem in a step-by-step fashion, including a one page worksheet to summarize and organize the information to help focus their thinking for every "What if...'" question that might arise. Many simple problems are presented to show the mechanical steps of how each method is used to help solve organic structures. More complex problems are designed to be simple enough for beginning students, yet complex enough to require a sustained effort to solve using advanced NMR methods. Real molecules are not used, thereby avoiding the difficulties of overlapping peaks and/or extraneous peaks that should not be there and/or missing peaks that should be there. Students will find a clear path to a correct structure, without encountering real-life frustrations. Most of the common functional group features of organic chemistry are included. Oxygen (alcohols, ethers, esters), nitrogen (amines, amides, nitriles, nitro), halogens and/or sulfur atoms are included at key locations so that chemical shifts are different enough to distinguish each type of proton and carbon in the 1H, 13C, COSY, HETCOR/HSQC and HMBC spectra. This minimizes overlap so that the spectra are easier to interpret for beginning students. It is really the various types of NMR spectra that solve a structure. For the more complex problems, 1H, 13C, DEPT, COSY, HETCOR/HSQC and HMBC are included. An IR chapter is included and a simulated IR is provided in structure problems to provide helpful functional group clues, and details about how alkenes and/or aromatic rings are substituted. In the mass spectrometry chapter, examples of the most common organic monofunctional groups are presented and discussed. However, in complex structure problems, MS is mainly used to provide a molecular weight and indicate the presence of nitrogen, chlorine, bromine and/or sulfur when they are present. These clues can be used to obtain a molecular formula and degrees of unsaturation. Pi bonds can be distinguished from rings using the 13C, which provides a good starting point for solving a structure. Problems range from: shorter structure problems that show how each technique can provide clues to solve a structure; to intermediate level problems that require multiple techniques; to very challenging structure problems that require all of the techniques presented in this book. This workbook will work best for students who are learning basic organic structure determination, and want or need to build on what they are learning to take it to the next level. This can be accomplished in a classroom setting or through self-study by motivated students. If you are an instructor who loves spectroscopy, you might consider trying this approach in one of your course settings to judge for yourself if it works for you and your students. If you are an interested student who can't get enough spectroscopy, just have fun working problems.
Author: L. D. Field
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 304
Get Book Here
Book Description
Offers a realistic approach to solving problems used by organic chemists. Covering all the major spectroscopic techniques, it provides a graded set of problems that develop and consolidate students' understanding of organic spectroscopy. This edition contains more elementary problems and a modern approach to NMR spectra.
Author: S. A. Richards
Publisher: John Wiley & Sons
ISBN: 0470977221
Category : Science
Languages : en
Pages : 345
Get Book Here
Book Description
This book describes the use of NMR spectroscopy for dealing with problems of small organic molecule structural elucidation. It features a significant amount of vital chemical shift and coupling information but more importantly, it presents sound principles for the selection of the techniques relevant to the solving of particular types of problem, whilst stressing the importance of extracting the maximum available information from the simple 1-D proton experiment and of using this to plan subsequent experiments. Proton NMR is covered in detail, with a description of the fundamentals of the technique, the instrumentation and the data that it provides before going on to discuss optimal solvent selection and sample preparation. This is followed by a detailed study of each of the important classes of protons, breaking the spectrum up into regions (exchangeables, aromatics, heterocyclics, alkenes etc.). This is followed by consideration of the phenomena that we know can leave chemists struggling; chiral centres, restricted rotation, anisotropy, accidental equivalence, non-first-order spectra etc. Having explained the potential pitfalls that await the unwary, the book then goes on to devote chapters to the chemical techniques and the most useful instrumental ones that can be employed to combat them. A discussion is then presented on carbon-13 NMR, detailing its pros and cons and showing how it can be used in conjunction with proton NMR via the pivotal 2-D techniques (HSQC and HMBC) to yield vital structural information. Some of the more specialist techniques available are then discussed, i.e. flow NMR, solvent suppression, Magic Angle Spinning, etc. Other important nuclei are then discussed and useful data supplied. This is followed by a discussion of the neglected use of NMR as a tool for quantification and new techniques for this explained. The book then considers the safety aspects of NMR spectroscopy, reviewing NMR software for spectral prediction and data handling and concludes with a set of worked Q&As.
Author: Phillip Crews
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 664
Get Book Here
Book Description
"Organic Structure Analysis, Second Edition, is the only text that teaches students how to solve structures as they are solved in actual practice. Ideal for advanced undergraduate and graduate courses in organic structure analysis, organic structure identification, and organic spectroscopy, it emphasizes real applications-integrating theory as needed - and introduces students to the latest spectroscopic methods." --Book Jacket.
Author: Maria-Magdalena Cid
Publisher: John Wiley & Sons
ISBN: 3527664637
Category : Science
Languages : en
Pages : 554
Get Book Here
Book Description
Intended for advanced readers, this is a review of all relevant techniques for structure analysis in one handy volume. As such, it provides the latest knowledge on spectroscopic and related techniques for chemical structure analysis, such as NMR, optical spectroscopy, mass spectrometry and X-ray crystallography, including the scope and limitation of each method. As a result, readers not only become acquainted with the techniques, but also the advantages of the synergy between them. This enables them to choose the correct analytical method for each problem, saving both time and resources. Special emphasis is placed on NMR and its application to absolute configuration determination and the analysis of molecular interactions. Adopting a practical point of view, the author team from academia and industry guarantees both solid methodology and applications essential for structure determination, equipping experts as well as newcomers with the tools to solve any structural problem.
Author: Donald L. Pavia
Publisher:
ISBN: 9789865632021
Category : Organic compounds
Languages : en
Pages : 764
Get Book Here
Book Description
Author: Muhammad Akhyar Farrukh
Publisher: BoD – Books on Demand
ISBN: 9535107151
Category : Technology & Engineering
Languages : en
Pages : 551
Get Book Here
Book Description
Spectroscopy is the study of absorption and emission of electromagnetic radiation due to the interaction between matter and energy that energy depends on the specific wavelength of electromagnetic radiation. This field has proven invaluable research tool in a number of areas including chemistry, physics, biology, medicine and ecology. The spectroscopic field of research is growing day-by-day and scientists are exploring new areas in this field by introducing new techniques. The main purpose of this book is to highlight these new spectroscopic techniques like Magnetic Induction Spectroscopy, Laser-Induced Breakdown Spectroscopy, X-ray Photoelectron Spectroscopy, Low Energy Electron Loss Spectroscopy, Micro- to Macro-Raman Spectroscopy, Liquid-Immersion Raman Spectroscopy, High-Resolution Magic Angle Spinning (HR-MAS) Nuclear Magnetic Resonance (NMR) Spectroscopy, Injection and Optical Spectroscopy, and Nano Spectroscopy. This book is divided into five sections including General Spectroscopy, Advanced Spectroscopy, Nano Spectroscopy, Organic Spectroscopy, and Physical Spectroscopy which cover topics from basic to advanced levels which will provide a good source of learning for teaching and research purposes.
Author: Jeffrey H. Simpson
Publisher: Academic Press
ISBN: 0123849705
Category : Science
Languages : en
Pages : 591
Get Book Here
Book Description
"The second edition of this book comes with a number of new figures, passages, and problems. Increasing the number of figures from 290 to 448 has necessarily added considerable length, weight, and, expense. It is my hope that the book has not lost any of its readability and accessibility. I firmly believe that most of the concepts needed to learn organic structure determination using nuclear magnetic resonance spectroscopy do not require an extensive mathematical background. It is my hope that the manner in which the material contained in this book is presented both reflects and validates this belief"--
Author: Y R Sharma
Publisher: S. Chand Publishing
ISBN: 8121928842
Category : Science
Languages : en
Pages : 356
Get Book Here
Book Description
PRINCIPLES AND CHEMICAL APPLICATIONS FOR B.SC.(HONS) POST GRADUATE STUDENTS OF ALL INDIAN UNIVERSITIES AND COMPETITIVE EXAMINATIONS.
Author: Laurence M. Harwood
Publisher:
ISBN: 9780198557555
Category : Medical
Languages : en
Pages : 91
Get Book Here
Book Description
An understanding of spectroscopic techniques in the analysis of chemical structures is essential to all chemistry degree courses. This new addition to the Oxford Chemistry Primers series provides the essential material needed by undergraduates, in a compact form. It will be beneficial to postgraduates in organic chemistry as reference material in their daily research.
