Accelerated Aging

Accelerated Aging PDF Author: Robert L. Feller
Publisher: Getty Publications
ISBN: 0892361255
Category : Art
Languages : en
Pages : 292

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Book Description
Accelerated Aging: Photochemical and Thermal Aspects represents the culmination of more than 40 years of research by noted scientist Robert L. Feller. The book focuses on the long-term performance of materials such as wool, dyes, and organic compounds; their resistance to change when exposed to environmental factors such as oxygen, ozone, moisture, heat, and light; and their physical durability with handling and use over time. Processes of deterioration are discussed based on speeded-up laboratory studies designed to clarify the chemical reactions involved and their physical consequences.

Research Agenda for Test Methods and Models to Simulate the Accelerated Aging of Infrastructure Materials

Research Agenda for Test Methods and Models to Simulate the Accelerated Aging of Infrastructure Materials PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309184126
Category : Technology & Engineering
Languages : en
Pages : 43

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Book Description
In the next several decades, a significant percentage of the country's transportation, communications, environmental, and power system infrastructures, as well as public buildings and facilities, will have to be renewed or replaced. Next-generation infrastructure will have to meet very high expectations in terms of durability, constructability, performance, and life-cycle cost. One way of meeting future expectations will be through improved, high-performance materials, but before new materials can be confidently deployed in the field, a thorough and comprehensive understanding must be developed of their long-term performance in a variety of applications and physical environments. The National Science Foundation (NSF) has launched an initiative to promote the development of innovative short-term laboratory or in-situ tests for making accurate, reliable predictions of the long-term performance of materials and requested that the National Research Council (NRC) conduct a workshop as a reconnaissance-level assessment of models and methods that are being used, or potentially could be used, to determine the long-term performance of infrastructure materials and components.

Practical Geriatric Oncology

Practical Geriatric Oncology PDF Author: Arti Hurria
Publisher: Cambridge University Press
ISBN: 1139490591
Category : Medical
Languages : en
Pages :

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Book Description
The risk of cancer increases with age, and the number of older adults seeking treatment is increasing dramatically in line with the aging population. The care of older patients differs from that of younger adults because of differences in the biology of the tumor, age-related differences in host physiology, comorbidity burden and psychosocial issues, which might impact the efficacy and side effects of cancer therapy. Practical Geriatric Oncology is a comprehensive, evidence-based text that synthesizes the growing literature in this field and provides practical guidelines to the care of older adults with cancer. Coverage includes patient assessment, management of solid tumors and hematologic malignancies, the impact of age on the pharmacology of cancer therapy, surgical oncology and radiation oncology in the older adult, symptom management and supportive care. In addition to serving as core reading for oncologists and hematologists, the book will also be a useful work for other healthcare professionals who provide oncology care, including surgeons, radiation oncologists, palliative care doctors, primary care providers, geriatricians and nurses.

Fast Track to Aging Backwards

Fast Track to Aging Backwards PDF Author: Miranda Esmonde-White
Publisher: Random House Canada
ISBN: 0735275211
Category : Health & Fitness
Languages : en
Pages : 0

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Book Description
Drawing on her groundbreaking anti-aging movement principles, bestselling fitness expert Miranda Esmonde-White walks you through 6 ways to rejuvenate your body and mind, paired with 30 days of stretching-and-strengthening workouts that effectively reverse the aging process. Miranda Esmonde-White has already given us the Bible on movement as a way to reverse aging with her New York Times and Globe and Mail bestseller Aging Backwards. But getting started on something that will change your life is always the hardest part! The Fast Track to Aging Backwards is Miranda's master class on how to begin her healing, revitalizing and scientifically endorsed programme of stretching and strengthening--and how to make it stick. First she outlines, step by step, 6 ways to change your attitude to aging and reverse its effects, from describing helpful small changes to your daily routine that will help you form new habits; to how to find the balance between moving like the Tin Man and flopping like the Scarecrow; to showing that for maximum painfree living, our bodies need a gentle approach to exercising that is all about respecting the way our bodies are designed to move. As Miranda says, "Relaxation is the new strengthening." Exclusively for this book, she has also created 4 workouts designed to carry you every step of the way through the first month of her programme, targeting every part of your body. Laid out with clear instructions, black-and-white photos and insider's tips on how to make every movement count, these workouts will give you the edge you need to quickly achieve your best results. The Fast Track to Aging Backwards is a countdown to a healthier and more youthful you.

Early Vascular Aging (EVA)

Early Vascular Aging (EVA) PDF Author: Pedro Guimarães Cunha
Publisher: Elsevier
ISBN: 0443155135
Category : Medical
Languages : en
Pages : 772

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Book Description
Early Vascular Aging (EVA): New Directions in Cardiovascular Protection, Second Edition continues to be the most comprehensive and authoritative resource on premature alterations in artery structure and function. The book presents a novel approach to the problem of cardiovascular disease, showing it in relation to great vessels disease and revealing a comprehensive approach to the problem of increased rigidity of the great vessels, its causes, and further consequences. This second edition contains completely updated content with expanded coverage of basic and translational research, systematic reviews of the most prominent literature, discussion of applicability of new evidence and more. Written by an international team of clinicians and researchers, this is a valuable resource to basic and translational scientists, clinical researchers and clinicians in the cardiovascular field interested in prevention, diagnosis and treatment of EVA. Contains all the relevant information available on the main paradigm shifts in vascular aging research, from different fields of knowledge (from basic biology to epidemiology) Reviews the most prominent evidence produced on early vascular aging (EVA), highlighting recent research advances, clinical applications, and research opportunities Formulates, in each chapter, a set of research questions that need to be addressed, challenging the vast research community to take on new directions and collaborations

Epigenetics of Aging

Epigenetics of Aging PDF Author: Trygve O. Tollefsbol
Publisher: Springer Science & Business Media
ISBN: 1441906398
Category : Medical
Languages : en
Pages : 462

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Book Description
Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

Endocrine and Metabolic Late Effects in Cancer Survivors

Endocrine and Metabolic Late Effects in Cancer Survivors PDF Author: Francesco Felicetti (Oncologist)
Publisher:
ISBN: 9783318067903
Category :
Languages : en
Pages : 162

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Book Description
This book analyzes in detail all aspects related to endocrine and metabolic late effects observed in patients treated for cancer, both in childhood and adulthood. The chapters focusing on the possible pathogenic mechanisms of late effects (i.e., premature aging and chronic inflammation) and on bone health in cancer survivors are particularly interesting and innovative. The volume also deals with hypothalamic-pituitary, thyroid and gonadal disorders, including infertility and how to prevent it. Finally, the relationship between metabolic alterations and cardiovascular diseases in cancer survivors is addressed. Thanks to advances in cancer treatment and supportive care, the five-year survival rate of cancer patients is constantly increasing. However, this undisputable success of medicine has a flip side: the late adverse effects of anticancer therapies. Pediatric oncologists were the first to cope with late complications of treatments, but today also adult oncologists and onco-hematologists recognize the relevance of this issue. Even though late effects observed in cancer survivors can affect any organ or system, endocrine and metabolic dysfunctions are the most frequently reported. Endocrine complications rarely influence life expectancy of cancer survivors, but they can significantly impact morbidity and quality of life. Among endocrine adverse effects, severe hypothalamic damage may be considered the most harmful in survivors, leading to morbid obesity, propensity to metabolic syndrome and cardiovascular disease. This book aims to disseminate the knowledge about endocrine and metabolic adverse effects of cancer therapies and about survivorship care. Since the number of cancer survivors is steadily growing in the general population, this publication is intended not only for endocrinologists but also for oncologists, onco-hematologists, internists, pediatric specialists in those areas and general practitioners, with the aim to better counsel and monitor cancer survivors.

Cellulose

Cellulose PDF Author: Arnaud Lejeune
Publisher: Nova Biomedical Books
ISBN: 9781608763887
Category : Cellulose
Languages : en
Pages : 0

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Book Description
Cellulose is the most widely spread organic polymer found in nature, since it constitutes the main component of the membrane of plant cell. It is well-known that cellulose is a very important and fascinating biopolymer and an almost inexhaustible and renewable raw material. This book provides a synthesis of the old knowledge and the development of different studies which contribute to the understanding of the structure of cellulose allomorphs. In addition, cellulosic ethanol has been taken as a promising alternative energy source for the non-renewable fossil fuel. This book reviews the development of biochemical conversion of biomass materials into cellulosic ethanol, including previous achievements, current status, and future work. The various aspects of natural and accelerated ageing of cellulose are also presented and discussed. Other chapters in this book explore the basic principles of cellulose oxidation chemistry with a focus on different products of the reactions. The main part of the chapter focuses on both known and newly proposed applications of oxidised celluloses in medical, cosmetic, hygiene and food industry. A critical analysis is also made of the literature concerned with the kinetics of cellulose degradation. Furthermore, this book reviews bacterial cellulose (BC), an outstanding biomaterial with unique properties, including high water holding capacity, high crystallinity and ultrafine fibre network. These properties support a wide range of applications, in human and veterinary medicine, odonthology, pharmaceutical industry, acoustic and filter membranes, biotechnological devices and in the food and paper industry.

Artificial Aging as a Predictor of Paper's Future Useful Life

Artificial Aging as a Predictor of Paper's Future Useful Life PDF Author: Helmut Bansa
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 32

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Book Description
An experiment with the artificial aging of paper which--in contrast with the usual practice--was carried out at relatively low temperatures (i.e., 50-95 degrees Celsius), and not on laboratory handsheets, but on naturally aged paper from the commercial production of four centuries, produced results justifying the thesis that there may be at best an accidental agreement between the results of artificial aging at high temperatures and natural aging. The chemical processes that take place as paper ages appear to take different temperature-specific courses, so that it is not possible to draw any conclusions from short-term expiration at one (elevated) temperature about the long-term expiration at another (room) temperature. If artificial aging cannot be dispensed with despite this uncertainty, aging should take place at 80 degrees Celsius and 65% relative humidity. The data collected are displayed in 24 tables and 10 figures. (Author/SD)

Never Feel Old Again

Never Feel Old Again PDF Author: Raymond Francis
Publisher: Simon and Schuster
ISBN: 0757317332
Category : Health & Fitness
Languages : en
Pages : 336

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Book Description
Ray Francis' first book, Never Be Sick Again, helped thousands of people put their "incurable" diseases into remission and enabled thousands more to shed excess weight, improve their cholesterol profiles, and achieve peak immunity from disease. Now Francis brings his revolutionary approach to anyone who wants to enjoy robust health and wellness and reverse accelerated aging. As Francis explains, just like an automobile, the body ages as a result of accumulated repair deficits, or a lack of maintenance. Fortunately, the human body is a self-repairing system, and in this latest book, Francis shows readers how to stay in good repair and keep the aging process at bay. His revolutionary approach counters the one-size-fits-all approach of most conventional anti-aging treatments on the market by targeting specific imbalances that manifest through "aging" symptoms. Botox injections, plastic surgery, and even hormone-replacement therapies don't yield meaningful results because they fail to activate the body's self-repair mechanisms; what's more, sometimes these treatments compound the problem by introducing additional toxins into the body. Never Feel Old Again provides a fundamental understanding of why we experience accelerated aging and teaches readers to look and feel their best and be healthy at any age.