Abstracts of Papers Presented at the 1991 Meeting on the Role of Isoform Diversity in Cytoskeletal Functions, April 24-28, 1991

Abstracts of Papers Presented at the 1991 Meeting on the Role of Isoform Diversity in Cytoskeletal Functions, April 24-28, 1991 PDF Author:
Publisher:
ISBN:
Category : Cytoskeleton
Languages : en
Pages : 116

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Abstracts of Papers Presented at the 1991 Meeting on the Role of Isoform Diversity in Cytoskeletal Functions

Abstracts of Papers Presented at the 1991 Meeting on the Role of Isoform Diversity in Cytoskeletal Functions PDF Author:
Publisher:
ISBN:
Category : Cytoskeletal proteins
Languages : en
Pages : 92

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Current Catalog

Current Catalog PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1628

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Book Description
First multi-year cumulation covers six years: 1965-70.

National Library of Medicine Current Catalog

National Library of Medicine Current Catalog PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1332

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Index of Conference Proceedings

Index of Conference Proceedings PDF Author: British Library. Document Supply Centre
Publisher:
ISBN:
Category : Conference proceedings
Languages : en
Pages : 516

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Tubulin

Tubulin PDF Author: Wei Yamauchi
Publisher: Nova Science Publishers
ISBN: 9781621001416
Category : Tubulins
Languages : en
Pages : 0

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Book Description
Tubulin is one of several members of a small family of globular proteins. The most common members of the tubulin family are α-tubulin and β-tubulin, the proteins that make up microtubules. In this book the authors present topical research in the study of the structure, functions and roles in disease of tubulin. Topics discussed in this compilation include microtubule plus-end tracking proteins in neuronal development and nervous system disorders; trypanosome tubulin molecules as targets for drug and vaccine development for protozoan infections; tubulin inhibitors as vascular disrupting agents and evolution and co-evolution of tubulin's carboxy-terminal tails and mitochondria.

Insulin and IGFs

Insulin and IGFs PDF Author:
Publisher: Academic Press
ISBN: 0080922155
Category : Science
Languages : en
Pages : 766

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Book Description
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.This volume focuses on insulin and IGFs. - Longest running series published by Academic Press - Contributions by leading international authorities

C. elegans

C. elegans PDF Author: Ian A. Hope
Publisher: OUP Oxford
ISBN: 019159198X
Category : Science
Languages : en
Pages : 306

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Book Description
Caenorhabditis Elegans has been a popular model organism for biological research for over thirty years and has been used to investigate many aspects of animal development, for example apoptosis, the Hox genes, signal transduction pathways, and the development of the nervous system. It has recently taken on new importance with the publication of the entire genome sequence in 1998. The first chapter gives all the basic information on C. elegans required to use it: it's natural history, anatomy, life cycle, development, and evolution. Information on how to obtain, grow, and maintain C. elegans for use as a model system is given in Chapter 4. Chapters 2 and 3 describe the genome project and show how to use genome sequence information by searching the database for homologues using different search methods and then how to analyse the search data. The next chapter gives the essential practical details of transformation and common uses for the technique. Chapter 6 covers reverse genetics and describes strategies for gene inactivation that are known to work in C elegans: epigenetic inactivation and mutational germ line inactivation. Chapter 7 is designed to help the user analyse phenotype by microscopy and includes Normaski, fluorescence, 4-dimensional, and electron microscopy. Techniques for studying the neurobiology of C. elegans are given in chapter 8. Chapter 9 describes the three commonly used approaches for studying gene expression and Chapter 10 deals with the common methods of molecular biology essential for gene characterization. C. elegans is not the ideal organism for biochemical studies, but chapter 11 describes several procedures for producing biochemically useful quantities of pure tissues. The final chapter is about conventional genetics and details the standard procedures for selfing and crossing; mutagenesis and mutant screening; characterization of mutants; gene mapping; temperature-shift experiments and mosaic analysis. Caenorhabditis Elegans: A Practical Approach will therefore provide all the background information necessary for use of C. elegans as a model system.

The Human Endometrium

The Human Endometrium PDF Author: Carlo Bulletti
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 522

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Book Description
The structural, biochemical and clinical events related to menstruation, implantation, parturition, endometriosis, abnormal uterine bleeding and endometrial cancer are discussed in this comprehensive volume on the biological functions of the endometrium. New topics, such as the biochemical and molecular mechanisms regulating maternal embryonic interaction, are explored, and gynecologic endoscopy and therapeutic tools are discussed. The proceedings of the first conference is also available from the Academy, as volume 622 of The Annals of The New York Academy of Science.

Extrasynaptic GABAA Receptors

Extrasynaptic GABAA Receptors PDF Author: Adam C. Errington
Publisher: Springer
ISBN: 149391426X
Category : Medical
Languages : en
Pages : 301

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Book Description
GABA is the principal inhibitory neurotransmitter in the CNS and acts via GABAA and GABAB receptors. Recently, a novel form of GABAA receptor-mediated inhibition, termed “tonic” inhibition, has been described. Whereas synaptic GABAA receptors underlie classical “phasic” GABAA receptor-mediated inhibition (inhibitory postsynaptic currents), tonic GABAA receptor-mediated inhibition results from the activation of extrasynaptic receptors by low concentrations of ambient GABA. Extrasynaptic GABAA receptors are composed of receptor subunits that convey biophysical properties ideally suited to the generation of persistent inhibition and are pharmacologically and functionally distinct from their synaptic counterparts. This book highlights ongoing work examining the properties of recombinant and native extrasynaptic GABAA receptors and their preferential targeting by endogenous and clinically relevant agents. In addition, it emphasizes the important role of extrasynaptic GABAA receptors in GABAergic inhibition throughout the CNS and identifies them as a major player in both physiological and pathophysiological processes.