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Author: Nick Lane
Publisher:
ISBN: 9781781250372
Category : Cells
Languages : en
Pages : 0
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Book Description
A game-changing book on the origins of life, called the most important scientific discovery 'since the Copernican revolution' in The Observer.
Author: Nick Lane
Publisher:
ISBN: 9781781250372
Category : Cells
Languages : en
Pages : 0
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Book Description
A game-changing book on the origins of life, called the most important scientific discovery 'since the Copernican revolution' in The Observer.
Author: Nick Lane
Publisher: OUP Oxford
ISBN: 9780191513015
Category : Science
Languages : en
Pages : 370
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Book Description
Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that. Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death. 'An extraordinary account of groundbreaking modern science... The book abounds with interesting and important ideas.' Mark Ridley, Department of Zoology, University of Oxford
Author: Philip Stott
Publisher: Reformation Media & Press
ISBN: 9780972135429
Category : Religion
Languages : en
Pages : 172
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Book Description
"Vital Questions" examines issues which have enormous influence in shaping the attitudes of our society and the way we think and look at life. Most of us have assumed for years that there must be overwhelming proof for such well established ideas as the Big bang, Relativity, and Evolution. On closer investigation one finds that the evidence is astonishingly flimsy. A number of theories taken as indisputable, from primary school to university, are examined and found to be in serious doubt.
Author: David Emerald
Publisher:
ISBN: 9780996871839
Category : Business & Economics
Languages : en
Pages : 226
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Book Description
Finalist, 2019 Indie Book Awards, Careers Category Transform Workplace Drama into Workforce Empowerment! If you have ever experienced infighting, such as a team or a department pitting itself against another team or department; if you have ever worked for a micromanaging and overbearing boss; if you have ever navigated the changes that come with a merger or other significant restructuring process, then you have had a front-row seat for organizational drama. 3 Vital Questions is a teaching story about transforming workplace drama and its heavy costs to organizations. Working late at night, Lucas, a middle manager in a large organization, meets a custodian named Ted. The two strike up a friendship as Ted teaches Lucas three vital questions with the power to transform the disillusionment he is experiencing at work. Readers follow Lucas as he learns how to shift from feeling like a Victim to acting as a Creator in his career. With the wise guidance of Ted and Kasey, a senior manager, Lucas applies the three vital questions and begins transforming his workplace relationships, with exciting results. At home, Lucas and his wife Sarah discover how the questions can spark creative collaboration with each other and their two young children. This long-awaited and highly enjoyable read by the author of the bestselling self-leadership title, The Power of TED* (*The Empowerment Dynamic) ushers in a new era of possibility for the world of work. This book teaches David Emerald's groundbreaking 3 Vital Questions(R) approach for empowering leaders and teams to become collaborative, engaged, and resilient in the face of the rapid changes that mark today's increasingly complex competitive environment.
Author: Nick Lane
Publisher: Profile Books
ISBN: 1847652220
Category : Science
Languages : en
Pages : 353
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Book Description
Winner of the 2010 Royal Society Prize for science books Powerful new research methods are providing fresh and vivid insights into the makeup of life. Comparing gene sequences, examining the atomic structure of proteins and looking into the geochemistry of rocks have all helped to explain creation and evolution in more detail than ever before. Nick Lane uses the full extent of this new knowledge to describe the ten greatest inventions of life, based on their historical impact, role in living organisms today and relevance to current controversies. DNA, sex, sight and consciousnesses are just four examples. Lane also explains how these findings have come about, and the extent to which they can be relied upon. The result is a gripping and lucid account of the ingenuity of nature, and a book which is essential reading for anyone who has ever questioned the science behind the glories of everyday life.
Author: Nick Lane
Publisher: W. W. Norton & Company
ISBN: 0393651495
Category : Science
Languages : en
Pages : 275
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Book Description
From the renowned biochemist and author of The Vital Question, an illuminating inquiry into the Krebs cycle and the origins of life. “Nick Lane’s exploration of the building blocks that underlie life’s big fundamental questions—the origin of life itself, aging, and disease—have shaped my thinking since I first came across his work. He is one of my favorite science writers.”—Bill Gates What brings the Earth to life, and our own lives to an end? For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight —how the same simple chemistry gives rise to life and causes our demise. Lane is among the vanguard of researchers asking why the Krebs cycle, the “perfect circle” at the heart of metabolism, remains so elusive more than eighty years after its discovery. Transformer is Lane’s voyage, as a biochemist, to find the inner meaning of the Krebs cycle—and its reverse—why it is still spinning at the heart of life and death today. Lane reveals the beautiful, violent world within our cells, where hydrogen atoms are stripped from the carbon skeletons of food and fed to the ravenous beast of oxygen. Yet this same cycle, spinning in reverse, also created the chemical building blocks that enabled the emergence of life on our planet. Now it does both. How can the same pathway create and destroy? What might our study of the Krebs cycle teach us about the mysteries of aging and the hardest problem of all, consciousness? Transformer unites the story of our planet with the story of our cells—what makes us the way we are, and how it connects us to the origin of life. Enlivened by Lane’s talent for distilling and humanizing complex research, Transformer offers an essential read for anyone fascinated by biology’s great mysteries. Life is at root a chemical phenomenon: this is its deep logic.
Author: Nikolay Gavrilovich Chernyshevsky
Publisher:
ISBN:
Category :
Languages : en
Pages : 348
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Book Description
Author: Valeria Luiselli
Publisher: Coffee House Press
ISBN: 1566894964
Category : Literary Collections
Languages : en
Pages : 72
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Book Description
"Part treatise, part memoir, part call to action, Tell Me How It Ends inspires not through a stiff stance of authority, but with the curiosity and humility Luiselli has long since established." —Annalia Luna, Brazos Bookstore "Valeria Luiselli's extended essay on her volunteer work translating for child immigrants confronts with compassion and honesty the problem of the North American refugee crisis. It's a rare thing: a book everyone should read." —Stephen Sparks, Point Reyes Books "Tell Me How It Ends evokes empathy as it educates. It is a vital contribution to the body of post-Trump work being published in early 2017." —Katharine Solheim, Unabridged Books "While this essay is brilliant for exactly what it depicts, it helps open larger questions, which we're ever more on the precipice of now, of where all of this will go, how all of this might end. Is this a story, or is this beyond a story? Valeria Luiselli is one of those brave and eloquent enough to help us see." —Rick Simonson, Elliott Bay Book Company "Appealing to the language of the United States' fraught immigration policy, Luiselli exposes the cracks in this foundation. Herself an immigrant, she highlights the human cost of its brokenness, as well as the hope that it (rather than walls) might be rebuilt." —Brad Johnson, Diesel Bookstore "The bureaucratic labyrinth of immigration, the dangers of searching for a better life, all of this and more is contained in this brief and profound work. Tell Me How It Ends is not just relevant, it's essential." —Mark Haber, Brazos Bookstore "Humane yet often horrifying, Tell Me How It Ends offers a compelling, intimate look at a continuing crisis—and its ongoing cost in an age of increasing urgency." —Jeremy Garber, Powell's Books
Author: Ann Florini
Publisher: Columbia University Press
ISBN: 0231141580
Category : Business & Economics
Languages : en
Pages : 378
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Book Description
The Right to Know is a timely and compelling consideration of a vital question: What information should governments and other powerful organizations disclose? Excessive secrecy corrodes democracy, facilitates corruption, and undermines good public policymaking, but keeping a lid on military strategies, personal data, and trade secrets is crucial to the protection of the public interest. Over the past several years, transparency has swept the world. India and South Africa have adopted groundbreaking national freedom of information laws. China is on the verge of promulgating new openness regulations that build on the successful experiments of such major municipalities as Shanghai. From Asia to Africa to Europe to Latin America, countries are struggling to overcome entrenched secrecy and establish effective disclosure policies. More than seventy now have or are developing major disclosure policies or laws. But most of the world's nearly 200 nations do not have coherent disclosure laws; implementation of existing rules often proves difficult; and there is no consensus about what disclosure standards should apply to the increasingly powerful private sector. As governments and corporations battle with citizens and one another over the growing demand to submit their secrets to public scrutiny, they need new insights into whether, how, and when greater openness can serve the public interest, and how to bring about beneficial forms of greater disclosure. The Right to Know distills the lessons of many nations' often bitter experience and provides careful analysis of transparency's impact on governance, business regulation, environmental protection, and national security. Its powerful lessons make it a critical companion for policymakers, executives, and activists, as well as students and scholars seeking a better understanding of how to make information policy serve the public interest.
Author: Nick Lane
Publisher: Oxford University Press, USA
ISBN: 0198607830
Category : Health & Fitness
Languages : en
Pages : 385
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Book Description
Oxygen offers fresh perspectives on our own lives and deaths, explaining modern killer diseases, why we age, and what we can do about it. Advancing revelatory new ideas, following chains of evidence, the book ranges through many disciplines, from environmental sciences to molecular medicine. Damage to DNA caused by oxidative stress appears to explain aging and many of its diseases, hence the popularity in alternative health circles of antioxidants. But antioxidants alone fail to prevent aging. Lane suggests two different avenues of study: modulation of the immune system, which generates free radicals as part of its defense against infectious diseases; and ways of improving the health of our cellular mitochondria, on which many age-related ailments seem to depend. Provocative and complexly argued. Copyright ©Kirkus Reviews, used with permission.
