Thermodynamics of Membrane Receptors and Channels

Thermodynamics of Membrane Receptors and Channels PDF Author: Meyer B. Jackson
Publisher: CRC Press
ISBN: 9780849369087
Category : Science
Languages : en
Pages : 454

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Book Description
Thermodynamics of Membrane Receptors and Channels synthesizes a wealth of new information regarding the biophysics of membrane proteins. New insights provided by molecular genetics, single channel recording, and high resolution structural techniques are discussed from a conceptual perspective. Basic theoretical topics are introduced, developed, and then extensively illustrated with recent results from the literature or data from the authors' own laboratories. Theoretical and experimental information is incorporated into in-depth discussions of ion permeation mechanisms, ion channel and receptor conformational changes, aggregate activity of complexes of lipids and proteins, and how coupling is achieved between different energy modes in the many transduction systems residing in biomembranes. Thermodynamics of Membrane Receptors and Channels will be valuable both as a learning aid and a reference for biophysicists, neuroscientists, cell biologists, physiologists, and other researchers investigating any aspects of biomembranes.

Thermodynamics of Membrane Receptors and Channels

Thermodynamics of Membrane Receptors and Channels PDF Author: Meyer B. Jackson
Publisher: CRC Press
ISBN: 9780849369087
Category : Science
Languages : en
Pages : 454

Get Book Here

Book Description
Thermodynamics of Membrane Receptors and Channels synthesizes a wealth of new information regarding the biophysics of membrane proteins. New insights provided by molecular genetics, single channel recording, and high resolution structural techniques are discussed from a conceptual perspective. Basic theoretical topics are introduced, developed, and then extensively illustrated with recent results from the literature or data from the authors' own laboratories. Theoretical and experimental information is incorporated into in-depth discussions of ion permeation mechanisms, ion channel and receptor conformational changes, aggregate activity of complexes of lipids and proteins, and how coupling is achieved between different energy modes in the many transduction systems residing in biomembranes. Thermodynamics of Membrane Receptors and Channels will be valuable both as a learning aid and a reference for biophysicists, neuroscientists, cell biologists, physiologists, and other researchers investigating any aspects of biomembranes.

Drug-Nucleic Acid Interactions

Drug-Nucleic Acid Interactions PDF Author:
Publisher: Elsevier
ISBN: 0080496903
Category : Medical
Languages : en
Pages : 740

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Book Description
This volume consolidates the key methods for studying ligand-nucleic acid interactions into a convenient source. Techniques that are examined range from biophysical and chemical approaches to methods rooted in molecular and cell biology.

Epigenetics and Biological Processes

Epigenetics and Biological Processes PDF Author: Gurbachan S. Miglani
Publisher: I K International Pvt Ltd
ISBN: 8197069549
Category : Science
Languages : en
Pages : 724

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Book Description
Epigenetics and Biological Processes deals with epigenetic control of various plant processes such as chromatin modification, biomacromolecule interactions, cell cycle, DNA replication, DNA recombination, DNA damage response, transcription, RNA processing and translation initiation, host restriction and modification, heterochromatin, euchromatin, centromere functions, telomeric maintenance, transposon activation, transposon silencing, transposon reactivation, photosynthesis, respiration, transpiration, polyploidisation, heterosis, homeostasis, cytoplasmic male sterility, self-incompatibility, circadian clocks, epigenetic imprinting, dosage compensation, somaclonal variation, plant stress response, plant-microbe interactions, disease responsive genes, and sustainable green revolution through epigenetics. Understanding epigenetics of these plant processes is essential for using science of epigenetics as a tool for crop improvement. This book is primarily designed as a textbook for senior/upper undergraduate (B.Sc. Agri.; B.Sc. Biotechnology and B.Tech. (Biotechnology) and graduate level (M.Sc. and Ph.D.) students studying epigenetics in conventional, agricultural and medical universities. Teachers and researchers in any discipline of life sciences, agricultural sciences, medicine, and biotechnology.

A Simple Equilibrium Statistical Mechanical Theory of Dense Hard Particle Fluids

A Simple Equilibrium Statistical Mechanical Theory of Dense Hard Particle Fluids PDF Author: H. Michael Ellerby
Publisher:
ISBN:
Category : Chemistry, Physical and theoretical
Languages : en
Pages : 446

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Book Description


Statistical Mechanics, Protein Structure, and Protein Substrate Interactions

Statistical Mechanics, Protein Structure, and Protein Substrate Interactions PDF Author: Sebastian Doniach
Publisher: Springer Science & Business Media
ISBN: 1489913491
Category : Science
Languages : en
Pages : 400

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Book Description
A number of factors have come together in the last couple of decades to define the emerging interdisciplinary field of structural molecular biology. First, there has been the considerable growth in our ability to obtain atomic-resolution structural data for biological molecules in general, and proteins in particular. This is a result of advances in technique, both in x-ray crystallography, driven by the development of electronic detectors and of synchrotron radiation x-ray sources, and by the development ofNMR techniques which allow for inference of a three-dimensional structure of a protein in solution. Second, there has been the enormous development of techniques in DNA engineering which makes it possible to isolate and clone specific molecules of interest in sufficient quantities to enable structural measurements. In addition, the ability to mutate a given amino acid sequence at will has led to a new branch of biochemistry in which quantitative measurements can be made assessing the influence of a given amino acid on the function of a biological molecule. A third factor, resulting from the exponential increase in computing power available to researchers, has been the emergence of a growing body of people who can take the structural data and use it to build atomic-scale models of biomolecules in order to try and simulate their motions in an aqueous environment, thus helping to provide answers to one of the most basic questions of molecular biology: the relation of structure to function.

Molecular Driving Forces

Molecular Driving Forces PDF Author: Ken Dill
Publisher: Garland Science
ISBN: 1136672982
Category : Science
Languages : en
Pages : 1026

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Book Description
Molecular Driving Forces, Second Edition E-book is an introductory statistical thermodynamics text that describes the principles and forces that drive chemical and biological processes. It demonstrates how the complex behaviors of molecules can result from a few simple physical processes, and how simple models provide surprisingly accurate insights into the workings of the molecular world. Widely adopted in its First Edition, Molecular Driving Forces is regarded by teachers and students as an accessible textbook that illuminates underlying principles and concepts. The Second Edition includes two brand new chapters: (1) "Microscopic Dynamics" introduces single molecule experiments; and (2) "Molecular Machines" considers how nanoscale machines and engines work. "The Logic of Thermodynamics" has been expanded to its own chapter and now covers heat, work, processes, pathways, and cycles. New practical applications, examples, and end-of-chapter questions are integrated throughout the revised and updated text, exploring topics in biology, environmental and energy science, and nanotechnology. Written in a clear and reader-friendly style, the book provides an excellent introduction to the subject for novices while remaining a valuable resource for experts.

Testing "native-state" Assumptions in Ligand Binding and Protein Structure Analysis

Testing Author: David Warren Miller
Publisher:
ISBN:
Category : Ligand binding (Biochemistry)
Languages : en
Pages : 284

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Book Description


Chemical Abstracts

Chemical Abstracts PDF Author:
Publisher:
ISBN:
Category : Chemistry
Languages : en
Pages : 2540

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Book Description


Computational Methods for Macromolecules: Challenges and Applications

Computational Methods for Macromolecules: Challenges and Applications PDF Author: Tamar Schlick
Publisher: Springer Science & Business Media
ISBN: 3642560806
Category : Mathematics
Languages : en
Pages : 504

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Book Description
This special volume collects invited articles by participants of the Third International Workshop on Methods for Macromolecular Modeling, Courant Institute of Mathematical Sciences, Oct. 12-14, 2000. Leading developers of methods for biomolecular simulations review advances in Monte Carlo and molecular dynamics methods, free energy computational methods, fast electrostatics (particle-mesh Ewald and fast multipole methods), mathematics, and molecular neurobiology, nucleic acid simulations, enzyme reactions, and other essential applications in biomolecular simulations. A Perspectives article by the editors assesses the directions and impact of macromolecular modeling research, including genomics and proteomics. These reviews and original papers by applied mathematicians, theoretical chemists, biomedical researchers, and physicists are of interest to interdisciplinary research students, developers and users of biomolecular methods in academia and industry.

Innovations in Biomolecular Modeling and Simulations

Innovations in Biomolecular Modeling and Simulations PDF Author: Tamar Schlick
Publisher: Royal Society of Chemistry
ISBN: 1849734615
Category : Biomolecules
Languages : en
Pages : 381

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Book Description
This two volume set describes innovations in biomolecular modeling and simulation, in both the algorithmic and application fronts.