A Case-control Study of Lifetime Participation in Recreational Physical Activity and Changes in Body Size in Relation to Breast Cancer PDF Download
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Author: Sybil Eng
Publisher:
ISBN:
Category :
Languages : en
Pages : 826
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Author: Sybil Eng
Publisher:
ISBN:
Category :
Languages : en
Pages : 826
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Author: Suzanne M. Shoff
Publisher:
ISBN:
Category :
Languages : en
Pages : 27
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Book Description
This postdoctoral training award supports studies to describe elements of energy balance and breast cancer incidence. The modifying effect of early-life body size and weight change on associations between early-life physical activity and breast cancer risk was evaluated using extant data from a case-control study of breast cancer. Cases (n=6888) were identified through four state-wide cancer registries; controls (n=9529) were randomly selected from population lists. Results suggest that, in premenopausal women, the relation between early-life physical activity and breast cancer risk is similar across all strata of early-life body size and weight change. In postmenopausal women, results suggest that risk reduction associated with physical activity may be greatest in women who were heaviest at age 18, and in women who maintained a stable weight between age 18 and 5 years prior to diagnosis, independent of initial weight. Preliminary data were obtained on intentional weight loss and weight reduction methods from the successful addition of relevant questions to an on-going case-control study of breast cancer. Responses to these questions suggest small, but potentially important, differences between cases and controls regarding patterns of intentional weight loss, choice of weight reduction method, and amount of weight lost.
Author: Kerry S. Courneya
Publisher: Springer Science & Business Media
ISBN: 3642042317
Category : Medical
Languages : en
Pages : 389
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Book Description
This book explores in depth the relation between physical activity and cancer control, including primary prevention, coping with treatments, recovery after treatments, long-term survivorship, secondary prevention, and survival. The first part of the book presents the most recent research on the impact of physical activity in preventing a range of cancers. In the second part, the association between physical activity and cancer survivorship is addressed. The effects of physical activity on supportive care endpoints (e.g., quality of life, fatigue, physical functioning) and disease endpoints (e.g., biomarkers, recurrence, survival) are carefully analyzed. In addition, the determinants of physical activity in cancer survivors are discussed, and behavior change strategies for increasing physical activity in cancer survivors are appraised. The final part of the book is devoted to special topics, including the relation of physical activity to pediatric cancer survivorship and to palliative cancer care.
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 756
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Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 1030
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Author: Jay R. Harris
Publisher: Lippincott Williams & Wilkins
ISBN: 1451148704
Category : Medical
Languages : en
Pages : 3432
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Book Description
Completely revised and updated, and now in full color throughout, the Fourth Edition of this definitive reference is a must for all clinicians who treat breast diseases. Leading experts summarize the current knowledge of breast diseases, including their clinical features, management, underlying biologies, and epidemiologies. In addition to complete coverage of malignant breast diseases, benign diseases are discussed in relation to subsequent breast cancer development. The book reviews all major clinical trials and summarizes the information they provide on early detection and management of breast cancer. Close attention is also given to the increasing importance of molecular biology and genetics in this field. This edition features more than thirty new contributors, fourteen new or completely rewritten chapters, and more clinically oriented chapters. A companion Website will offer the fully searchable text and an image bank. Also included with this edition is the Anatomical Chart Company's Breast Anatomy and Disorders Pocket Guide. This durable, portable folding pocket guide provides a visual and textual overview of breast anatomy, disorders, and breast self-examination. With a write-on, wipe-off laminated surface, this guide is perfect for the on-the-go practitioner to show patients, caregivers, and families.
Author: Jodi Wilson
Publisher:
ISBN:
Category : University of Ottawa theses
Languages : en
Pages :
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Although there is consistent evidence of an inverse association between physical activity and colorectal cancer (CRC), it is unclear whether physical activity has to be lifelong in order to protect against CRC, or whether there are critical time periods in which physical activity is most protective. This thesis investigated the association between recreational physical activities in specific age periods and across the lifetime and CRC risk in data from a population-based case control study (n=1395) in Newfoundland and Labrador. There were no significant associations between recreational physical activity at any age period or across the lifetime. Lack of association with activity in early adulthood is consistent with other studies in which this has been investigated. Lack of association in later life and across the lifetime may in part be explained by low levels of recreational physical activity, with only 30% of participants meeting World Cancer Research Fund cancer prevention recommendations.
Author:
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ISBN:
Category : Dissertation abstracts
Languages : en
Pages : 776
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Author: Lindsay Clare Kobayashi
Publisher:
ISBN:
Category :
Languages : en
Pages : 372
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Background: Moderate-to-vigourous intensity physical activity (MVPA) is among the few modifiable factors known to reduce breast cancer risk. However, the independent effects of leisure-time, household, and occupational MPVA by age period across the life course remain poorly understood. Whether these effects differ by menopausal status and by tumour subtypes defined by the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2) is unknown. An understanding of these issues will help advance policy and public health action targeting breast cancer prevention through physical activity. Methods: A case-control study of 1,011 incident breast cancer cases and 1,014 cancer-free controls aged 40-80 years was conducted from 2006-2010 in Vancouver, British Columbia (BC). Lifetime leisure-time, household, and occupational MVPA were assessed by questionnaire and mean MET-hrs/week of each were calculated for age periods 12-17, 18-34, 35-49, and [greater or equal to] 50 years and the total lifetime. Odds ratios for pre- and post-menopausal breast cancer risk associated with each activity domain across age periods were estimated using unconditional logistic regression, and odds ratios for risks of ER/PR-defined and ER/PR/HER2-defined breast tumours were estimated using unconditional polytomous logistic regression. Results: Among post-menopausal women, lifetime leisure-time and household MVPA reduced breast cancer risk by approximately 50% at volumes equal to 3 hours per week of running and 21 hours per week of active household work. MVPA reduced risk at all age periods across the life course, particularly during adulthood. Effects of leisure-time MVPA appeared restricted to HER2- tumours. Household MVPA reduced risk for ER/PR+ tumours, regardless of HER2 status. MVPA was not associated with pre-menopausal breast cancer risk, except occupational MVPA performed during ages 18-34 was associated with a doubling in risk. Conclusions: MVPA is a lifestyle factor women may engage in to reduce post-menopausal breast cancer risk. Results suggest HER2 may be implicated in anti-breast carcinogenic effects of leisure-time MVPA. Increased risk associated with occupational MVPA may be due to occupational exposures related to job intensity. Further research on specific aspects of weekly MVPA energy expenditure dose required to reduce breast cancer risk will aid in refining physical activity recommendations for breast cancer prevention.
Author: Rod K. Dishman
Publisher: Human Kinetics
ISBN: 1492581305
Category : Medical
Languages : en
Pages : 1316
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Book Description
Physical Activity Epidemiology, Second Edition, provides a comprehensive discussion of current population-level studies showing the influence of physical activity on disease. Updated with extensive new research collected in the eight years since the previous edition, the second edition adds the expertise of respected epidemiologist I-Min Lee. To assist readers in understanding the public health significance of physical activity, Dishman, Heath, and Lee present a detailed review of research findings and what those findings suggest regarding the relationship between physical activity and a variety of health risks. The second edition of this groundbreaking text has been exhaustively updated to reflect the wealth of new research published in this fast-moving field of study. With more than 100 pages of additional content, the text also offers more detailed coverage of all-cause and coronary heart disease mortality, expanded coverage of pathophysiology and biological plausibility, new information on physical activity among various racial–ethnic populations, and the effects of physical activity on cognitive function, dementia, and HIV/AIDS. More than 250 tables and figures, twice the number found in the previous edition, highlight the latest epidemiological information in an easy-to-understand visual format. Physical Activity Epidemiology, Second Edition, assists readers in understanding how leisure-time physical activity can enhance people’s quantity and quality of life by summarizing the available knowledge, detailing the methods used to obtain it, considering its implications for public health, and outlining the important questions that remain. Readers will find comprehensive discussion of these topics: • Evidence that physical activity protects against the development of coronary heart disease and stroke and premature death from all causes • Population-based studies and clinical experiments providing evidence that physical activity and exercise play a role in the primary and secondary prevention of mild hypertension, dyslipidemia, and obesity • Contemporary epidemiologic evidence that physical activity reduces the risk of type 2 diabetes and osteoporosis and protects against the development of breast and colon cancers, some inflammatory diseases, depression, and anxiety disorders • Considerations in the promotion of a safe, physically active lifestyle among all segments of the population Physical Activity Epidemiology, Second Edition, will engage and challenge students by examining the state of current research in all of its variation and even ambiguity. The text details the methodology and findings of classic and contemporary studies and then helps students begin to analyze the results. Special Strength of the Evidence sections found at the end of most chapters summarize the findings to determine the extent to which correlation and causation can be proven. Chapter objectives, chapter summaries, and sidebars in each chapter assist students in focusing on the key points of study, and an extensive glossary with detailed definitions provides a handy reference for review. Instructors will find a new image bank in this edition to enhance their class lecture materials. Physical Activity Epidemiology, Second Edition, offers students, sport and exercise scientists, health and fitness professionals, and public health administrators a comprehensive presentation of significant studies, how these studies contribute to understanding the relationship between activity and disease prevention, and how this information can be used in leading individuals, communities, and global society toward increased health and longevity.
