The Neurobiological Basis of Suicide

The Neurobiological Basis of Suicide PDF Author: Yogesh Dwivedi
Publisher: CRC Press
ISBN: 143983881X
Category : Medical
Languages : en
Pages : 485

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Book Description
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

The Neurobiological Basis of Suicide

The Neurobiological Basis of Suicide PDF Author: Yogesh Dwivedi
Publisher: CRC Press
ISBN: 143983881X
Category : Medical
Languages : en
Pages : 485

Get Book Here

Book Description
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Neuropsychopharmacology and the Affective Disorders

Neuropsychopharmacology and the Affective Disorders PDF Author: Joseph J. Schildkraut
Publisher: Little Brown GBR
ISBN:
Category : Medical
Languages : en
Pages : 138

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Book Description


Depression

Depression PDF Author: John F. Cryan
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805596057
Category : Medical
Languages : en
Pages : 283

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Book Description
What's new in antidepressant research? Despite the availability of antidepressants for over 40 years, a substantial proportion of depressed patients do not respond adequately to treatment. Failure to respond effectively to treatment contributes to physical ill-health and psychiatric morbidity, often resulting in premature death of the depressed patient. The purpose of this volume is to consider the possible reasons for the limitations of the currently available antidepressants, to examine the advances in our understanding of the psychopathology of depression and how such knowledge may assist in the discovery of new methods of treatment. Leading international experts in this field discuss the possible underlying reasons for depression and limitations of current antidepressants. Opportunities for novel therapeutic approaches to dysfunctional circadian rhythms and mood disorders as well as current status and future perspectives for optimizing antidepressant management of depression are reviewed. This publication illustrates the breadth of the latest research and is valuable reading for psychiatrists, neuroscientists and pharmacologists.

Biology of Schizophrenia and Affective Disease

Biology of Schizophrenia and Affective Disease PDF Author: Association for Research in Nervous and Mental Disease. Meeting
Publisher: American Psychiatric Pub
ISBN: 9780880487467
Category : Medical
Languages : en
Pages : 572

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Book Description
The Decade of the Brain has brought with it many advances in our understanding of the biology of major mental disorders. Biology of Schizophrenia and Affective Disease provides a state-of-the-art look at the biological bases of severe mental illness from the perspective of the researchers making these exceptional discoveries. In 17 chapters, some of the best investigators in the field furnish overviews of their ground-breaking findings and set course for future research efforts. From the biology of stress to excitotoxicity in the development of corticolimbic alterations in the schizophrenic brain, this outstanding reference tool explores the explosive progress in the fields of biochemistry, molecular genetics, neuroscience, and brain circuit anatomy and the resultant advances in nearly every aspect of the biology of the brain and mental illness. Dissolution of cerebral cortical mechanisms in patients with schizophrenia, linkage and molecular genetics in infantile autism, and postmortem studies of suicide victims and schizophrenic patients are among the topics covered. The book also discusses treatment issues, including the mechanisms of action of antidepressants and atypical antipsychotic drugs. Practitioners and students will find this volume an invaluable reference tool for understanding the mechanisms of normal and pathological brain function and potential areas for further insight into the biological bases of mental illness.

5-Hydroxytryptamine-3 Receptor Antagonists

5-Hydroxytryptamine-3 Receptor Antagonists PDF Author: Francis D. King
Publisher: CRC Press
ISBN: 9780849354632
Category : Medical
Languages : en
Pages : 384

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Book Description
5-Hydroxytryptamine-3 Receptor Antagonists provides a comprehensive, authoritative review of the topic featuring contributions by recognized leaders in the field. The book's three sections cover compound discovery and activity rationalization, the use of compounds for studying 5-HT3 receptors, and their applications to therapeutics. This book will be an important reference for oncologists, researchers working with the CNS and gastrointestinal disorders, and anyone working in the 5-HT field within the pharmaceutical arena, academia, and medical practice.

Neuropharmacology and Behavior

Neuropharmacology and Behavior PDF Author: Bernard Haber
Publisher: Springer Science & Business Media
ISBN: 1461339618
Category : Medical
Languages : en
Pages : 231

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Book Description
Science lost one of its distinguished researchers in the fields of biological psychiatry and neuropsychopharmacology on March 4, 1975, with the death of Harold Himwich. Some of his colleagues, friends, and former associates have expressed their esteem for this gentle person by the contribution of chapters in this book. Since this book can represent only an incomplete indication of Harold Himwich's influence, the editors have included his complete bibliography at the end of this volume. Harold Himwich's research career was divided into several phases, some of which overlapped. Starting with his first paper on rhabdomyoma of the ovary in 1920, he was entranced by research as well as by the puzzles and results which it promised. During the period that he was a resident and house officer at Bellevue Hospital in New York, he studied the physiology of muscular exercise. This work led him into studies of exercise in various types of disease. With Meyerhoff in Kiel, Germany, he began studying the respiratory quotient of muscle, and after returning to this country, he produced a number of papers on respiratory quotients of various organs including the brain.

Handbook of the Behavioral Neurobiology of Serotonin

Handbook of the Behavioral Neurobiology of Serotonin PDF Author: Christian Peter Müller
Publisher:
ISBN: 9780123746344
Category : Medical
Languages : en
Pages : 818

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Book Description
Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitters, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood, and pathological alterations in the serotonergic system underlie behaviour and psychiatric conditions (among a host of very successful drugs targeting the serotoninergic system are Prozac and Zoloft). This is the first truly integrated handbook providing a broad overview over the many face

Suicidal Behavior

Suicidal Behavior PDF Author: Maria A. Oquendo
Publisher:
ISBN: 9781416058700
Category : Suicidal behavior
Languages : en
Pages : 0

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Book Description
Each year in the United States 750,000 people attempt suicide; 30,000 will succeed. It remains the third leading cause of death for young people. This issue of Psychiatric Clinics of North America will examine the subject of suicide from a developmental perspective, emphasizing familial transmission and early onset suicidal behavior as well as prevention strategies.

5-HTP

5-HTP PDF Author: Michael T. Murray
Publisher: Bantam
ISBN: 9780553107845
Category : Health & Fitness
Languages : en
Pages : 312

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Book Description
5-HTP provides the most in-depth and clinically sound information yet available on this remarkable new amino acid supplement, which offers a safe, natural, less expensive alternative to prescription medications. As Dr. Murray has explained in featured appearances on ABC's "Prime Time Live" and "CBS Sunday Morning, " 5-HTP works by naturally boosting serotonin levels in the body. This is a powerful key to overcoming depression, obesity, insomnia, migraine headaches, PMS, fibromyalgia -- and other serotonin-related disorders.Dr. Murray includes numerous case histories from his own practice that show how to combine 5-HTP with other natural approaches. He also cites extensive American and European research, including double-blind studies showing that 5-HTP is highly safe and effective.

Basic Neurochemistry

Basic Neurochemistry PDF Author: George J. Siegel
Publisher: Lippincott Raven
ISBN:
Category : Medical
Languages : en
Pages : 1216

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Book Description
Illustrations by Lorie M. Gavulic, MFA Sponsored by the American Society for Neurochemistry.