3D Modelling of Mammalian Embryos and Organs

3D Modelling of Mammalian Embryos and Organs PDF Author: Silvia Garagna
Publisher: Frontiers Media SA
ISBN: 2889716074
Category : Science
Languages : en
Pages : 188

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Book Description

3D Modelling of Mammalian Embryos and Organs

3D Modelling of Mammalian Embryos and Organs PDF Author: Silvia Garagna
Publisher: Frontiers Media SA
ISBN: 2889716074
Category : Science
Languages : en
Pages : 188

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Book Description


Examining the State of the Science of Mammalian Embryo Model Systems

Examining the State of the Science of Mammalian Embryo Model Systems PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309676681
Category : Medical
Languages : en
Pages : 155

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Book Description
Because of the recent advances in embryo modeling techniques, and at the request of the Office of Science Policy in the Office of the Director at the National Institutes of Health, the National Academies of Sciences, Engineering, hosted a 1-day public workshop that would explore the state of the science of mammalian embryo model systems. The workshop, which took place on January 17, 2020, featured a combination of presentations, panels, and general discussions, during which panelists and participants offered a broad range of perspectives. Participants considered whether embryo model systems - especially those that use nonhuman primate cells - can be used to predict the function of systems made with human cells. Presentations provided an overview of the current state of the science of in vitro development of human trophoblast. This publication summarizes the presentation and discussion of the workshop.

Cell Polarity in Development and Disease

Cell Polarity in Development and Disease PDF Author: Douglas W Houston
Publisher: Academic Press
ISBN: 0128125918
Category : Science
Languages : en
Pages : 238

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Book Description
Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting cell polarity for translational medical research. - Provides basic science understanding of cell polarity disease and development - Covers diseases affecting polarized epithelial tissues in the lung and kidney, also covering the progression of cancer - Includes historical context of cell polarity research for potential future breakthroughs

Kaufman's Atlas of Mouse Development Supplement

Kaufman's Atlas of Mouse Development Supplement PDF Author: Richard Baldock
Publisher: Academic Press
ISBN: 0128009136
Category : Science
Languages : en
Pages : 343

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Book Description
Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. - Provides high-resolution images for best visualization of key developmental processes and structures - Offers in-depth anatomy and morphological views of organ systems - Written descriptions convey developmental origins of the organ systems

Culture Media, Solutions, and Systems in Human ART

Culture Media, Solutions, and Systems in Human ART PDF Author: Patrick Quinn
Publisher: Cambridge University Press
ISBN: 1139917358
Category : Medical
Languages : en
Pages : 307

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Book Description
This volume describes culture media and solutions used in human ART; how they have been developed for in vitro human pre-implantation embryo development, the function and importance of the various components in media and solutions and how they interact, and how the systems in which these are used can influence outcomes. Chapters discuss inorganic solutes, energy substrates, amino acids, macromolecules, cytokines, growth factors, buffers, pH, osmolality, and the interaction of these parameters. The role of incubators and other physical factors are reviewed, along with the relevance and prospects of emerging technologies: morphokinetic analysis using time-lapse imaging and dynamic fluid incubation systems. Results of prospective randomized trials are emphasized to ascertain the added value of these techniques for selecting viable embryos. This comprehensive guide will be invaluable for embryologists, physicians and all personnel involved in the fluid products used in human ART seeking to optimize their successful use of these components.

Early Mammalian Development

Early Mammalian Development PDF Author: Matthew H. Kaufman
Publisher: CUP Archive
ISBN: 9780521254496
Category : Nature
Languages : en
Pages : 296

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Book Description


The Dance of Life

The Dance of Life PDF Author: Magdalena Zernicka-Goetz
Publisher: Basic Books
ISBN: 1541699041
Category : Science
Languages : en
Pages : 238

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Book Description
A renowned biologist's cutting-edge and unconventional examination of human reproduction and embryo research Scientists have long struggled to make pregnancy easier, safer, and more successful. In The Dance of Life, developmental and stem-cell biologist Magdalena Zernicka-Goetz takes us to the front lines of efforts to understand the creation of a human life. She has spent two decades unraveling the mysteries of development, as a simple fertilized egg becomes a complex human being of forty trillion cells. Zernicka-Goetz's work is both incredibly practical and astonishingly vast: her groundbreaking experiments with mouse, human, and artificial embryo models give hope to how more women can sustain viable pregnancies. Set at the intersection of science's greatest powers and humanity's greatest concern, The Dance of Life is a revelatory account of the future of fertility -- and life itself.

Mechanisms of Cellular Differentiation, Organ Development, and Novel Model Systems

Mechanisms of Cellular Differentiation, Organ Development, and Novel Model Systems PDF Author: Benedetta Artegiani
Publisher: Frontiers Media SA
ISBN: 2832501192
Category : Science
Languages : en
Pages : 383

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Book Description


Practical Approach to Mammalian Cell and Organ Culture

Practical Approach to Mammalian Cell and Organ Culture PDF Author: Tapan Kumar Mukherjee
Publisher: Springer Nature
ISBN: 9811917310
Category : Medical
Languages : en
Pages : 1286

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Book Description
This Major Reference Work offers a detailed overview of culturing primary, secondary cell lines, tissues, and organs. It first introduces various types of mammalian cell cultures, infrastructure requirements for a mammalian cell-culture laboratory. The subsequent chapters present the detailed protocols for the isolation of mammalian hematologic organs and cells. It also discusses various cell-based assays for monitoring cell viability, cell proliferation, cytotoxicity, cell senescence, and cell death assays. In addition, the book addresses the various problems encountered while culturing animal cells, their possible causes, and suggested solutions, presenting detailed protocols for isolation and primary culturing of various mammalian cells and hematoimmunologic organs in two dimensions. Lastly, it reviews the various applications of animal-cell culture, stem-cell culture, and tissue and organ culture. As such, this reference book is highly relevant for students and professionals new to cell-culture work as well as to those wishing to expand their skills from cell-line cultures to primary cultures and from conventional 2D cultures to 3D cultures.

Examining the State of the Science of Mammalian Embryo Model Systems

Examining the State of the Science of Mammalian Embryo Model Systems PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309676711
Category : Medical
Languages : en
Pages : 155

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Book Description
Because of the recent advances in embryo modeling techniques, and at the request of the Office of Science Policy in the Office of the Director at the National Institutes of Health, the National Academies of Sciences, Engineering, hosted a 1-day public workshop that would explore the state of the science of mammalian embryo model systems. The workshop, which took place on January 17, 2020, featured a combination of presentations, panels, and general discussions, during which panelists and participants offered a broad range of perspectives. Participants considered whether embryo model systems - especially those that use nonhuman primate cells - can be used to predict the function of systems made with human cells. Presentations provided an overview of the current state of the science of in vitro development of human trophoblast. This publication summarizes the presentation and discussion of the workshop.