3D Cell-Based Biosensors in Drug Discovery Programs PDF Download
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Author: William S. Kisaalita
Publisher: CRC Press
ISBN: 1420073508
Category : Science
Languages : en
Pages : 406
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Book Description
Advances in genomics and combinatorial chemistry during the past two decades inspired innovative technologies and changes in the discovery and pre-clinical development paradigm with the goal of accelerating the process of bringing therapeutic drugs to market. Written by William Kisaalita, one of the foremost experts in this field, 3D Cell-Based Bio
Author: William S. Kisaalita
Publisher: CRC Press
ISBN: 1420073508
Category : Science
Languages : en
Pages : 406
Get Book Here
Book Description
Advances in genomics and combinatorial chemistry during the past two decades inspired innovative technologies and changes in the discovery and pre-clinical development paradigm with the goal of accelerating the process of bringing therapeutic drugs to market. Written by William Kisaalita, one of the foremost experts in this field, 3D Cell-Based Bio
Author: Huangxian Ju
Publisher: World Scientific
ISBN: 9811237727
Category : Science
Languages : en
Pages : 997
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Book Description
This book covers the full scope of biochemical sensors and offers a survey of the principles, design and applications of the most popular types of biosensing devices. It is presented in 19 chapters, written by 20 distinguished scientists as well as their co-workers. The topics include the design of signal transducers, signal tags and signal amplification strategies, the structure of biosensing interfaces with new biorecognition elements such as aptamers and DNAzymes, and different newly emerging nanomaterials such as Au nanoclusters, carbon nitride, silicon, upconversion nanoparticles and two-dimensional materials, and the applications in wearable detections, biofuel cells, biomarker analyses, bioimaging, single cell analysis and in vivo sensing.By discussing recent advances, it is hoped this book will bridge the common gap between research literature and standard textbooks. Research into biochemical sensors and their biomedical applications is proceeding in a number of exciting directions, as reflected by the content. This book is published in honor of the 90th birthday of Professor Shaojun Dong, who performed many pioneering studies on modified electrodes and biochemical sensors.
Author: Arun K. Bhunia
Publisher: Elsevier
ISBN: 0857098071
Category : Technology & Engineering
Languages : en
Pages : 550
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Book Description
Recent advances in array-based detectors and imaging technologies have provided high throughput systems that can operate within a substantially reduced timeframe and other techniques that can detect multiple contaminants at one time. These technologies are revolutionary in terms of food safety assessment in manufacturing, and will also have a significant impact on areas such as public health and food defence. This book summarizes the latest research and applications of sensor technologies for online and high throughput screening of food. The book first introduces high throughput screening strategies and technology platforms, and discusses key issues in sample collection and preparation. The subsequent chapters are then grouped into four sections: Part I reviews biorecognition techniques; Part II covers the use of optical biosensors and hyperspectral imaging in food safety assessment; Part III focuses on electrochemical and mass-based transducers; and finally Part IV deals with the application of these safety assessment technologies in specific food products, including meat and poultry, seafood, fruits and vegetables. - Summarises the latest research on sensor technologies for online and high-throughput screening of food - Covers high-throughput screening and the current and forecast state of rapid contaminant detection technologies - Looks at the use of optical and electrochemical biosensors and hyperspectral imaging in food safety assessment and the application of these technologies in specific food products
Author: William Kisaalita
Publisher: Cambridge Scholars Publishing
ISBN: 1527558940
Category : Business & Economics
Languages : en
Pages : 307
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Book Description
This book details the development and evaluation of technological interventions designed to improve human and economic development within complex, low-resource settings, showing that a solution becomes an innovation when it reaches widespread use. The book shortens the time-gap between development and up-take of the intervention, especially for student solution-developers or innovators who are new to the cultural and geopolitical settings of the problem-source country or region. Technological interventions in development are sustainable if they meet a real need, are affordable by the users, fit within the cultural context and are ergonomically appropriate. Many interventions have failed because of inattentiveness to one or more of these factors. Each of the book’s points is backed up with scholarly research work, confidently guiding solution-developers confronted with issues such as acquiring intellectual property protections, among many others.
Author: Qingjun Liu
Publisher: Artech House
ISBN: 1596934409
Category : Medical
Languages : en
Pages : 291
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Book Description
Written by recognized experts the field, this leading-edge resource is the first book to systematically introduce the concept, technology, and development of cell-based biosensors. You find details on the latest cell-based biosensor models and novel micro-structure biosensor techniques. Taking an interdisciplinary approach, this unique volume presents the latest innovative applications of cell-based biosensors in a variety of biomedical fields. The book also explores future trends of cell-based biosensors, including integrated chips, nanotechnology and microfluidics. Over 140 illustrations help clarify key topics throughout the book.
Author: Theodore P. Rasmussen
Publisher: John Wiley & Sons
ISBN: 111928323X
Category : Science
Languages : en
Pages : 385
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Book Description
This book contains material contributed by forward-looking scientists who work at the interface of stem cell research and applied science with the aim to improve human fetal safety and the understanding of human developmental and degenerative disorders. Provides important platforms and contemporary accounts of the state of stem cell research in the fields of toxicology and teratology Considers both in vitro uses of stem cells as platforms for teratology and also stem cellopathies, which are in vivo developmental and degenerative disorders Helps the pharmaceutical industry and safety and environmental authorities validate the status quo of in vitro toxicity test systems based on human pluripotent stem cells and their derivatives
Author: Manabu Tokeshi
Publisher: MDPI
ISBN: 3038425346
Category : Technology & Engineering
Languages : en
Pages : 229
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Book Description
This book is a printed edition of the Special Issue "Micro/Nano Devices for Chemical Analysis" that was published in Micromachines
Author: Silvia Scaglione
Publisher: Frontiers Media SA
ISBN: 2889740153
Category : Medical
Languages : en
Pages : 90
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Book Description
Author: Alexander Birbrair
Publisher: Academic Press
ISBN: 0323983987
Category : Science
Languages : en
Pages : 638
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Book Description
Current Topics in iPSCs provides a deep analysis of the underlying fundamentals that support short and mid-term developments and milestones in the business of mesenchymal stem cell therapies. This volume explores the next frontier of MSC therapies and how the transformational potential of therapeutic adult cells will be realised in all therapy areas. The impacts of clinical and economic benefits are dissected throughout each of the chapters. Written by thought leaders in the field for those curious about the interface of science and business. - Explores the strategy at the forefront of the science of mesenchymal stem cells - Provides an overview of all therapy areas where MSC and MSC-derived products can be used therapeutically - Depicts transformational changes in healthcare that enable the implementation of MSC-powered technology platforms
Author: Khawaja Husnain Haider
Publisher: Springer Nature
ISBN: 9811926557
Category : Science
Languages : en
Pages : 1527
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Book Description
The handbook comprehensively reviews the therapeutic potential of stem cells and stem cell secretome-based cell-free strategies in regenerative medicine. The chapters in section I and section II respectively discuss the diverse applications of mesenchymal stem cells and non- mesenchymal stem cells, including skeletal myoblasts, endothelial progenitor cells, adipose tissue-derived stem cells, induced pluripotent stem cells, and neuronal stem cells in myocardial repair, inflammatory bowel disease, cognitive deficits, wound healing, retinal disorders, and COVID-19. The subsequent chapters in section IIIprimarily focused on the fast-emerging cell-free therapy approach in regenerative medicine for tissue repair and regeneration. These chapters review the impact of stem cell-derived secretome on various biological processes such as angiogenesis, neurogenesis, tissue repair, immunomodulation, musculoskeletal pathologies, wound healing, anti-fibrotic, and anti-tumorigenesis for tissue maintenance and regeneration.Lastly, section IV summarizes miscellaneous aspects of cell-based therapy, includingthe treatment advantages, opportunities, and shortcomings in stem cell-based therapy, potentially helping to refine future studies and translate them from experimental to clinical studies. Moreover, this section also has chapters on cancer stem cells as novel targets in cancer therapeutics. This Major Reference Book (MRW) is a valuable resource for researchers involved in stem cell research to understand the multifaceted therapeutic applications of stem cells and their derivative secretome in regenerative medicine.
