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Author: Donald Clayton
Publisher: States Academic Press
ISBN: 9781639895755
Category : Science
Languages : en
Pages : 208
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Book Description
The zebrafish is a tropical freshwater fish belonging to the carp family of the order Cypriniformes. It is a popular aquarium fish native to South America. The name comes from the horizontal blue stripes on their body which resembles a zebra. The zebrafish is an important and widely used vertebrate model organism in scientific research, particularly drug development. It has remarkable regenerative abilities, and has been modified by scientists to produce many transgenic strains. The zebra fish shares 70% of its genes with the humans and has many organs similar to that of humans. Hence any type of disease which affects human body parts can also be remodelled in a zebrafish. This book provides comprehensive insights into the study of zebrafish. From theories to research to practical applications, case studies related to all contemporary topics of relevance to this field have been included herein. A number of latest researches have been included in this book to keep the readers up-to-date with the global concepts in this area of study.
Author: Donald Clayton
Publisher: States Academic Press
ISBN: 9781639895755
Category : Science
Languages : en
Pages : 208
Get Book Here
Book Description
The zebrafish is a tropical freshwater fish belonging to the carp family of the order Cypriniformes. It is a popular aquarium fish native to South America. The name comes from the horizontal blue stripes on their body which resembles a zebra. The zebrafish is an important and widely used vertebrate model organism in scientific research, particularly drug development. It has remarkable regenerative abilities, and has been modified by scientists to produce many transgenic strains. The zebra fish shares 70% of its genes with the humans and has many organs similar to that of humans. Hence any type of disease which affects human body parts can also be remodelled in a zebrafish. This book provides comprehensive insights into the study of zebrafish. From theories to research to practical applications, case studies related to all contemporary topics of relevance to this field have been included herein. A number of latest researches have been included in this book to keep the readers up-to-date with the global concepts in this area of study.
Author: Samuel Cartner
Publisher: Academic Press
ISBN: 0128124326
Category : Science
Languages : en
Pages : 720
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Book Description
The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research. - Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications - Includes the work of world-renowned authors - Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series
Author: Allan V. Kalueff
Publisher: Humana Press
ISBN: 9781607619215
Category : Medical
Languages : en
Pages : 296
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Book Description
Animal models have traditionally played a crucial role in improving our understanding of brain pathogenesis. Zebrafish (Danio rerio) have generated considerable discoveries in the areas of genetics, embryology, endocrinology, and neuroscience. Zebrafish Models in Neurobehavioral Research emphasizes the growing importance of zebrafish in neurobehavioral research and portrays an extensive, thorough perspective on the emergence of zebrafish as robust and translational models. Written by leading international experts, the book covers major topics ranging from stress to learned recognition of environment, encompassing a wide spectrum of the utility of zebrafish within neurobiological disciplines. The chapters provide authoritative reviews of many zebrafish paradigms commonly used in the field today. This book will be a useful guide for zebrafish researchers, and will complement another related book from the popular Neuromethods series, Zebrafish Neurobehavioral Protocols. Comprehensive and up-to-date, Zebrafish Models in Neurobehavioral Research serves as an ideal resource for scientists new to the field as well as for established researchers seeking valuable insight into the growing utility of zebrafish in neuroscience.
Author: Robert T. Gerlai
Publisher: Academic Press
ISBN: 012817529X
Category : Medical
Languages : en
Pages : 616
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Book Description
Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and current concepts pertinent to their neurobehavioral genetics. Discussing their natural behavior, motor function, learning and memory, this book focuses on the fry and adult zebrafish, featuring a comprehensive account of modern genetic and neural methods adapted to, or specifically developed for, Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish are presented, as is a section on bioinformatics and "big-data" related questions. - Provides the most comprehensive snapshot of the fast-evolving zebrafish neurobehavior genetics field - Describes behavioral, genetic and neural methods and concepts for use in adult and larval zebrafish - Features examples of zebrafish models of human central nervous system disorders - Discusses bioinformatics questions pertinent to zebrafish neurobehavioral genetics
Author: Allan V. Kalueff
Publisher: Humana Press
ISBN: 9781617795961
Category : Medical
Languages : en
Pages : 0
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Book Description
Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research. Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders. Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe.
Author: Prasan R. Bhandari
Publisher: Springer Nature
ISBN: 9811652171
Category : Medical
Languages : en
Pages : 493
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Book Description
This book provides the latest information on the significance of zebrafish as an ideal model for researching the biomedical field, with references. This book also focused on the evidence of zebrafish as a model in cardiovascular, neurologic, psychiatric and metabolic research. In addition, the book also includes the research carried out on zebrafish in hepatic, renal, ophthalmic, and ENT related areas. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish models including specific research in the area of skin disorders, endocrine diseases, nutritional disorders, gastrointestinal, hematological disorders and cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and its suitability for modeling various diseases, providing a critical resource on the potential attributes of the zebrafish as a pharmacological model. In terms of scope, this book is a useful tool for young researchers, professors and pharmaceutical scientists for understanding the significance of zebrafish as an emerging pharmacological model that can significantly aid in the process of drug discovery and development.
Author: H. William Detrich III
Publisher: Academic Press
ISBN: 0123751616
Category : Science
Languages : en
Pages : 399
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Book Description
Due to its prolific reproduction and the external development of the transparent embryo, the zebrafish is the prime model for genetic and developmental studies, as well as research in genomics. While genetically distant from humans, nonetheless the vertebrate zebrafish has comparable organs and tissues that make it the model organism for study of vertebrate development.This book, one of two new volumes in the Reliable Lab Solutions series dealing with zebrafish, brings together a robust and up-to-date collection of time-tested methods presented by the world's leading scientists. Culled from previously published chapters in Methods in Cell Biology and updated by the original authors where relevant, it provides a comprehensive collection of protocols describing the most widely used techniques relevant to the study of zebrafish genetics and genomics. The methods in this volume were hand-selected by the editors, whose goal was to a provide a handy and cost-effective collection of fail-safe methods, tips, and "tricks of the trade" to both experienced researchers and more junior members in the lab. - Provides busy researchers a quick reference for time-tested methods and protocols that really work, updated where possible by the original authors - Gives pragmatic wisdom to the non-specialist from experts in the field with years of experience with trial and error
Author:
Publisher: Academic Press
ISBN: 0128033436
Category : Medical
Languages : en
Pages : 386
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Book Description
Zebrafish at the Interface of Development and Disease Research presents the latest on the shared pathways that govern development and contribute to disease. Zebrafish have traditionally been used to study vertebrate development, providing interesting data on the developmental processes and genes that are implicated in disease. This new release in the series contains informative discussions on congenital heart defects in zebrafish, the use of zebrafish in studying kidney development and disease, and muscle development, homeostasis and disease in zebrafish. Each chapter interweaves the study of zebrafish development and its application to the immune system, the kidney, liver, heart and others. - The subject matter is unique - no single volume has pulled together the theme of development and disease with zebrafish as a centerpiece - Leading experts in the field - all of them running zebrafish focused labs for each chapter
Author: Robert Bryson-Richardson
Publisher: Academic Press
ISBN: 0080920616
Category : Science
Languages : en
Pages : 239
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Book Description
Zebrafish are widely considered an excellent model system for vertebrate development. The embryo is transparent, thereby enabling visualization and use of labelling and transgenic approaches. Moreover, because of the ease of inducing new mutations in zebrafish and similarity with the human genome, this organism may be used effectively for disease studies. For example, mutant zebrafish are being utilized for testing drugs that will combat a range of human diseases, from Alzheimer's and cancer to kidney failure and congenital heart disease. For the first time, this atlas provides the research community with a complete reference for zebrafish anatomy spanning the early embryo all the way to adulthood. The authors employ the technique of optical projection tomography (OPT), and offer a series of sections in multiple planes from each sample. The contents are organized by developmental stages, with over 200 images that contain annotations describing anatomical structures relevant to development. In addition, chapters feature explanatory text that highlights major developments in the zebrafish during each stage. - Provides the first comprehensive anatomical resource that covers all regions of zebrafish anatomy from the larval period to adulthood - The over 200 images include explanatory notes - Each chapter contains a concise description of key anatomical features that factor in zebrafish development - Despite many years of use as a model system, until now there has never been a guide to zebrafish at the larval stage - The book's website contains a database of over 10k sections from different regions as well as 3D images that are interactive
Author: Marley J Thompson
Publisher: Independently Published
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
The zebrafish is a tropical freshwater fish belonging to the carp family of the order Cypriniformes. It is a popular aquarium fish native to South America. The name comes from the horizontal blue stripes on their body which resembles a zebra. The zebrafish is an important and widely used vertebrate model organism in scientific research, particularly drug development. It has remarkable regenerative abilities, and has been modified by scientists to produce many transgenic strains. The zebra fish shares 70% of its genes with the humans and has many organs similar to that of humans. Hence any type of disease which affects human body parts can also be remodelled in a zebrafish. This book provides comprehensive insights into the study of zebrafish. From theories to research to practical applications, case studies related to all contemporary topics of relevance to this field have been included herein. A number of latest researches have been included in this book to keep the readers up-to-date with the global concepts in this area of study. This book makes the perfect gift for anyone that is a zebrafish fan.
