Author: Nobutami Kasai
Publisher:
ISBN:
Category : Macromolecules
Languages : en
Pages : 578

Get Book Here

Book Description
Publisher description

Author: ... Kasai-Kakudo
Publisher:
ISBN: 9784062074056
Category : Macromolecules
Languages : en
Pages : 504

Get Book Here

Book Description

Author: George H. Stout
Publisher: John Wiley & Sons
ISBN: 0471607118
Category : Science
Languages : en
Pages : 484

Get Book Here

Book Description
Closely follows an actual structural determination. After some introductory material on the nature of x-rays, the diffraction process, and the internal geometry of crystals, the selection and preparation of a crystal are considered. Techniques of measuring raw x-ray data are covered, plus their reduction into a useable form. The second part discusses both traditional and novel methods of solving the ``phase'' problem, the principal difficulty in x-ray structure determination. The third part considers how to extract the most information from the data and how to evaluate its reliability. Finally, there is a discussion of sources of error in practice and interpretation.

Author: Nobutami Kasai
Publisher: Springer
ISBN: 9783642064579
Category : Science
Languages : en
Pages : 0

Get Book Here

Book Description
The audience for this thorough overview includes advanced undergraduates and postgraduate researchers in macromolecular sciences who can benefit from more familiarity with the use of X-ray diffraction for obtaining structural information on biological substances, natural and synthetic high polymeric materials. X-Ray Diffraction by Macromolecules comprises three parts: fundamental, experimental and analytical, and the volume as a whole may serve as an intermediate textbook to bridge the treatments found in primers and specialist works. It presents a thorough treatment of principles and applications, and gives full, practical details on experimental methods and the treatment of results, along with many examples of actual analysis.

Author: Bernhard Rupp
Publisher: Garland Science
ISBN: 1134064195
Category : Science
Languages : en
Pages : 832

Get Book Here

Book Description
Synthesizing over thirty years of advances into a comprehensive textbook, Biomolecular Crystallography describes the fundamentals, practices, and applications of protein crystallography. Illustrated in full-color by the author, the text describes mathematical and physical concepts in accessible and accurate language. Biomolecular Crystallography will be a valuable resource for advanced undergraduate and graduate students and practitioners in structural biology, crystallography, and structural bioinformatics.

Author: Alexander McPherson
Publisher: John Wiley & Sons
ISBN: 1118210638
Category : Science
Languages : en
Pages : 284

Get Book Here

Book Description
A comprehensive and approachable introduction to crystallography — now updated in a valuable new edition The Second Edition of this well-received book continues to offer the most concise, authoritative, and easy-to-follow introduction to the field of crystallography. Dedicated to providing a complete, basic presentation of the subject that does not assume a background in physics or math, the book's content flows logically from basic principles to methods, such as those for solving phase problems, interpretation of Patterson maps and the difference Fourier method, the fundamental theory of diffraction and the properties of crystals, and applications in determining macromolecular structure. This new edition includes a vast amount of carefully updated materials, as well as two completely new chapters on recording and compiling X-ray data and growing crystals of proteins and other macromolecules. Richly illustrated throughout to clarify difficult concepts, this book takes a non-technical approach to crystallography that is ideal for professionals and graduate students in structural biology, biophysics, biochemistry, and molecular biology who are studying the subject for the first time.

Author: Jan Drenth
Publisher: Springer Science & Business Media
ISBN: 1475730926
Category : Science
Languages : en
Pages : 355

Get Book Here

Book Description
New textbooks at all levels of chemistry appear with great regularity. Some fields such as basic biochemistry, organic reaction mechanisms, and chemical thermodynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research that is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive intro ductions to their fields. These should serve the needs of one-semester or one-quarter graduate courses in chemistry and biochemistry. In some cases, the availability of texts in active research areas should help stimulate the creation of new courses. Charles R. Cantor v Preface to the Second Edition Since the publication of the previous edition in 1994, X-ray crystallography of proteins has advanced by improvements in existing techniques and by addition of new techniques.

Author: Gale Rhodes
Publisher: Academic Press
ISBN: 0323137784
Category : Science
Languages : en
Pages : 217

Get Book Here

Book Description
Crystallography Made Crystal Clear is designed to meet the need for an X-ray analysis that is between brief textbook sections and complete treatments. The book provides non-crystallographers with an intellectually satisfying explanation of the principles of how protein models are gleaned from X-ray analysis. The understanding of these concepts will foster wise use of the models, including the recognition of the strengths and weaknesses of pictures or computer graphics. Since proteins comprise the majority of the mass of macromolecules in cells and carry out biologically important tasks, the book will be of interest to biologists.Provides accessible descriptions of principles of x-ray crystallography, built on simple foundations for anyone with a basic science backgroundLeads the reader through clear, thorough, unintimidating explanations of the mathematics behind crystallographyExplains how to read crystallography papers in research journalsIf you use computer-generated models of proteins or nucleic acids for:Studying molecular interactionsDesigning ligands, inhibitors, or drugsEngineering new protein functionsInterpreting chemical, kinetic, thermodynamic, or spectroscopic dataStudying protein foldingTeaching macromolecule structure,and if you want to read new structure papers intelligently; become a wiser user of macromolecular models; and want to introduce undergraduates to the important subject of x-ray crystallography, then this book is for you.

Author: Mark R. Sanderson
Publisher: Oxford University Press
ISBN: 0198520972
Category : Language Arts & Disciplines
Languages : en
Pages : 293

Get Book Here

Book Description
Macromolecular crystallography is the study of macromolecules using X-ray crystallographic techniques to determine their molecular structure. This title synthesises contributions from a team of internationally recognized leaders, offering chapters on conventional and high-throughput methods.

Author: Maria Armenia Carrondo
Publisher: Springer
ISBN: 9400725302
Category : Science
Languages : en
Pages : 213

Get Book Here

Book Description
This volume is a collection of the contributions presented at the 42nd Erice Crystallographic Course whose main objective was to train the younger generation on advanced methods and techniques for examining structural and dynamic aspects of biological macromolecules. The papers review the techniques used to study protein assemblies and their dynamics, including X-ray diffraction and scattering, electron cryo-electron microscopy, electro nanospray mass spectrometry, NMR, protein docking and molecular dynamics. A key theme throughout the book is the dependence of modern structural science on multiple experimental and computational techniques, and it is the development of these techniques and their integration that will take us forward in the future.