Women in Microbiome in Health and Disease 2021

Women in Microbiome in Health and Disease 2021 PDF Author: Elisabetta Caselli
Publisher: Frontiers Media SA
ISBN: 2832505848
Category : Science
Languages : en
Pages : 177

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Book Description

Women in Microbiome in Health and Disease 2021

Women in Microbiome in Health and Disease 2021 PDF Author: Elisabetta Caselli
Publisher: Frontiers Media SA
ISBN: 2832505848
Category : Science
Languages : en
Pages : 177

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Book Description


The Female Reproductive Tract Microbiome - Gatekeeper for Sexual and Reproductive Health

The Female Reproductive Tract Microbiome - Gatekeeper for Sexual and Reproductive Health PDF Author: Mariya Ivanova Petrova
Publisher: Frontiers Media SA
ISBN: 2889767477
Category : Science
Languages : en
Pages : 267

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Book Description
An optimal female reproductive tract (FRT) microbiome represents a cornerstone for successful reproductive and sexual health. Although understanding the link between the microbiota and our health is the focus of a growing number of research programs and research has advanced in the last decade, the FRT microbiome remains relatively poorly defined. This is despite it being one of the most critical factors impacting fertility and the health of the future generation. Important gaps in our knowledge remain about women-specific microbial niches, such as the lower FRT. The vaginal microbiome of healthy women is almost exclusively dominated by Lactobacillus species, making these species synonymous with vaginal health. Largely thanks to their capacity to produce high levels of lactic acid, lactobacilli are thought to inhibit most invading bacterial and viral pathogens. Nonetheless, the dogma that all Lactobacillus species are key beneficial species in the vaginal niche has been questioned, based on the association with disease for some of the major players in the niche, for example L. iners, particularly in non-European or Caucasian cohorts. Further, the ability of other (mostly anaerobic) species besides lactobacilli, to maintain similar homeostasis in the vaginal niche raises the question of what we define as optimal or healthy vaginal microbiota. Answering this question is essential since a non-optimal or dysbiotic vaginal microbiome has been linked to the acquisition of sexually transmitted infections (STIs), infertility, and adverse pregnancy outcomes. To confront these healthcare challenges we should be able to distinguish between an optimal and non-optimal microbiome. With the advance of sequence-based technologies, as well as other omics methodologies, including metaproteomics, metabolomics and culturomics, we are now able to begin to correlate the presence, as well as the activities, of specific organisms and microbial communities with health or disease. However, we are only beginning to understand the complexity of interactions between bacterial community members with each other and the human host. A better understanding of these relationships within this specialized environmental niche and in relation to female sexual and reproductive health is critical for the development of novel diagnostics and therapeutics to create and maintain an optimal FRT microbiome.

The Human Microbiota

The Human Microbiota PDF Author: David N. Fredricks
Publisher: John Wiley & Sons
ISBN: 1118409809
Category : Science
Languages : en
Pages : 348

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Book Description
The Human Microbiota offers a comprehensive review of all human-associated microbial niches in a single volume, focusing on what modern tools in molecular microbiology are revealing about human microbiota, and how specific microbial communities can be associated with either beneficial effects or diseases. An excellent resource for microbiologists, physicians, infectious disease specialists, and others in the field, the book describes the latest research findings and evaluates the most innovative research approaches and technologies. Perspectives from pioneers in human microbial ecology are provided throughout.

The Lung Microbiome

The Lung Microbiome PDF Author: Michael J. Cox
Publisher: European Respiratory Society
ISBN: 1849841020
Category : Medical
Languages : en
Pages : 261

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Book Description
Studying the lung microbiome requires a specialist approach to sampling, laboratory techniques and statistical analysis. This Monograph introduces the techniques used and discusses how respiratory sampling, 16S rRNA gene sequencing, metagenomics and the application of ecological theory can be used to examine the respiratory microbiome. It examines the different components of the respiratory microbiome: viruses and fungi in addition to the more frequently studied bacteria. It also considers a range of contexts from the paediatric microbiome and how this develops to disease of all ages including asthma and chronic obstructive pulmonary disease, chronic suppurative lung diseases, interstitial lung diseases, acquired pneumonias, transplantation, cancer and HIV, and the interaction of the respiratory microbiome and the environment.

Research on Women's Health

Research on Women's Health PDF Author:
Publisher:
ISBN:
Category : Women
Languages : en
Pages : 84

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Book Description


Missing Microbes

Missing Microbes PDF Author: Martin J. Blaser, MD
Publisher: Henry Holt and Company
ISBN: 0805098119
Category : Science
Languages : en
Pages : 289

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Book Description
“In Missing Microbes, Martin Blaser sounds [an] alarm. He patiently and thoroughly builds a compelling case that the threat of antibiotic overuse goes far beyond resistant infections.”—Nature Renowned microbiologist Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the equilibrium and health of our bodies. Now this invisible Eden is under assault from our overreliance on medical advances including antibiotics and caesarian sections, threatening the extinction of our irreplaceable microbes and leading to severe health consequences. Taking us into the lab to recount his groundbreaking studies, Blaser not only provides elegant support for his theory, he guides us to what we can do to avoid even more catastrophic health problems in the future. “Missing Microbes is science writing at its very best—crisply argued and beautifully written, with stunning insights about the human microbiome and workable solutions to an urgent global crisis.”—David M. Oshinsky, author of the Pulitzer Prize-winning Polio: An American Story

Maternal Microbiome in Health and Disease: Advances and Possible Outcomes

Maternal Microbiome in Health and Disease: Advances and Possible Outcomes PDF Author: Carla R. Taddei
Publisher: Frontiers Media SA
ISBN: 288976222X
Category : Science
Languages : en
Pages : 225

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Book Description


The Gut Microbiome in Health and Disease

The Gut Microbiome in Health and Disease PDF Author: Dirk Haller
Publisher: Springer
ISBN: 3319905457
Category : Medical
Languages : en
Pages : 355

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Book Description
The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

The Human Microbiome in Early Life

The Human Microbiome in Early Life PDF Author: Omry Koren
Publisher: Academic Press
ISBN: 0128180978
Category : Science
Languages : en
Pages : 326

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Book Description
The Human Microbiome in Early Life: Implications to Health and Disease presents recent research advances that have highlighted the significance of early life, possibly beginning before birth, in the establishment of both the microbiome and its role in health and disease. The book reviews current knowledge on the origins of the human microbiota in early life, presents exposures which may disturb normal microbial colonization, and covers their implications to the risk of disease. Finally, emerging means to modify the early human microbiome to improve health are discussed.

Reviews in Microbiome in Health & Disease

Reviews in Microbiome in Health & Disease PDF Author: Suhana Chattopadhyay
Publisher: Frontiers Media SA
ISBN: 2832549896
Category : Science
Languages : en
Pages : 164

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Book Description
Frontiers in Cellular and Infection Microbiology is delighted to present the Reviews in series of article collections.